| NCT04188327 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Stellate Ganglion Block in Herpes Zoster |
Interventional |
Not Applicable
|
Pain,Neuropathic
|
2020-05-01 |
2021-04-14 |
Tanta University |
No
|
| NCT04493216 |
BFA
|
Investigational Site Number 2040001; Cotonou;
|
A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults |
Interventional |
Phase 2
|
HIV Infections
|
2020-11-19 |
2028-02-16 |
ViiV Healthcare |
No
|
| PACTR202008763735746 |
|
|
Pericapsular Nerve Group (PENG) Block for Hip Fracture; a prospective randomized controlled trial |
RCT |
|
perioperative analgesia for hip fracture surgery
|
70-01-01 |
70-01-01 |
Tanta University Faculty of Medicine |
No
|
| NCT01619540 |
TUN
|
Fottouma Bourguiba University Hospital; Monastir;
|
Valsalva Manœuvre in the Diagnosis of Left Ventricular Failure in Chronic Obstructive Pulmonary Disease Exacerbation |
Interventional |
Not Applicable
|
COPD Exacerbation,Acute Heart Failure
|
2011-05-01 |
2013-06-01 |
University of Monastir |
No
|
| NCT01868737 |
ZAF
|
Tygerberg Hospital; Parrow;
|
Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature Infants |
Interventional |
Phase 3
|
Necrotizing Enterocolitis
|
2011-07-01 |
2012-08-01 |
University of Stellenbosch |
No
|
| NCT01386138 |
|
|
Treating South African Pregnant Women for Methamphetamine |
Interventional |
Not Applicable
|
HIV,Drug Addiction
|
2011-07-01 |
2013-06-01 |
RTI International |
No
|
| NCT02103452 |
Egypt
|
Al-Azhar University; Cairo;
|
Edessy Stem Cell Score (ESS), Endometrium, Endometrioma |
Interventional |
Not Applicable
|
Endometriosis, Ovarian
|
2012-10-01 |
2013-10-01 |
Al-Azhar University |
No
|
| NCT03324009 |
NGA
|
Princess Marina Hospital; Port Harcourt;
|
2-stage Cervical Cancer Screening in Botswana |
Interventional |
Not Applicable
|
HIV/AIDS,Cervical Cancer
|
2018-04-20 |
2020-01-31 |
Beth Israel Deaconess Medical Center |
No
|
| NCT03276273 |
EGY
|
Theodor Bilharz Research Institute; Giza; (TBRI)
|
Bispectral-Electroencephalography (EEG) in First Time Hemodialysis |
Observational |
|
Renal Failure Acute Chronic
|
2017-05-01 |
2021-12-01 |
Suez Canal University |
No
|
| NCT00074152 |
|
|
Adjuvant Chemotherapy in Treating Women Who Have Undergone Resection for Relapsed Breast Cancer; Chemotherapy as Adjuvant for LOcally Recurrent Breast Cancer |
Interventional |
Phase 3
|
Breast Cancer
|
2002-07-01 |
2016-08-22 |
International Breast Cancer Study Group |
No
|
| NCT04424316 |
EGY, Senegal, BWA, ZAF, ZMB, South Africa, TUN, KEN, SEN, Ghana, NGA, Benin, Ethiopia, GMB, Uganda, COD, DZA, RWA, UGA, TZA, ZWE, Kenya, GHA, MOZ, Nigeria, NAM, Togo, LBR, Zambia, CMR, MWI
|
Clinical Research Center - Cairo University; Giza;
University of Thies; Thies; (UT)
BHP Study Clinic Gaborone Shapiro - Princess Marina Hospital; Gaborone; (CRS)
Francistown Academic Hospital; Francistown;
Clinical Research Unit; Gauteng;
Ipafu Rural Health Centre; Copperbelt;
TASK Clinical Research Centre; Bellville;
Choma District Health Office; Choma;
Synopsis Research; Cape Town;
Clintrial Consultants; Cape Town;
Centre for Medical Excellence; Sandton;
Queenswood CTC; Pretoria;
The Military hospital of Tunis; Tunis;
Department of Paediatrics - Alupe University College; Busia;
First Care Medical Centre; Soweto;
Mediclinic Sandton; Bryanston;
Maternal Adolescent and Child Health - School of Public Health University of Witwatersrand; Johannesburg; (MatCH Wits)
Empilweni TB Hospital; Port Elizabeth;
Centre Hospitalier Universitaire - Hopital Aristide Le Dantec; Dakar; (CHU)
Netcare St. Augustine Hospital; Durban;
Louis Pasteur Hospital; Pretoria;
University of Ghana; Accra;
Service de Medicine Interne - Hôpital la Rabta; Tunis;
Wilmed Park Hospital; Klerksdorp;
Melrose House; Cape Town;
Aminu Kano Teaching Hospital; Kano; (AKTH)
Kotopounga primary school; Natitingou;
Faculty of Physical Therapy - Pharos University; Alexandria;
Sanofi-Aventis Administrative Office; Midrand;
GVI Oncology Clinical Research Unit; Kraaifontein;
Iatros International; Bloemfontein;
Department of Paediatrics and Child Health; Panorama;
Urban Comprehensive Health Centre; Ile Ife;
Engelbrecht Research Limited; Centurion; (PTY)
Mekelle University; Mek'ele;
Clinical Projects Research; Worcester;
Sukuta Health Center; Brikama;
Allergology Diagnostic Clinical Research Centre; Western Cape; (ADCRU)
Joint Clinical Research Centre; Lubowa;
City Park Medical Centre; Cape Town;
Gatesville Medical Centre; Cape Town;
General Reference Hospital Mushie Hospital; Bandundu; (HGR)
Manor Medical Center; Sandton;
Cardiology Clinical Research; Alberton;
University of the Free State; Bloemfontein;
Department of Radiotherapy - Addington Hospital; Durban;
Steve Biko Academic Hospital - University of Pretoria; Pretoria;
Medi-clinic Panorama Heart and Lung Unit - Medi-Clinic Panorama; Parow;
Nelson Mandela Academic Clinical Research Unit - Nelson Mandela Academic Hospital; Mthatha;(NeMACRU)
Wits RHI Shandukani Research Centre CRS; Johannesburg; (RHI)
Africa Health Research Institute; Durban;
Hospital Charles Nicolle of Tunis; Tunis;
Mary Potter Oncology Centre; Pretoria;
Wellcome Centre for Infectious Diseases Research in Africa - University of Cape Town; Observatory;
Pediatric Department - Mansoura University Hospitals; Mansoura;
Boland Ethical Research Group; Western Cape;
Mbale Regional Referral Hospital; Mbale;
Global Clinical Trials; Pretoria;
Scion Clinical Research; Pretoria;
Cooper University Hospital Clinical Research Site; Durban;
Rahima Moosa Mother and Child Hospital; Johannesburg;
Western Cape Clinical Trials; Western Cape;
Flora Clinic; Roodepoort;
Southern Cross Hospital; Cape Town;
Enhancing Care Foundation; Durban;
Project San Francisco - Emory University; Kigali;
Poli Clinic; Port Elizabeth;
Clinical Research Center of Butembo - Catholic University of Graben; Butembo;
Cairo Hospital; Cairo;
Centre Hospitalier du Mont-Amba; Kinshasa;
Montana Hospital; West Coast;
Murtala Muhammad Specialist Hospital; Kano;
Kar Geno Center Kisumu Women Center For Hope; Kisumu;
Uganda Virus Research Institute - International AIDS Vaccine Initiative HIV Vaccine Program; Entebbe; (UVRI-IAVI CRS)
Deborah Retief Memorial Hospital; Mochudi;
Ifakara Health Institute; Dar es Salaam;
Abu Rish Children's Hospital; Cairo;
Practice Prof. Y Elhawary - AlSalama Hospital; Cairo;
South Medical Hospital; Chitungwiza;
New Specialist Outpatient Department; Cape Town;
Center for Clinical Care and Clinical Research; Abuja; (CCCRN)
University of Cape Coast; Cape Coast;
Mount Kenya University Trust; Thika; (MKU)
Clinical Research Center - Alexandria University hospital; Cairo;
School of Public Health Research Centre - University of Health and Allied Sciences; Ho Volta; (SPH UHAS)
Drs Gudgeon and Boeddinghaus Associates; Cape Town;
Intercare Tyger Valley Healthcare Centre; Bellville;
George Clinical Study Site; George;
University of Botswana/McMAsters University; Gaborone;
Consultorio Medico Esperanza; Chimoio;
Clinical Research Center - Air Force Specialized Hospital; Cairo;
Helderberg Clinical Research Centre; Somerset West;
Health Insurance Hospital; Cairo;
Meulmed Hospital; Pretoria;
PAREXEL Port Elizabeth; Port Elizabeth;
Department of Clinical Pharmacy and Pharmacy Management - Nnamdi Azikwe University; Awka;
Newlands Clinic; Harare;
St George's Medical Centre; Port Elizabeth;
JOSHA Research; Bloemfontein;
Kenyatta University Teaching Referral and Research Hospital; Kahawa West;
Pumwani Maternity Hospital; Nairobi;
Winelands Medical Research Centre; Cape Winelands;
Clinical Research Center - Faculty of Medicine Ain Shams University Research Institute; El Mohamady;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
Dr George Mukhari Academic Hospital; Ga-Rankuwa;
Genelin Clinical Trials; Free State;
Cosmos Medical Centre; Mpumalanga;
Centre Hospitalo-universitaire Bologhine Hospital; Algiers;
Department of Endocrinology - Old Main Building, Groote Schuur Hospital; Cape Town;
St. James's Hospital Life Health; East London;
Central Primary Health Centre; Akahia;
National Institute for Medical Research; Tanga;
St Mary's Clinical Research Site -The University of Zimbabwe College of Health Sciences Clinical Trials Research Centre; Harare; (UZCHS-CTRC)
Bondo Clinic - Bondo District Hospital; Bondo;
Dr Rory Callaghan Inc; Durban;
Africa University Clinical Research Centre; Mutare; (AUCRC)
Cooper Centre; Durban;
Paediatric Infectious Diseases Clinical Research Unit; Cape Town; (KID-CRU)
Medical Research Council Uganda Virus Research Institute Research Unit on AIDS; Entebbe;
Lung Infection And Immunity Unit - University of Cape Town; Cape Town;
Medicross Medical Centre Eldoraigne; Centurion;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Faculty of Medicine - Minia University; El Menia;
East Central Hospital; Windhoek;
Medpark; Cape Town;
Universite de Medecine et Science de la Sante; Dakar;
Investigator Clinic; Giza;
Noguchi Memorial Institute for Medical Research; Accra; (NMIMR)
Khayelitsha Clinical Research site; Khayelitsha;
University Of Lome; Lome;
Hospital Central de l'Armée; Algiers;
Tygerberg Hospital; Parrow;
Aswan Heart Center; Aswan;
Health and Wellness Clinic; Pretoria;
Society for Family Health Headquarters; Port Harcourt;
Thomo Clnic; Limpompo;
Khayelitsha Ekhayavac Clinic; Khayelitsha;
Scottish Livingstone Hospital; Molepolole;
Centre Hospitalo-Universitaire de Constantine; Constantine; (CHU)
Department of Internal Medicine - University of Cape Town; Cape Town;
Fairfield Medical Suites; Clairemont;
Respiratory and Meningeal Pathogens Research Unit; Soweto; (RMPRU)
Jackson F. Doe Memorial Hospital; Tapeta;
Hôpital d'enfants; Tunis;
Medical and Dental Centre; Randburg;
Hiway Medical Center; Durban;
Centre for Infectious Disease Research; Lusaka; (CIDRZ)
The Aga Khan University Hospital; Nairobi;
Instituto Nacional de Saúde; Maputo; (INS)
Botswana - University of Pennsylvania; Gaborone; (Upenn)
Medicross Bluff Medical Center; Durban;
Limbe Health Center; Sud-Ouest;
Blantyre Clinical Research Site; Blantyre; (CRS)
Johese Clinical Research; Centurion;
Netcare N1 City Hospital; Cape Town;
Ain Shams University; Cairo;
Helen Joseph Hospital; Johannesburg;
Walter Sisulu University HIV Vaccine Research Unit CRS; Mthatha;
Intercare Medical and Dental Centre; Lynwood;
Skin Avenue Clinic; El Salam El Sharkaia;
School of Medicine - Moi University; Eldoret;
Moriana Clinical Research; Free State;
Ndola District Health Management Board; Ndola;
Netcare Moot General Hospital; Pretoria;
Military Hospital; Accra;
Bertoni Mercy Clinic; Pretoria;
Beitbridge District Hospital; Beitbridge;
Gaborone Clinical Research Site; Gaborone;
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza;
Department of Paediatrics and Child Health - University of Ilorin Teaching Hospital; Ilorin;
Damien Foundation; Abuja;
Consortium for Health Research and Advanced Training - University of Nigeria; Enugu; (CHERAT)
Mont Amba Medical Center - University of Kinshasa; Lemba;
Mulanda Health Centre IV; Tororo;
Limpopo Clinical Research Initiative; Limpompo;
Medical School; Durban;
University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF)
Center for Integrated Health Programs; Abuja; (CIHP)
University of California San Francisco - Kenya Medical Research Institute; Kisumu; (UCSF-KEMRI)
Marondera Provincial Hospital; Harare;
Eastern Cape Oncology Center; Port Elizabeth;
|
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy. |
Interventional |
Phase 3
|
Respiratory Tract Infection
|
2020-06-17 |
2023-11-12 |
Pfizer |
No
|
| NCT01151189 |
|
|
Efficacy Against TB Disease, Safety, and Immunogenicity of MVA85A/AERAS-485 in HIV-Infected Adults (C-030-485) |
Interventional |
Phase 2
|
Tuberculosis,HIV Infections
|
2011-07-01 |
2014-09-01 |
Aeras |
No
|
| NCT01582763 |
MLI, TUN
|
University of Bamako; Bamako;
Hospital Militaire; Montfleury;
|
International Guillain-Barré Syndrome Outcome Study |
Observational |
|
Miller Fisher Syndrome,Guillain-Barré Syndrome
|
2012-05-01 |
2024-09-01 |
Erasmus Medical Center |
No
|
| NCT01673360 |
ZAF
|
The Urology Hospital; Pretoria;
|
Collection of Long Term Patient Outcomes Data Following Implantation of AMS Surgical Devices |
Observational |
|
Pelvic Organ Prolapse,Female Stress Incontinence
|
2012-09-01 |
2021-12-01 |
ASTORA Women's Health |
No
|
| NCT03637985 |
Egypt
|
Al-Azhar University; Cairo;
|
Effect of 12 Weeks of Resistive Exercises Versus Aerobic Exercises in Overweight Hypertensive Postmenopausal Women |
Interventional |
Not Applicable
|
Exercise
|
2017-09-01 |
2018-08-01 |
Cairo University |
No
|
| NCT04565184 |
ZAF
|
National District Hospital; Bloemfontein;
|
Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde |
Interventional |
Phase 4
|
Malaria,Falciparum
|
2019-05-09 |
2020-11-30 |
University of Yaounde 1 |
No
|
| NCT01218581 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
Aromatase Inhibitors or GnRH-a for Uterine Adenomyosis |
Interventional |
Phase 2,Phase 3
|
the Efficacy of Aromatase Inhibitor vs. Gonadotrpins Releasing Hormone Agonists in Treating Premenopausal Women With Uterine Adenomyosis
|
2005-12-01 |
2010-01-01 |
Mansoura University |
No
|
| NCT04558554 |
KEN
|
Walter Reed Project Clinical Research Center - Kenya Medical Research Institute; Nairobi; (WRP-KEMRI CRS)
Clinical Research Annexe - Kenya Medical Research Institute; Siaya; (KEMRI)
|
Pharmacy Delivery to Expand the Reach of PrEP in Kenya |
Interventional |
Not Applicable
|
HIV Prevention
|
2020-11-26 |
2021-11-01 |
University of Washington |
No
|
| NCT02265887 |
|
|
The Pan African Pulmonary Hypertension Cohort Study |
Observational |
|
Pulmonary Hypertension
|
2012-06-01 |
2015-06-01 |
University of Cape Town |
No
|
| NCT00074581 |
ZAF, BWA
|
Medicross Medical Centre Parow; Cape Town;
Gaborone Clinical Research Site; Gaborone;
|
Preventing Sexual Transmission of HIV With Anti-HIV Drugs |
Interventional |
Phase 3
|
HIV Infections
|
2005-02-01 |
2015-05-01 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT04196400 |
|
|
The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery. |
Interventional |
Early Phase 1
|
Hypospadias
|
2019-12-01 |
2021-03-01 |
Cairo University |
No
|
| NCT03443947 |
|
|
Modified Mallampati Scoring Technique for Airway Assessment |
Interventional |
Not Applicable
|
Intubation;Difficult
|
2018-03-01 |
2018-12-31 |
AlRefaey Kandeel |
No
|
| NCT00067522 |
ZMB
|
Zambia Emory HIV Research Project; Lusaka; (ZEHRP)
|
Preventing Unplanned Pregnancies in HIV Infected Zambian Couples |
Interventional |
Not Applicable
|
Pregnancy,HIV Infections
|
2002-01-01 |
|
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
No
|
| NCT04173819 |
ZAF
|
Reproductive Health and HIV Institute - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS RHI)
|
Safety and Pharmacokinetics of the Combination Broadly Neutralizing Antibodies, 3BNC117-LS-J and 10-1074-LS-J, in Healthy American and African Adults |
Interventional |
Phase 1,Phase 2
|
HIV-1-infection
|
2019-01-25 |
2021-12-01 |
International AIDS Vaccine Initiative |
No
|
| NCT01360008 |
ZAF
|
Medi-clinic Panorama; Parow;
Milpark Hospital; Johannesburg;
|
FREEZE Cohort Study |
Observational |
|
Arrhythmia
|
2011-04-01 |
2017-04-01 |
Stiftung Institut fuer Herzinfarktforschung |
No
|
| NCT02760888 |
EGY
|
Ain Shams University; Cairo;
|
Oral Tramadol Versus Diclofenac For Pain Relief Before Outpatient Hysteroscopy: |
Interventional |
Phase 3
|
Pain, Procedure
|
2016-05-01 |
2016-07-01 |
Ain Shams University |
No
|
| NCT04418310 |
|
|
Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease |
Interventional |
Not Applicable
|
Endoscopic Pilonidal Sinus
|
2020-06-12 |
2021-07-01 |
Mansoura University |
No
|
| NCT01435018 |
South Africa
|
University of Witwatersrand; Johannesburg;
|
Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS |
Interventional |
Phase 3
|
HIV-1 Infection
|
2013-10-01 |
2019-08-29 |
AIDS Clinical Trials Group |
No
|
| NCT04838587 |
ZAF
|
First Care Medical Centre; Soweto;
George Clinical Study Site; George;
|
An Epidemiological Surveillance Study to Determine the Incidence of ETEC in Children and Infants in Lusaka |
Observational |
|
Diarrhea Toddlers,Escherichia Coli Diarrhea
|
2020-10-15 |
2022-08-15 |
Centre for Infectious Disease Research in Zambia |
No
|
| NCT03980483 |
|
|
Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate |
Interventional |
Phase 3
|
Arthritis, Rheumatoid
|
2019-05-16 |
2022-11-11 |
GlaxoSmithKline |
No
|
| NCT01494987 |
ZAF
|
Paarl Research Centre; Paarl;
Helderberg Clinical Research Centre; Somerset West;
Tiervlei Trial Centre; Bellville; (TTC)
|
Ranolazine When Added to Glimepiride in Subjects With Type 2 Diabetes Mellitus |
Interventional |
Phase 3
|
Type 2 Diabetes Mellitus
|
2012-01-01 |
2013-08-01 |
Gilead Sciences |
No
|
| NCT02007005 |
EGY
|
Theodor Bilharz Research Institute; Giza; (TBRI)
|
Maximum Tolerable Concentration of abnobaVISCUM Fraxini Intravesically in Patients With Superficial Bladder Cancer |
Interventional |
Phase 1,Phase 2
|
Superficial Bladder Cancer
|
2004-01-01 |
2013-09-01 |
Abnoba Gmbh |
No
|
| NCT04141449 |
|
|
A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation |
Interventional |
Phase 2
|
Hiv,HNSCC,Neoplasms,Anal Cancer,Breast Cancer,Vulvar Cancer,Cancer Suspect,Cervical Cancer
|
2020-01-20 |
2024-09-19 |
Brigham and Women's Hospital |
No
|
| NCT04862975 |
BWA
|
Botswana - University of Pennsylvania; Gaborone; (Upenn)
|
Pharmacokinetic and Safety of Antiretroviral and Related Drugs in Lactating Women and Breastmilk Fed Infants |
Observational |
|
HIV Infections,Lactating Women on Select DOI,Breastmilk Fed Infants of Mothers on Select DOI
|
2021-10-28 |
2023-05-25 |
Duke University |
No
|
| NCT03772665 |
ZAF
|
Pretoria Eye Institute; Pretoria;
|
Safety and Efficacy of Emixustat in Stargardt Disease |
Interventional |
Phase 3
|
Stargardt Disease
|
2018-11-07 |
2022-06-01 |
Kubota Vision Inc. |
No
|
| NCT00380393 |
|
|
Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children. |
Interventional |
Phase 2
|
Malaria
|
2007-01-03 |
2008-11-11 |
GlaxoSmithKline |
No
|
| NCT00403962 |
|
|
A Combination Therapy In Patients With Social Anxiety Disorder |
Interventional |
Phase 2
|
Social Phobia
|
2004-11-01 |
2005-08-01 |
GlaxoSmithKline |
No
|
| NCT03890705 |
EGY
|
Assiut University; Assiut;
|
Postpartum Family Planning Utilization and Associated Factors Among Women During First Year After Childbirth in Assiut |
Observational |
|
Contraception
|
2019-06-01 |
2020-06-01 |
Assiut University |
No
|
| NCT00673842 |
ZAF
|
Netcare Unitas Hospital; Centurion;
Honeydew Medical Centre; Roodepoort;
|
Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction |
Interventional |
Phase 3
|
Sudden Death,Myocardial Infarction
|
2011-03-01 |
2021-12-01 |
University of Calgary |
No
|
| NCT03450798 |
EGY
|
Ain Shams University; Cairo;
|
SOFT Block Versus Spinal Anesthesia in Patientsusing Ilizarov External Fixator |
Interventional |
Not Applicable
|
Pain, Acute
|
2018-02-10 |
2019-01-10 |
Ain Shams University |
No
|
| NCT00386763 |
|
|
Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria. |
Interventional |
Phase 3
|
Malaria,Falciparum
|
2006-08-01 |
2007-03-01 |
Novartis |
No
|
| NCT03501524 |
EGY
|
Assiut University; Assiut;
|
VATS Evacuation Compared to Reinsertion of Thoracostomy Tube in Persistent Traumatic Haemothorax |
Interventional |
Not Applicable
|
Hemothorax; Traumatic
|
2017-07-01 |
2018-07-30 |
Assiut University |
No
|
| NCT04860284 |
EGY
|
Nasser Institute for Research and Treatment; Cairo;
|
Hydroxychloroquine for Treatment of Non-Severe COVID-19 |
Interventional |
Phase 2
|
Covid19
|
2020-09-18 |
2021-12-01 |
Makerere University |
Yes
|
| NCT03777358 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
Three-dimensional Ultrasonography Versus Hysteroscopy in Evaluation of Uterine Cavity in Infertile Women |
Observational |
|
Female Infertility
|
2019-01-01 |
2021-01-01 |
Hatem AbuHashim |
No
|
| NCT03337724 |
ZAF
|
Langenhoven Drive Oncology Centre; Port Elizabeth;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
|
A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer |
Interventional |
Phase 2,Phase 3
|
Breast Cancer
|
2018-01-06 |
2021-12-22 |
Hoffmann-La Roche |
No
|
| NCT02293460 |
TUN
|
Hopital Militaire; Tunis;
|
Efficacy and Safety Study of I10E in Treatment of Patients With CIDP |
Interventional |
Phase 3
|
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
|
2015-05-01 |
2017-09-29 |
Laboratoire français de Fractionnement et de Biotechnologies |
No
|
| NCT04372693 |
|
|
Unplanned Shifting to Online Distance Learning: Nursing Students' Perception and Achievement |
Interventional |
Not Applicable
|
Distance Learning-Online Learning,Traditional Classroom-Based Learning,Nursing Students' Perception and Achievement,Coronavirus Disease Social Distancing Measures
|
2020-02-01 |
2020-06-30 |
Kasr El Aini Hospital |
No
|
| NCT02531529 |
|
|
Dexmedetomedine Infusion Versus Fentanyl Infusion for Donor Anlgesia During Living Donor Hepatectomy |
Interventional |
Not Applicable
|
Donor Hepatectomy
|
2014-01-01 |
2015-04-01 |
Mansoura University |
No
|
| NCT04000009 |
ZAF
|
Scion Clinical Research; Pretoria;
|
Extension Study of Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment |
Interventional |
Phase 3
|
Adjunctive Treatment of Major Depressive Disorder
|
2019-06-03 |
2021-02-22 |
ACADIA Pharmaceuticals Inc. |
No
|
| NCT03864419 |
ZAF
|
Hopelands Cancer Centre; Durban;
|
Rituximab Hyaluronidase in Combination With Chemotherapy in Treating Aggressive B-cell Lymphoma in Uganda |
Interventional |
Phase 1
|
Burkitt Lymphoma,Diffuse Large B-Cell Lymphoma,KSHV-associated Multicentric Castleman Disease
|
2019-10-24 |
2023-05-04 |
Fred Hutchinson Cancer Research Center |
No
|
| NCT01001741 |
BWA
|
Independence Surgery; Gaborone;
|
Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana |
Interventional |
Not Applicable
|
HIV Infections
|
2008-06-01 |
2009-08-01 |
University of Pennsylvania |
No
|
| NCT03944317 |
NGA
|
Federal Medical Center; Owo; (FMCOWO)
|
Azithromycin (AZ) and Sulphadoxine-pyrimethamine (SP) for Malaria Prevention in Pregnant Women (IPT-AZ/IPT-SP) |
Interventional |
Not Applicable
|
Pregnancy,Malaria in Pregnancy
|
2019-06-01 |
2020-01-31 |
Federal Medical Centre, Owo |
No
|
| NCT03997019 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Erector Spinae Plane Block in Cardiac Surgery |
Interventional |
Not Applicable
|
Pain, Acute
|
2019-02-15 |
2020-12-15 |
Assiut University |
No
|
| NCT03273348 |
EGY
|
Assiut University; Assiut;
|
Role of Oncoplastic Breast Surgery In Breast Cancer Treatement |
Interventional |
Not Applicable
|
Breast Cancer
|
2017-09-28 |
2019-10-28 |
Assiut University |
No
|
| NCT02414308 |
ZAF
|
Mamma Clinic; Cape Town;
|
Management of Peyronie's Disease With Adipose Tissue Stem Cell |
Interventional |
Not Applicable
|
Peyronie' Disease,Erectile Dysfunction
|
2013-06-01 |
2016-07-01 |
Man Clinic for Andrology, Male Infertility and Sexual Dysfunction |
No
|
| NCT04336085 |
ZAF
|
Tara Hospital; Cape Town;
|
Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery |
Interventional |
Not Applicable
|
Post Operative Pain After Pediatric Hip Surgery
|
2020-05-15 |
2021-05-31 |
Tanta University |
No
|
| NCT03027258 |
NGA
|
Catholic Caritas Foundation; Abuja;
|
Point-of-Delivery Prenatal Test Results Through mHealth to Improve Birth Outcome |
Interventional |
Not Applicable
|
HIV,Hepatitis B,Sickle Cell Disease
|
2016-09-01 |
2018-01-01 |
University of Nevada, Las Vegas |
No
|
| NCT04479280 |
EGY
|
Assiut University; Assiut;
|
Evaluation of Coagulopathy in Critically Ill COVID-19 Patients. |
Observational |
|
Coagulation Disorder
|
2020-07-20 |
2020-08-01 |
Assiut University |
Yes
|
| NCT00002914 |
ZAF
|
Pretoria Academic Hospital; Pretoria;
|
Piritrexim in Treating Patients With Advanced Cancer of the Urinary Tract |
Interventional |
Phase 2
|
Bladder Cancer,Urethral Cancer,Transitional Cell Cancer of the Renal Pelvis and Ureter
|
1997-05-01 |
2004-03-01 |
Eastern Cooperative Oncology Group |
No
|
| NCT02281526 |
ZAF
|
Farmovs Intergrated Research Solutions; Bloemfontein;
|
An Open-label, Multiple-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093 |
Interventional |
Phase 1
|
Epilepsy
|
2005-05-01 |
2006-02-01 |
Bial - Portela C S.A. |
No
|
| NCT02497989 |
KEN
|
Impact Research and Development Organization; Kisumu; (IRDO)
|
Evaluating Demand Creation Strategies for Voluntary Medical Male Circumcision (VMMC) in Kenya |
Interventional |
Not Applicable
|
HIV/AIDS
|
2015-02-01 |
2016-01-22 |
Impact Research & Development Organization |
No
|
| NCT04102293 |
EGY
|
Ain Shams University; Cairo;
|
"Clinical and CBCT Evaluation of the Quality of Obturation and Time Efficiency of Rotary Versus Manual Instrumentation in Pediatric Endodontics" |
Interventional |
Not Applicable
|
Endodontic Disease
|
2019-09-01 |
2022-01-01 |
Reem Mahmoud Abdelkader Awad |
No
|
| NCT03253315 |
EGY
|
Assiut University; Assiut;
|
Management of Pericarditis in Children. |
Observational |
|
Pericarditis
|
2017-09-01 |
2019-04-01 |
Assiut University |
No
|
| NCT00317122 |
|
|
Assess the Immune Response Following Primary Vaccination With GSK Biologicals' Tritanrix™-HepB/Hib-MenAC vs Tritanrix™-HepB/Hiberix™ Given at 6,10 & 14 Wks of Age to Infants Who Received Hepatitis B Vaccine at Birth |
Interventional |
Phase 3
|
Diphtheria; Haemophilus Influenzae Type b; Hepatitis B; Tetanus; Whole Cell Pertussis
|
2004-10-01 |
2005-07-01 |
GlaxoSmithKline |
No
|
| NCT00004179 |
ZAF
|
Mary Potter Oncology Centre; Pretoria;
|
Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma |
Interventional |
Phase 3
|
Lymphoma
|
1999-05-01 |
2017-07-19 |
European Organisation for Research and Treatment of Cancer - EORTC |
No
|
| NCT00838903 |
|
|
Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes |
Interventional |
Phase 3
|
Diabetes Mellitus, Type 2
|
2009-02-01 |
2013-04-01 |
GlaxoSmithKline |
No
|
| PACTR202008842095447 |
EGY
|
Faculty of Physical Therapy - Pharos University; Alexandria;
|
Integrated neuromuscular inhibition for neck pain |
RCT |
|
Musculoskeletal Diseases,Orthopaedics
|
20-04-08 |
20-04-10 |
aliaa elabd |
No
|
| NCT00217737 |
ZAF, KEN
|
RK Khan Hospital; Chatsworth;
Netcare Unitas Hospital; Centurion;
Kisumu County Hospital; Kisumu;
Universitas Hospital; Bloemfontein;
|
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer |
Interventional |
Phase 3
|
Lynch Syndrome,Colon Mucinous Adenocarcinoma,Stage IIA Colon Cancer AJCC v7,Stage IIB Colon Cancer AJCC v7,Stage IIC Colon Cancer AJCC v7,Colon Signet Ring Cell Adenocarcinoma
|
2005-08-04 |
|
National Cancer Institute (NCI) |
No
|
| NCT04767139 |
GHA
|
Greater Accra Regional Hospital; Accra; (RIDGE)
|
EPI, a Missed Opportunity for Postpartum Family Planning Utilization |
Observational |
|
Contraception
|
2020-02-01 |
2021-02-28 |
Hawassa University |
No
|
| NCT04038060 |
ZAF
|
Reproductive Health and HIV Institute - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS RHI)
|
The PrEP (Pre-exposure Prophylaxis) SMART Study |
Interventional |
Phase 4
|
HIV/AIDS
|
2019-05-16 |
2022-07-01 |
University of Washington |
No
|
| NCT03514459 |
ZWE
|
Spilhaus Clinical Research Site - Zimbabwe National Family Planning Council Clinic; Harare; (ZNFPC CRS)
|
Testing an Implementation Science Tool to Increase Cervical Cancer Screening in Mombasa, Kenya |
Interventional |
Not Applicable
|
Cervical Cancer
|
2020-01-29 |
2021-07-01 |
University of Washington |
No
|
| NCT02446132 |
ZAF
|
Cape Trial Centre; Bellville;
Apollo Clinical Research; Johannesburg;
|
Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type |
Interventional |
Phase 3
|
Agitation in Patients With Dementia of the Alzheimer's Type
|
2015-12-01 |
2023-10-01 |
Avanir Pharmaceuticals |
No
|
| NCT00003881 |
ZAF
|
Pretoria Academic Hospital; Pretoria;
|
Trastuzumab Plus Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer |
Interventional |
Phase 2
|
Lung Cancer
|
1999-05-01 |
2004-07-01 |
Eastern Cooperative Oncology Group |
No
|
| NCT04384614 |
TUN
|
Eshmoun Clinical Research Centre; Tunis;
|
Covid-19 In Tunisia: An Observational Cross-Sectional Registry Study |
Observational |
|
Covid 19,BCG Vaccination
|
2020-05-15 |
2020-07-15 |
Direction des Soins de Santé de Base |
Yes
|
| NCT02580344 |
EGY
|
Assiut University; Assiut;
|
The Effect of Ibuprofen on Intrauterine Contraceptive Device Associated Uterine Bleeding |
Interventional |
Phase 2
|
Contraception
|
2015-10-01 |
2016-11-01 |
Assiut University |
No
|
| NCT02421302 |
Uganda, ZAF
|
Infectious Diseases Institute; Kampala; (IDI)
Africa International Research; Cape Town;
|
The Pediatric HIV Nutrition Study in Uganda |
Interventional |
Not Applicable
|
Child Nutrition Disorders
|
2015-02-01 |
2016-04-01 |
Infectious Diseases Institute |
No
|
| NCT04263116 |
|
|
Balloon-Assisted Maturation of Autogenous Arteriovenous Fistulae |
Interventional |
Not Applicable
|
Hemodialysis Access Failure
|
2017-07-25 |
2019-05-30 |
Mansoura University |
No
|
| NCT01023789 |
EGY, ZAF
|
Cairo Hospital; Cairo;
Netcare Moot General Hospital; Pretoria;
|
ABSORB EXTEND Clinical Investigation |
Interventional |
Not Applicable
|
Coronary Disease,Coronary Restenosis,Myocardial Ischemia,Cardiovascular Disease,Coronary Artery Disease,Coronary Artery Stenosis
|
2010-01-01 |
2016-10-01 |
Abbott Medical Devices |
No
|
| NCT04781257 |
ZWE, MOZ, TZA
|
Biomedical Research and Training Institute; Harare; (BRTI)
Centro de Investigação em Saúde de Manhiça; Mopeia; (CISM)
National Institute for Medical Research - Mbeya Medical Research Center; Mbeya; (MMRC NIMR)
|
Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries |
Observational |
|
Tuberculosis
|
2021-03-01 |
2023-12-01 |
Michael Hoelscher |
No
|
| NCT03887975 |
EGY
|
Ain Shams University; Cairo;
|
T-Scan Study of Occlusion in Case of Implant Retained Overdenture |
Interventional |
Not Applicable
|
Edentulous Alveolar Ridge,Dental Occlusion, Traumatic
|
2018-02-20 |
2019-02-01 |
Ain Shams University |
No
|
| NCT00116298 |
TZA
|
National Institute for Medical Research; Tanga;
|
Rollover Study for Zerit (Stavudine) ER Studies (-096, -099) |
Interventional |
Phase 3
|
AIDS,HIV Infections
|
2001-01-01 |
2005-01-01 |
Bristol-Myers Squibb |
No
|
| NCT04431726 |
KEN, ZAF, MOZ, South Africa, AGO, TUN, Uganda, EGY, NGA, GIN, UGA
|
Department of Paediatrics - Alupe University College; Busia;
Charlotte Maxeke Johannesburg Academic Hospital; Johannesburg;
Louis Pasteur Hospital; Pretoria;
Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS)
Centro de Investigação em Saúde de Manhiça; Mopeia; (CISM)
Department of Haematology and Cell Biology - University of the Free State; Bloemfontein;
HIV Clinical Research Unit - Wits University; Johannesburg ; (CHRU)
Instituto de Combate e Controlo das Tripanossomiases; Luanda; (ICCT)
Manor Medical Center; Sandton;
Arthritis Clinical Research Trials; Cape Town;
Service Haematologie - Hopital Militaire de Tunis; Tunis;
Mbale Regional Referral Hospital; Mbale;
Paediatric Hospital - Cairo University; Cairo;
Abu Rish Children's Hospital; Cairo;
PAREXEL Port Elizabeth; Port Elizabeth;
Department of Medical Microbiology Parasitology - College of Medicine University of Ibadan; Oyo;
Laboratoire Des Fièvres Hémorragiques Guinea; Conakry;
St. James's Hospital Life Health; East London;
Amudat Hospital; Amudat;
Pretoria Academic Hospital; Pretoria;
Rheumatology Department Faculty of Medicine - Ain Shams University; El Mohamady;
Service de Rhumatologie-Hôpital La Rabta; Sfax;
Red Cross Children's Hospital - University of Cape Town; Cape Town;
|
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors |
Interventional |
Phase 3
|
Severe Hemophilia A
|
2021-02-04 |
2029-12-16 |
Hoffmann-La Roche |
No
|
| NCT02573324 |
ZAF
|
University of Cape Town; Cape Town;
|
A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification |
Interventional |
Phase 2,Phase 3
|
Gliosarcoma,Glioblastoma
|
2015-12-07 |
2021-12-31 |
AbbVie |
No
|
| NCT03295487 |
|
|
ToT and Estrogen in Postmenopausal Females |
Interventional |
Phase 2,Phase 3
|
Postmenopausal Disorder,Stress Urinary Incontinence
|
2017-03-01 |
2017-09-30 |
Kasr El Aini Hospital |
No
|
| NCT04721964 |
ETH
|
Hawassa University Referral Hospital; Awassa;
|
Evaluation of the Effects of Routine Iron Supplementation in Children on Gastrointestinal Iron Losses |
Interventional |
Not Applicable
|
Iron-deficiency,Iron Deficiency Anemia,Gastro Intestinal Bleeding
|
2021-02-25 |
2021-12-01 |
Swiss Federal Institute of Technology |
No
|
| NCT03413579 |
MOZ
|
Centro de Investigação em Saúde de Manhiça; Mopeia; (CISM)
|
Evaluate Efficacy of the Association Nimotuzumab(HR3) /Cisplatin-Vinorelbine on Patients With Cervical Carcinom |
Interventional |
Phase 3
|
Cervical Cancer
|
2015-11-01 |
2021-12-01 |
El Kendi Pharmaceuticals Manufacturing Company |
No
|
| NCT03893097 |
SEN
|
Institut De Recherche En Santé De Surveillance Épidémiologique Et De Formation; Rufisque; (IRESSEF)
|
Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children |
Interventional |
Phase 3
|
Schistosoma Mansoni,Schistosoma Haematobium
|
2019-10-14 |
2021-03-04 |
Institute of Tropical Medicine, Belgium |
No
|
| NCT00123474 |
EGY, KEN, ZAF, NGA, SEN, BWA, MWI, TZA, Togo, GHA, Malawi, UGA
|
Clinical Research Center - Cairo University; Giza;
International Cancer Institute; Uasin Gishu;
Department of Medicine - University of Cape Town; Cape Town;
Hopelands Cancer Centre; Durban;
Manor Medical Center; Sandton;
Department of Radiotherapy - Addington Hospital; Durban;
Africa Health Research Institute; Durban;
College of Medicine - University of Lagos; Lagos;
Mary Potter Oncology Centre; Pretoria;
Boland Ethical Research Group; Western Cape;
Niakhar Demographic Surveillance System; Dakar;(DS IDR)
Western Cape Clinical Trials; Western Cape;
Department of Paediatrics - University of Calabar; Calabar;
Flora Clinic; Roodepoort;
New Pretoria Academic Hospital; Pretoria;
Murtala Muhammad Specialist Hospital; Kano;
George Clinical Study Site; George;
University of Botswana/McMAsters University; Gaborone;
University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC)
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
National Institute for Medical Research; Tanga;
University Of Lome; Lome;
University Of Health And Allied Sciences; Ho Volta Region;
Botswana - University of Pennsylvania; Gaborone; (Upenn)
Cancer Centre - Tanta University; Tanta;
School of Medicine - Moi University; Eldoret;
College of Medicine - University of Malawi; Blantyre;
Damien Foundation; Abuja;
Mont Amba Medical Center - University of Kinshasa; Lemba;
|
Chronic Myelogenous Leukemia (CML) - Follow on: Study of BMS-354825 in Subjects With CML |
Interventional |
Phase 3
|
Myeloid Leukemia, Chronic, Chronic-Phase
|
2005-07-01 |
2014-07-01 |
Bristol-Myers Squibb |
No
|
| NCT04598165 |
GMB, KEN
|
Sukuta Health Center; Brikama;
Kisumu County Hospital; Kisumu;
Bondo Clinic - Bondo District Hospital; Bondo;
Mathare North City Clinic; Nairobi;
|
Mobile WACh NEO: Mobile Solutions for Neonatal Health and Maternal Support |
Interventional |
Not Applicable
|
Depression,Neonatal Death,Perinatal Death
|
2020-09-07 |
2023-05-30 |
University of Washington |
No
|
| NCT04475809 |
EGY
|
Faculty of Medicine - Zagazig University; Zagazig;
|
Different Maneuvers for Reducing Post-laparoscopic Pain |
Interventional |
Not Applicable
|
Gynecologic Disease
|
2020-07-13 |
2020-12-01 |
Zagazig University |
No
|
| PACTR202007606032743 |
EGY
|
15th of May Hospital; Cairo;
|
Nebulized heparin in patients with mainly moderate coronavirus disease 2019: Randomized controlled trial. COVID-19 |
RCT |
|
Infections and Infestations
|
70-01-01 |
70-01-01 |
Dr Tarek Ismail |
Yes
|
| NCT04516811 |
ZMB, ZAF
|
St Pauls Mission Hospital; Nchelenge;
Universitas Hospital; Bloemfontein;
|
Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19 |
Interventional |
Phase 3
|
COVID-19,SARS-CoV-2 Infection,Severe Acute Respiratory Syndrome Coronavirus 2
|
2020-09-21 |
2022-07-31 |
South African National Blood Service |
Yes
|
| NCT02145468 |
|
|
A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60) |
Interventional |
Phase 3
|
Acute Coronary Syndrome
|
2014-06-03 |
2015-12-14 |
GlaxoSmithKline |
No
|
| NCT02994030 |
EGY
|
Ain Shams University; Cairo;
|
Biomarker for Duchenne Muscular Dystrophy |
Observational |
|
Lordosis,Scoliosis,Hyporeflexia,Muscular Atrophy,Muscular Weakness,Red-Green Color Blindness,Duchenne Muscular Dystrophy,Increased Lordosis/Scoliosis
|
2018-08-20 |
2023-12-01 |
Centogene AG Rostock |
No
|
| NCT04338321 |
DZA
|
Centre Hospitalo-Universitaire d'Oran; Oran; (CHU)
|
A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder |
Interventional |
Phase 3
|
Depressive Disorder, Major
|
2020-08-21 |
2022-12-15 |
Janssen-Cilag International NV |
No
|
| NCT00553410 |
ZAF
|
Tygerberg Hospital; Parrow;
|
Letrozole in Preventing Cancer in Postmenopausal Women Who Have Received 4-6 Years of Hormone Therapy for Hormone Receptor-Positive, Lymph Node-Positive, Early-Stage Breast Cancer |
Interventional |
Phase 3
|
Breast Cancer
|
2007-08-01 |
2019-05-15 |
International Breast Cancer Study Group |
No
|
| NCT01899742 |
|
|
The Purpose of the This Study is to Evaluate the Spirometric Effect (Trough FEV1) of Umeclidinium/Vilanterol 62.5/25 mcg Once Daily Compared With Tiotropium 18mcg Once Daily Over a a 12-week Treatment Period in Subjects With COPD Who Continue to Have Symptoms on Tiotropium |
Interventional |
Phase 3
|
Pulmonary Disease, Chronic Obstructive
|
2014-09-15 |
2015-07-22 |
GlaxoSmithKline |
No
|
| NCT01123551 |
TUN
|
Fottouma Bourguiba University Hospital; Monastir;
|
Efficacy Study of Nebulized Morphine and Intravenous Morphine in Post Traumatic Pain |
Interventional |
Phase 3
|
Post Traumatic Pain
|
2010-06-01 |
2014-07-01 |
University of Monastir |
No
|
| NCT00003808 |
ZAF
|
Pretoria Academic Hospital; Pretoria;
|
Theophylline in Treating Patients With In Situ, Stage I, or Stage II Chronic Lymphocytic Leukemia |
Interventional |
Phase 2
|
Leukemia
|
1999-05-01 |
|
Eastern Cooperative Oncology Group |
No
|
| NCT00002823 |
BDI, ZAF
|
Institut National d'Oncologie; Bujumbura;
Universitas Hospital; Bloemfontein;
|
Combination Chemotherapy Compared With No Treatment Following Surgery in Treating Patients With Non-small Cell Lung Cancer |
Interventional |
Phase 3
|
Lung Cancer
|
1995-02-01 |
|
Gustave Roussy, Cancer Campus, Grand Paris |
No
|
| NCT03799055 |
EGY
|
Banha University Hospital; Qalyoubia;
|
Ultrasonography vs Conventional Methods for Prediction of Difficult Airway in Adult Patients |
Observational |
|
Difficult Intubation
|
2019-06-10 |
2020-01-10 |
Benha University |
No
|
| NCT00676143 |
ZAF
|
Netcare St. Augustine Hospital; Durban;
|
Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients |
Interventional |
Phase 3
|
Alzheimer Disease
|
2008-01-01 |
2012-11-01 |
Pfizer |
No
|
| NCT03047642 |
MOZ
|
Instituto Nacional de Saúde; Maputo; (INS)
|
Validation of Promising Biomarker Assays to Assess Their Diagnostic Performance Characteristics |
Observational |
|
Acute Febrile Illnesses
|
2017-04-27 |
2019-11-27 |
Foundation for Innovative New Diagnostics, Switzerland |
No
|
| NCT00980538 |
South Africa, ZAF
|
JOSHA Research; Bloemfontein;
Farmovs Intergrated Research Solutions; Bloemfontein;
Excellentis Clinical Trial Consultants; George;
Synapta Clinical Research Centre; Durban;
|
TMC125-TiDP35-C239 - Continued Access to Etravirine (ETR) in Treatment Experienced HIV-1 Infected Participants |
Interventional |
Phase 3
|
HIV-1,HIV Infections
|
2009-12-01 |
2024-01-01 |
Janssen Sciences Ireland UC |
No
|
| NCT02362503 |
|
|
Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients |
Interventional |
Phase 3
|
HIV Infections
|
2015-02-23 |
2024-12-31 |
ViiV Healthcare |
No
|
| NCT03700749 |
NGA
|
Lagos University Teaching Hospital; Idi Araba;
|
FALCON Trial Testing Measures to Reduce Surgical Site Infection |
Interventional |
Phase 3
|
Abdominal Surgery,Surgical Site Infection
|
2018-11-29 |
2021-07-31 |
University of Birmingham |
No
|
| NCT04316871 |
EGY
|
Assiut University; Assiut;
|
Dosage of Epidural Morphine in Elderly Patients |
Interventional |
Phase 4
|
Age Problem,Abdominal Cancer
|
2020-03-20 |
2021-06-30 |
Assiut University |
No
|
| NCT03477136 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Serum and Semen Vitamin D Level With Semen Parameters |
Observational |
|
Vitamin D Deficiency
|
2018-12-06 |
2021-04-01 |
Assiut University |
No
|
| NCT04048018 |
COD, ZMB, ZAF, EGY, UGA, KEN, Sierra Leone, BWA, CMR, DZA, NGA, TZA, ZWE
|
General Reference Hospital Masi Manimba Hospital; Bandundu; (HGR)
Choma District Health Office; Choma;
Louis Pasteur Hospital; Pretoria;
General Reference Hospital Mushie Hospital; Bandundu; (HGR)
University of the Free State; Bloemfontein;
Flora Clinic; Roodepoort;
Abu Rish Children's Hospital; Cairo;
Omugo Health Centre IV; Terego;
University of Nairobi College of Health Sciences - Kenyatta National Hospital; Nairobi; (KNH UON)
TUBERCULOSIS RESEARCH; Freetown;
University of Botswana/McMAsters University; Gaborone;
Douala General Hospital; Douala;
Centre Hospitalo-universitaire Bologhine Hospital; Algiers;
Lung Infection And Immunity Unit - University of Cape Town; Cape Town;
Hospital Central de l'Armée; Algiers;
Centre Anti-Cancer; Annaba;
Moriana Clinical Research; Free State;
Department of Paediatrics and Child Health - University of Ilorin Teaching Hospital; Ilorin;
Mwanza Intervention Trials Unit - Tanzania National Institute for Medical Research and the London School of Hygiene and Tropical Medicine; Mwanza; (NIMR LSHTM)
University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF)
|
Performance Evaluation of the VIDAS TB-IGRA Assay. |
Observational |
|
Active Tuberculosis,Latent Tuberculosis Infection,Non-Tuberculous Mycobacterial (NTM) Pneumonia
|
2019-12-05 |
2021-06-30 |
BioMérieux |
No
|
| NCT02728232 |
|
|
Internal Iliac Artery Ligation and Abnormally Invasive Placenta |
Interventional |
Not Applicable
|
Placenta Percreta
|
2016-04-01 |
2017-04-01 |
Cairo University |
No
|
| NCT01215747 |
ZAF, TUN
|
RK Khan Hospital; Chatsworth;
La Rabta hospital Tunis; Tunis;
Fottouma Bourguiba University Hospital; Monastir;
|
Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis |
Interventional |
Phase 3
|
Amyloidosis
|
2010-11-01 |
2016-03-01 |
C.T. Development America, Inc. |
No
|
| NCT03657316 |
EGY
|
Assiut University; Assiut;
|
Impact of School Based Education Program |
Interventional |
Not Applicable
|
Diet Modification
|
2019-09-01 |
2021-12-01 |
Assiut University |
No
|
| NCT04240938 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Adult Dacryocystocele Among Patients With Epiphora |
Interventional |
Not Applicable
|
Lacrimal Passage Obstruction
|
2017-03-01 |
2019-12-30 |
Minia University |
No
|
| NCT02269943 |
TUN
|
Salah Azaiez Institute; Tunis;
|
Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal Carcinoma |
Interventional |
Phase 2
|
Nasopharyngeal Neoplasms
|
2015-02-13 |
2017-04-20 |
Celgene |
No
|
| NCT00084318 |
EGY, GHA, COD, BWA, DZA, ZAF, KEN, MAR, NGA, Uganda, SEN, BEN, BFA, ZWE, ETH, MWI, ZMB, UGA, TUN, CMR, Ghana, Togo, LBR
|
Clinical Research Center - Cairo University; Giza;
Greater Accra Regional Hospital; Accra; (RIDGE)
General Reference Hospital Masi Manimba Hospital; Bandundu; (HGR)
Francistown Academic Hospital; Francistown;
Al Mouneer Diabetic Retina Center; Giza;
Etablissement Hospitalo-Universitaire Oran; Oran;
Wilgers Medical Consortium; Pretoria;
International Cancer Institute; Uasin Gishu;
Clintrial Consultants; Cape Town;
Molepolole BHP Study Clinic - Scottish Livingstone Hospital; Molepolole;
Mediclinic Sandton; Bryanston;
Louis Pasteur Hospital; Pretoria;
Netcare Greenacres Hospital; Port Elizabeth;
Specialty Hospital of Rabat; Rabat ;
Urban Comprehensive Health Centre; Ile Ife;
Hopelands Cancer Centre; Durban;
Manor Medical Center; Sandton;
Vaal Triangle Oncology - Clinical and Radiation Oncologists A.B.J. Inc; Vereeniging;
Mary Potter Oncology Centre; Pretoria;
Mbale Regional Referral Hospital; Mbale;
Mainland Hospital Yaba; Yaba;
Cooper University Hospital Clinical Research Site; Durban;
Hospital General De Grand Yoff; Dakar;
Southern Cross Hospital; Cape Town;
Centre de Pneumo-Phtisiologie d'Akron; Akron;
Clinical research Unit of Nanoro - Saint Camille Medical Center of Nanoro; Ouagadougou; (CRUD - CMA)
Richards Bay Trial Center - Bay Hospital; KwaZulu Natal;
Deborah Retief Memorial Hospital; Mochudi;
Abu Rish Children's Hospital; Cairo;
South Medical Hospital; Chitungwiza;
Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region;
Clinical Research Center - Alexandria University hospital; Cairo;
Kuils river Hospital; Kuils River;
Drs Gudgeon and Boeddinghaus Associates; Cape Town;
Faculty of Health Sciences - University of Cape Town; Cape Town; (UCT)
Clinical Research Center - Agaro General Hospital; Agaro; (CRC)
Intercare Tyger Valley Healthcare Centre; Bellville;
Centre Pierre-et-Marie-Curie; Sidi M'Hamed; (CPMC)
Meulmed Hospital; Pretoria;
PAREXEL Port Elizabeth; Port Elizabeth;
University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC)
St Pauls Mission Hospital; Nchelenge;
St George's Medical Centre; Port Elizabeth;
The College; Cape Town;
Clinical Research Center - Faculty of Medicine Ain Shams University Research Institute; El Mohamady;
Department of Radiation Oncology - University of Cape Town; Cape Town;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
N1 City Mews; Cape Town;
Masaka Medical Research Council - Uganda Virus Research Institute; Entebbe;
Sandton Oncology Cancer Centre; Sandton;
Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH)
Health Services Department - University of Benin; Benin;
Centre anti-cancer d'Oran; Oran;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Care and Health Program; Yaounde;
Noguchi Memorial Institute for Medical Research; Accra; (NMIMR)
University Of Lome; Lome;
Honeydew Medical Centre; Roodepoort;
University Of Health And Allied Sciences; Ho Volta Region;
Scottish Livingstone Hospital; Molepolole;
Nasser Institute for Research and Treatment; Cairo;
Centre Anti-Cancer; Annaba;
Jackson F. Doe Memorial Hospital; Tapeta;
Service de Rhumatologie - Hospital Charles Nicolle of Tunis; Tunis;
Medical and Dental Centre; Randburg;
South Valley University; Qena;
Hiway Medical Center; Durban;
Kimberley Hospital Complex; Kimberley;
Medicross Bluff Medical Center; Durban;
Cancer Centre - Tanta University; Tanta;
Helen Joseph Hospital; Johannesburg;
Intercare Medical and Dental Centre; Lynwood;
Netcare Moot General Hospital; Pretoria;
Bertoni Mercy Clinic; Pretoria;
Medical School; Durban;
University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF)
Nelson Mandela Academic Hospital - Mthatha Hospital Complex; Eastern Cape;
Bishop Lavis Day Hospital; Cape Town;
Watany Research and Development Center - Watany Eye Hospital; Cairo; (WEH)
|
Adjuvant Cetuximab and Chemoradiotherapy Using Either Cisplatin or Docetaxel in Treating Patients With Resected Stage III or Stage IV Squamous Cell Carcinoma or Lymphoepithelioma of the Head and Neck |
Interventional |
Phase 2
|
Head and Neck Cancer
|
2004-04-01 |
2016-12-01 |
Radiation Therapy Oncology Group |
No
|
| NCT03411928 |
|
|
Endotracheal Dilator to Improve Oxygenation |
Interventional |
Not Applicable
|
Airway Disease,Tracheal Stenosis,Pediatric Respiratory Diseases
|
2018-09-01 |
2018-12-30 |
University of Cape Town |
No
|
| NCT00002632 |
ZAF
|
Pretoria Academic Hospital; Pretoria;
|
Paclitaxel in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer |
Interventional |
Phase 2
|
Head and Neck Cancer
|
1995-03-01 |
|
Eastern Cooperative Oncology Group |
No
|
| NCT00819156 |
ZAF
|
Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS)
The Urology Hospital; Pretoria;
|
Dose Finding Trial With a New Treatment (Degarelix) for Prostate Cancer |
Interventional |
Phase 2
|
Prostate Cancer
|
2004-02-01 |
2005-09-01 |
Ferring Pharmaceuticals |
No
|
| NCT03601806 |
TZA, KEN
|
Bugando medical Centre; Mwanza;
School of Medicine - Moi University; Eldoret;
|
Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection |
Interventional |
Phase 2
|
Skin Kaposi Sarcoma,Human Immunodeficiency Virus 1 Positive
|
2021-04-26 |
2023-10-30 |
AIDS Malignancy Consortium |
No
|
| NCT02206451 |
|
|
Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Mali |
Observational |
|
Malaria
|
2014-07-16 |
2014-07-16 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT00562965 |
|
|
Study Comparing Inotuzumab Ozogamicin In Combination With Rituximab Versus Defined Investigator's Choice In Follicular Non-Hodgkin's Lymphoma (NHL) |
Interventional |
Phase 3
|
Lymphoma, Follicular
|
2007-11-01 |
2011-04-01 |
Pfizer |
No
|
| NCT02105974 |
|
|
Study Evaluating the Efficacy and Safety of Fluticasone Furoate/Vilanterol Inhalation Powder (FF/VI) Compared With Vilanterol Inhalation Powder (VI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD) |
Interventional |
Phase 3
|
Pulmonary Disease, Chronic Obstructive
|
2014-04-07 |
2015-07-08 |
GlaxoSmithKline |
No
|
| NCT04319380 |
BFA
|
Institut de Rechererch en Science de la Sante; Boulkiemdé;
|
Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study |
Interventional |
Phase 3
|
Child, Only,Malaria,Falciparum
|
2020-06-05 |
2022-03-31 |
London School of Hygiene and Tropical Medicine |
No
|
| NCT01388452 |
MWI
|
Kamuzu Central Hospital; Lilongwe;
|
HIV Diagnosis in Hospitalized Malawian Infants |
Interventional |
Not Applicable
|
HIV Infections
|
2011-06-01 |
2012-12-01 |
University of North Carolina, Chapel Hill |
No
|
| NCT00054561 |
ZAF
|
Pretoria Academic Hospital; Pretoria;
|
Isotretinoin, Interferon Alfa, and Vitamin E in Treating Patients With Stage III or Stage IV Head and Neck Cancer |
Interventional |
Phase 3
|
Head and Neck Cancer
|
2003-08-01 |
2009-05-01 |
Eastern Cooperative Oncology Group |
No
|
| NCT02663700 |
|
|
Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso |
Interventional |
Phase 1
|
Plasmodium Falciparum Infection
|
2016-04-07 |
2018-12-17 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT03486691 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Preoperative Ultrasound as a Predictor for Difficulty in Bariatric Surgery |
Interventional |
Not Applicable
|
Obesity, Morbid
|
2018-02-01 |
2018-08-10 |
Minia University |
No
|
| NCT03108625 |
ZAF
|
Cape Trial Centre; Bellville;
|
Continuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of Age |
Interventional |
Phase 3
|
Depressive Disorder, Major
|
2017-03-01 |
2020-04-16 |
H. Lundbeck A/S |
No
|
| NCT00002551 |
ZAF
|
Pretoria Academic Hospital; Pretoria;
|
SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed |
Interventional |
Phase 3
|
Colorectal Cancer
|
1994-03-01 |
2008-10-01 |
Southwest Oncology Group |
No
|
| NCT02796326 |
|
|
Modified Endotracheal Balloon Dilator to Improve Patient Oxygenation and Allow Ventilation During Airway Procedures |
Interventional |
Not Applicable
|
Tracheal Stenosis
|
2016-10-01 |
2017-09-30 |
University of Cape Town |
No
|
| NCT03772509 |
TZA
|
Ifakara Health Institute; Dar es Salaam;
|
Use of Introduction Mode to Improve Interactive Voice Response Surveys in Bangladesh and Tanzania |
Interventional |
Not Applicable
|
Noncommunicable Diseases,Surveys and Questionnaires
|
2017-06-14 |
2017-08-18 |
Johns Hopkins Bloomberg School of Public Health |
No
|
| NCT02222493 |
ZAF
|
Jakaranda Hospital; Pretoria;
Manor Medical Center; Sandton;
Vincent Pallotti Hospital; Pinelands;
|
A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02). |
Interventional |
Phase 3
|
Rheumatoid Arthritis
|
2014-08-26 |
2017-06-01 |
Pfizer |
No
|
| PACTR202007754558749 |
MLI
|
Bandiagara Malaria Project; Bamoko; (BMP)
|
Randomized double-blinded controlled clinical trial to assess the efficacy of Dihydroartemisinin-Piperaquine compared to Sulfadoxine-Pyrimethamine associated to Amodiaquine in Seasonal Malaria Chemoprevention in school aged children from 6-15 years in Mali |
RCT |
|
Infections and Infestations
|
20-01-09 |
70-01-01 |
Universite des Sciences des Techniques et des Technologies de Bamako USTTB |
No
|
| NCT04213053 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Lees Screen in Concomitant Strabismus |
Interventional |
Not Applicable
|
Strabismus
|
2019-10-01 |
2021-02-01 |
Minia University |
No
|
| NCT01334190 |
ZAF
|
FHI 360; Pretoria;
|
A Prospective Observational Study of the Performance of Zarin in Kenya |
Observational |
|
Contraceptive Usage
|
2011-06-01 |
2013-02-01 |
FHI 360 |
No
|
| NCT02762539 |
|
|
Omega3 PUFA in Head Trauam |
Interventional |
Not Applicable
|
Traumatic Brain Injury
|
2016-06-01 |
2018-01-01 |
Mansoura University |
No
|
| NCT04416997 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Rheumatoid Arthritis Hematological Indices |
Observational |
|
Serum Albumin Low,Rheumatoid Arthritis
|
2020-03-01 |
2023-01-30 |
Assiut University |
No
|
| NCT00004859 |
ZAF
|
Netcare Unitas Hospital; Centurion;
Pretoria Academic Hospital; Pretoria;
|
Carboplatin, Paclitaxel, and Radiation Therapy With or Without Thalidomide in Patients With Stage III Non-small Cell Lung Cancer |
Interventional |
Phase 3
|
Lung Cancer
|
2000-01-01 |
2010-03-01 |
National Cancer Institute (NCI) |
No
|
| NCT02151890 |
Egypt
|
Al-Azhar University; Cairo;
|
Pregnancy After Stem Cell Transplantation in Premature Ovarian Failure |
Interventional |
Phase 1,Phase 2
|
Premature Ovarian Failure
|
2012-03-01 |
2014-05-01 |
Al-Azhar University |
No
|
| NCT00335374 |
ZAF, BFA, SLE
|
Beuke Oord 28; Pretoria;
Investigational Site Number 2040001; Cotonou;
Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS)
34 Military Hospital; Wilberforce;
E13 Renal Unit; Cape Town;
Groote Schuur Clinical Research Site; Cape Town;
Flexivest 14 Research Centre; Bellville;
Ward 21 CRS; Gauteng ;
FHI 360; Pretoria;
|
An Open Label SLV308 Safety Extension to Study S308.3.003 in Early PD Patients |
Interventional |
Phase 3
|
Early Stage Parkinson's Disease
|
2007-08-01 |
2008-11-01 |
Solvay Pharmaceuticals |
No
|
| NCT04778813 |
|
|
Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) |
Interventional |
Phase 4
|
Malaria,Burkina Faso
|
2021-06-01 |
2022-06-01 |
Centre national de recherche et de formation sur le paludisme |
No
|
| NCT03557281 |
|
|
An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis |
Interventional |
Phase 2
|
Tuberculosis
|
2019-03-27 |
2021-05-14 |
GlaxoSmithKline |
No
|
| NCT03512249 |
South Africa
|
Aurum Institute; Tembisa;
|
Study to Evaluate H56:IC31 in Preventing Rate of TB Recurrence |
Interventional |
Phase 2
|
Tuberculosis, Pulmonary
|
2019-01-31 |
2024-12-31 |
Aeras |
No
|
| NCT00089986 |
|
|
GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults |
Interventional |
Phase 2
|
Sepsis
|
2004-09-01 |
2007-04-15 |
GlaxoSmithKline |
No
|
| NCT01459328 |
|
|
Resource-Sparing Curative Treatment for Rectal Cancer |
Interventional |
Phase 3
|
Rectal Carcinoma
|
2009-09-01 |
|
International Atomic Energy Agency |
No
|
| NCT03133975 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Vitamin D Supplementation for Treatment of Dyslipidemia |
Interventional |
Phase 3
|
Dyslipidemias
|
2017-04-01 |
2019-07-01 |
Mansoura University |
No
|
| NCT02261662 |
|
|
Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV Infection |
Interventional |
Not Applicable
|
Vasculitis,Hepatitis C,Lichen Planus,Autoimmune Diseases
|
2014-06-01 |
2014-11-01 |
Tanta University |
No
|
| NCT02409680 |
COD, KEN
|
Kinshasa School of Public Health - Universite de Kinshasa; Kinshasa; (KSPH)
School of Medicine - Moi University; Eldoret;
|
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN) |
Interventional |
Not Applicable
|
Premature Birth
|
2016-03-23 |
2019-04-11 |
NICHD Global Network for Women's and Children's Health |
No
|
| NCT04777006 |
KEN
|
Partners in Health and Research Development; Thika; (PHRD)
|
Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform |
Interventional |
Phase 4
|
Depressive Disorder
|
2021-07-01 |
2024-10-31 |
RAND |
No
|
| NCT00119093 |
UGA
|
Tororo District Hospital; Tororo;
|
Home-based AIDS Care Project |
Interventional |
Not Applicable
|
HIV Infections
|
2003-05-01 |
2009-03-01 |
Centers for Disease Control and Prevention |
No
|
| NCT03440385 |
ZAF
|
Manor Medical Center; Sandton;
Mamma Clinic; Cape Town;
|
Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease |
Interventional |
Phase 3
|
Crohn Disease
|
2018-03-07 |
2023-07-10 |
Celgene |
No
|
| NCT01445938 |
BFA
|
Investigational Site Number 2040001; Cotonou;
|
Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria |
Interventional |
Phase 2
|
Malaria
|
2011-10-01 |
2012-01-01 |
Sanofi |
No
|
| NCT04274335 |
KEN, South Africa
|
Kar Geno Center Kisumu Women Center For Hope; Kisumu;
Madibeng Centre For Research; Brits; (MCR)
|
Pharmacokinetics and Pharmacodynamics of Tranexamic Acid in Women Having Caesarean Section Birth [WOMAN-PharmacoTXA] |
Interventional |
Phase 2
|
Pregnancy, High Risk
|
2020-12-18 |
2021-10-01 |
London School of Hygiene and Tropical Medicine |
No
|
| NCT00731419 |
|
|
Randomised Trial Comparing Metal and Plastic Biliary Stents Stents for Palliating Malignant Jaundice |
Interventional |
Phase 4
|
Biliary Obstruction
|
2007-06-01 |
2009-08-01 |
University of Cape Town |
No
|
| NCT00998764 |
ZAF
|
Netcare St. Augustine Hospital; Durban;
|
A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients |
Interventional |
Phase 3
|
Alzheimer Disease
|
2009-12-01 |
2012-11-01 |
Pfizer |
No
|
| NCT03782207 |
ZAF
|
Tara Hospital; Cape Town;
|
A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice |
Observational |
|
Urothelial Carcinoma,Small Cell Lung Cancer,Non-Small Cell Lung Cancer
|
2019-02-07 |
2024-12-19 |
Hoffmann-La Roche |
No
|
| NCT04199286 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Horizontal Strabismus Surgery |
Interventional |
Not Applicable
|
Strabismus
|
2019-03-01 |
2020-10-01 |
Minia University |
No
|
| NCT01357668 |
ZAF
|
Clinical Research Unit; Gauteng;
Panaroma Medical Centre; Parow;
|
An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis |
Observational |
|
Juvenile Idiopathic Arthritis
|
2013-01-31 |
2029-12-31 |
Bristol-Myers Squibb |
No
|
| NCT04069819 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
The Phosphodiesterase 3 Inhibitor Cilostazol as an Adjunct to Antidepressants in Major Depressive Disorder Patients |
Interventional |
Not Applicable
|
Major Depressive Disorder
|
2017-01-01 |
2021-01-31 |
Sadat City University |
No
|
| NCT03284645 |
|
|
Viral and Antiretroviral Dynamics in HIV-1 Mother-to-Child Transmission Fluids |
Observational |
|
Human Immunodeficiency Virus Infection
|
2017-12-22 |
2020-12-22 |
Obafemi Awolowo University |
No
|
| NCT00122486 |
CMR
|
Care and Health Program; Yaounde;
|
Study of Tenofovir Disoproxil Fumarate (TDF) for Prevention of HIV |
Interventional |
Phase 2
|
HIV Infections
|
2004-07-01 |
2006-03-01 |
FHI 360 |
No
|
| NCT01061151 |
|
|
Evaluating Strategies to Reduce Mother-to-Child Transmission of HIV Infection in Resource-Limited Countries |
Interventional |
Phase 3
|
HIV Infections
|
2011-03-01 |
2016-09-01 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT03166943 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
the Possible Effect of the Antiviral Inhibitors for Treatment of Hepatitis C Virus Infection in Cardiac Function |
Interventional |
Not Applicable
|
Hepatitis
|
2017-05-10 |
2020-12-01 |
Assiut University |
No
|
| NCT03395184 |
TUN, ZAF
|
La Rabta hospital Tunis; Tunis;
Lenasia Clinical Trial Centre; Johannesburg;
|
Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF‑06700841 In Subjects With Moderate To Severe Crohn's Disease |
Interventional |
Phase 2
|
Crohn's Disease
|
2018-02-02 |
2022-11-30 |
Pfizer |
No
|
| NCT03970408 |
EGY
|
Ain Shams University; Cairo;
|
Median Nerve Excursion During Neurodynamic Mobilization |
Observational |
|
CTS
|
2019-05-01 |
2020-10-01 |
Aliaa Rehan Youssef |
No
|
| NCT04657640 |
|
|
School-Based Assessment of Micronutrient Interventions in Adolescents in Burkina Faso |
Interventional |
Phase 3
|
Anemia
|
2020-12-11 |
2021-11-30 |
Harvard School of Public Health |
No
|
| NCT02678117 |
|
|
Analgesic Potentials of Preoperative Pregabalin,Magnesium Sulphate and Their Combination in Acute Post-thoracotomy Pain |
Interventional |
Phase 3
|
Postoperative Pain
|
2015-07-01 |
2019-02-01 |
National Cancer Institute, Egypt |
No
|
| NCT00654979 |
ZAF
|
Universitas Hospital; Bloemfontein;
|
A Pivotal Study to Evaluate the Safety and Effectiveness of RMT Medical Technology's SafeFlo® Vena Cava Filter |
Interventional |
Not Applicable
|
Pulmonary Embolism
|
2003-07-01 |
2008-03-01 |
RMT Medical Technologies, Ltd. |
No
|
| NCT01460095 |
TZA
|
Bagamoyo District Hospital; Bagamoyo;
|
Improving Access to HbA1c in Sub Saharan Africa |
Interventional |
Not Applicable
|
Diabetes Mellitus
|
2009-03-01 |
2011-12-01 |
Yaounde Central Hospital |
No
|
| NCT00113854 |
ZAF
|
Department of Paediatrics and Child Health; Panorama;
|
Mannitol as Adjunct Therapy for Childhood Cerebral Malaria |
Interventional |
Phase 3
|
Cerebral Malaria
|
2004-10-01 |
2005-05-01 |
Makerere University |
No
|
| NCT00197067 |
|
|
A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Candidate Vaccines RTS,S/AS02D (0.5 mL Dose) and RTS,S/AS02A (0.25 mL Dose) Administered IM According to a 0, 1, 2 Month Vaccination Schedule in Children Aged 3 to 5 Years Living in a Malaria-endemic Region of Mozambique. |
Interventional |
Phase 1
|
Malaria
|
2004-03-15 |
2005-04-26 |
GlaxoSmithKline |
No
|
| NCT00145223 |
EGY
|
Ain Shams University; Cairo;
|
Research for Elim of Filariasis |
Observational |
|
W. Bancrofti Filariasis
|
2003-08-01 |
2005-07-01 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT00500331 |
|
|
Dose-Ranging Study in Treatment Naive Type 2 Diabetes Mellitus(T2DM) |
Interventional |
Phase 2
|
Diabetes Mellitus, Type 2
|
2007-01-23 |
2008-02-14 |
GlaxoSmithKline |
No
|
| NCT01578850 |
ZAF
|
Vincent Pallotti Hospital; Pinelands;
Winelands Medical Research Centre; Cape Winelands;
|
Study Conducted in Subjects With Rheumatoid Arthritis Who Have Moderate to Severe Disease Activity Despite Methotrexate Therapy With or Without Other Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)for at Least 12 Weeks Prior to Screening |
Interventional |
Phase 4
|
Rheumatoid Arthritis
|
2012-07-01 |
2015-03-01 |
Pfizer |
No
|
| NCT04389788 |
EGY
|
Faculty of Medicine - Zagazig University; Zagazig;
|
Treatment of Patients With Periorbital Hyperpigmentation |
Interventional |
Not Applicable
|
Periorbital Hypermelanosis
|
2020-02-12 |
2020-07-01 |
Sohag University |
No
|
| NCT03024957 |
EGY
|
Assiut University; Assiut;
|
Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on Immunity |
Interventional |
Phase 1,Phase 2
|
Immune System Suppression
|
2017-01-01 |
2020-03-01 |
Assiut University |
No
|
| NCT04844905 |
NGA
|
College of Medicine - University of Lagos; Lagos;
|
Adjunctive Ivermectin Mass Drug Administration for Malaria Control |
Interventional |
Phase 3
|
Scabies,Hook Worm,Strongyloidiasis,Malaria,Falciparum,Lymphatic Filariasis,Soil Transmitted Helminths,Neglected Tropical Diseases
|
2021-05-01 |
2023-08-01 |
London School of Hygiene and Tropical Medicine |
No
|
| NCT04824131 |
ZWE, UGA, ZAF
|
Spilhaus Clinical Research Site - Zimbabwe National Family Planning Council Clinic; Harare; (ZNFPC CRS)
MU-JHU Research Collaboration; Kampala; (MUJHU CARE LTD CRS)
Ward 21 CRS; Gauteng ;
|
Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Females - A Sub-study of HPTN 084 |
Interventional |
Phase 2
|
HIV Infections
|
2020-11-04 |
2024-05-01 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT04182399 |
EGY
|
Ain Shams University; Cairo;
|
Role of Zonisamide in Advanced Parkinson's Disease (PD) in Egyptian Population: Pilot Study |
Interventional |
Not Applicable
|
Parkinson Disease
|
2020-04-01 |
2023-01-01 |
Ain Shams University |
No
|
| NCT04077411 |
|
|
Approaches and Decisions for Acute Pediatric TBI Trial |
Observational |
|
Severe Traumatic Brain Injury
|
2014-02-20 |
2018-08-28 |
University of Pittsburgh |
No
|
| NCT00223990 |
KEN
|
Walter Reed Project Clinical Research Center - Kenya Medical Research Institute; Nairobi; (WRP-KEMRI CRS)
|
Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine |
Interventional |
Phase 2
|
Malaria, Falciparum
|
2005-04-08 |
2007-06-01 |
U.S. Army Medical Research and Development Command |
No
|
| NCT02435992 |
ZAF
|
Louis Pasteur Hospital; Pretoria;
Endocare Research; Cape Town;
Manor Medical Center; Sandton;
Tiervlei Trial Centre; Bellville; (TTC)
Mamma Clinic; Cape Town;
|
Safety and Efficacy Trial of RPC1063 for Moderate to Severe Ulcerative Colitis |
Interventional |
Phase 3
|
Ulcerative Colitis
|
2015-06-17 |
2020-06-17 |
Celgene |
No
|
| NCT00003175 |
|
|
Fluorouracil in Treating Patients With Recurrent or Metastatic Bladder Cancer |
Interventional |
Phase 2
|
Bladder Cancer,Urethral Cancer,Transitional Cell Cancer of the Renal Pelvis and Ureter
|
1997-12-01 |
2009-03-01 |
Medical Research Council |
No
|
| NCT04094493 |
EGY
|
Assiut University; Assiut;
|
Vit D Role in Post Thyroidectomy Hypocalcemia |
Interventional |
Early Phase 1
|
Thyroid Diseases
|
2019-10-01 |
2020-09-30 |
Assiut University |
No
|
| NCT02469298 |
|
|
Safety, Tolerability and Clinical Effect of Danirixin in Adults With Influenza |
Interventional |
Phase 2
|
Virus Diseases
|
2015-06-01 |
2016-04-25 |
GlaxoSmithKline |
No
|
| NCT02684019 |
EGY
|
Theodor Bilharz Research Institute; Giza; (TBRI)
|
Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure |
Interventional |
Phase 3
|
Lack of Drug Action
|
2016-01-01 |
2016-11-01 |
Theodor Bilharz Research Institute |
No
|
| NCT03614533 |
BFA
|
Groupe de Recherche Action en Santé; Ouagadougou; (GRAS)
|
Typhoid Conjugate Vaccine Trial Among Children Younger Than 2 Years in Ouagadougou, Burkina Faso |
Interventional |
Phase 2
|
Typhoid
|
2018-12-03 |
2019-08-22 |
University of Maryland, Baltimore |
No
|
| NCT00866619 |
|
|
Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa |
Interventional |
Phase 3
|
Malaria
|
2009-03-27 |
2014-01-31 |
GlaxoSmithKline |
No
|
| NCT02568137 |
GHA
|
Kumasi Centre for Collaborative Research in Tropical Medicine - Kwame Nkrumah University of Science and Technology; Kumasi; (KCCR)
|
Phone-based Intervention Under Nurse Guidance After Stroke |
Interventional |
Not Applicable
|
Stroke,Hypertension
|
2017-01-01 |
2017-07-01 |
Medical University of South Carolina |
No
|
| NCT04357028 |
|
|
Measles Vaccine in HCW |
Interventional |
Phase 3
|
Covid19
|
2020-07-13 |
2020-11-01 |
Kasr El Aini Hospital |
Yes
|
| NCT04099875 |
EGY
|
National Liver Institute; Menofia;
|
Ultrasonography for Nutritional Assesment in Cirrhotic Patients |
Observational |
|
Nutrition Assessment
|
2019-04-01 |
2021-04-01 |
National Liver Institute, Egypt |
No
|
| NCT01276509 |
ZAF
|
Mamma Clinic; Cape Town;
|
Study To Test Whether PF-00547659 Is Safe And Improves Disease Symptoms In Patients With Crohn's Disease |
Interventional |
Phase 2
|
Crohn's Disease
|
2011-04-06 |
2015-10-09 |
Shire |
No
|
| NCT02251704 |
|
|
Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa |
Interventional |
Not Applicable
|
Malaria
|
2014-10-22 |
2024-06-15 |
GlaxoSmithKline |
No
|
| NCT03825952 |
UGA
|
Kabwohe Clinical Research Centre; Sheema;
|
Optimizing mHealth for Adherence Monitoring and Intervention |
Interventional |
Not Applicable
|
HIV/AIDS
|
2018-03-28 |
2021-12-01 |
Massachusetts General Hospital |
No
|
| NCT04312581 |
|
|
Extracorporeal Shock Wave Therapy on Wrist and Hand Functions in Spastic Chronic Stroke Patients |
Interventional |
Not Applicable
|
Stroke,Spasticity
|
2020-03-21 |
2020-07-29 |
Tanta University |
No
|
| NCT01108289 |
Ghana
|
Kintampo Health Research Centre; Kintampo; (KHRC)
|
Effect of Prophylactic Administration of Oxytocin in Uniject™ on Postpartum Hemorrhage at Home Births in Ghana |
Interventional |
Not Applicable
|
Postpartum Hemorrhage
|
2011-04-01 |
2012-12-01 |
Johns Hopkins Bloomberg School of Public Health |
No
|
| NCT01670032 |
ZAF
|
Synopsis Research; Cape Town;
Langeberg Clinical Trials; Cape Town;
Setshaba Research Centre; Soshanguve; (SRC)
|
Vehicle Controlled Efficacy and Safety Study of Two Dose Regimens of CD07223 1.5% Topical Gel in Impetigo |
Interventional |
Phase 2,Phase 3
|
Impetigo
|
2012-08-01 |
2013-08-01 |
NovaBay Pharmaceuticals, Inc. |
No
|
| NCT03933280 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Conscious Sedation for Cataract Operations Under Topical Anaesthesia |
Interventional |
Phase 2
|
Conscious Sedation
|
2019-07-01 |
2021-01-01 |
Menoufia University |
No
|
| NCT02448615 |
ZMB
|
Choma District Health Office; Choma;
|
Birth Cohort in Coast Province, Kenya |
Observational |
|
Morbidity,Mortality,Child Behaviour,Child Development
|
2015-07-01 |
2016-04-01 |
The Hospital for Sick Children |
No
|
| NCT03498092 |
EGY
|
Oncology Centre - Mansoura University Hospitals; Mansoura;
|
Dexmedetomidine in Serratus Plane Block for Mastectomy |
Interventional |
Not Applicable
|
Postoperative Pain
|
2016-08-08 |
2018-10-08 |
Alaa Mazy |
No
|
| NCT04206241 |
ZWE
|
Beitbridge District Hospital; Beitbridge;
|
Assessing the Feasibility, Acceptability and Effects Of HIV Birth Testing In Maternity Settings In Zimbabwe |
Observational |
|
HIV/AIDS,HIV Infections,Infant Morbidity,Perinatal HIV Infection
|
2018-01-01 |
2022-12-31 |
Elizabeth Glaser Pediatric AIDS Foundation |
No
|
| NCT02674126 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
The Efficacy of Maternal Sound for Pediatric Patients Undergoing Cardiac Surgery |
Interventional |
Phase 2
|
Maternal-Fetal Relations
|
2016-01-01 |
2016-09-01 |
Assiut University |
No
|
| NCT03393520 |
ZAF
|
Cape Trial Centre; Bellville;
Apollo Clinical Research; Johannesburg;
Medical and Dental Centre; Randburg;
|
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type |
Interventional |
Phase 3
|
Agitation in Patients With Dementia of the Alzheimer's Type
|
2017-10-13 |
2022-07-01 |
Avanir Pharmaceuticals |
No
|
| NCT00611455 |
|
|
Investigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to MTX Therapy |
Interventional |
Phase 3
|
Arthritis, Rheumatoid
|
2008-01-01 |
2013-07-15 |
GlaxoSmithKline |
No
|
| NCT04826120 |
TUN
|
Service de Rhumatologie - Hopital Mongi Slim; Tunis ;
|
Continuous Versus Intermittent Administration of Epidural Analgesia During Labor |
Interventional |
Not Applicable
|
Epidural; Analgesia
|
2020-06-01 |
2021-01-31 |
Mongi Slim Hospital |
No
|
| NCT04341662 |
South Africa
|
University of Witwatersrand; Johannesburg;
|
A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth |
Interventional |
Not Applicable
|
Post-Partum Haemorrhage
|
2020-10-13 |
2023-01-31 |
University of Birmingham |
No
|
| NCT03126838 |
EGY
|
National Heart Institute; Giza;
|
Diaphragmatic Dysfunction and Cardiac Surgery; Perioperative Assessment and Effect on Outcome |
Observational |
|
Diaphragm Disease
|
2017-03-01 |
2018-09-01 |
National Heart Institute, Egypt |
No
|
| NCT04590586 |
ZAF, BEN
|
Groote Schuur Clinical Research Site; Cape Town;
Hopital de Zone de Natitingou; Natitingou;
|
Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients |
Interventional |
Phase 3
|
COVID-19
|
2020-11-24 |
2022-08-25 |
Amgen |
Yes
|
| NCT04285450 |
|
|
The Clinical Effect of Vitamin K Administration in Type 2 Diabetic Patients |
Interventional |
Phase 4
|
Diabetes Mellitus, Type 2
|
2020-06-01 |
2021-03-01 |
Cairo University |
No
|
| NCT03467958 |
ZAF
|
Louis Pasteur Hospital; Pretoria;
Manor Medical Center; Sandton;
Mamma Clinic; Cape Town;
|
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease |
Interventional |
Phase 3
|
Crohn Disease
|
2018-08-22 |
2026-09-24 |
Celgene |
No
|
| NCT04631016 |
ZAF
|
Groote Schuur Clinical Research Site; Cape Town;
|
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis |
Interventional |
Phase 2
|
Chronic Bronchitis,Chronic Obstructive Pulmonary Disease (COPD)
|
2020-12-14 |
2022-12-30 |
AstraZeneca |
Yes
|
| NCT00436007 |
|
|
Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen |
Interventional |
Phase 2
|
Malaria
|
2007-04-30 |
2009-10-07 |
GlaxoSmithKline |
No
|
| NCT01860495 |
Egypt
|
Al-Azhar University; Cairo;
|
Gingival Crevicular Fluid Bone Morphogenetic Protein - 2 Release Profile Following the Use of Perforated Membrane |
Observational |
|
Periodontal Pocket
|
2012-03-01 |
2012-12-01 |
Al-Azhar University |
No
|
| NCT01512823 |
|
|
Randomised Trial of Two Educational Intervention for Improving Evidence-based Practice Knowledge, Atttitudes and Practice |
Interventional |
Not Applicable
|
Health Knowledge, Attitudes, Practice
|
2007-11-01 |
2011-03-01 |
University of Cape Town |
No
|
| NCT03747094 |
|
|
Sedation of Morbidly Obese for Balloon Insertion |
Interventional |
Not Applicable
|
Morbid Obesity
|
2018-12-01 |
2019-04-15 |
Mansoura University |
No
|
| NCT03898726 |
EGY
|
Ain Shams University; Cairo;
|
Laparoscopic Versus Transvaginal Cuff Closure |
Interventional |
Not Applicable
|
Vaginal Hematoma,Vaginal Infection,Vaginal Cuff Dehiscence
|
2018-03-27 |
2019-04-01 |
El-Galaa Military Medical Complex |
No
|
| NCT03565588 |
|
|
Manicaland VMMC Uptake Through Behavioural Incentives Trial |
Interventional |
Not Applicable
|
HIV/AIDS
|
2018-07-07 |
2021-01-01 |
Simon Gregson |
No
|
| NCT03254901 |
EGY
|
Assiut University; Assiut;
|
Detection of Hepatitis C Infection by Oraquick Test Among Health Care Workers |
Observational |
|
Hepatitis C
|
2018-01-01 |
2018-07-01 |
Assiut University |
No
|
| NCT00387764 |
|
|
Extension Study to VEG105192 to Assess Pazopanib in Patients With Advanced/Metastatic Renal Cell Cancer |
Interventional |
Phase 3
|
Carcinoma, Renal Cell
|
2006-09-01 |
2012-10-01 |
GlaxoSmithKline |
No
|
| NCT04666311 |
ZAF
|
Mamma Clinic; Cape Town;
National District Hospital; Bloemfontein;
|
Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis |
Observational |
|
HIV,Covid-19,Pulmonary Tuberculosis,Tuberculosis Diagnosis
|
2021-03-01 |
2022-05-01 |
Klaus Reither |
Yes
|
| NCT04673487 |
KEN
|
Clinical Research Annexe - Kenya Medical Research Institute; Siaya; (KEMRI)
|
Commercial Typhoid Tests Validation |
Observational |
|
Typhoid Fever
|
2021-01-01 |
2021-12-01 |
Kenya Medical Research Institute |
No
|
| NCT00823979 |
South Africa
|
University of Witwatersrand; Johannesburg;
Desmond Tutu HIV Foundation; Cape Town;
|
A Phase 2B Multicenter, Randomized, Comparative Trial Of UK-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleos(t)Ide Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced HIV-1 Infected Subjects With Evidence Of NNRTI Resistant HIV-1 |
Interventional |
Phase 2
|
HIV-1
|
2009-03-25 |
2012-10-18 |
Pfizer |
No
|
| NCT00169078 |
|
|
Impact of Insecticide-treated Curtains on Antimalarial Drug Resistance |
Interventional |
Not Applicable
|
Malaria
|
2002-07-01 |
2002-12-01 |
London School of Hygiene and Tropical Medicine |
No
|
| NCT03087084 |
|
|
RESpiration deTection From Implanted Cardiac Devices in Subjects With Heart Failure (REST-HF) |
Interventional |
Not Applicable
|
Heart Failure
|
2018-08-07 |
2020-04-01 |
Medtronic BRC |
No
|
| NCT01990625 |
COD, KEN
|
Kinshasa School of Public Health - Universite de Kinshasa; Kinshasa; (KSPH)
School of Medicine - Moi University; Eldoret;
|
A Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings |
Interventional |
Not Applicable
|
Eclampsia,Pregnancy,Stillbirth,Placenta Previa,Fetal Growth Restriction
|
2014-04-01 |
2016-09-01 |
NICHD Global Network for Women's and Children's Health |
No
|
| NCT02168322 |
EGY
|
Ain Shams University; Cairo;
|
Perforated Barrier Membranes Maintain Physiologic Gingival Crevicular Fluid Growth Factor Levels |
Interventional |
Not Applicable
|
Membrane Alteration,Vascular Endothelial Growth Factor Overexpression
|
2013-10-01 |
2014-03-01 |
Al-Azhar University |
No
|
| NCT04625452 |
ZAF
|
National District Hospital; Bloemfontein;
|
Feasibility and Efficacy of Brief Behavior Change Counseling on Lifestyle in Hypertensive and Diabetics Participants |
Interventional |
Not Applicable
|
Diabetes,Life Style,Hypertension
|
2020-08-13 |
2021-03-30 |
University of Malawi College of Medicine |
No
|
| NCT00138307 |
GHA
|
Navrongo Health Research Centre; Navrongo;
|
Correlates of Protection in Ghana |
Observational |
|
Malaria
|
|
2006-03-01 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT01535469 |
|
|
Operational Research for Cryptococcal Antigen Screening |
Interventional |
Phase 4
|
Cryptococcosis,Cryptococcal Meningitis,Cryptococcus Neoformans
|
2012-07-01 |
2015-06-01 |
University of Minnesota |
No
|
| NCT00457691 |
BFA
|
Investigational Site Number 2040001; Cotonou;
|
Study Of FOLFIRI Chemotherapy With Or Without Sunitinib In Patients With Metastatic Colorectal Cancer |
Interventional |
Phase 3
|
Metastatic Colorectal Cancer
|
2007-06-01 |
2010-03-01 |
Pfizer |
No
|
| NCT02391415 |
ZAF
|
Desmond Tutu TB Centre - Stellenbosch University; Cape Town;(DTTC)
|
Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa |
Interventional |
Phase 2
|
Tuberculosis
|
2015-06-01 |
2017-11-01 |
Serum Institute of India Pvt. Ltd. |
No
|
| NCT03591575 |
EGY
|
Ain Shams University; Cairo;
|
Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children |
Interventional |
Phase 4
|
Iron Overload,Beta Thalassemia Major Anemia
|
2018-11-09 |
2020-11-01 |
Chiesi Canada Corp |
No
|
| NCT04829630 |
SEN, MDG
|
Institut Pasteur; Dakar;
Institute Pasteur de Madagascar; Antananarivo;
|
Immunity Persistence After Abridged Intradermal Rabies PEP |
Interventional |
Not Applicable
|
Rabies
|
2021-05-01 |
2023-05-01 |
Institut Pasteur |
No
|
| NCT03088410 |
|
|
Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gaborone, Botswana |
Interventional |
Phase 4
|
HIV,Diabetes Mellitus,Insulin Sensitivity
|
2016-08-22 |
2022-03-31 |
Ann & Robert H Lurie Children's Hospital of Chicago |
No
|
| NCT04301531 |
GHA
|
Virology Department - Noguchi Memorial Institute For Medical Research University Of Ghana; Legon; (NMIMR)
|
Determining the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence in Ghana |
Interventional |
Not Applicable
|
Malaria Asymptomatic Parasitaemia
|
2020-03-01 |
2022-01-31 |
Noguchi Memorial Institute for Medical Research |
No
|
| NCT03496493 |
|
|
COMparison of Portable Fingertip Versus Conventional Pulse OximeteRs Trial |
Observational |
|
Hypoxemia,Anesthesia
|
2018-04-15 |
2018-12-31 |
University of Cape Town |
No
|
| NCT01912521 |
KEN
|
Ekialo Kiona Center; Homa Bay;
|
Mfangano Island Healthy Networks Impact Study |
Interventional |
Not Applicable
|
HIV
|
2011-11-01 |
2013-12-01 |
University of California, San Francisco |
No
|
| NCT04447469 |
ZAF, AGO, South Africa, SEN, MOZ, NGA, ZWE, KEN, CMR, DZA
|
Mediclinic Sandton; Bryanston;
Little Company of Mary Hospital; Pretoria;
Iatros International; Bloemfontein;
Instituto de Combate e Controlo das Tripanossomiases; Luanda; (ICCT)
Manor Medical Center; Sandton;
Cardiology Clinical Research; Alberton;
Africa Health Research Institute; Durban;
Task Eden Clinical Research Centre; George;
Niakhar Demographic Surveillance System; Dakar;(DS IDR)
Medigate Medical Centre; Umhlanga;
Polana Caniço Health Research and Training Center - Instituto Nacional de Saúde and Ministry of Health; Cidade de Maputo; (CISPOC)
Faculty of Health Sciences - University of Cape Town; Cape Town; (UCT)
Tiervlei Trial Centre; Bellville; (TTC)
Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH)
St Mary's Clinical Research Site -The University of Zimbabwe College of Health Sciences Clinical Trials Research Centre; Harare; (UZCHS-CTRC)
Bondo Clinic - Bondo District Hospital; Bondo;
Care and Health Program; Yaounde;
Centre Hospitalo-Universitaire de Constantine; Constantine; (CHU)
Instituto Nacional de Saúde; Maputo; (INS)
Emery Clinical Services; Alberton;
Bertoni Mercy Clinic; Pretoria;
Limpopo Clinical Research Initiative; Limpompo;
University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF)
Marondera Provincial Hospital; Harare;
|
Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation |
Interventional |
Phase 2,Phase 3
|
COVID
|
2020-07-27 |
2022-02-01 |
Kiniksa Pharmaceuticals, Ltd. |
Yes
|
| NCT02092766 |
COD
|
Kinshasa School of Public Health - Universite de Kinshasa; Kinshasa; (KSPH)
|
Parenteral Artesunate Compared to Quinine as a Cause of Late Anaemia in African Children With Malaria |
Interventional |
Phase 4
|
Anaemia
|
2014-06-01 |
2015-04-01 |
University of Oxford |
No
|
| NCT03152812 |
EGY
|
Assiut University; Assiut;
|
Functional Outcome of Free Muscle Flaps Versus Free Skin Flaps for Post-traumatic Foot Plantar Surface Reconstruction |
Observational |
|
Best Tissue Constituent for Plantar Surface
|
2017-03-01 |
2019-03-01 |
alhussein Ahmed Mahmoud El-Dahshan |
No
|
| NCT03543592 |
EGY
|
Kasr El-Aini Hospital - Kasr El Aini Faculty of Medicine Cairo University; El Azab;
|
Three-dimensional Power Doppler in the Diagnosis of Endometrial Lesions in Patients With Postmenopausal Bleeding |
Interventional |
Not Applicable
|
Postmenopausal Bleeding
|
2018-06-01 |
2020-08-15 |
Cairo University |
No
|
| NCT04576455 |
BWA, KEN, TUN, GHA, BFA, Nigeria, NGA, ZAF, CMR, ZWE, EGY, DZA, MOZ, Malawi
|
Francistown Academic Hospital; Francistown;
International Cancer Institute; Uasin Gishu;
Institut De Nutrition; Tunis;
Dodowa Health Research Centre; Dodowa; (DHRC)
Centre de Recherche en Santé de Nouna - Ministère de la Santé; Nouna; (CRSN)
First Technical University; Ibadan;
Zankli Research Centre; Abuja;
Iatros International; Bloemfontein;
Allergology Diagnostic Clinical Research Centre; Western Cape; (ADCRU)
Hopelands Cancer Centre; Durban;
City Park Medical Centre; Cape Town;
Manor Medical Center; Sandton;
Rosebank Clinic; Randburg;
Mary Potter Oncology Centre; Pretoria;
Cancercare - Langenhoven Drive Oncology Centre; Port Elizabeth;
Hopital General De Yaoundé; Yaoundé;
Deborah Retief Memorial Hospital; Mochudi;
Chidamoyo Christian Hospital; Karoi;
Rustenburg CRS; Rustenburg;
New Specialist Outpatient Department; Cape Town;
Center for Clinical Care and Clinical Research; Abuja; (CCCRN)
Durban Medical Centre; Durban;
Netcare Christiaan Barnard Memorial Hospital; Cape Town;
Aurum Institute; Rustenburg;
Health Insurance Hospital; Cairo;
PAREXEL Port Elizabeth; Port Elizabeth;
Department of Medical Microbiology Parasitology - College of Medicine University of Ibadan; Oyo;
Curo Oncology; Pretoria;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
Sandton Oncology Cancer Centre; Sandton;
Centre Hospitalo-universitaire Bologhine Hospital; Algiers;
St Mary's Clinical Research Site -The University of Zimbabwe College of Health Sciences Clinical Trials Research Centre; Harare; (UZCHS-CTRC)
Cooper Centre; Durban;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Faculty of Medicine - Minia University; El Menia;
Eastleigh Breast Care Centre; Pretoria;
Investigator Clinic; Giza;
Nasser Institute for Research and Treatment; Cairo;
Centre Anti-Cancer; Annaba;
Centre Hospitalo-Universitaire d'Oran; Oran; (CHU)
Junju Dispensary; Kilifi;
Hiway Medical Center; Durban;
The Aga Khan University Hospital; Nairobi;
Instituto Nacional de Saúde; Maputo; (INS)
Clinical Research Center - Muelmed Hospital; Pretoria;
NESTRA KLINIkAL; Ibadan;
Cancer Centre - Tanta University; Tanta;
Netcare Moot General Hospital; Pretoria;
College of Medicine - University of Malawi; Blantyre;
Oncology department - University of Witwatersrand; Johannesburg;
Outeniqua GVI Oncology; George;
Department of Oncology - University of the Free State; Bloemfontein;
Marondera Provincial Hospital; Harare;
|
A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (acelERA Breast Cancer) |
Interventional |
Phase 2
|
Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
|
2020-11-27 |
2024-01-31 |
Hoffmann-La Roche |
No
|
| NCT03509168 |
|
|
The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy. |
Interventional |
Phase 2,Phase 3
|
Uterine Fibroid
|
2018-01-10 |
2018-06-03 |
Makerere University |
No
|
| NCT02817971 |
KEN
|
Kisumu County Hospital; Kisumu;
|
Effect of Enhanced Feedback to Hospitals in an Emerging Clinical Information Network |
Interventional |
Not Applicable
|
Pneumonia
|
2016-03-01 |
2016-12-01 |
KEMRI-Wellcome Trust Collaborative Research Program |
No
|
| NCT01498419 |
TZA
|
Ifakara Health Institute; Dar es Salaam;
|
Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002) |
Interventional |
Phase 2
|
Pulmonary Tuberculosis
|
2012-03-01 |
2013-07-01 |
Global Alliance for TB Drug Development |
No
|
| NCT04422106 |
|
|
Predictors of Intestinal Anastomosis Leakage, Application of New Predictors and New Scores |
Interventional |
Not Applicable
|
Anastomotic Leak
|
2020-06-17 |
2020-12-01 |
Mansoura University |
No
|
| NCT03735121 |
KEN, ZAF, GHA, Nigeria, DZA, EGY, ZWE, TUN, NAM, TZA, CMR, MOZ, NGA, BEN, Mozambique, UGA
|
International Cancer Institute; Uasin Gishu;
Department of Medicine - University of Cape Town; Cape Town;
Charlotte Maxeke Johannesburg Academic Hospital; Johannesburg;
Dodowa Health Research Centre; Dodowa; (DHRC)
First Technical University; Ibadan;
Garden City Clinic; Johannesburg;
Hopelands Cancer Centre; Durban;
Centre Anti Cancer de Blida; Rouïba;
Department of Radiotherapy - Addington Hospital; Durban;
Misr University for Science and Technology Hospital; Giza;
EgyBrit Medical Centre; Cairo;
Rosebank Clinic; Randburg;
Stikland Hospital; Cape Town;
The Medical Oncology Centre of Rosebank; Randburg;
Global Clinical Trials; Pretoria;
MediTrials (Pty) Ltd; Cape Town;
Dar El-Salam Oncology Center; Cairo;
Montana Hospital; West Coast;
Richards Bay Trial Center - Bay Hospital; KwaZulu Natal;
New Kasr El Eini Teaching Hospital; El Tagamoa El Khames;
Durban Oncology Centre; Durban;
Eugene Park medical Centre; Pretoria;
Durban Medical Centre; Durban;
Centre Pierre-et-Marie-Curie; Sidi M'Hamed; (CPMC)
Winelands Medical Research Centre; Cape Winelands;
Pretoria Heart Hospital; Pretoria;
Curo Oncology; Pretoria;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
Tara Hospital; Cape Town;
Sandton Oncology Cancer Centre; Sandton;
St. James's Hospital Life Health; East London;
Africa University Clinical Research Centre; Mutare; (AUCRC)
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Faculty of Medicine - Minia University; El Menia;
East Central Hospital; Windhoek;
Investigator Clinic; Giza;
Wilgers Oncology Centre - Wilgers Hospital; Pretoria;
VX Pharma; Pretoria;
Bugando medical Centre; Mwanza;
Centre Anti-Cancer; Annaba;
Centre Pasteur du Cameroun; Yaoundé; (CPC)
Junju Dispensary; Kilifi;
South Valley University; Qena;
Instituto Nacional de Saúde; Maputo; (INS)
Clinical Research Center - Muelmed Hospital; Pretoria;
RK Khan Hospital; Durban;
NESTRA KLINIkAL; Ibadan;
Rheumatology Department Faculty of Medicine - Ain Shams University; El Mohamady;
Cancer Centre - Tanta University; Tanta;
Ain Shams University; Cairo;
Africa International Research; Cape Town;
Centre de Diagnostic et de Traitement de la Tuberculose de Matéri; Matéri;
Moriana Clinical Research; Free State;
Netcare Moot General Hospital; Pretoria;
Centro de Investigação em Saúde de Manhiça; Manhica; (CISM)
Military Hospital; Accra;
Oncology department - University of Witwatersrand; Johannesburg;
Tororo District Hospital; Tororo;
Outeniqua GVI Oncology; George;
Marondera Provincial Hospital; Harare;
|
A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer |
Interventional |
Phase 3
|
Non-Small Cell Lung Cancer
|
2018-12-27 |
2024-03-31 |
Hoffmann-La Roche |
No
|
| NCT03009604 |
EGY
|
Assiut University; Assiut;
|
Does Simethicone Improve Operative Field in Gynecological Operations |
Interventional |
Phase 3
|
Benign Gynecologic Neoplasm
|
2017-01-01 |
2017-05-01 |
Assiut University |
No
|
| NCT03858998 |
TZA
|
Bugando medical Centre; Mwanza;
|
Reducing Post-Hospital Mortality in HIV-infected Adults in Tanzania |
Interventional |
Phase 3
|
HIV Infections
|
2019-03-05 |
2023-05-31 |
Weill Medical College of Cornell University |
No
|
| NCT04488250 |
BWA
|
University of Botswana; Gaborone;
|
Robot-Assisted Rehabilitation After HIV-Associated Stroke: Botswana |
Interventional |
Not Applicable
|
Stroke,HIV/AIDS
|
2019-10-01 |
2023-08-01 |
University of Pennsylvania |
No
|
| NCT04209920 |
EGY
|
Ain Shams University; Cairo;
|
A Comparison of Two Different Management Techniques for Extensive Molar Defects in Patients Suffering From MIH |
Interventional |
Not Applicable
|
Molar Incisor Hypomineralization
|
2019-03-01 |
2020-05-01 |
Ain Shams University |
No
|
| NCT02507921 |
|
|
Resistance in HIV+ in North and South |
Observational |
|
HIV Drug Resistance
|
2015-05-01 |
2015-07-01 |
Infectious Diseases Institute |
No
|
| NCT00215280 |
ZAF
|
DRS Alberts Bouwer & Jordaan Inc; Pretoria;
|
Epidemiology and Control of Mansonella Perstans Infection in Uganda |
Interventional |
Not Applicable
|
Pruritus,Lymphoedema,Mansonelliasis,Abdominal Pains
|
2005-11-01 |
2006-02-01 |
DBL -Institute for Health Research and Development |
No
|
| NCT04861259 |
ZAF, BFA, NGA, Tanzania, South Africa, RWA, GIN, SEN, GAB, EGY, GHA, MOZ, ZMB, TUN, ZWE
|
Louis Pasteur Hospital; Pretoria;
Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS)
Centre de Recherche en Santé de Nouna - Ministère de la Santé; Nouna; (CRSN)
Aminu Kano Teaching Hospital; Kano; (AKTH)
Urban Comprehensive Health Centre; Ile Ife;
Tropical Pesticides Research Institute; Arusha;
University of the Western Cape; Cape Town; (UWC)
Netcare Unitas Hospital; Centurion;
Cardiology Clinical Research; Alberton;
Medicross Medical Centre Vredekloof; Brackenfell;
University of the Free State; Bloemfontein;
Department of Radiotherapy - Addington Hospital; Durban;
Project San Francisco; Kigali;
Centre Hospitalier Régional Spécialisé; Macenta; (CHRS)
Kloof Hospital; Pretoria;
Hospital General De Grand Yoff; Dakar;
Poli Clinic; Port Elizabeth;
Chef du service de parasitologie et de paludisme; Libreville;
Inkosi Albert Luthuli Central Hospital; Durban;
Abu Rish Children's Hospital; Cairo;
Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region;
New Specialist Outpatient Department; Cape Town;
Eugene Park medical Centre; Pretoria;
Intercare Tyger Valley Healthcare Centre; Bellville;
Consultorio Medico Esperanza; Chimoio;
Ragon Institute of MGH, MIT and Harvard and Harvard Global Health Institute -University of KwaZulu Natal; KwaZulu;
St Pauls Mission Hospital; Nchelenge;
Clinique Dermatologique; Dakar;
Worthwhile Clinical Trials - Medinova Merc; Benoni;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Faculty of Medicine - Minia University; El Menia;
Department of Internal Medicine - University of Cape Town; Cape Town;
Instituto Nacional de Saúde; Maputo; (INS)
NESTRA KLINIkAL; Ibadan;
Cancer Centre - Tanta University; Tanta;
Urology and Nephrology Centre - Mansoura University Hospitals; El Bostan;
Netcare Moot General Hospital; Pretoria;
Institut de Rechererch en Science de la Sante; Boulkiemdé;
Service de Rhumatologie-Hôpital La Rabta; Sfax;
University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF)
Red Cross Children's Hospital - University of Cape Town; Cape Town;
Marondera Provincial Hospital; Harare;
Watany Research and Development Center - Watany Eye Hospital; Cairo; (WEH)
|
A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS) |
Interventional |
Phase 3
|
Atypical Hemolytic Uremic Syndrome
|
2021-06-21 |
2027-06-25 |
Hoffmann-La Roche |
No
|
| NCT01565967 |
ZAF
|
Zuid Afrikaanse Hospital; Pretoria;
|
Registry AutoLog Lipid Removal and Blood Component Characterization |
Observational |
|
Trauma
|
2011-12-01 |
2013-03-01 |
Medtronic Bakken Research Center |
No
|
| NCT03378791 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
Efficacy of Iron Bisglycinate in Treatment of Iron Deficiency Anemia in Pregnant Women |
Interventional |
Phase 3
|
Iron Deficiency Anemia of Pregnancy
|
2015-12-31 |
2017-10-31 |
Hatem AbuHashim |
No
|
| NCT03426345 |
ZAF
|
Clinical Research Unit; Gauteng;
Jakaranda Hospital; Pretoria;
Tread Research Cardiology unit of Tygerberg Hospital - University of Stellenbosch; Parow;
|
Study to Evaluate the Safety and Efficacy of Relamorelin in Patients With Diabetic Gastroparesis Study 02 |
Interventional |
Phase 3
|
Gastroparesis,Diabetes Mellitus
|
2018-02-16 |
2020-09-05 |
Allergan |
No
|
| NCT00478738 |
|
|
A 2 Part Study Examining Doses Of GSK961081 In Healthy Volunteers And Then In COPD Patients |
Interventional |
Phase 2
|
Pulmonary Disease, Chronic Obstructive
|
2007-06-01 |
2008-05-01 |
GlaxoSmithKline |
No
|
| NCT04550221 |
ZAF
|
Mamma Clinic; Cape Town;
|
The Shauriana Intervention for GBMSM in Kenya |
Interventional |
Not Applicable
|
HIV Prevention
|
2020-10-28 |
2021-12-15 |
University of Washington |
No
|
| NCT01856478 |
EGY
|
Alexandria University Hospital; Ezbat Saad;
|
LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy |
Interventional |
Phase 3
|
Head and Neck Neoplasms
|
2013-05-23 |
2020-12-31 |
Boehringer Ingelheim |
No
|
| NCT00344071 |
TUN
|
Hospital Charles Nicolle of Tunis; Tunis;
|
Pilot Study of Inflammatory Breast Cancer in Egypt and Tunisia |
Observational |
|
Inflammatory Breast Cancer
|
2004-09-08 |
|
National Cancer Institute (NCI) |
No
|
| NCT04302766 |
ZAF, Uganda, ZMB, BEN, EGY, NGA, Kenya, LBR, GHA
|
Paarl Research Centre; Paarl;
Joint Clinical Research Centre; Lubowa;
Manor Medical Center; Sandton;
Levy Mwanawasa University Teaching Hospital - Levy Mwanawasa Medical University; Lusaka; (LMUTH LMMU)
Mbale Regional Referral Hospital; Mbale;
Medigate Medical Centre; Umhlanga;
Hôpital d'Instruction des Armées Camp Guézo; Cotonou;
Clinical Research Center - Air Force Specialized Hospital; Cairo;
Health Services Department - University of Benin; Benin;
United States Army Medical Research Unit - Kenya; Kombewa; (USAMRU-K)
Fairfield Medical Suites; Clairemont;
Jackson F. Doe Memorial Hospital; Tapeta;
Hiway Medical Center; Durban;
Edenvale Hospital; Edenvale;
Military Hospital; Accra;
Eastern Cape Oncology Center; Port Elizabeth;
|
Expanded Access Remdesivir (RDV; GS-5734™) |
Expanded Access |
|
Coronavirus Disease 2019
|
|
|
U.S. Army Medical Research and Development Command |
No
|
| NCT04237961 |
EGY
|
Assiut University; Assiut;
|
Ancillary Procedures in Patients of Refractory Facial Palsy Patients Selection and Evaluation of the Outcomes |
Interventional |
Not Applicable
|
Facial Palsy
|
2019-01-01 |
2020-03-28 |
Assiut University |
No
|
| NCT03314701 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Mechanical Ventilation in Multiple Fracture Ribs |
Interventional |
Not Applicable
|
Mechanical Ventilation
|
2017-10-25 |
2018-12-01 |
Assiut University |
No
|
| NCT00244725 |
|
|
Odiparcil For The Prevention Of Venous Thromboembolism |
Interventional |
Phase 2
|
Pulmonary Embolism,Deep Vein Thrombosis,Fibrillation, Atrial,Venous Thromboembolism
|
2005-09-01 |
2006-09-01 |
GlaxoSmithKline |
No
|
| NCT04012931 |
Uganda, South Africa
|
Joint Clinical Research Centre; Lubowa;
JOSHA Research; Bloemfontein;
|
A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed |
Interventional |
Phase 2
|
HIV
|
2019-07-18 |
2023-02-09 |
Janssen Research & Development, LLC |
No
|
| NCT04128540 |
|
|
Erector Spinae Plane Block Versus Fentanyl Infusion in Pediatric Patients Undergoing Aortic Coarcitectomy |
Interventional |
Phase 4
|
Paediatric,Aortic Coarctation,Erector Spinae Plane Block
|
20-02-01 |
20-07-01 |
Cairo University |
No
|
| NCT04688996 |
MDG
|
Institute Pasteur de Madagascar; Antananarivo;
|
Yersinia Pestis Lateral Flow Immunoassay. |
Observational |
|
Plague,Plague, Bubonic,Yersinia Sepsis,Pneumonic Plague,Plague, Pneumonic,Bubo; Yersinia Pestis,Bubonic; Plague, Skin,Yersinia Pestis; Bubo,Yersinia Pestis Plague,Yersinia Pestis Infection,Yersinia Pestis; Pneumonia
|
2020-10-19 |
2022-11-01 |
Brimrose Technology Corporation |
No
|
| NCT02272413 |
ZAF, EGY
|
Langenhoven Drive Oncology Centre; Port Elizabeth;
Oncology Centre - Mansoura University Hospitals; Mansoura;
Alexandria University Hospital; Ezbat Saad;
Rondebosch Oncology Centre - CancerCare; Cape Town;
Outeniqua GVI Oncology; George;
|
Phase III Trial BI 695502 Plus Chemotherapy vs. Avastin® Plus Chemotherapy in Patients With Lung Cancer |
Interventional |
Phase 3
|
Carcinoma, Non-Small-Cell Lung
|
2015-07-08 |
2018-11-16 |
Boehringer Ingelheim |
No
|
| NCT04260685 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Lidocaine Versus Esmolol for Optimizing Surgical Field Visibility |
Interventional |
Phase 2
|
Lumbar Disc Herniation
|
2020-02-04 |
2020-06-30 |
Zagazig University |
No
|
| NCT00096824 |
South Africa
|
University of Witwatersrand; Johannesburg;
|
A Study of Dementia and Neurological Problems in HIV Infected Patients Who Are Participating in ACTG A5175 |
Observational |
|
HIV Infections
|
2006-02-01 |
2010-05-01 |
AIDS Clinical Trials Group |
No
|
| NCT04556981 |
ZAF, Ghana, South Africa
|
Wits RHI Shandukani Research Centre CRS; Johannesburg; (RHI)
Africa Health Research Institute; Durban;
The Aurum Institute Ghana; Accra;
Desmond Tutu HIV Foundation; Cape Town;
|
Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV |
Interventional |
Phase 2
|
Human Immunodeficiency Virus
|
2020-11-17 |
2022-07-01 |
Bill & Melinda Gates Medical Research Institute |
No
|
| NCT03225794 |
CMR
|
Centre Pasteur du Cameroun; Yaoundé; (CPC)
|
Simian Foamy Virus Transmission to Humans |
Observational |
|
Simian Foamy Virus Infection (Disorder)
|
2010-11-01 |
2020-10-01 |
Institut Pasteur |
No
|
| NCT01380080 |
ZAF
|
Soweto ACTG CRS; Johannesburg;
|
REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment |
Interventional |
Phase 4
|
HIV Infection
|
2011-10-01 |
2016-04-01 |
AIDS Clinical Trials Group |
No
|
| NCT04736316 |
ZAF
|
Edenvale Hospital; Edenvale;
|
Early Community Client-LED ART Delivery in Nakivale Refugee Settlement |
Interventional |
Not Applicable
|
HIV Seropositivity
|
2020-06-29 |
2021-12-31 |
University of Washington |
No
|
| NCT00931463 |
South Africa, NGA
|
JOSHA Research; Bloemfontein;
Federal Medical Center; Owo; (FMCOWO)
Desmond Tutu HIV Foundation; Cape Town;
|
A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen |
Interventional |
Phase 4
|
HIV Infections
|
2009-09-01 |
2013-08-01 |
Kirby Institute |
No
|
| NCT03853460 |
MLI, EGY
|
Faculty of Medicine - University of Bamako; Bamako;
Assiut University; Assiut;
|
Bilateral Quadraus LUMBORUM Block in Patients Under Going Cystectomy |
Interventional |
Not Applicable
|
Pain, Acute
|
2019-10-30 |
2020-12-30 |
Assiut University |
No
|
| NCT04048551 |
ZAF
|
Setshaba Research Centre; Soshanguve; (SRC)
|
The PrEPARE Project: Prevention, Empowering, and Protecting Young Women in South Africa |
Interventional |
Not Applicable
|
HIV Prevention
|
2019-04-04 |
2022-08-30 |
RTI International |
No
|
| NCT04266145 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
Intravenous Versus Perineural Dexmedetomidine as Adjuvant in Adductor Canal Block for Total Knee Arthroplasty |
Interventional |
Not Applicable
|
Post Spinal Anesthesia Shivering
|
2020-02-29 |
2020-12-31 |
Mansoura University |
No
|
| NCT04401878 |
EGY
|
Faculty of Medicine - Zagazig University; Zagazig;
|
Verification of SGB in Management of Patients With PDPH Using TCD |
Interventional |
Not Applicable
|
Post-Dural Puncture Headache
|
2019-10-04 |
2020-05-30 |
Zagazig University |
No
|
| NCT01063062 |
|
|
A Study With Tocilizumab [RoActemra/Actemra] Monotherapy or in Combination With Methotrexate in Patients With Rheumatoid Arthritis (PICTURE) |
Interventional |
Phase 3
|
Rheumatoid Arthritis
|
2010-02-28 |
2011-01-17 |
Hoffmann-La Roche |
No
|
| NCT03920163 |
|
|
Enhanced Recovery After Trauma Surgery |
Interventional |
Not Applicable
|
Penetrating Abdominal Trauma
|
2019-03-29 |
2021-12-31 |
University of Cape Town |
No
|
| NCT01721798 |
|
|
Comparison of Two IUDs Among Cape Town HIV-positive Women |
Interventional |
Not Applicable
|
HIV
|
2013-11-10 |
2018-07-13 |
FHI 360 |
No
|
| NCT02199951 |
Ghana
|
Kintampo Health Research Centre; Kintampo; (KHRC)
|
Introduction of Eurartesim® in Burkina Faso, Mozambique, Ghana and Tanzania |
Observational |
|
Malaria
|
2013-09-01 |
2014-12-01 |
INDEPTH Network |
No
|
| NCT00490230 |
TUN
|
Institut Pasteur de Tunis; Tunis;
|
Cosmetic Outcome of Leishmaniasis Scar After WR279396 Application |
Interventional |
Not Applicable
|
Scar,Cutaneous Leishmaniasis
|
2007-04-01 |
2007-06-01 |
U.S. Army Medical Research and Development Command |
No
|
| NCT03671109 |
Mozambique
|
Centro de Investigação em Saúde de Manhiça; Manhica; (CISM)
|
Improving Maternal heAlth by Reducing Malaria in African HIV Women |
Interventional |
Phase 3
|
Malaria,HIV/AIDS,Pregnancy Related
|
2019-09-20 |
2022-11-01 |
Barcelona Institute for Global Health |
No
|
| NCT03749395 |
EGY
|
Banha University Hospital; Qalyoubia;
|
Ultrasound Guided Erector Spinae Block for Postoperative Analgesia in Thoracotomy Patients |
Interventional |
Not Applicable
|
Postoperative Pain
|
2018-12-05 |
2019-11-05 |
Benha University |
No
|
| NCT00811421 |
TZA, Mozambique
|
Ifakara Health Institute; Dar es Salaam;
Centro de Investigação em Saúde de Manhiça; Manhica; (CISM)
|
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy |
Interventional |
Not Applicable
|
Malaria,Pregnancy,HIV Infections
|
2009-09-01 |
2013-12-01 |
Hospital Clinic of Barcelona |
No
|
| NCT04889040 |
ZAF, BWA, UGA, BEN, NGA, South Africa, AGO, Uganda, GHA, RWA, EGY, TUN, SEN, DZA, COD, MOZ, ETH, KEN, ZMB, CIV, BFA, NAM, CAF, ZWE, MLI, Mozambique, Tanzania
|
Medforum Mediclinic; Pretoria;
Francistown Academic Hospital; Francistown;
Jooste Hospital; Cape Town;
Department of Haematology and Cell Biology - University of the Free State; Bloemfontein;
Kasangati Health Center IV; Wakiso;
Sanofi-Aventis Administrative Office; Midrand;
Centre de Diagnostic et de Traitement de la Tuberculose de Kandi; Kandi;
Iatros International; Bloemfontein;
Urban Comprehensive Health Centre; Ile Ife;
Synexus Stanza Clinical Research Centre; Mamelodi;
Instituto de Combate e Controlo das Tripanossomiases; Luanda; (ICCT)
Clinical Projects Research; Worcester;
Allergology Diagnostic Clinical Research Centre; Western Cape; (ADCRU)
City Park Medical Centre; Cape Town;
Infectious Diseases Institute; Kampala; (IDI)
Netcare Unitas Hospital; Centurion;
Korle Bu Teaching Hospital; Accra;
Manor Medical Center; Sandton;
Kopong Health Clinic; Kopong;
Cardiology Clinical Research; Alberton;
Department of Radiotherapy - Addington Hospital; Durban;
Project San Francisco; Kigali;
EgyBrit Medical Centre; Cairo;
Universitas Private Hospital; Bloemfontein;
College of Medicine - University of Lagos; Lagos;
Task Eden Clinical Research Centre; George;
Verulam CRS; Durban;
Mbale Regional Referral Hospital; Mbale;
Polyclinique Taoufik; Tunis;
Scion Clinical Research; Pretoria;
Cooper University Hospital Clinical Research Site; Durban;
Hospital General De Grand Yoff; Dakar;
Irrua Specialist Teaching Hospital; Edo;
Western Cape Clinical Trials; Western Cape;
Independence Surgery; Gaborone;
Centre for Malaria Research and Phytomedicine - University of Port Harcourt; Port Harcourt;
Poli Clinic; Port Elizabeth;
Centre Hospitalo-Universitaire de Tizi Ouzou; Tizi Ouzou; (CHU)
Centre Hospitalier du Mont-Amba; Kinshasa;
Practice Prof. Y Elhawary - AlSalama Hospital; Cairo;
Polana Caniço Health Research and Training Center - Instituto Nacional de Saúde and Ministry of Health; Cidade de Maputo; (CISPOC)
Hopital Frantz Fanon; Béjaïa;
New Specialist Outpatient Department; Cape Town;
Center for Clinical Care and Clinical Research; Abuja; (CCCRN)
Centre de Pneumo-Phthysiologie; Cotonou;
Clinical Research Center - Agaro General Hospital; Agaro; (CRC)
Intercare Tyger Valley Healthcare Centre; Bellville;
Centre de Diagnostic et de Traitement de la Tuberculose de Comè; Comè;
Consultorio Medico Esperanza; Chimoio;
Kisumu County Hospital; Kisumu;
Meulmed Hospital; Pretoria;
St Pauls Mission Hospital; Nchelenge;
Cocody University Hospital Center; Abidjan;
NHC Health Center; Randburg;
Hospital Aziza Othmana; Tunis;
Winelands Medical Research Centre; Cape Winelands;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
Medicross Saxby Medical Centre; Centurion;
Galaa Military Hospital; Heliopolis;
Tara Hospital; Cape Town;
Centre médical Paul VI; Ouagadougou;
Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH)
Centre Hospitalo-Universitaire Saadna Abdenour de Setif; Setif; (CHU)
Mercantile Private Hospital - Life Healthcare; Port Elizabeth;
Albert Alberts Stem Cell Transplant Centre; Pretoria;
Infectious and Tropical Diseases Department - Fann Hospital; Dakar;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Faculty of Medicine - Minia University; El Menia;
East Central Hospital; Windhoek;
Institut Pasteur de Bangui; Bangui;
University Hospital Freiburg and Johannesburg Hospital; Johannesburg;
Hospital Central de l'Armée; Algiers;
Ethiopian Public Health Association; Addis Ababa;
Service de Rhumatologie - Hospital Charles Nicolle of Tunis; Tunis;
Hiway Medical Center; Durban;
Instituto Nacional de Saúde; Maputo; (INS)
Ophthalmological Clinic Cairo Retina Center - Magdy Hospital; Giza;
NESTRA KLINIkAL; Ibadan;
Emery Clinical Services; Alberton;
Tembisa Clinic 4 CoVPN CRS; Tembisa;
Nariman Public Hospital; Bab Sharq-Wabour El Meiah;
Cancer Centre - Tanta University; Tanta;
Beatrice Road Infectious Diseases Hospital; Harare;
Netcare N1 City Hospital; Cape Town;
Clinique des Halles - Association de Recherche de Communication et d’Accompagnement à Domicile de personnes Vivant avec le vih; Bamako; (ARCAD-SIDA)
Helen Joseph Hospital; Johannesburg;
Africa International Research; Cape Town;
Netcare Moot General Hospital; Pretoria;
Centro de Investigação em Saúde de Manhiça; Manhica; (CISM)
Military Hospital; Accra;
Centre for Infectious and Parasitic Diseases Control Research - Kenya Medical Research Institute; Busia; (CIPDCR-KEMRI)
Bertoni Mercy Clinic; Pretoria;
Mathare North City Clinic; Nairobi;
Mwanza Research Centre - National Institute for Medical Research; Mwanza; (MRC NIMR)
Panaroma Medical Centre; Parow;
Marondera Provincial Hospital; Harare;
|
Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19 |
Interventional |
Phase 3
|
COVID-19
|
2021-04-28 |
2021-08-03 |
Atea Pharmaceuticals, Inc. |
Yes
|
| NCT04665791 |
|
|
A Human Controlled Infection Study With Neisseria Lactamica in Malian Adults |
Interventional |
Not Applicable
|
Meningitis, Meningococcal
|
2021-03-02 |
2023-01-01 |
Center for Vaccine Development - Mali |
No
|
| NCT01469520 |
NGA
|
Bowen University Teaching Hospital; Ogbomoso; (BUTH)
|
Bioequivalence Study of Pediatric Formulations to Treat HIV Infection |
Interventional |
Phase 1
|
HIV,AIDS
|
2010-10-01 |
2011-12-01 |
Elim Pediatric Pharmaceuticals Inc. |
No
|
| NCT00615264 |
ZAF
|
Centre for Diabetes and Endocrinology; Johannesburg;
Wits Donald Gordon Medical Centre; Johannesburg; (WDGMC)
|
Efficacy Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Patients |
Interventional |
Phase 3
|
Type 1 Diabetes
|
2005-09-01 |
2012-01-01 |
Andromeda Biotech Ltd. |
No
|
| NCT02605395 |
|
|
Bioequivalence Study of Raperazole 20mg DR Tabs and PARIET® 20 mg DR Tabs Under Fed Conditions |
Interventional |
Phase 4
|
Gastrointestinal Diseases
|
2014-03-22 |
2014-03-30 |
GlaxoSmithKline |
No
|
| NCT00371735 |
|
|
Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria |
Interventional |
Phase 3
|
Malaria, Falciparum
|
2006-04-01 |
2007-05-01 |
GlaxoSmithKline |
No
|
| NCT04240548 |
|
|
Radiation Therapy for ypN0 Breast Cancer |
Interventional |
Phase 3
|
Breast Cancer
|
2016-01-01 |
2023-12-31 |
National Cancer Institute, Egypt |
No
|
| PACTR201906515532827 |
NGA
|
Murtala Muhammad Specialist Hospital; Kano;
|
Effect of Paula Exercise Method on Functional Outcomes Among Women Having Post Fistula Repair Incontinence: A randomised controlled trial |
RCT |
|
Obstetrics and Gynecology
|
70-01-01 |
70-01-01 |
Alsauda Global Investment |
No
|
| NCT00617175 |
ZAF
|
Netcare Unitas Hospital; Centurion;
Netcare Christiaan Barnard Memorial Hospital; Cape Town;
Vincent Pallotti Hospital; Pinelands;
Milpark Hospital; Johannesburg;
|
Avoid DeliVering TherApies for Non-sustained Arrhythmias in ICD PatiEnts III |
Interventional |
Phase 4
|
Heart Disease
|
2008-03-01 |
2012-02-01 |
Medtronic Bakken Research Center |
No
|
| NCT00988507 |
BEN
|
Sanofi-Aventis Investigational Site Number 204001; Cotonou;
|
Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria |
Interventional |
Phase 2
|
Plasmodium Falciparum Infection
|
2009-10-01 |
2010-11-01 |
Sanofi |
No
|
| NCT00351169 |
ZAF
|
Groote Schuur Clinical Research Site; Cape Town;
|
Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder |
Interventional |
Phase 3
|
Major Depressive Disorder
|
2006-05-01 |
2007-06-01 |
AstraZeneca |
No
|
| NCT00224497 |
|
|
A Dose Ranging Study To Investigate The Efficacy And Safety Of SB-742457 In Alzheimer's Disease |
Interventional |
Phase 2
|
Alzheimer's Disease
|
2005-09-01 |
|
GlaxoSmithKline |
No
|
| NCT00182819 |
|
|
Radiation Therapy or Temozolomide in Treating Patients With Gliomas |
Interventional |
Phase 3
|
Brain and Central Nervous System Tumors
|
2005-07-01 |
2014-05-01 |
European Organisation for Research and Treatment of Cancer - EORTC |
No
|
| NCT02053038 |
EGY
|
15th of May Hospital; Cairo;
|
Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation |
Interventional |
Not Applicable
|
Coronary Artery Disease
|
2014-01-01 |
2021-01-19 |
Imperial College London |
No
|
| NCT00915018 |
ZAF
|
Eastleigh Breast Care Centre; Pretoria;
|
Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast Cancer |
Interventional |
Phase 2
|
Breast Cancer
|
2009-08-21 |
2018-06-28 |
Puma Biotechnology, Inc. |
No
|
| NCT02409290 |
ZAF
|
Helen Joseph Hospital; Johannesburg;
|
The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB |
Interventional |
Phase 3
|
MDR-TB
|
2016-04-01 |
2022-07-01 |
IUATLD, Inc |
No
|
| NCT04784715 |
ZAF
|
Groote Schuur Clinical Research Site; Cape Town;
|
Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09) |
Interventional |
Phase 3
|
Breast Cancer; HER2-positive; Metastatic
|
2021-04-26 |
2029-12-30 |
AstraZeneca |
No
|
| NCT02293863 |
ZAF
|
Clinical Projects Research; Worcester;
Milpark Hospital; Johannesburg;
|
A Study of MHAA4549A in Combination With Oseltamivir Versus Oseltamivir in Participants With Severe Influenza A Infection |
Interventional |
Phase 2
|
Influenza
|
2015-01-14 |
2017-05-23 |
Genentech, Inc. |
No
|
| NCT03366545 |
ZAF
|
Gateway Private Hospital; Kwazulu Natal;
Netcare Unitas Hospital; Centurion;
|
Observation of Clinical Routine Care for Heart Failure Patients Implanted With BIOTRONIK CRT Devices |
Observational |
|
Heart Failure
|
2018-05-14 |
2025-06-01 |
Biotronik SE & Co. KG |
No
|
| NCT00076804 |
|
|
Helping HIV Infected Patients in South Africa Adhere to Drug Regimens |
Interventional |
Phase 2
|
HIV Infections
|
2005-02-01 |
2008-09-01 |
Johns Hopkins University |
No
|
| NCT03269786 |
EGY
|
Assiut University; Assiut;
|
Changes in Lab and Ultrasonography After Endoscopic Varisceal Treatment |
Observational |
|
Liver Cirrhosis
|
2018-11-01 |
2019-11-01 |
Assiut University |
No
|
| NCT01848730 |
ZAF
|
Netcare Christiaan Barnard Memorial Hospital; Cape Town;
|
Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Post-herpetic Neuralgia |
Interventional |
Phase 2
|
Post-herpetic Neuralgia
|
2013-04-01 |
2014-05-01 |
Convergence Pharmaceuticals |
No
|
| NCT04501978 |
BWA, MWI, ZAF, BFA, BEN, Uganda, SLE, RWA, NGA, EGY, SEN, KEN, UGA, MOZ, MAR, TZA, TUN, LBR, ZWE, DZA
|
Francistown Academic Hospital; Francistown;
Malawi College of Medicine - John Hopkins Bloomberg School of Public Health; Blantyre;
Queenswood CTC; Pretoria;
Investigational Site Number 2040001; Cotonou;
Sanofi-Aventis Investigational Site Number 204001; Cotonou;
Louis Pasteur Hospital; Pretoria;
Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS)
Clinical Projects Research; Worcester;
Cape Trial Centre; Bellville;
Infectious Diseases Institute; Kampala; (IDI)
Manor Medical Center; Sandton;
University Of Dakar; Dakar;
College of Medicine and Allied Health Sciences - Connaught Hospital; Freetown; (COMAHS)
Project San Francisco; Kigali;
College of Medicine - University of Lagos; Lagos;
Catholic Caritas Foundation; Abuja;
Stikland Hospital; Cape Town;
Boland Ethical Research Group; Western Cape;
Mbale Regional Referral Hospital; Mbale;
The Urology Hospital; Pretoria;
Cooper University Hospital Clinical Research Site; Durban;
15th of May Hospital; Cairo;
Niakhar Demographic Surveillance System; Dakar;(DS IDR)
Southern Cross Hospital; Cape Town;
Institut Pasteur; Dakar;
Eastern and Southern Africa Centre of International Parasite Control - Kenya Medical Research Institute; Nairobi; (ESACIPAC-KEMRI)
Richards Bay Trial Center - Bay Hospital; KwaZulu Natal;
Baylor Uganda Clinical Research Sites; Kampala; (CRS)
Polana Caniço Health Research and Training Center - Instituto Nacional de Saúde and Ministry of Health; Cidade de Maputo; (CISPOC)
Ibn Rochd University Hospital; Casablanca;
Immanuel General Hospital; Eket;
Intercare Tyger Valley Healthcare Centre; Bellville;
Netcare Christiaan Barnard Memorial Hospital; Cape Town;
Department of cardiology - Military hospital Marrakech; Marrakech;
Hôpital de Fann; Dakar;
George Clinical Study Site; George;
Consultorio Medico Esperanza; Chimoio;
MRC/UVRI & LSHTM Uganda Research Unit; Entebbe;
PAREXEL Port Elizabeth; Port Elizabeth;
University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC)
National Heart Institute; Giza;
Winelands Medical Research Centre; Cape Winelands;
Pretoria Heart Hospital; Pretoria;
Department of Medical Microbiology Parasitology - College of Medicine University of Ibadan; Oyo;
St. James's Hospital Life Health; East London;
Health Services Department - University of Benin; Benin;
National Institute for Medical Research; Tanga;
Infectious and Tropical Diseases Department - Fann Hospital; Dakar;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Lions SightFirst Hospital; Nairobi;
Jackson F. Doe Memorial Hospital; Tapeta;
South Valley University; Qena;
Hiway Medical Center; Durban;
Kimberley Hospital Complex; Kimberley;
Medicross Bluff Medical Center; Durban;
Beatrice Road Infectious Diseases Hospital; Harare;
Intercare Medical and Dental Centre; Lynwood;
Skin Avenue Clinic; El Salam El Sharkaia;
ELWA Medical Center; Monrovia;
Damien Foundation; Abuja;
Mont Amba Medical Center - University of Kinshasa; Lemba;
Hôpital de rouiba; Rouïba;
University of California San Francisco - Kenya Medical Research Institute; Kisumu; (UCSF-KEMRI)
Bishop Lavis Day Hospital; Cape Town;
Medical Suite M23; Pretoria;
Infectious Diseases Research Collaboration; Tororo;
|
ACTIV-3: Therapeutics for Inpatients With COVID-19 |
Interventional |
Phase 3
|
Covid19
|
2020-08-04 |
2022-07-01 |
National Institute of Allergy and Infectious Diseases (NIAID) |
Yes
|
| NCT00397722 |
|
|
Treatment Of Patients With Social Anxiety Disorder |
Interventional |
Phase 2
|
Social Phobia
|
2006-11-09 |
2007-09-05 |
GlaxoSmithKline |
No
|
| NCT04841291 |
ETH
|
Maksegnit Clinical Trial Site - University of Gondar; Amhara;
|
Feasibility of Virtual Simulation-Based Diabetes Foot Care Education in Patients With Diabetes in Ethiopia |
Interventional |
Not Applicable
|
Diabetes Foot Care
|
2021-04-20 |
2021-07-30 |
Queen's University |
No
|
| NCT03087097 |
|
|
Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition |
Interventional |
Phase 1
|
Severe Acute Malnutrition,Moderate Acute Malnutrition
|
2019-04-11 |
2020-07-21 |
Microbiome Health Research Institute |
No
|
| NCT02768376 |
|
|
Spinal for Laparoscopic Cholecystectomy |
Interventional |
Not Applicable
|
Laparoscopic Cholecystectomy
|
2016-03-01 |
2017-10-01 |
Mansoura University |
No
|
| NCT00108862 |
ZAF
|
Soweto ACTG CRS; Johannesburg;
|
Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis |
Interventional |
Phase 4
|
Tuberculosis,HIV Infection
|
2006-08-01 |
2010-07-01 |
AIDS Clinical Trials Group |
No
|
| NCT03283475 |
EGY
|
Assiut University; Assiut;
|
Different Surgical Modalities for Thigh Lipodystrophy Including Liposuction,Thigh Lift and Liposuction Assisted Thigh Lift |
Interventional |
Not Applicable
|
Thigh Lipodystrophy
|
2017-05-14 |
2019-04-01 |
Assiut University |
No
|
| NCT04382053 |
EGY
|
Investigator Clinic; Giza;
|
Study of Efficacy and Safety of DV890 in Patients With COVID-19 Pneumonia |
Interventional |
Phase 2
|
COVID 19 Pneumonia, Impaired Respiratory Function
|
2020-05-27 |
2020-12-24 |
Novartis Pharmaceuticals |
Yes
|
| NCT03658590 |
EGY
|
Ain Shams University; Cairo;
|
Dexamethasone and Induction of Delivery |
Interventional |
Phase 1
|
Induction of Labor Affected Fetus / Newborn
|
2018-01-01 |
2018-06-30 |
samar sayed el sayed |
No
|
| NCT02298140 |
TZA
|
Ifakara Health Institute; Dar es Salaam;
|
Providers' Compliance to Malaria Treatment |
Interventional |
Not Applicable
|
Malaria
|
2014-11-01 |
2015-12-01 |
Ifakara Health Institute |
No
|
| NCT04285177 |
|
|
Choroidal and Retinal Thickness Following Strabismus Surgery |
Observational |
|
Strabismus,Retinal Thickening
|
2020-02-15 |
2020-12-01 |
Tanta University |
No
|
| NCT03765073 |
ZAF
|
Reproductive Health and HIV Institute - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS RHI)
Khayelitsha Hospital; Khayelitsha;
|
Trial To Evaluate The Safety, Tolerability, And Immunogenicity Of A Multivalent Group B Streptococcus Vaccine In Healthy Nonpregnant Women And Pregnant Women And Their Infants |
Interventional |
Phase 2
|
Group B Streptococcus Infections
|
2019-01-14 |
2022-12-27 |
Pfizer |
No
|
| NCT02413580 |
|
|
A Study to Assess the Efficacy and Safety of IGIV-C in Patients With Myasthenia Gravis Exacerbations |
Interventional |
Phase 3
|
Myasthenia Gravis Exacerbations
|
2015-03-01 |
2018-04-01 |
Grifols Therapeutics LLC |
No
|
| NCT04406168 |
EGY
|
Assiut University; Assiut;
|
Assessment of Urinary Diversions Outcomes Post Radical Cystectomy in Asyut University Urology Hospital |
Observational |
|
Bladder Cancer
|
2020-06-01 |
2023-05-01 |
Assiut University |
No
|
| NCT01542710 |
|
|
Bimatoprost/Timolol Versus Travoprost/Timolol |
Interventional |
Not Applicable
|
Glaucoma
|
2011-01-01 |
2011-12-01 |
Kasr El Aini Hospital |
No
|
| NCT00045032 |
ZAF, TUN
|
Netcare Pretoria East Hospital; Pretoria;
Hospital Militaire; Montfleury;
|
Herceptin (Trastuzumab) in Treating Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Primary Breast Cancer |
Interventional |
Phase 3
|
Breast Cancer
|
2001-11-01 |
2015-06-01 |
Hoffmann-La Roche |
No
|
| NCT02139956 |
EGY
|
Ain Shams University; Cairo;
|
Assessment of the Internal Urethral Sphincter and the Vagina by Three Dimensional Ultrasound |
Observational |
|
Urinary Incontinence Due to Urethral Sphincter Incompetence
|
2014-05-01 |
|
Ain Shams University |
No
|
| NCT03258125 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9 |
Observational |
|
Preeclampsia
|
2019-01-01 |
2020-06-01 |
Assiut University |
No
|
| NCT00303576 |
ZAF
|
Farmovs Intergrated Research Solutions; Bloemfontein;
|
A Safety and Tolerability Study of Dapivirine (TMC120) Vaginal Microbicide Gel |
Interventional |
Phase 1,Phase 2
|
HIV Infections
|
2005-10-01 |
2006-07-01 |
International Partnership for Microbicides, Inc. |
No
|
| NCT01197027 |
MWI
|
Kamuzu Central Hospital; Lilongwe;
|
Feasibility and Acceptability Study of an Individual-Level Behavioral Intervention for Individuals With Acute and Early HIV-Infection |
Interventional |
Phase 3
|
Acute HIV Infection
|
2010-02-01 |
2012-04-01 |
HIV Prevention Trials Network |
No
|
| NCT01369095 |
EGY, ZAF, NGA, TZA, RWA, UGA, NAM, Burkina Faso
|
Clinical Research Center - Cairo University; Giza;
Mansoura University Hospitals; Mansoura;
Neurology Department - Groote Schuur Hospital; Cape Town;
Urban Comprehensive Health Centre; Ile Ife;
Clinical Research Unit; Cosmo; (LCS)
Ifakara Health Research and Development Center; Dar es Salaam;
Arthritis Clinical Research Trials; Cape Town;
Africa Health Research Institute; Durban;
Boland Ethical Research Group; Western Cape;
Global Clinical Trials; Pretoria;
Scion Clinical Research; Pretoria;
Western Cape Clinical Trials; Western Cape;
Project San Francisco - Emory University; Kigali;
Vista Clinic; Centurion;
Baylor Uganda Clinical Research Sites; Kampala; (CRS)
Center for Clinical Care and Clinical Research; Abuja; (CCCRN)
Drs Gudgeon and Boeddinghaus Associates; Cape Town;
George Clinical Study Site; George;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
Genelin Clinical Trials; Free State;
National Institute for Medical Research; Tanga;
Dr Rory Callaghan Inc; Durban;
Medical Research Council Uganda Virus Research Institute Research Unit on AIDS; Entebbe;
Faculty of Medicine - Minia University; El Menia;
RK Khan Hospital; Durban;
The Behman Hospital; Cairo;
Institute of Psychiatry - Ain Shams University; Cairo;
Think TB and HIV Investigative Network; Durban;
Netcare Moot General Hospital; Pretoria;
Medical Centre; Erongo;
Damien Foundation; Abuja;
Centre National de la Recherche Scientifique et Technologique - Institut de Recherche en Science de la Santé; Ouagadougou; (CNRST IRSS)
|
Efficacy and Safety of Fixed Doses of BMS 820836 in the Treatment of Patients With Treatment Resistant Major Depression |
Interventional |
Phase 2
|
Depression
|
2011-07-01 |
2013-05-01 |
Bristol-Myers Squibb |
No
|
| NCT04729413 |
GHA
|
Hohoe Health Research Centre; Volta;
|
Happy Homes, Healthy Families: A Relationship Strengthening Intervention for Pregnant Couples Affected by HIV in Zambia |
Interventional |
Not Applicable
|
HIV Infections,Pregnancy Related
|
2020-12-19 |
2023-04-01 |
University of Colorado, Denver |
No
|
| NCT02943135 |
EGY
|
Assiut University; Assiut;
|
Lidocaine In-situ Gel Before Intrauterine Device Insertion |
Interventional |
Phase 3
|
Pain Relief
|
2017-10-01 |
2020-03-30 |
Assiut University |
No
|
| NCT02687373 |
Kenya
|
Centre for Global Health Research - Kenya Medical Research Institute; Kisumu; (CGHR-KEMRI)
|
Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya |
Interventional |
Phase 1,Phase 2
|
Malaria
|
2016-07-21 |
2018-08-14 |
Sanaria Inc. |
No
|
| NCT00642148 |
|
|
A 12 Week Study To Assess Efficacy And Safety Of GW856553 In Subjects With Chronic Obstructive Pulmonary Disease (COPD) |
Interventional |
Phase 2
|
Pulmonary Disease, Chronic Obstructive
|
2008-02-14 |
2009-07-27 |
GlaxoSmithKline |
No
|
| NCT00146380 |
|
|
A Study of Zidovudine/Lamivudine and Either Nevirapine or Nelfinavir for Reduction of Mother-to-child HIV Transmission During Breastfeeding |
Interventional |
Phase 2
|
HIV Infections
|
2003-07-01 |
2013-01-01 |
Centers for Disease Control and Prevention |
No
|
| NCT04344522 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Descemet Membrane Endothelial Keratoplasty Combined With Intraocular Lens Exchange: Sequential Versus Combined Surgery |
Interventional |
Not Applicable
|
Pseudophakic Bullous Keratopathy,Anterior Chamber Intraocular Lens
|
2020-08-11 |
2021-11-01 |
Alexandria University |
No
|
| NCT04374513 |
EGY
|
Damanhour University; Damanhur
|
Community Pharmacists Behaviour During Covid-19 |
Observational |
|
Covid19
|
2020-05-02 |
2021-04-01 |
Damanhour University |
Yes
|
| NCT02618707 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Lactate Levels During Cardiopulmonary Bypass in Pediatric Patients |
Observational |
|
Heart Defects, Congenital
|
2015-12-01 |
2016-03-01 |
Assiut University |
No
|
| NCT03927313 |
|
|
Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBM |
Interventional |
Phase 2
|
HIV-1-infection,Tuberculosis Meningitis
|
2019-06-12 |
2020-12-31 |
University of Cape Town |
No
|
| NCT00151892 |
ZAF
|
Mamma Clinic; Cape Town;
Milpark Hospital; Johannesburg;
|
Efficacy and Safety of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis |
Interventional |
Phase 3
|
Ulcerative Colitis
|
2005-04-08 |
2009-09-07 |
Shire |
No
|
| NCT00541385 |
|
|
Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients |
Interventional |
Phase 3
|
Malaria
|
2007-10-01 |
2008-11-01 |
Medicines for Malaria Venture |
No
|
| NCT02785510 |
EGY
|
National Liver Institute; Menofia;
|
Determining Clinical Profile of Parkinson's Disease Among Egyptian Population |
Observational |
|
Parkinson's Disease
|
2017-08-01 |
2018-12-31 |
Zagazig University |
No
|
| NCT03049176 |
ZWE
|
Zengeza Clinical Research Site - University of Zimbambwe Colege ofHealth Sciences Clinical Trials Research Centre; Harare; ( UZCHS- UCSFCTRC)
|
The Impact and Cost-effectiveness of Safer Conception Strategies for HIV-discordant Couples (SAFER) |
Observational |
|
HIV Infections
|
2017-03-13 |
2019-07-31 |
University of California, San Francisco |
No
|
| NCT04214379 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Management of Severe Congenital Blepharoptosis |
Interventional |
Not Applicable
|
Blepharoptosis
|
2017-02-01 |
2018-09-17 |
Minia University |
No
|
| NCT04221477 |
ZAF
|
Manor Medical Center; Sandton;
|
A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis |
Interventional |
Phase 3
|
Lupus Nephritis
|
2020-08-10 |
2028-04-18 |
Hoffmann-La Roche |
No
|
| NCT00843193 |
|
|
Efficacy and Safety Study of GSK679586 in Patients With Severe Asthma |
Interventional |
Phase 2
|
Asthma
|
2008-12-09 |
2010-07-25 |
GlaxoSmithKline |
No
|
| NCT04810650 |
ZMB, UGA
|
Choma District Health Office; Choma;
Uganda Virus Research Institute; Entebbe;
|
A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa |
Interventional |
Not Applicable
|
HIV,Hypertension,Alcohol Drinking,Cost Effectiveness,Adolescent Behavior,Maternal Child Health
|
2021-04-15 |
2023-09-01 |
University of California, San Francisco |
No
|
| NCT03546179 |
EGY
|
National Liver Institute; Menofia;
|
Tidal Volume Challenge and Reliability of Plethysmography Variability Index |
Observational |
|
Abdominal Cancer
|
2018-08-01 |
2020-02-15 |
Fayoum University Hospital |
No
|
| NCT03306004 |
NGA
|
Bowen University Teaching Hospital; Ogbomoso; (BUTH)
|
Neonatal Jaundice: Knowledge, Attitudes and Practices of Mothers and Medical Trainees and Providers in and Around Ogbomosho |
Observational |
|
Neonatal Jaundice
|
2016-11-01 |
2017-12-31 |
University of Minnesota |
No
|
| NCT02028013 |
ZAF
|
Mamma Clinic; Cape Town;
|
Management of Sexual Dysfunction With Bioresonance Technique |
Observational |
|
Sexual Dysfunction,Erectile Dysfunction,Premature Ejaculation
|
2013-01-01 |
2016-08-01 |
Man Clinic for Andrology, Male Infertility and Sexual Dysfunction |
No
|
| NCT00406627 |
EGY
|
Ain Shams University; Cairo;
|
Research for Elimination of Lymphatic Filariasis (ICIDR) |
Observational |
|
Lymphatic Filariasis
|
2006-12-01 |
2011-12-01 |
Washington University School of Medicine |
No
|
| NCT03999372 |
Egypt
|
Al-Azhar University; Cairo;
|
Evaluation of Sperm Selection Technique Using Hyaluronic Acid Binding in Intra-cytoplasmic Sperm Injection (ICSI) |
Interventional |
Phase 4
|
Infertility, Male
|
2019-07-05 |
2020-01-10 |
ClinAmygate |
No
|
| NCT02878525 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Laparoscopic Internal Gastric Banding, New Simple and Costless Weight Loss Procedure |
Interventional |
Not Applicable
|
Morbid Obesity
|
2016-10-01 |
2017-12-01 |
Minia University |
No
|
| NCT03269838 |
EGY
|
Assiut University; Assiut;
|
Correlation of QT Dispersion With Myocardial Perfusion in Patients With ST Elevation Myocardial Infarction Treated by Primary Per Cutaneous Coronary Intervention |
Observational |
|
ST Elevation Myocardial Infarction
|
2018-07-01 |
2019-09-01 |
Assiut University |
No
|
| NCT04203368 |
EGY
|
Ain Shams University; Cairo;
|
Adenosine Versus Verapamil for Management of Supraventricular Tachycardia Post- Coronary Artery Bypass Grafting |
Interventional |
Not Applicable
|
Supraventricular Tachycardia
|
2020-02-01 |
2020-08-10 |
Ain Shams University |
No
|
| NCT01882335 |
|
|
Saving Brain in Uganda and Burkina Faso |
Interventional |
Not Applicable
|
Malnutrition,Neurologic Deficits,Infections, Hospital,Poor Performance Status,Mixed Behavior and Emotional Disorder
|
2013-04-01 |
2014-10-01 |
Makerere University |
No
|
| NCT02696824 |
|
|
Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa |
Interventional |
Not Applicable
|
Depressive Symptoms,Immunodeficiency Virus, Human
|
2016-07-19 |
2020-06-09 |
University of Miami |
No
|
| NCT03682848 |
|
|
Safety and Efficacy of Dolutegravir/Lamivudine (DTG/3TC) in Therapy-naive Human Immunodeficiency Virus-1 (HIV-1) Infected Adolescents |
Interventional |
Phase 3
|
HIV Infections
|
2019-04-09 |
2026-10-02 |
ViiV Healthcare |
No
|
| NCT01641367 |
ZAF, South Africa
|
Soweto ACTG CRS; Johannesburg;
JOSHA Research; Bloemfontein;
|
A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure |
Interventional |
Phase 4
|
HIV-1 Infection
|
2013-02-22 |
2018-12-31 |
AIDS Clinical Trials Group |
No
|
| NCT02527005 |
|
|
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients |
Interventional |
Phase 1
|
HIV,Malaria,Pregnant
|
2015-09-01 |
2016-08-01 |
University of Ibadan |
No
|
| NCT04744818 |
NGA, ETH
|
Department of Human Nutrition - University of Ibadan; Oyo;
Hawassa University Referral Hospital; Awassa;
|
Effects of Iron Supplementation on Pediatric Vaccine Response |
Interventional |
Not Applicable
|
Vaccination,Pediatric ALL,Iron-deficiency,Iron Deficiency Anemia
|
2021-02-07 |
2023-03-01 |
Nicole Stoffel |
No
|
| NCT03264391 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Evaluation of Macular Vascular Changes in Behcet's Disease Using Optical Coherence Tomography Angiography |
Observational |
|
Behcet Syndrome,Retinal Vasculitis
|
2018-03-01 |
2020-08-30 |
Assiut University |
No
|
| NCT04499027 |
EGY
|
Fayoum University Hospital; Fayoum;
|
Prognostic Value of Lung Ultrasound in Predicting Intensive Care Unit Length of Stay in Adult Cardiac Surgery |
Observational |
|
Valvular Heart Disease,Coronary Artery Disease
|
2020-08-01 |
2022-07-01 |
Fayoum University Hospital |
No
|
| NCT03653364 |
ZAF
|
Peermed Clinical Trial Centre; Kempton Park;
|
Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants From Birth to < 1 Year With Influenza-Like Symptoms |
Interventional |
Phase 3
|
Influenza
|
2019-01-23 |
2022-08-02 |
Hoffmann-La Roche |
No
|
| NCT04864444 |
NER
|
Madarounfa Health District; Niger;
|
Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities |
Interventional |
Not Applicable
|
Malaria,Malaria,Falciparum
|
2021-05-15 |
2022-12-31 |
University of California, San Francisco |
No
|
| NCT03852680 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Current Treatment Modalities for Wide Necked Intracranial Aneurysms |
Interventional |
Not Applicable
|
Brain Aneurysm
|
2019-03-01 |
2021-03-30 |
Assiut University |
No
|
| NCT03448302 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Computed Tomography Perfusion Colorectal Cancer With Tumor Grade |
Observational |
|
Colo-rectal Cancer
|
2018-03-10 |
2019-07-10 |
Assiut University |
No
|
| NCT02256046 |
|
|
Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices |
Interventional |
Not Applicable
|
Ulcer,Cirrhosis,Hypertension, Portal,Esophageal and Gastric Varices
|
2014-08-01 |
2015-03-01 |
Tanta University |
No
|
| NCT00066703 |
ZAF
|
Netcare Unitas Hospital; Centurion;
Manor Medical Center; Sandton;
|
Triptorelin With Either Exemestane or Tamoxifen in Treating Premenopausal Women With Hormone-Responsive Breast Cancer |
Interventional |
Phase 3
|
Breast Cancer
|
2003-11-03 |
2025-12-01 |
International Breast Cancer Study Group |
No
|
| NCT04454541 |
|
|
Efficacy of Ultrasound-Guided Multifidus Cervicis Plan Block Vs Greater Occipital Nerve Block for Cervicogenic Headache |
Interventional |
Not Applicable
|
Cervicogenic Headache
|
19-05-01 |
19-12-01 |
Abha International Private Hospital |
No
|
| NCT00140309 |
ZAF
|
Nelson R. Mandela School of Medicine - University of KwaZulu Natal; Durban;
|
TBTC Study 27: Moxifloxacin vs Ethambutol for TB Treatment |
Interventional |
Phase 2
|
Tuberculosis, Pulmonary
|
2003-07-01 |
2005-12-01 |
Centers for Disease Control and Prevention |
No
|
| NCT03417089 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Suspension of Falciform Ligament During Mini Gastric Bypass |
Interventional |
Not Applicable
|
Upper GIT Surgery
|
2018-02-01 |
2018-07-20 |
Minia University |
No
|
| NCT02047734 |
|
|
Efficacy and Safety Study of Ozanimod in Relapsing Multiple Sclerosis (Radiance Study) |
Interventional |
Phase 3
|
Relapsing Multiple Sclerosis
|
2013-12-03 |
2017-04-13 |
Celgene |
No
|
| NCT04509232 |
EGY
|
Ain Shams University; Cairo;
|
Assessing Parental Acceptance to Silver Diamine Fluoride Staining Before and After Masking the Colour With Glass Ionomer |
Interventional |
Not Applicable
|
Caries Arrested
|
2019-10-12 |
2021-12-30 |
Dina Bassam Mohamed Ahmed |
No
|
| NCT00431808 |
|
|
Safety and Immunogenicity of Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) |
Interventional |
Phase 1
|
Malaria
|
2007-05-01 |
2008-06-01 |
African Malaria Network Trust |
No
|
| NCT04646239 |
KEN
|
School of Medicine - Moi University; Eldoret;
|
Biomarkers of Trained Immunity Following MMR Vaccination |
Observational |
|
Covid19
|
2020-12-17 |
2021-06-01 |
Washington University School of Medicine |
Yes
|
| NCT01867125 |
ZAF
|
Gatesville Medical Centre; Cape Town;
|
A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication |
Interventional |
Phase 3
|
Asthma
|
2013-07-31 |
2017-01-02 |
Hoffmann-La Roche |
No
|
| NCT04660110 |
|
|
Household-level Impact of IPT of Malaria in Schoolchildren |
Interventional |
Phase 3
|
Malaria
|
2021-01-28 |
2021-06-30 |
Makerere University |
No
|
| NCT01032642 |
|
|
A Thin Catheter For Hystrosalpingography |
Interventional |
Not Applicable
|
Infertility
|
2008-09-01 |
2009-12-01 |
Kasr El Aini Hospital |
No
|
| NCT03343990 |
EGY
|
Assiut University; Assiut;
|
Comparison Between Interlocking Multi-twisted Wires and Eight Figure of Sternum Closure |
Observational |
|
Sternotomy Closure,Open Heart Surgery
|
2019-02-01 |
2020-12-30 |
Assiut University |
No
|
| NCT01345240 |
|
|
Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) |
Interventional |
Phase 3
|
Malaria,Malaria Vaccines
|
2011-11-17 |
2017-02-09 |
GlaxoSmithKline |
No
|
| NCT01323972 |
|
|
Consistency of Immunogenicity and Non Inferiority of GSK Biologicals' Candidate Malaria Vaccine Lots in Children |
Interventional |
Phase 3
|
Malaria
|
2011-05-16 |
2012-05-04 |
GlaxoSmithKline |
No
|
| NCT04556188 |
MAR, ETH, DZA, TUN
|
Ibn Rochd University Hospital; Casablanca;
College of Health Sciences - Black Lion Hospital; Addis Ababa;
Centre Hospitalo-universitaire Bologhine Hospital; Algiers;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
|
The Clinical Influence of Developing a Sustainable Cardiac Surgery Service to Reduce the Burden of Rheumatic Heart Disease in Sub-Saharan Africa |
Observational |
|
Rheumatic Heart Disease,Anticoagulant Adverse Reaction
|
2016-03-01 |
2021-12-31 |
Levanger Hospital |
No
|
| NCT03154398 |
EGY
|
Assiut University; Assiut;
|
Thyroid Dysfunction in Patients With Type 2 Diabetes With Early Diabetic Nephropathy. |
Observational |
|
Evaluation Thyroid Functions in Diabetic Patient
|
2017-06-01 |
2018-06-01 |
Assiut University |
No
|
| NCT04114032 |
|
|
BNP Evaluation Before Surgery Study: an Observational Study of Natriuretic Peptide Levels Prior to Surgery. |
Observational |
|
Surgery, Cardiovascular
|
2019-10-14 |
2020-04-29 |
University of Cape Town |
No
|
| NCT03800407 |
GHA
|
Kumasi Centre for Collaborative Research in Tropical Medicine - Kwame Nkrumah University of Science and Technology; Kumasi; (KCCR)
|
Contributing Factors for Poor HIV Treatment Response in Children With TB/HIV Coinfection |
Observational |
|
Coinfection,Tuberculosis,Human Immunodeficiency Virus
|
2019-01-28 |
2023-08-31 |
University of Florida |
No
|
| NCT02654184 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Right Lateral Positioning and Its Effect on Induction of General Anesthesia for Children |
Interventional |
Phase 2
|
Anesthesia
|
2016-01-01 |
2016-07-01 |
Assiut University |
No
|
| NCT03935464 |
KEN
|
Partners in Health and Research Development; Thika; (PHRD)
|
Point-of-care Urine Monitoring of Adherence (PUMA): Testing a Real-Time Urine Assay of Tenofovir in PrEP |
Interventional |
Not Applicable
|
Risk Reduction
|
2021-03-01 |
2021-09-01 |
University of California, San Francisco |
No
|
| NCT03498469 |
|
|
Reintegration of Children Into Family-based Care in Uganda |
Interventional |
Not Applicable
|
Parenting
|
2017-12-07 |
2019-10-01 |
Westat |
No
|
| NCT01705990 |
RWA
|
Project San Francisco; Kigali;
|
Safety and Immunogenicity Study of SeV-G(NP) HIV Vaccine Administered Intranasally and Ad35-GRIN HIV Vaccine Given Intramuscularly in Prime-Boost Regimens in HIV-Uninfected Volunteers |
Interventional |
Phase 1
|
HIV Infections
|
2013-03-01 |
|
International AIDS Vaccine Initiative |
No
|
| NCT04405648 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Computer Vision Syndrome Prevalence Among University Students |
Observational |
|
Computer Vision Syndrome
|
2020-05-28 |
2020-08-01 |
Sohag University |
No
|
| NCT00153777 |
|
|
Cellulose Sulfate and HIV Transmission Among Women |
Interventional |
Phase 3
|
HIV Infection
|
2005-07-01 |
2007-03-01 |
CONRAD |
No
|
| NCT00070447 |
ZAF
|
Pretoria Academic Hospital; Pretoria;
|
Rituximab, Prednisone, Cyclophosphamide, Doxorubicin, Vincristine, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Previously Untreated Mantle Cell Lymphoma |
Interventional |
Phase 2
|
Lymphoma
|
2003-11-01 |
2006-06-01 |
National Cancer Institute (NCI) |
No
|
| NCT02946294 |
|
|
Modified Pectoral Nerves Block Versus Serratus Plane Block in Major Breast Cancer Surgery |
Interventional |
Phase 2
|
Postoperative Pain
|
2016-10-01 |
2017-12-11 |
Cairo University |
No
|
| NCT01836003 |
|
|
An Intervention to Improve Antenatal Access to CD4 Testing and HAART in Botswana |
Interventional |
Not Applicable
|
Pregnancy,HIV Infection
|
2011-07-01 |
2012-10-01 |
Harvard School of Public Health |
No
|
| NCT02922140 |
EGY
|
Ain Shams University; Cairo;
|
The Impact of Pharmaceutical Care Practice on Patients in Cardiac Rehabilitation Unit |
Interventional |
Not Applicable
|
Acute Coronary Syndrome
|
2015-09-01 |
2017-08-01 |
Ain Shams University |
No
|
| NCT00216385 |
|
|
A Controlled Trial of a 4-Month Quinolone-Containing Regimen for the Treatment of Pulmonary Tuberculosis |
Interventional |
Phase 3
|
Tuberculosis
|
2005-01-01 |
2008-12-01 |
Institut de Recherche pour le Developpement |
No
|
| NCT02393495 |
|
|
Ultrasound Guided Intra-uterine Device Insertion |
Interventional |
Not Applicable
|
Contraception
|
2015-02-01 |
2015-08-01 |
Woman's Health University Hospital, Egypt |
No
|
| NCT00802802 |
|
|
Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children |
Interventional |
Phase 1
|
Tuberculosis,HIV Infections
|
2009-10-01 |
2016-03-01 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT04699058 |
COD
|
Institut National de Recherche Biomédicale; Kinshasa; (INRB)
|
COVID-19 Sero-prevalence Health Care Workers Kinshasa |
Observational |
|
Seroprevalence,SARS-CoV Infection
|
2020-07-17 |
2021-12-31 |
Institute of Tropical Medicine, Belgium |
Yes
|
| NCT00122382 |
|
Limaro Research; Bloemfontein;
|
Remission and Joint Damage Progression in Early Rheumatoid Arthritis |
Interventional |
Phase 3
|
Rheumatoid Arthritis
|
2005-07-01 |
2009-02-01 |
Bristol-Myers Squibb |
No
|
| NCT02676895 |
|
|
A Study of the Safety and Immune Response of 2 Doses of a New Shigella Vaccine in Kenyan Adults |
Interventional |
Phase 2
|
Shigella Sonnei Infection
|
2016-08-08 |
2017-03-10 |
GlaxoSmithKline |
No
|
| NCT00739206 |
ZAF
|
Sanofi-Aventis Administrative Office; Midrand;
|
Study of SAR97276A in the Treatment of Uncomplicated and Severe Malaria in Adults and Children. |
Interventional |
Phase 2
|
Malaria
|
2008-08-01 |
2009-06-01 |
Sanofi |
No
|
| NCT04148599 |
|
|
Effect of IV Infusion of Lidocaine Compared to IV Infusion of Dexmedetomidine on Proinflammatory Cytokines |
Interventional |
Phase 3
|
Inflammatory Response
|
18-01-02 |
20-01-01 |
National Cancer Institute, Egypt |
No
|
| NCT00470600 |
ZAF
|
Netcare Krugersdorp Hospital; Krugersdorp;
|
Efficacy and Safety Study of Caldolor (IV Ibuprofen) in Hospitalized Adult Orthopedic Patients |
Interventional |
Phase 3
|
Pain
|
2007-05-01 |
2008-09-01 |
Cumberland Pharmaceuticals |
No
|
| NCT03167463 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Stentless Endoscopic Transnasal Transseptal Choanoplasty |
Interventional |
Not Applicable
|
Otolaryngological Disease
|
2017-05-19 |
2019-05-01 |
Assiut University |
No
|
| NCT04041739 |
EGY
|
Assiut University; Assiut;
|
Fungal Infection in Patients With Diabetic Foot Osteomyelitis |
Observational |
|
Diabetic Foot Osteomyelitis
|
2020-01-01 |
2022-03-31 |
Assiut University |
No
|
| NCT03265977 |
TZA
|
National Institute for Medical Research; Tanga;
|
A Phase II Study of H56:IC31 in Healthy Adolescents |
Interventional |
Phase 2
|
Tuberculosis Infection
|
2018-06-01 |
2021-06-30 |
Aeras |
No
|
| NCT03276962 |
|
|
Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age |
Interventional |
Phase 2
|
Malaria
|
2017-09-28 |
2022-12-15 |
GlaxoSmithKline |
No
|
| NCT02918812 |
NGA
|
Aminu Kano Teaching Hospital; Kano; (AKTH)
|
Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief in HSG in a Tertiary Hospital in Kano |
Interventional |
Phase 4
|
Female Infertility of Tubal Origin
|
2016-09-01 |
2017-03-01 |
Bayero University Kano, Nigeria |
No
|
| NCT00678301 |
|
|
Primary Vaccination Course in Children Receiving the Pneumococcal Vaccine GSK 1024850A, Zilbrix™ Hib and Polio Sabin™ |
Interventional |
Phase 3
|
Infections, Streptococcal
|
2008-06-18 |
2009-12-10 |
GlaxoSmithKline |
No
|
| PACTR202007700757139 |
ZAF
|
Family Centre for Research with Ubuntu - Stellenbosh University; Cape Town; (FAMCRU)
|
TOGETHER 3 Trial. COVID-19 |
RCT |
|
Infections and Infestations
|
70-01-01 |
70-01-01 |
Cytel Inc |
Yes
|
| NCT00944281 |
BFA
|
Institut de Rechererch en Science de la Sante; Boulkiemdé;
|
Optimal Amount of Zinc to Include in a Lipid-based Nutrient Supplement (LNS) |
Interventional |
Not Applicable
|
Malnutrition
|
2010-05-01 |
2014-12-01 |
University of California, Davis |
No
|
| NCT02943902 |
|
|
Reduced PCV Dosing Schedules in South African Infants |
Interventional |
Phase 3
|
Pneumonia,Meningitis
|
2017-01-09 |
2019-02-26 |
University of Witwatersrand, South Africa |
No
|
| NCT02557256 |
EGY
|
Assiut University; Assiut;
|
Malignant Pediatric Pelvic Tumors: A Retrospective Study |
Observational |
|
Pelvic Neoplasms,Abdominal Neoplasms
|
2016-01-01 |
2020-12-01 |
Assiut University |
No
|
| NCT04641858 |
GNB
|
Bandim Health Project; Bissau; (BHP)
|
BCG to Reduce Absenteeism Among Health Care Workers During the COVID-19 Pandemic |
Interventional |
Phase 4
|
Covid19,Morbidity,Absenteeism
|
2020-12-03 |
2022-03-01 |
University of Southern Denmark |
Yes
|
| NCT01927484 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Hand OA AND Methotrexate Use |
Interventional |
Not Applicable
|
Reduction in Pain,Improvement in Function,Reduction of Inflammation
|
2020-03-07 |
2020-03-11 |
University of Alexandria |
No
|
| NCT00943306 |
|
|
Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia |
Interventional |
Phase 3
|
Familial Hypercholesterolemia
|
2009-10-29 |
2014-12-01 |
Aegerion Pharmaceuticals, Inc. |
No
|
| NCT03238846 |
|
|
Operations Research of the 'Real World' Effectiveness of Multi-Month Dispensing of ART for Stable Patients in CARGs in Zimbabwe |
Interventional |
Not Applicable
|
HIV/AIDS
|
2017-07-28 |
2019-09-30 |
Kheth'Impilo |
No
|
| NCT03880396 |
EGY
|
Assiut University; Assiut;
|
Concurrent Hypofractionated Rth With Weekly Cisplatin in Locally Advanced SCCHN |
Interventional |
Phase 2,Phase 3
|
Squamous Cell Carcinoma of the Head and Neck
|
2019-03-10 |
2021-12-10 |
Assiut University |
No
|
| NCT02678195 |
MWI
|
Kamuzu Central Hospital; Lilongwe;
|
3 Days Versus 5 Days Amoxicillin for Chest-indrawing Childhood Pneumonia in Malawi |
Interventional |
Phase 4
|
Pneumonia
|
2016-03-01 |
2019-12-01 |
Save the Children |
No
|
| NCT00144417 |
ZAF
|
Nelson R. Mandela School of Medicine - University of KwaZulu Natal; Durban;
|
TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment |
Interventional |
Phase 2
|
Tuberculosis
|
2006-02-01 |
2007-12-01 |
Centers for Disease Control and Prevention |
No
|
| NCT01434511 |
|
|
Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A |
Interventional |
Phase 3
|
Hemophilia A
|
2011-10-03 |
2013-07-29 |
Baxalta now part of Shire |
No
|
| NCT04805112 |
KEN
|
Impact Research and Development Organization; Kisumu; (IRDO)
|
Acceptability, Feasibility and Impact of Oral HIV Self-testing for Partner Testing Among Kenyan Adolescent Girls Aged 15-19 Years: A Randomized Controlled Trial |
Interventional |
Not Applicable
|
Human Immunodeficiency Virus
|
2021-03-15 |
2021-12-31 |
University of Pennsylvania |
No
|
| PACTR202008705259380 |
NGA
|
Life Fertility Centre - Life International Hospital; Anambra;
|
RANDOMIZED CONTROL TRIAL ON THE EFFECTIVENESS OF ECHO TIP VERSUS NON-ECHO TIP EMBRYO TRANFER CATHETER FOR IMPROVING PREGNANCY RATE IN IN-VITRO FERTILIZATION CYCLES IN ANAMBRA STATE, NIGERIA |
RCT |
|
Obstetrics and Gynecology
|
70-01-01 |
70-01-01 |
Joseph Ikechebelu |
No
|
| NCT00623337 |
Ghana
|
Kintampo Health Research Centre; Kintampo; (KHRC)
|
Ghana Newborn Home Visits Neonatal Mortality Trial |
Interventional |
Phase 3
|
Neonatal Mortality
|
2009-01-01 |
2010-04-01 |
London School of Hygiene and Tropical Medicine |
No
|
| NCT03565575 |
|
|
Manicaland PrEP Uptake Through Interactive Counselling Trial |
Interventional |
Not Applicable
|
Improving Perceptions of HIV Risk,Improving Uptake of Pre-exposure Prophylaxis for HIV
|
2018-07-07 |
2021-01-01 |
Simon Gregson |
No
|
| NCT03885895 |
|
|
Treatment of Freckles by Intradermal Tranexamic Acid Versus Q Switched KTP Laser. |
Interventional |
Phase 1
|
Therapeutic Efficacy
|
2019-01-15 |
2019-12-01 |
Kasr El Aini Hospital |
No
|
| NCT01571804 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
Pregabalin Reduce the Sevoflurane Requirement |
Interventional |
Phase 2
|
Sevoflurane Anesthesia,Elective Laparoscopic Cholecystectomy
|
2011-12-01 |
2012-03-01 |
Mansoura University |
No
|
| NCT04472715 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Hair Transplantation in Cicatricial Alopecia |
Interventional |
Not Applicable
|
Cicatricial Alopecia,Hair Transplantation
|
2020-01-05 |
2021-01-01 |
Alexandria University |
No
|
| NCT04199156 |
|
|
Evaluation of Non-invasive Blood Pressure Measured at the Ankle During Cesarean Delivery Compared to the Arm |
Observational |
|
Cesarean Delivery,Spinal Anesthesia,Non-invasive Blood Pressure
|
2019-12-01 |
2020-02-01 |
Kasr El Aini Hospital |
No
|
| NCT01699633 |
GHA
|
Komfo Anokye Teaching Hospital; Kumasi;
|
Rifampin and Nevirapine Interactions in Young Children |
Observational |
|
HIV,Tuberculosis
|
2012-10-01 |
2017-05-01 |
The Miriam Hospital |
No
|
| NCT00448058 |
|
|
A Study Of New Medicine (GSK 372475) For The Treatment Of Depression |
Interventional |
Phase 2
|
Depressive Disorder
|
2007-04-01 |
2008-12-01 |
GlaxoSmithKline |
No
|
| NCT03212833 |
EGY
|
Assiut University; Assiut;
|
Impact of Insulin Resistance on Therapeutic Response for Oral Treatment of Chronic Hepatitis C Virus Infection |
Observational |
|
Hepatitis C
|
2017-05-01 |
2018-12-01 |
Assiut University |
No
|
| NCT03831906 |
NGA
|
Lagos University Teaching Hospital; Idi Araba;
|
TB-Speed Pneumonia |
Interventional |
Not Applicable
|
Tuberculosis,Severe Pneumonia
|
2019-03-20 |
2020-12-23 |
Institut National de la Santé Et de la Recherche Médicale, France |
No
|
| NCT00289185 |
|
|
Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants |
Interventional |
Phase 2
|
Malaria
|
2006-09-27 |
2009-01-15 |
GlaxoSmithKline |
No
|
| NCT01245309 |
|
|
Endometrial Scratching Prior to Controlled Ovarian Stimulation (COH) in Women Undergoing In-vitro Fertilization With Previous IVF Failure |
Interventional |
Early Phase 1
|
Infertility
|
2010-12-01 |
2013-12-01 |
Mansoura University |
No
|
| NCT04561063 |
ZAF
|
Charlotte Maxeke Johannesburg Academic Hospital; Johannesburg;
Sanofi-Aventis Administrative Office; Midrand;
|
COVID-19 Prophylaxis South Africa (COVER HCW) |
Interventional |
Phase 2
|
Covid19,SARS-CoV Infection
|
2020-12-08 |
2021-07-01 |
University of Witwatersrand, South Africa |
Yes
|
| NCT04457050 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Effect of Hepatitis C Clearance on Insulin Resistance |
Interventional |
Phase 4
|
Hepatitis C,Insulin Resistance
|
17-10-30 |
19-12-30 |
Alexandria University |
No
|
| NCT00065325 |
ZAF
|
Groote Schuur Clinical Research Site; Cape Town;
|
The Evaluation of the Efficacy and Tolerability of FASLODEX (Fulvestrant) and AROMASIN (Exemestane) in Hormone Receptor Positive Postmenopausal Women With Advanced Breast Cancer |
Interventional |
Phase 3
|
Metastatic Breast Cancer,Locally Advanced Breast Cancer
|
2003-08-01 |
2014-09-01 |
AstraZeneca |
No
|
| NCT00341393 |
|
|
Validation of System for Monitoring the Effectiveness of Antiretroviral Therapy in HIV-Infected Patients in Africa |
Observational |
|
HIV
|
2006-02-16 |
2007-11-15 |
National Institute of Allergy and Infectious Diseases (NIAID) |
No
|
| NCT00005970 |
ZAF
|
Mamma Clinic; Cape Town;
|
Doxorubicin Hydrochloride, Cyclophosphamide, and Pacltaxel With or Without Trastuzumab in Treating Women With HER2-Positive Node-Positive or High-Risk Node-Negative Breast Cancer |
Interventional |
Phase 3
|
Breast Adenocarcinoma,HER2 Positive Breast Carcinoma,Stage IA Breast Cancer AJCC v7,Stage IB Breast Cancer AJCC v7,Stage IIIA Breast Cancer AJCC v7,Stage IIA Breast Cancer AJCC v6 and v7,Stage IIB Breast Cancer AJCC v6 and v7
|
2000-05-19 |
2010-01-27 |
National Cancer Institute (NCI) |
No
|
| NCT04897919 |
GNB
|
Bandim Health Project; Bissau; (BHP)
|
Effectiveness and Safety of Artemether + Lumefantrine and Dihydroartemisinin + Piperaquine for the Treatment of Uncomplicated Malaria in Guinea-Bissau |
Interventional |
Phase 4
|
Malaria,Effectiveness
|
2015-08-01 |
2018-12-01 |
Bandim Health Project |
No
|
| NCT02735590 |
ZAF
|
South African Tuberculosis Vaccine Initiative; Cape Town; (SATVI)
Centre for the Aids Programme of Research in South Africa; Durban; (CAPRISA)
|
The Correlate of Risk Targeted Intervention Study |
Interventional |
Phase 2,Phase 3
|
Tuberculosis
|
2016-09-20 |
2019-12-31 |
University of Cape Town |
No
|
| NCT03517137 |
|
|
Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study |
Interventional |
Phase 2
|
Advanced Hodgkin Lymphoma
|
2019-08-01 |
2023-09-01 |
European Organisation for Research and Treatment of Cancer - EORTC |
No
|
| NCT04694014 |
KEN
|
Department of Paediatrics - Alupe University College; Busia;
|
Emotional Intelligence Skills Health Leaders Need During Covid-19 |
Observational |
|
Covid-19,Leadership,Emotional Intelligence,Health Personnel Attitude
|
2020-10-15 |
2021-06-30 |
African Wood Inc |
Yes
|
| NCT03836833 |
Uganda
|
Joint Clinical Research Centre; Lubowa;
|
Lopinavir/r/ Lamivudine/ Abacavir as an Easy to Use Paediatric Formulation |
Interventional |
Phase 1,Phase 2
|
HIV
|
19-06-04 |
19-12-01 |
Drugs for Neglected Diseases |
No
|
| NCT04110197 |
EGY
|
Assiut University; Assiut;
|
Demographic Outcomes, and Health Care Resources in Newly Diagnosed Non Valvular AF Patients |
Observational |
|
Non Valvular AF ,AF
|
2019-11-01 |
2021-12-01 |
Assiut University |
No
|
| NCT02480153 |
ZAF
|
Clinresco Centres limited; Ekurhuleni; (PTY LTD)
Panaroma Medical Centre; Parow;
|
A Study Of PF-06410293 (Adalimumab-Pfizer) And Adalimumab (Humira®) In Combination With Methotrexate In Subjects With Active Rheumatoid Arthritis (REFLECTIONS B538-02). |
Interventional |
Phase 3
|
Rheumatoid Arthritis
|
2015-06-25 |
2017-12-06 |
Pfizer |
No
|
| NCT00259142 |
TZA
|
Nyamagana District Hospital; Mwanza;
|
Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies |
Interventional |
Not Applicable
|
Fever,Anaemia,Malaria
|
2005-11-01 |
2005-11-01 |
DBL -Institute for Health Research and Development |
No
|
| NCT03131193 |
NGA
|
Aminu Kano Teaching Hospital; Kano; (AKTH)
|
Primary Care Provider Supply and Patient Outcomes |
Interventional |
Not Applicable
|
Health Behavior,Health Services Accessibility,Health Care Quality, Access, and Evaluation
|
2017-03-20 |
2021-06-30 |
RAND |
No
|
| NCT03923725 |
COD, NER, GIN
|
Kinshasa School of Public Health - Universite de Kinshasa; Kinshasa; (KSPH)
Epicentre Research centers; Maradi;
Centre National De Formation Et De Recherche En Sante Rurale De Maferinyah; Maferinyah;
|
A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. |
Interventional |
Phase 3
|
Plasmodium Falciparum Malaria (Uncomplicated)
|
2020-09-01 |
2022-07-15 |
University of Oxford |
No
|
| NCT00123552 |
UGA
|
Mulago National Referral and Teaching Hospital complex; Kampala;
|
Longitudinal Antimalarial Combinations in Uganda |
Interventional |
Phase 3
|
Malaria
|
2004-11-01 |
2008-12-01 |
University of California, San Francisco |
No
|
| NCT04506736 |
EGY
|
Faculty of Medicine - Zagazig University; Zagazig;
|
Open Lung Approach Versus Conventional Protective Ventilation in Obese Patients Undergoing Open Abdominal Surgery |
Interventional |
Not Applicable
|
Obese Patients,Abdominal Surgery
|
2020-01-30 |
2021-03-01 |
Zagazig University |
No
|
| NCT01499277 |
ZAF
|
Groote Schuur Clinical Research Site; Cape Town;
|
Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections |
Interventional |
Phase 3
|
Complicated Skin and Soft Tissue Infection
|
2012-05-01 |
2015-01-01 |
Pfizer |
No
|
| NCT04379219 |
|
|
Surgery Alone Versus Methotrexate Before Surgery in Cesarean Scar Pregnancy |
Interventional |
Phase 4
|
Cesarean Scar Pregnancy
|
2019-12-01 |
2020-12-01 |
Mansoura University |
No
|
| NCT04053764 |
ZAF, NGA, GHA, MWI, ZWE, EGY
|
Manor Medical Center; Sandton;
Department of Paediatrics - University of Calabar; Calabar;
School of Public Health Research Centre - University of Health and Allied Sciences; Ho Volta; (SPH UHAS)
University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC)
St Mary's Clinical Research Site -The University of Zimbabwe College of Health Sciences Clinical Trials Research Centre; Harare; (UZCHS-CTRC)
Investigator Clinic; Giza;
University Of Health And Allied Sciences; Ho Volta Region;
Ladywell Medical Centre West; Durban;
|
Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease |
Interventional |
Phase 2
|
Sickle Cell Disease (SCD)
|
2019-12-10 |
2024-01-20 |
Novartis Pharmaceuticals |
No
|
| NCT01747369 |
ZAF
|
Poli Clinic; Port Elizabeth;
|
Surveillance of Hospitalised Pneumonia and Bacterial Meningitis in Tône District, Togo, 2010-2013 |
Observational |
|
Pneumonia, Viral,Pneumonia, Bacterial,Meningitis, Bacterial
|
2010-04-01 |
2017-06-01 |
Agence de Médecine Préventive, France |
No
|
| NCT00620438 |
|
|
Drug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patients |
Interventional |
Phase 4
|
Tuberculosis,HIV Infections
|
2008-02-01 |
2011-07-01 |
Makerere University |
No
|
| NCT03185520 |
ZAF
|
Tiervlei Trial Centre; Bellville; (TTC)
|
Young ESUS Patient Registry |
Observational |
|
Embolic Stroke of Undetermined Source
|
2017-02-15 |
2020-12-17 |
Population Health Research Institute |
No
|
| NCT02763566 |
ZAF
|
Eastleigh Breast Care Centre; Pretoria;
|
A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer |
Interventional |
Phase 3
|
Breast Cancer
|
2016-12-05 |
2021-12-31 |
Eli Lilly and Company |
No
|
| NCT03793660 |
TUN
|
Rheumatology Department - Habib Thameur Hospital; Tunis;
|
Biologic National Registry |
Observational |
|
Spondylitis,Arthritis, Rheumatoid
|
2018-05-23 |
2022-12-31 |
Dacima Consulting |
No
|
| NCT04034771 |
|
|
The Effect of Melatonin Administration on Sedation Level as Adjuvant to Propofol |
Interventional |
Phase 3
|
TBI (Traumatic Brain Injury)
|
2018-01-01 |
2018-04-05 |
Cairo University |
No
|
| NCT00722137 |
ZAF, BDI, TUN
|
RK Khan Hospital; Chatsworth;
Institut National d'Oncologie; Bujumbura;
Salah Azaiez Institute; Tunis;
Oncology department - University of Witwatersrand; Johannesburg;
|
Study of the Combination of Rituximab, Cyclophosphamide, Doxorubicin, VELCADE, and Prednisone or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Mantle Cell Lymphoma |
Interventional |
Phase 3
|
Mantle Cell Lymphoma
|
2008-05-01 |
2017-06-17 |
Millennium Pharmaceuticals, Inc. |
No
|
| NCT02219490 |
|
|
A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection |
Interventional |
Phase 3
|
Chronic Hepatitis C Virus (HCV) Infection Genotype 1
|
2014-10-30 |
2021-05-12 |
AbbVie |
No
|
| PACTR202008534546951 |
EGY
|
Poison Control Center - Tanta University; Tanta;
|
Insulin-Euglycemia Therapy in Acute Aluminum Phosphide Poisoning: A Randomized Controlled Clinical Trial |
RCT |
|
Injury, Occupational Diseases, Poisoning
|
20-04-08 |
70-01-01 |
Tanta University |
No
|
| NCT00334282 |
|
|
Safety and Efficacy of GW786034 (Pazopanib) In Metastatic Renal Cell Carcinoma |
Interventional |
Phase 3
|
Carcinoma, Renal Cell
|
2006-04-01 |
2014-12-01 |
GlaxoSmithKline |
No
|
| NCT03459976 |
EGY
|
Ain Shams University; Cairo;
|
HE4 is a Beneficial Biomarker in Endometrial Cancer |
Observational |
|
Endometrial Cancer
|
2017-12-01 |
2019-04-01 |
Ain Shams University |
No
|
| NCT04470323 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Functional Exhaustion of T Cells in COVID19 Patients |
Observational |
|
T Cell Deficiency
|
2020-07-22 |
2020-11-01 |
Assiut University |
Yes
|
| NCT04661878 |
ZAF, MWI
|
University of Cape Town; Cape Town;
University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC)
|
Piloting a Smartphone App to Improve Treatment Adherence Among South African Adolescents Living With HIV |
Interventional |
Not Applicable
|
HIV Infections,Adolescent Behavior
|
2021-10-01 |
2023-06-01 |
Duke University |
No
|
| NCT02685085 |
|
|
Combined Method for Induction of Labor |
Interventional |
Phase 2
|
Induced Labor
|
2016-02-01 |
2016-08-01 |
Woman's Health University Hospital, Egypt |
No
|
| NCT02597816 |
EGY
|
Assiut University; Assiut;
|
Role of Three Dimensional Ultrasound in the Diagnosis of Septate Uterus |
Interventional |
Phase 2
|
Infertility
|
2013-10-01 |
2014-07-01 |
Assiut University |
No
|
| NCT04284007 |
|
|
Intravenous Versus Perineural Effect Dexamethasone in Interscalene Nerve Block With Levobupivacaine |
Interventional |
Not Applicable
|
Shoulder Pain
|
2019-12-02 |
2020-12-01 |
Mansoura University |
No
|
| NCT02398123 |
|
|
Transversus Abdominis Plane Versus Caudal Block for Pediatrics |
Interventional |
Phase 1
|
Lower Abdominal Surgery
|
2015-03-01 |
2015-07-01 |
Mansoura University |
No
|
| NCT03552185 |
|
|
Depicting Neurogenic Dysphagia in Multiple Sclerosis Patients; Clinical and Endoscopic Studies |
Observational |
|
Multiple Sclerosis
|
2018-01-01 |
2018-06-15 |
Kasr El Aini Hospital |
No
|
| NCT01470612 |
ZAF
|
Medi-clinic Panorama; Parow;
Mamma Clinic; Cape Town;
|
Long-Term Study Of CP-690,550 In Subjects With Ulcerative Colitis |
Interventional |
Phase 3
|
Ulcerative Colitis
|
2012-10-01 |
2020-08-06 |
Pfizer |
No
|
| NCT00872469 |
|
|
World Maternal Antifibrinolytic Trial |
Interventional |
Phase 3
|
Postpartum Haemorrhage
|
2009-05-01 |
2017-04-01 |
London School of Hygiene and Tropical Medicine |
No
|
| NCT02373020 |
|
|
Enteropathogenic Escherichia Coli (EPEC): Does it Have a Role in Colorectal Tumourigenesis? |
Observational |
|
Colorectal Carcinoma,Enteropathogenic Escherichia Coli .
|
2011-01-01 |
2013-03-01 |
Mansoura University |
No
|
| NCT01914601 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
King Vision and Cervical Spines Movement |
Interventional |
Phase 2
|
Need Tracheal Intubation
|
2014-01-01 |
2016-01-01 |
Dammam University |
No
|
| NCT03013673 |
ETH
|
Abdurafi Health Center; Abdurafi;
|
Predicting Visceral Leishmaniasis in HIV Infected Patients |
Observational |
|
Leishmaniasis, Visceral
|
2017-10-11 |
2021-12-01 |
Institute of Tropical Medicine, Belgium |
No
|
| NCT02737800 |
|
|
Effect of Prolonged GnRh Agonists on Results of Intracytoplasmic Sperm Injection (ICSI ) in Endometrioma Patients |
Interventional |
Not Applicable
|
Endometrioma
|
2016-04-01 |
2017-08-01 |
Kasr El Aini Hospital |
No
|
| NCT01098266 |
|
|
NGR015: Study in Second Line for Patient With Advanced Malignant Pleural Mesothelioma Pretreated With Pemetrexed |
Interventional |
Phase 3
|
Malignant Pleural Mesothelioma
|
2010-04-12 |
2017-12-01 |
MolMed S.p.A. |
No
|
| NCT00101998 |
|
|
Study Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication |
Interventional |
Phase 2
|
Constipation,Bowel Dysfunction
|
2003-10-01 |
2006-05-01 |
Cubist Pharmaceuticals LLC |
No
|
| NCT03886246 |
ZAF, EGY, BFA, NAM, CMR, NGA, KEN, TUN
|
Department of Dermatology - Groote Schuur Hospital; Cape Town;
Louis Pasteur Hospital; Pretoria;
Cardiology Department - Suez Canal University; Ismailia;
University Of Dakar; Dakar;
Clinical research Unit of Nanoro - Saint Camille Medical Center of Nanoro; Ouagadougou; (CRUD - CMA)
Windhoek Central Hospital; Wanaheda Zone;
Douala General Hospital; Douala;
Health Services Department - University of Benin; Benin;
Bondo Clinic - Bondo District Hospital; Bondo;
Albert Alberts Stem Cell Transplant Centre; Pretoria;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Siaya District Hospital; Siaya;
Phelang Private Hospital Research Centre; Mamelodi;
The Aga Khan University Hospital; Nairobi;
NESTRA KLINIkAL; Ibadan;
School of Medicine - Moi University; Eldoret;
|
A 5-year Study to Test BI 655130 in Patients With Generalized Pustular Psoriasis Who Took Part in Previous Studies With BI 655130 |
Interventional |
Phase 2
|
Generalized Pustular Psoriasis
|
2019-05-27 |
2028-01-20 |
Boehringer Ingelheim |
No
|
| NCT00144339 |
ZAF
|
Poli Clinic; Port Elizabeth;
|
Evaluation of the Long- Term Effects of Spiriva on Lung Function in COPD Patients |
Interventional |
Phase 3
|
Pulmonary Disease, Chronic Obstructive
|
2002-12-01 |
|
Boehringer Ingelheim |
No
|
| NCT01323660 |
|
|
An Exercise Endurance Study to Evaluate the Effects of Treatment of Chronic Obstructive Pulmonary Disease (COPD) Patients With a Dual Bronchodilator: GSK573719/GW642444.Study B |
Interventional |
Phase 3
|
Pulmonary Disease, Chronic Obstructive
|
2011-03-16 |
2012-07-16 |
GlaxoSmithKline |
No
|
| NCT04382495 |
EGY
|
EgyBrit Medical Centre; Cairo;
|
The Impact of COVID-19 Pandemic on Cancer Care |
Observational |
|
Cancer
|
2020-06-15 |
2020-08-31 |
El Zaitoun Specialized Hospital |
Yes
|
| NCT01006863 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
Preoperative Ephedrine Attenuates the Hemodynamic Responses of Propofol During Valve Surgery: A Dose Dependent Study |
Interventional |
Phase 2
|
Hypotension,Valve Surgery
|
2004-03-01 |
2010-03-01 |
King Faisal University |
No
|
| NCT00273975 |
|
|
Trial to Evaluate Steady State Pharmacokinetic Parameters, Efficacy and Safety of Nevirapine in Antiretroviral Drug naïve Pediatric Patients |
Interventional |
Phase 2
|
HIV Infections
|
2002-01-01 |
2004-12-01 |
Boehringer Ingelheim |
No
|
| NCT02635425 |
EGY
|
Ain Shams University; Cairo;
|
Aspiration of Limited Number of Follicles to Prevent Severe Ovarian Hyperstimulation Syndrome |
Interventional |
Not Applicable
|
Infertility
|
2015-11-01 |
2016-03-01 |
Ahmad Hussieny Salama |
No
|
| NCT02678221 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Sildenafil Citrate for the Management of Asymmetrical Intrauterine Growth Restriction |
Interventional |
Phase 2
|
Intrauterine Growth Restriction
|
2016-02-01 |
2017-04-01 |
Assiut University |
No
|
| NCT03408392 |
|
|
Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions |
Interventional |
Phase 1
|
Infections, Bacterial
|
2018-02-06 |
2018-03-13 |
GlaxoSmithKline |
No
|
| NCT04635332 |
ZAF
|
Medigate Medical Centre; Umhlanga;
|
Food Literacy and Physical Activity Intervention to Optimize Metabolic Health Among Women in Urban Uganda |
Interventional |
Not Applicable
|
Abdominal Obesity
|
2020-11-21 |
2021-05-08 |
KU Leuven |
No
|
| NCT03605186 |
|
|
Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy. |
Interventional |
Not Applicable
|
Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
|
2019-02-01 |
2020-03-01 |
Cairo University |
No
|
| NCT04240431 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Level of Lacrimal Passage Obstruction |
Observational |
|
Lacrimal Apparatus Diseases
|
2017-01-01 |
2019-12-21 |
Minia University |
No
|
| NCT04484558 |
EGY
|
Assiut University; Assiut;
|
Anxiety and Depression Disorder in Patient Treated With rTPA for Mangment of Acute Ischemic Stroke |
Observational |
|
Depression,Acute Stroke,Anxiety Disorders
|
2020-01-01 |
2021-12-01 |
Assiut University |
No
|
| NCT04283773 |
EGY
|
Assiut University; Assiut;
|
Immunohistochemical Evaluation of Protein P16 Expression in Ovarian Germ Cell Tumors. |
Observational |
|
Ovarian Neoplasms
|
2019-12-24 |
2021-10-31 |
Assiut University |
No
|
| NCT03329092 |
ZAF
|
Tiervlei Trial Centre; Bellville; (TTC)
|
A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria. |
Interventional |
Phase 3
|
Hosptial Acquired Pneumonia,Ventilator Associated Pneumonia,Complicated Intra-abdominal Infection
|
2018-04-05 |
2022-12-14 |
Pfizer |
No
|
| NCT04343001 |
|
|
Coronavirus Response - Active Support for Hospitalised Covid-19 Patients |
Interventional |
Phase 3
|
Covid-19
|
2020-10-01 |
2021-08-01 |
London School of Hygiene and Tropical Medicine |
Yes
|
| NCT04375020 |
ZAF
|
Sefako Makgatho Health Sciences University; Ga-Rankuwa; (MEDUNSA)
|
GABA and Beta-cell Regeneration |
Observational |
|
Diabetes Mellitus, Type 1
|
2019-11-01 |
2020-05-02 |
Ministry of Health and Population, Egypt |
No
|
| NCT04336059 |
ZAF
|
Tara Hospital; Cape Town;
|
Pericapsular Nerve Group Block in Hip Arthroplasty |
Interventional |
Not Applicable
|
Post Operative Pain After Hip Arthroplasty
|
2020-05-01 |
2020-12-01 |
Tanta University |
No
|
| NCT01352117 |
South Africa
|
JOSHA Research; Bloemfontein;
|
Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma |
Interventional |
Phase 3
|
HIV-1 Infection,Kaposi's Sarcoma
|
2011-11-18 |
2018-11-29 |
AIDS Clinical Trials Group |
No
|
| NCT03540667 |
|
|
Study of Hip and Knee Arthroplasty in South Africa |
Observational |
|
Arthritis Knee,Arthritis of Hip,Osteoarthritis, Hip,Osteoarthritis, Knee,Arthritis, Rheumatoid
|
2018-05-07 |
2019-01-30 |
University of Cape Town |
No
|
| NCT03634488 |
NGA
|
Aminu Kano Teaching Hospital; Kano; (AKTH)
|
Management of Severe Acute Malnutrition in SCD, in Northern Nigeria |
Interventional |
Phase 2
|
Sickle Cell Anemia,Severe Acute Malnutrition
|
2021-07-01 |
2022-12-01 |
Vanderbilt University Medical Center |
No
|
| NCT02237326 |
KEN
|
Family AIDS Care and Education Services; Kisumu; (FACES)
|
Visual Inspection With Acetic Acid Compared to Lugol's Iodine in HIV-infected Women |
Interventional |
Not Applicable
|
HIV,Cervical Cancer,Cervical Intraepithelial Neoplasia
|
2011-10-01 |
2012-10-01 |
University of California, San Francisco |
No
|
| NCT02524444 |
|
|
A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients |
Interventional |
Phase 1
|
Malaria in Pregnant HIV + Patients
|
2015-09-01 |
2016-08-01 |
ORIYOMI OMOTOYOSI AKINYOTU |
No
|
| NCT02188355 |
ZAF
|
Netcare Unitas Hospital; Centurion;
Tara Hospital; Cape Town;
Milpark Hospital; Johannesburg;
|
Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry |
Observational |
|
Coronary Artery Disease
|
2014-06-01 |
2020-06-01 |
Terumo Europe N.V. |
No
|
| NCT04709302 |
NGA, South Africa
|
Lagos University Teaching Hospital; Idi Araba;
Walter Sisulu University HIV Vaccine Research Unit CRS; Mthatha;
Department of Paediatrics and Child Health - University of Ilorin Teaching Hospital; Ilorin;
|
Effects of COVID-19 on Endothelium in HIV-Positive Patients in Sub-Saharan Africa |
Observational |
|
ART,Hiv,Covid19
|
2021-02-01 |
2022-12-01 |
Medical University of Graz |
Yes
|
| NCT01716299 |
ETH
|
Abdurafi Health Center; Abdurafi;
|
Comparison of HIV Testing Algorithms |
Observational |
|
HIV Infection
|
2010-12-01 |
2013-12-01 |
Medecins Sans Frontieres, Netherlands |
No
|
| NCT04191005 |
EGY
|
Assiut University; Assiut;
|
Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia: A Systematic Review and Meta-analysis |
Observational |
|
Androgenetic Alopecia
|
2020-01-07 |
2020-01-30 |
Jasim Mohammed Alshammari |
No
|
| NCT04614948 |
EGY, NGA, South Africa, ZMB, ZAF, SEN, Tanzania, GHA, MAR, UGA, ETH, Ghana, Kenya, Sierra Leone, BWA, NER, GAB, MWI, CIV, CMR, DZA, TZA, ZWE, TUN, CAF, LBR, MOZ, KEN, SDN
|
Clinical Research Center - Cairo University; Giza;
Princess Marina Hospital; Port Harcourt;
TASK Clinical Research Centre; Bellville;
Choma District Health Office; Choma;
Medipark Centre for Clinical Research; Centurion;
Clinique des Maladies Infectieuses Ibrahima-Diop-Mar; Dakar;
Tropical Diseases Research Center; Ndola; (TDRC)
Midrand Medical Centre; Johannesburg;
Synexus Stanza Clinical Research Centre; Mamelodi;
Engelbrecht Research Limited; Centurion; (PTY)
Paarl Research Centre; Paarl;
Tropical Pesticides Research Institute; Arusha;
Korle Bu Teaching Hospital; Accra;
Manor Medical Center; Sandton;
Cardiology Clinical Research; Alberton;
Africa Health Research Institute; Durban;
College of Medicine - University of Lagos; Lagos;
Boland Ethical Research Group; Western Cape;
Global Clinical Trials; Pretoria;
Scion Clinical Research; Pretoria;
Rahima Moosa Mother and Child Hospital; Johannesburg;
Niakhar Demographic Surveillance System; Dakar;(DS IDR)
Enhancing Care Foundation; Durban;
Center Hospitalier Universitaire Mohammed VI; Marrakesh; (CHU)
Family Clinical Research Unit - Tygerberg Hospital; Tygerberg; (FAM-CRU CRS)
TASK Foundation; Bellville;
Germ Cell Tumors Trials Centre; Port Elizabeth;
Baylor Uganda Clinical Research Sites; Kampala; (CRS)
Hawassa University Referral Hospital; Awassa;
Practice Prof. Y Elhawary - AlSalama Hospital; Cairo;
Langeberg Clinical Trials; Cape Town;
Life Fertility Centre - Life International Hospital; Anambra;
Center for Clinical Care and Clinical Research; Abuja; (CCCRN)
University of Cape Coast; Cape Coast;
Mount Kenya University Trust; Thika; (MKU)
Kuils river Hospital; Kuils River;
Be Part Yoluntu Centre; Paarl;
Drs Gudgeon and Boeddinghaus Associates; Cape Town;
TUBERCULOSIS RESEARCH; Freetown;
Netcare Christiaan Barnard Memorial Hospital; Cape Town;
Hôpital de Fann; Dakar;
George Clinical Study Site; George;
University of Botswana/McMAsters University; Gaborone;
Clinical Research Center - Air Force Specialized Hospital; Cairo;
Precise Clinical Solutions; Chatsworth;
Epicentre Research centers; Maradi;
Universite de Medecine et Science de la Sante; Libreville;
PAREXEL Port Elizabeth; Port Elizabeth;
Nigeria Global Health Trials Network; National Hospital Abuja; Abuja
University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC)
Cocody University Hospital Center; Abidjan;
The College; Cape Town;
Douala General Hospital; Douala;
Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH)
Centre Hospitalo-universitaire Bologhine Hospital; Algiers;
Central Primary Health Centre; Akahia;
Leishmania Research and Treatment Center - Arba Minch General Hospital; Arba Minch; (LRTC)
National Institute for Medical Research - Mbeya Medical Research Center; Mbeya; (MMRC NIMR)
Chelmsford Medical Centre; Durban;
Africa University Clinical Research Centre; Mutare; (AUCRC)
Hopital Militaire; Tunis;
Worthwhile Clinical Trials - Medinova Merc; Benoni;
Medical Research Council Uganda Virus Research Institute Research Unit on AIDS; Entebbe;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Cape Allergy and Asthma Clinic; Western Cape;
Medpark; Cape Town;
Institut Pasteur de Bangui; Bangui;
VX Pharma; Pretoria;
Medicross Medical Centre Parow; Cape Town;
The Liberia-U.S. clinical research partnership; Liberia; (PREVAIL)
Health and Wellness Clinic; Pretoria;
Ethiopian Public Health Association; Addis Ababa;
South Valley University; Qena;
Hiway Medical Center; Durban;
Instituto Nacional de Saúde; Maputo; (INS)
Clinical Research Center - Muelmed Hospital; Pretoria;
NESTRA KLINIkAL; Ibadan;
Jan S Marais Hospital; Bellville;
Emery Clinical Services; Alberton;
Excellentis Clinical Trial Consultants; George;
Hôpital national de Lamordé; Niamey;
Johese Clinical Research; Centurion;
Peermed Clinical Trial Centre; Kempton Park;
Mt Edgecombe Hospital; Phoenix;
School of Medicine - Moi University; Eldoret;
Moriana Clinical Research; Free State;
Netcare Moot General Hospital; Pretoria;
Beitbridge District Hospital; Beitbridge;
Omdurman Teaching Hospital; Khartoum;
Damien Foundation; Abuja;
Service de Rhumatologie-Hôpital La Rabta; Sfax;
University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF)
Marondera Provincial Hospital; Harare;
|
A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults |
Interventional |
Phase 3
|
Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19
|
2020-11-16 |
2023-05-31 |
Janssen Vaccines & Prevention B.V. |
Yes
|
| NCT04351685 |
TZA
|
Ifakara Health Institute; Dar es Salaam;
|
Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants |
Interventional |
Phase 3
|
Mycobacterium Tuberculosis Infection
|
2020-11-09 |
2025-06-10 |
Serum Institute of India Pvt. Ltd. |
No
|
| NCT00849017 |
|
|
Safety and Efficacy Study of Albiglutide in Type 2 Diabetes |
Interventional |
Phase 3
|
Diabetes Mellitus, Type 2
|
2009-01-01 |
2013-02-01 |
GlaxoSmithKline |
No
|
| NCT02317562 |
TUN
|
Hopital Militaire; Tunis;
|
Efficacy and Safety Study of I10E in the Maintenance Treatment of Patients With CIDP: Extension of PRISM Study I10E-1302 |
Interventional |
Phase 3
|
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
|
2015-11-01 |
2017-07-28 |
Laboratoire français de Fractionnement et de Biotechnologies |
No
|
| NCT00553631 |
TUN
|
La Rabta hospital Tunis; Tunis;
|
Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) ERT Compared With Imiglucerase in Type I Gaucher Disease |
Interventional |
Phase 3
|
Gaucher Disease, Type 1
|
2008-01-29 |
2009-05-05 |
Shire |
No
|
| NCT04411082 |
TZA, ZAF, NGA, BWA, EGY, ETH, GHA, Uganda, NAM, TUN
|
Handeni Town Council; Handeni;
Department of Haematology and Cell Biology - University of the Free State; Bloemfontein;
City Park Medical Centre; Cape Town;
Department of Radiotherapy - Addington Hospital; Durban;
Irrua Specialist Teaching Hospital; Edo;
Independence Surgery; Gaborone;
Baheya Hospital; Cairo;
Hawassa University Referral Hospital; Awassa;
Abu Rish Children's Hospital; Cairo;
Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region;
Skin and Hair care Centre; Cape Town;
Faculty of Medicine - Zagazig University; Zagazig;
Baylor College of Medicine Children's Foundation; Kampala;
Health Insurance Hospital; Cairo;
PAREXEL Port Elizabeth; Port Elizabeth;
Windhoek Central Hospital; Wanaheda Zone;
Constantiaberg Haematology; Cape Town;
The College; Cape Town;
Hospital Aziza Othmana; Tunis;
The Oncology Centre - Onco Care Specialist Oncologists; Durban;
Tara Hospital; Cape Town;
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse;
Centre National de Greffe de Moelle Osseuse; Tunis;
Hôpital d'enfants; Tunis;
Botswana - University of Pennsylvania; Gaborone; (Upenn)
Kimberley Hospital Complex; Kimberley;
Rondebosch Oncology Centre - CancerCare; Cape Town;
Netcare Moot General Hospital; Pretoria;
Jubilee Hospital; Gauteng;
|
A Study of IMR-687 in Subjects With Beta Thalassemia |
Interventional |
Phase 2
|
β Thalassemia
|
2020-10-16 |
2022-05-01 |
Imara, Inc. |
No
|
| NCT03366259 |
|
|
Prostaglandins Before Caserean Section |
Interventional |
Phase 2,Phase 3
|
Intrapartum Hemorrhage
|
2017-12-01 |
2018-02-01 |
Kasr El Aini Hospital |
No
|
| NCT04349384 |
BDI
|
Institut National d'Oncologie; Bujumbura;
|
Audit of Surgery for Colorectal Cancer |
Observational |
|
Colon Adenocarcinoma,Rectal Adenocarcinoma
|
2018-01-01 |
2019-12-31 |
Institut National d'Oncologie, Morocco |
No
|
| NCT00413218 |
ZAF
|
Netcare Unitas Hospital; Centurion;
|
Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections |
Interventional |
Phase 3
|
Mycoses,Candidemia,Candidiasis, Invasive
|
2007-03-08 |
2015-03-03 |
Astellas Pharma Inc |
No
|
| NCT02943213 |
ZAF
|
Farmovs Intergrated Research Solutions; Bloemfontein;
|
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride |
Interventional |
Phase 1
|
Anti-Psychotic,Treatment of Schizophrenia,Control Nausea and Vomiting,Acute Intermittent Porphyria,Relief of Intractable Hiccups,Adjunct in the Treatment of Tetanus,Management of Manifestations of Psychotic Disorders,Relief of Restlessness and Apprehension Before Surgery,Control Manifestations of the Manic Type of Mani-depressive Illness
|
2016-11-01 |
2016-12-01 |
Cycle Pharmaceuticals Ltd. |
No
|
| NCT04841577 |
BFA
|
Investigational Site Number 2040001; Cotonou;
|
A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 60 Years and Above |
Interventional |
Phase 3
|
Respiratory Syncytial Virus Infections
|
2021-04-27 |
2022-03-08 |
GlaxoSmithKline |
No
|
| NCT04374682 |
EGY
|
Assiut University; Assiut;
|
Effectiveness of a Home Based Exercise Program on Temporomandibular Dysfunction Syndrome |
Observational |
|
Temporomandibular Disorder
|
2020-03-01 |
2020-06-30 |
Assiut University |
No
|
| NCT01562132 |
KEN
|
Family AIDS Care and Education Services; Kisumu; (FACES)
|
Safety Study of Fluconazole in Combination With Flucytosine for the Treatment of Early Cryptococcal Infection |
Interventional |
Phase 2
|
Cryptococcal Infection Disseminated
|
2013-09-01 |
2014-07-01 |
Yale University |
No
|
| NCT04290975 |
NGA
|
Aminu Kano Teaching Hospital; Kano; (AKTH)
Ahmadu Bello University Teaching Hospital; Zaria; (ABUTH)
|
Bridging the Childhood Epilepsy Treatment Gap in Africa |
Interventional |
Not Applicable
|
Epilepsy
|
2020-06-19 |
2024-07-01 |
Vanderbilt University Medical Center |
No
|
| NCT03963336 |
EGY
|
Fayoum University Hospital; Fayoum;
|
Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial Hypertension |
Interventional |
Early Phase 1
|
Idiopathic Intracranial Hypertension
|
2017-07-22 |
2018-08-02 |
Fayoum University |
No
|
| NCT03853824 |
|
|
African Surgical OutcomeS-2 (ASOS-2) Trial |
Interventional |
Not Applicable
|
Surgery,Morality
|
2019-05-06 |
2020-07-31 |
University of Cape Town |
No
|
| NCT02951429 |
ZAF
|
Milpark Hospital; Johannesburg;
|
Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary Hypertension |
Interventional |
Phase 2
|
Idiopathic Pulmonary Fibrosis
|
2016-12-31 |
2020-08-22 |
Hoffmann-La Roche |
No
|
| NCT01380444 |
|
|
Intramedullary Nail Versus Sliding Hip Screw Inter-Trochanteric Evaluation |
Interventional |
Not Applicable
|
Femoral Neck Fractures,Intertrochanteric Fracture
|
2011-12-01 |
2017-03-01 |
Stryker Trauma GmbH |
No
|
| NCT03302338 |
EGY
|
Ain Shams University; Cairo;
|
Simulated Amniotic Fluid Solution in Neonates Recovering From GIT Surgeries |
Interventional |
Phase 1
|
Necrotizing Enterocolitis
|
2015-07-01 |
2018-10-01 |
Rania Ali El-Farrash |
No
|
| NCT01743417 |
|
|
Computerized Cognitive Rehabilitation in Children After Severe Malaria |
Interventional |
Not Applicable
|
Malaria
|
2011-04-01 |
2016-08-23 |
Makerere University |
No
|
| NCT02214095 |
EGY
|
Ain Shams University; Cairo;
|
Glucosamine Periodontal Adjunctive Therapy |
Interventional |
Early Phase 1
|
Chronic Periodontitis
|
2012-01-01 |
2013-02-01 |
Ain Shams University |
No
|
| NCT03772470 |
TZA
|
Ifakara Health Institute; Dar es Salaam;
|
Use of Airtime Amounts to Improve Interactive Voice Response Surveys in Colombia and Tanzania |
Interventional |
Not Applicable
|
Noncommunicable Diseases,Surveys and Questionnaires
|
2018-08-09 |
2018-11-13 |
Johns Hopkins Bloomberg School of Public Health |
No
|
| NCT04419701 |
ZAF
|
Tara Hospital; Cape Town;
|
Comparison of Ultrasound Guided Genicular Nerve Block and Periarticular Infiltration in Knee Arthroplasty |
Interventional |
Not Applicable
|
Postoperative Pain
|
2020-06-30 |
2021-01-01 |
Tanta University |
No
|
| NCT02214875 |
NGA
|
Center for Integrated Health Programs; Abuja; (CIHP)
|
Lafiyan Jikin Mata "Excellent Health for Mothers" |
Interventional |
Not Applicable
|
Retention
|
2014-07-01 |
2017-03-01 |
Centre for Integrated Health Programs, Nigeria |
No
|
| NCT03388021 |
EGY
|
Mansoura University Hospitals; Mansoura;
|
A Trial Comparing Routine Versus Selective Use of Completion Angiography After Surgical Thromboembolectomy in the Treatment of Acute Lower Limb Ischemia and Their Impacts on Limb Salvage Rates |
Interventional |
Not Applicable
|
Acute Limb Ischemia
|
2015-03-02 |
2018-02-04 |
Mansoura University |
No
|
| NCT00111787 |
|
|
Study Of Lapatinib In Combination With Paclitaxel In The Treatment Of Newly Diagnosed Inflammatory Breast Cancer |
Interventional |
Phase 2
|
Neoplasms, Breast
|
2005-04-11 |
2006-11-01 |
GlaxoSmithKline |
No
|
| NCT03235648 |
EGY
|
Oncology Centre - Mansoura University Hospitals; Mansoura;
|
Evaluation of Surgical Excision of Cardiophrenic Lymph Nodes in Patients With Advanced Ovarian Cancer |
Interventional |
Not Applicable
|
Ovarian Cancer
|
2017-06-01 |
2023-06-01 |
Mansoura University |
No
|
| NCT02735655 |
EGY, Egypt
|
Faculty of Medicine - Zagazig University; Zagazig;
Al-Azhar University; Cairo;
|
Global State of Digestive Endoscopy Training Survey |
Observational |
|
Gastrointestinal Endoscopy Training
|
2016-04-01 |
2017-03-01 |
Al-Azhar University |
No
|
| NCT03551444 |
EGY
|
Ain Shams University; Cairo;
|
Recurrence Rate of Hepatocellular Carcinoma After Treatment of Chronic Hepatits C Patients With Direct Acting Antivirals: Randomized Controlled Phase 3 Trial |
Interventional |
Phase 3
|
Hepatitis C, Chronic,Hepatocellular Carcinoma
|
2017-10-01 |
2019-10-01 |
Ain Shams University |
No
|
| NCT03604913 |
EGY
|
Assiut University; Assiut;
|
Aortic Valve Sparing Root Replacement Versus Bentall |
Interventional |
Not Applicable
|
Aortic Root Aneurysm,Aortic Root Dissection
|
2019-02-01 |
2021-10-01 |
Assiut University |
No
|
| NCT02676011 |
MLI
|
Faculty of Medicine - University of Bamako; Bamako;
|
Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic Surgery |
Interventional |
Phase 2
|
Bradycardia
|
2016-02-01 |
2016-05-01 |
Assiut University |
No
|
| NCT03929705 |
|
|
Assessing the Ability of the T-SPOT®.TB Test |
Observational |
|
Tuberculosis (TB)
|
2019-05-02 |
2020-09-30 |
Oxford Immunotec |
No
|
| NCT04186741 |
EGY
|
Assiut University; Assiut;
|
Inner and Middle Ear Effects of Hyperbaric Oxygen Thrapy |
Observational |
|
Otitic Barotrauma
|
2021-04-01 |
2022-06-01 |
Assiut University |
No
|
| NCT04167566 |
GHA
|
Virology Department - Noguchi Memorial Institute For Medical Research University Of Ghana; Legon; (NMIMR)
|
Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children |
Interventional |
Not Applicable
|
Malaria,Malaria, Asymptomatic Parasitaemia
|
2017-07-01 |
2019-07-30 |
Noguchi Memorial Institute for Medical Research |
No
|
| NCT00490568 |
|
|
Open-Label Extension Study Of Rosiglitazone XR As Adjunctive Therapy In Subjects With Mild-to-Moderate Alzheimers |
Interventional |
Phase 3
|
Alzheimer's Disease
|
2007-08-08 |
2009-06-01 |
GlaxoSmithKline |
No
|
| NCT03266978 |
EGY
|
Assiut University; Assiut;
|
Impact of Glycemic State on Patients ST Elevation Myocardial Infarction With Primary Percutaneous Coronary Angioplasty |
Observational |
|
ST Elevation Myocardial Infarction
|
2018-01-01 |
2019-07-01 |
Assiut University |
No
|
| PACTR202007828853091 |
ZAF
|
BioART Fertility Centre; Johannesburg;
|
STEM CELLS FOR OVARIAN REJUVENATION (The SCORE trial) |
RCT |
|
Obstetrics and Gynecology
|
20-01-08 |
70-01-01 |
Oxford road Day clinic |
No
|
| NCT03049917 |
KEN
|
Kisumu County Hospital; Kisumu;
|
Financial Incentives to Increase Pediatric HIV Testing |
Interventional |
Not Applicable
|
HIV
|
2017-01-31 |
2018-10-01 |
University of Washington |
No
|
| NCT04240990 |
NGA
|
Lagos University Teaching Hospital; Idi Araba;
|
Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition |
Interventional |
Not Applicable
|
Tuberculosis,Severe Acute Malnutrition
|
2019-11-04 |
2020-11-04 |
Institut National de la Santé Et de la Recherche Médicale, France |
No
|