The COVID-19 pandemic across Africa in numbers
Burden of COVID-19 in Africa
COVID-19 Clinical Trial Landscape in Africa
Institutions conducting Covid-19 Clinical Trials in Africa
African regulatory and ethics processes during Covid-19 pandemic.
National regulatory authorities and national ethics committees from across Africa have agreed to combine their expertise to expedite clinical trial review and approvals for new multinational preventive, diagnostic and therapeutic interventions to the COVID-19 pandemic.
Proposed new timelines will be 10 days for repurposed therapeutics and 15 days for novel drugs and vaccines. Find more information here:
WHO- AFRO conducted a survey to map current resources and processes for protocol submission and approval across member states.
African Covid-19 Trial Data
| Trial ID | Location | Facility | Brief Title | Study Type | Study Phase | Condition | Start Date | Completion Date | Lead Sponsor Name | Covid Research |
|---|---|---|---|---|---|---|---|---|---|---|
| NCT04188327 | Egypt, EGY |
Faculty of Medicine - Fayoum University; Faiyum; Faculty of Medicine - Tanta University;Tanta: University Hospital - Tanta University; Tanta; |
Stellate Ganglion Block in Herpes Zoster | Interventional | Not Applicable | Pain,Neuropathic | 2020-05-01 | 2022-10-01 | Tanta University | No |
| NCT04863144 | ZAF |
The Oncology Centre - Onco Care Specialist Oncologists; Durban; |
Pharmacokinetics of Paclitaxel in Correlation With Adverse Events in Cancer Patients With and Without Liver Impairment | Observational | Liver Diseases | 2020-08-01 | 2022-02-01 | Ain Shams University | No | |
| NCT04493216 | A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults | Interventional | Phase 2 | HIV Infections | 2020-11-18 | 2028-10-23 | ViiV Healthcare | No | ||
| NCT05538182 | ZWE |
University of Zimbabwe; Harare; |
Zimbabwe Eyecare And Learning(ZEAL):Formative Research on Hyperopia and Educational Outcomes in Primary School Children | Interventional | Not Applicable | Hyperopia,Long Sight | 2022-09-01 | 2024-12-31 | Queen's University, Belfast | No |
| PACTR202008763735746 | Pericapsular Nerve Group (PENG) Block for Hip Fracture; a prospective randomized controlled trial | RCT | perioperative analgesia for hip fracture surgery | 1970-01-01 | 1970-01-01 | Tanta University Faculty of Medicine | No | |||
| NCT01619540 | Valsalva Manœuvre in the Diagnosis of Left Ventricular Failure in Chronic Obstructive Pulmonary Disease Exacerbation | Interventional | Not Applicable | COPD Exacerbation,Acute Heart Failure | 2011-05-01 | 2013-06-01 | University of Monastir | No | ||
| NCT05158348 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine | Interventional | Phase 3 | Lidocaine,Tonsillectomy,Dexmedetomidine | 2021-11-05 | 2022-04-15 | Kasr El Aini Hospital | No |
| PACTR201405000815100 | TZA |
Nyamagana District Hospital; Mwanza; |
Effectiveness of an alcohol-focused intervention in improving adherence to antiretroviral therapy (ART) and HIV treatment outcomes | RCT | Infections and Infestations | 2014-03-11 | 1970-01-01 | Medical Research Council of South Africa | No | |
| NCT05494749 | Zirconia Reinforced Glass Ionomer in MIH | Interventional | Not Applicable | Molar Incisor Hypomineralization | 2022-09-01 | 2023-12-30 | Hams Hamed Abdelrahman | No | ||
| NCT05254561 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Triple Antigen vs Monoantigen Immunotherapy for Warts | Interventional | Phase 2,Phase 3 | Triple Intralesional Immunotherapy Combination in Multiple Recalcitrant Warts | 2020-11-20 | 2021-11-15 | Zagazig University | No |
| NCT05382247 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Ultrasonographic Assessement Of Diaphragm In Neuromuscular Diseases In Pediatric Patients | Interventional | Not Applicable | Ultrasonographic Assessement Of Diaphragm In Neuromuscular Diseases In Pediatric Patients | 2022-05-13 | 2023-05-13 | Sohag University | No |
| NCT04979936 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Early Laparoscopic Cholecystectomy Versus Percutaneous Cholecystostomy in Grade II Acute Cholecystitis Guidelines | Interventional | Not Applicable | Acute Cholecystitis,Empyema, Gallbladder | 2016-01-01 | 2021-01-31 | Alexandria University | No |
| NCT04864288 | ZAF |
New Specialist Outpatient Department; Cape Town; |
Value of Penile Elastography in Diagnosis of Patients With Erectile Dysfunction and Non-responders to Intra-corporal Injection | Observational | To Investigate the Value of Penile Elastography in the Diagnosis of Fibrosis of CC | 2019-09-28 | 2020-04-30 | Ramzy Raafat Mohamed Mohamed Elnabarawy, MD, MSc, MRCS | No | |
| NCT01868737 | ZAF |
Tygerberg Hospital; Parrow; |
Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature Infants | Interventional | Phase 3 | Necrotizing Enterocolitis | 2011-07-01 | 2012-08-01 | University of Stellenbosch | No |
| PACTR201903678270105 | NGA |
Lagos University Teaching Hospital; Idi Araba; |
Comparison of Astigmatic Effects of Sutured Graft Versus Use of Autologous Blood Fibrin in ConjunctivalAutografting Following Pterygium Excision | RCT | Eye Diseases | 2018-01-03 | 1970-01-01 | Ajagbe Ibrahim Kayode | No | |
| NCT05494281 | MAR |
Specialty Hospital of Rabat; Rabat; |
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pan in Breast Cancer | Interventional | Not Applicable | Pain, Chronic,Breast Neoplasms,Pain, Postoperative,Post-Mastectomy Chronic Pain Syndrome | 2022-08-01 | 2023-07-31 | Moroccan Society of Surgery | No |
| PACTR201310000683408 | Safety And Immunogenicity Of Novel Candidate Blood-Stage Malaria Vaccine P27A : Phase Ia/Ib | RCT | Infections and Infestations | 2014-01-01 | 1970-01-01 | Centre Hospitalier Universitaire Vaudois | No | |||
| NCT05320731 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Atomization vs. Nebulization for Airway Topicalization During Awake Nasotracheal Fiberoptic Intubation | Interventional | Not Applicable | Awake Fiberoptic Intubation | 2022-02-20 | 2022-06-20 | Zagazig University | No |
| NCT04650113 | EGY |
NEMROCK Faculty of Medicine - Cairo University; El Azab; |
Clinical and Radiographic Assessment of Partial and Complete Pulpotomy in Primary Molars Using MTA | Interventional | Phase 1,Phase 2 | Pulp Disease, Dental | 2021-01-20 | 2021-09-03 | Cairo University | No |
| NCT01386138 | Treating South African Pregnant Women for Methamphetamine | Interventional | Not Applicable | HIV,Drug Addiction | 2011-07-01 | 2013-06-01 | RTI International | No | ||
| NCT05290766 | EGY, SEN |
Mansoura University Hospitals; Mansoura; El Hadji Ibrahima Niass Hospital; Kaolack; |
Two Versus Four Implant-supported Fixed Full-arch Prosthesis | Interventional | Not Applicable | Prosthesis Durability | 2022-01-04 | 2023-08-01 | Mansoura University | No |
| NCT02103452 | Egypt |
Al-Azhar University; Cairo; |
Edessy Stem Cell Score (ESS), Endometrium, Endometrioma | Interventional | Not Applicable | Endometriosis, Ovarian | 2012-10-01 | 2013-10-01 | Al-Azhar University | No |
| NCT05223738 | EGY |
Kasr El-Aini Hospital - Kasr El Aini Faculty of Medicine Cairo University; El Azab; |
Resident Memory T Cells in Vitiligo | Observational | Vitiligo | 2020-12-31 | 2022-02-01 | Kasr El Aini Hospital | No | |
| NCT03324009 | NGA |
Princess Marina Hospital; Port Harcourt; |
2-stage Cervical Cancer Screening in Botswana | Interventional | Not Applicable | HIV/AIDS,Cervical Cancer | 2018-04-20 | 2020-01-31 | Beth Israel Deaconess Medical Center | No |
| NCT03276273 | Bispectral-Electroencephalography (EEG) in First Time Hemodialysis | Observational | Renal Failure Acute Chronic | 2017-05-01 | 2023-12-01 | Suez Canal University | No | |||
| NCT00074152 | Adjuvant Chemotherapy in Treating Women Who Have Undergone Resection for Relapsed Breast Cancer; Chemotherapy as Adjuvant for LOcally Recurrent Breast Cancer | Interventional | Phase 3 | Breast Cancer | 2002-07-01 | 2016-08-22 | International Breast Cancer Study Group | No | ||
| PACTR202101499206800 | the HANDS HPV Vaccine Trial | RCT | Cancer,Infections and Infestations | 2019-01-07 | 1970-01-01 | Medical Research Council Unit The Gambia at LSHTM | No | |||
| NCT04424316 | EGY, Senegal, BWA, ZMB, South Africa, ZAF, TUN, KEN, SEN, Ghana, Nigeria, Benin, Ethiopia, GMB, Uganda, COD, Tunisia, DZA, UGA, ZWE, NGA, Kenya, GHA, MOZ, Egypt, NAM, Togo, Algeria, LBR, Zambia, CMR, MWI |
Clinical Research Center - Cairo University; Giza; University of Thies; Thies; (UT) BHP Study Clinic Gaborone Shapiro - Princess Marina Hospital; Gaborone; (CRS) Francistown Academic Hospital; Francistown; Ipafu Rural Health Centre; Copperbelt; TASK Central Clinical Research Centre; Bellville; Choma District Health Office; Choma; Synopsis Research; Claremont; Clintrial Consultants; Cape Town; Centre for Medical Excellence; Sandton; Queenswood CTC; Pretoria; The Military hospital of Tunis; Tunis; Department of Paediatrics - Alupe University College; Busia; First Care Medical Centre; Soweto; Mediclinic Sandton; Bryanston; Maternal Adolescent and Child Health - School of Public Health University of Witwatersrand; Johannesburg; (MatCH Wits) Empilweni TB Hospital; Port Elizabeth; Centre Hospitalier Universitaire - Hopital Aristide Le Dantec; Dakar; (CHU) Netcare St. Augustine's Hospital; Durban; Louis Pasteur Hospital; Pretoria; University of Ghana; Accra; Service de Medicine Interne - Hôpital la Rabta; Tunis; Wilmed Park Hospital; Klerksdorp; Melrose House; Cape Town; Aminu Kano Teaching Hospital; Kano; (AKTH) Kotopounga primary school; Natitingou; Faculty of Physical Therapy - Pharos University; Alexandria; Cape Gate Oncology Centre - Cancercare; Brakenfell Iatros International; Bloemfontein; Department of Paediatrics and Child Health; Panorama; Urban Comprehensive Health Centre; Ile Ife; Engelbrecht Research Limited; Centurion; Mekelle University; Mek'ele; Clinical Projects Research; Worcester; Sukuta Health Center; Brikama; Allergology Diagnostic Clinical Research Centre; Western Cape; (ADCRU) Joint Clinical Research Center; Lubowa; City Park Medical Centre; Cape Town; Gatesville Medical Centre; Cape Town; General Reference Hospital Mushie Hospital; Bandundu; (HGR) Manor Medical Center; Sandton; Cardiology Clinical Research; Alberton; University of the Free State; Bloemfontein; Department of Radiotherapy - Addington Hospital; Durban; Steve Biko Academic Hospital - University of Pretoria; Pretoria; Medi-clinic Panorama Heart and Lung Unit - Medi-Clinic Panorama; Parow; Nelson Mandela Academic Clinical Research Unit - Nelson Mandela Academic Hospital; Mthatha;(NeMACRU) Wits RHI Shandukani Research Centre CRS; Johannesburg; (RHI) Africa Health Research Institute; Durban; (AHRI) Hospital Charles Nicolle; Tunis; Mary Potter Oncology Centre; Pretoria; Wellcome Centre for Infectious Diseases Research in Africa - University of Cape Town; Observatory; Pediatric Department - Mansoura University Hospitals; Mansoura; Boland Ethical Research Group; Western Cape; Mbale Regional Referral Hospital; Mbale; Global Clinical Trials; Pretoria; Scion Clinical Research; Pretoria; Cooper University Hospital Clinical Research Site; Durban; Rahima Moosa Mother and Child Hospital; Johannesburg; Western Cape Clinical Trials; Western Cape; Life Flora Clinic; Roodepoort; Southern Cross Hospital; Cape Town; Enhancing Care Foundation; Durban; Poli Clinic; Port Elizabeth; Clinical Research Center of Butembo - Catholic University of Graben; Butembo; Cairo University Hospital; Cairo; Centre Hospitalier du Mont-Amba; Kinshasa; Montana Hospital; West Coast; Murtala Muhammad Specialist Hospital; Kano; Kar Geno Center Kisumu Women Center For Hope; Kisumu; Uganda Virus Research Institute - International AIDS Vaccine Initiative HIV Vaccine Program; Entebbe; (UVRI-IAVI CRS) Deborah Retief Memorial Hospital; Mochudi; Abu Rish Children's Hospital; Cairo; Practice Prof. Y Elhawary - AlSalama Hospital; Cairo; South Medical Hospital; Chitungwiza; New Specialist Outpatient Department; Cape Town; Center for Clinical Care and Clinical Research; Abuja; (CCCRN) University of Cape Coast; Cape Coast; Mount Kenya University Trust; Thika; (MKU) School of Public Health Research Centre - University of Health and Allied Sciences; Ho Volta; (SPH UHAS) Drs Gudgeon and Boeddinghaus Associates; Cape Town; Intercare Tyger Valley Healthcare Centre; Bellville; George Clinical Study Site; George; University of Botswana/McMAsters University; Gaborone; Consultorio Medico Esperanza; Chimoio; Helderberg Clinical Research Centre; Somerset West; Health Insurance Hospital; Beni Suef; Department of Clinical Pharmacy and Pharmacy Management - Nnamdi Azikwe University; Awka; Newlands Clinic; Harare; St. George's Medical Centre; Port Elizabeth; JOSHA Research; Bloemfontein; Kenyatta University Teaching Referral and Research Hospital; Kahawa West; Pumwani Maternity Hospital; Nairobi; Winelands Medical Research Centre; Cape Winelands; Clinical Research Center - Faculty of Medicine Ain Shams University Research Institute; El Mohamady; The Oncology Centre - Onco Care Specialist Oncologists; Durban; Dr George Mukhari Academic Hospital; Ga-Rankuwa; Genelin Clinical Trials; Free State; Cosmos Medical Centre; Mpumalanga; Centre Hospitalo universitaire Bologhine Hospital; Algiers; Department of Endocrinology - Old Main Building, Groote Schuur Hospital; Cape Town; St. James's Hospital Life Health; East London; Central Primary Health Centre; Akahia; St. Mary's Clinical Research Site -The University of Zimbabwe College of Health Sciences Clinical Trials Research Centre; Harare; (UZCHS-CTRC) Bondo Clinic - Bondo District Hospital; Bondo; Dr Rory Callaghan Inc; Durban; Africa University Clinical Research Centre; Mutare; (AUCRC) Cooper Centre; Durban; Paediatric Infectious Diseases Clinical Research Unit; Cape Town; (KID-CRU) Medical Research Council Uganda Virus Research Institute Research Unit on AIDS; Entebbe; Lung Infection And Immunity Unit - University of Cape Town; Cape Town; Medicross Medical Centre Eldoraigne; Centurion; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; Faculty of Medicine - Minia University; El Menia; East Central Hospital; Windhoek; Medpark; Cape Town; Universite de Medecine et Science de la Sante; Dakar; Noguchi Memorial Institute for Medical Research; Accra; (NMIMR) Khayelitsha Clinical Research site; Khayelitsha; (CRS) University Of Lome; Lome; Hospital Central de l'Armée; Algiers; (HCA) Tygerberg Hospital; Parrow; Aswan Heart Center; Aswan; Health and Wellness Clinic; Pretoria; Society for Family Health Headquarters; Port Harcourt; Thomo Clinic; Limpopo; Khayelitsha Ekhayavac Clinic; Khayelitsha; Scottish Livingstone Hospital; Molepolole; Centre Hospitalo-Universitaire de Constantine; Constantine; (CHU) Department of Internal Medicine - University of Cape Town; Cape Town; Fairfield Medical Suites; Clairemont; Respiratory and Meningeal Pathogens Research Unit; Soweto; (RMPRU) Jackson F. Doe Memorial Hospital; Tapeta; Hôpital d'enfants; Tunis; Medical and Dental Centre; Randburg; Hiway Medical Center; Durban; Centre for Infectious Disease Research; Lusaka; (CIDRZ) The Aga Khan University Hospital; Nairobi; Instituto Nacional de Saúde; Maputo; (INS) Botswana - University of Pennsylvania; Gaborone; (Upenn) Medicross Bluff Medical Center; Durban; Limbe Health Center; Sud-Ouest; Blantyre Clinical Research Site; Blantyre; (CRS) Johese Clinical Research; Centurion; Netcare N1 City Hospital; Cape Town; Ain Shams University; Cairo; Walter Sisulu University HIV Vaccine Research Unit CRS; Mthatha; Intercare Medical and Dental Centre; Lynwood; Skin Avenue Clinic; El Salam El Sharkaia; School of Medicine - Moi University; Eldoret; Moriana Clinical Research; Free State; Ndola District Health Management Board; Ndola; Netcare Moot General Hospital; Pretoria; Military Hospital; Accra; Bertoni Mercy Clinic; Pretoria; Beitbridge District Hospital; Beitbridge; Gaborone Clinical Research Site; Gaborone; Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; Department of Paediatrics and Child Health - University of Ilorin Teaching Hospital; Ilorin; Damien Foundation; Abuja; Consortium for Health Research and Advanced Training - University of Nigeria; Enugu; (CHERAT) Mont Amba Medical Center - University of Kinshasa; Lemba; Mulanda Health Centre IV; Tororo; Limpopo Clinical Research Initiative; Limpompo; University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF) Center for Integrated Health Programs; Abuja; (CIHP) University of California San Francisco - Kenya Medical Research Institute; Kisumu; (UCSF-KEMRI) Marondera Provincial Hospital; Harare; Eastern Cape Oncology Center; Port Elizabeth; |
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy. | Interventional | Phase 3 | Respiratory Tract Infection | 2020-06-17 | 2023-11-12 | Pfizer | No |
| NCT01151189 | Efficacy Against TB Disease, Safety, and Immunogenicity of MVA85A/AERAS-485 in HIV-Infected Adults (C-030-485) | Interventional | Phase 2 | Tuberculosis,HIV Infections | 2011-07-01 | 2014-09-01 | Aeras | No | ||
| NCT05437939 | Uganda |
Makerere University; Kampala; |
Adverse Outcomes Following Female Genital Fistula Repair | Observational | Incontinence,Female Genital Fistula | 2022-05-20 | 2026-02-01 | University of California, San Francisco | No | |
| NCT01582763 | TUN |
Hospital Militaire; Montfleury; |
International Guillain-Barré Syndrome Outcome Study | Observational | Miller Fisher Syndrome,Guillain-Barré Syndrome | 2012-05-01 | 2024-09-01 | Erasmus Medical Center | No | |
| NCT01673360 | ZAF |
The Urology Hospital; Pretoria; |
Collection of Long Term Patient Outcomes Data Following Implantation of AMS Surgical Devices | Observational | Pelvic Organ Prolapse,Female Stress Incontinence | 2012-09-01 | 2021-12-01 | ASTORA Women's Health | No | |
| PACTR202206754734018 | Safety & Immunogenicity of Fractional Doses of Vaccines Among Nigerian Adults- A Randomised Non-Inferiority Triple Blind Trial | RCT | Infections and Infestations | 1970-01-01 | 1970-01-01 | Nigeria Federal Ministry of health | No | |||
| NCT05314569 | EGY |
Watany Research and Development Center - Watany Eye Hospital; Cairo; (WEH) |
Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics | Interventional | Phase 1 | Anesthesia | 2022-04-15 | 2022-09-25 | Cairo University | No |
| NCT04593303 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Internal Iliac Artery Ligation During Management of Placenta Accreta Spectrum | Interventional | Not Applicable | Placenta Accreta | 2020-09-01 | 2022-01-01 | Mansoura University Hospital | No |
| NCT05275270 | GHA |
Korle Bu Teaching Hospital; Accra; |
Role of Topical Oxytocin Gel in Post-Menopausal Women | Interventional | Not Applicable | Menopause Related Conditions | 2020-12-01 | 2021-05-31 | Al-Azhar University | No |
| NCT05023395 | EGY |
The Cairo Kidney Center; Cairo; |
Safety and Efficacy of MEE-HU Medicus | Interventional | Phase 2 | Urinary Tract Infections | 2021-10-11 | 2023-10-11 | Dr. Ahmed Ismail | No |
| NCT04981990 | EGY |
Ain Shams University; Cairo; |
Single Lung Ventilation Versus Two Lung Ventilation | Interventional | Not Applicable | Hypoxemia,Single Lung Ventilation | 2021-03-01 | 2021-08-25 | Ain Shams University | No |
| NCT04505293 | ZAF, UGA |
Hiway Medical Center; Durban; Mbarara Regional Referral Hospital; Mbarara; |
Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas | Interventional | Not Applicable | Head Trauma,Trauma, Head,Head Injuries,Injuries, Head,Head Injury Major,Head Injury, Open,Head Injury, Minor,Head Trauma Injury,Head Trauma,Closed,Multiple Head Injury,Crushing Skull Injury,Head Injuries, Closed,Craniocerebral Injuries,Head Injuries, Multiple,Head Trauma, Penetrating,Injuries, Craniocerebral | 2021-10-05 | 2022-08-05 | Duke University | No |
| NCT05483959 | MAR |
Hôpital Cheikh Khalifa Bin Zayed Al Nahyan; Casablanca; |
BIPAP in the Management of Acute Respiratory Distress Syndrome | Interventional | Not Applicable | Mechanical Ventilation Complication | 2019-04-20 | 2022-07-22 | South Valley University | No |
| PACTR201901684344569 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
effect of different squatting exercises on primary dysmenorrhea | RCT | Obstetrics and Gynecology | 1970-01-01 | 1970-01-01 | Mahitab Mohamed Yosri | No | |
| NCT03035305 | Mali |
AMCP-ALIMA Hospital; Kolokani |
Seasonal Malaria Chemoprevention With or Without Lipid-based Nutrient Supplement in Children Aged 6-59 Months in Mali | Interventional | Not Applicable | Malaria | 2016-08-01 | 2016-11-01 | Alliance for International Medical Action | Yes |
| NCT04765254 | NGA |
Lagos University Teaching Hospital; Idi Araba; |
COVID-19 Infection in Diabetic Patients | Observational | Covid19,Chest CT Scan,Diabete Type 2,Non Diabetic Patients | 2021-02-20 | 2021-04-10 | Cairo University | Yes | |
| NCT05274711 | MAR |
International Hospital of Cheikh zaid; Rabat; |
The Effect of Whole Body Vibration on Neck Disability and Proprioception in Patients With Forward Head Posture | Interventional | Not Applicable | Forward Head Posture | 2022-07-01 | 2023-02-01 | Cairo University | No |
| NCT03637985 | Egypt |
Al-Azhar University; Cairo; |
Effect of 12 Weeks of Resistive Exercises Versus Aerobic Exercises in Overweight Hypertensive Postmenopausal Women | Interventional | Not Applicable | Exercise | 2017-09-01 | 2018-08-01 | Cairo University | No |
| NCT04823767 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Single Anastomosis Sleeve Iejenal Bypass in Obese Patient With Hiatus Hernia | Interventional | Not Applicable | Obesity, Morbid | 2020-04-12 | 2021-03-15 | Minia University | No |
| NCT04565184 | ZAF |
National District Hospital; Bloemfontein; |
Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde | Interventional | Phase 4 | Malaria,Falciparum | 2019-05-09 | 2020-11-30 | University of Yaounde 1 | No |
| NCT03007316 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Evaluation of Esthetics Around Immediate Implants in VIP - CT Grafted vs Non-grafted Sites.RCT | Interventional | Not Applicable | Buccal Bone Loss in Immediate Implants | 2017-01-23 | 2020-03-12 | Cairo University | No |
| NCT04710303 | ZAF |
Khayelitsha Clinical Research site; Khayelitsha; (CRS) |
COVID-19 Vaccination Using a 2nd Generation (E1/E2B/E3-Deleted) Adenoviral Platform in Healthy South African Adults | Interventional | Phase 1 | Covid19 | 2021-03-02 | 2022-04-01 | ImmunityBio, Inc. | Yes |
| NCT05294718 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
: External Shunt Versus Internal Shunt for Off Pump Glenn | Interventional | Not Applicable | Cerebral Ischemia | 2017-06-01 | 2022-08-01 | Kasr El Aini Hospital | No |
| NCT01218581 | EGY |
Mansoura University Hospitals; Mansoura; |
Aromatase Inhibitors or GnRH-a for Uterine Adenomyosis | Interventional | Phase 2,Phase 3 | the Efficacy of Aromatase Inhibitor vs. Gonadotrpins Releasing Hormone Agonists in Treating Premenopausal Women With Uterine Adenomyosis | 2005-12-01 | 2010-01-01 | Mansoura University | No |
| NCT05079048 | MAR |
Military Hospital Mohamed V; Rabat; |
PEEK Retentive Elements Versus Conventional | Interventional | Not Applicable | Partially Edentulous Mandible | 2017-07-01 | 2019-11-30 | Cairo University | No |
| NCT05047614 | EGY |
University Hospital - Tanta University; Tanta; |
Effects of Lumbar Repositioning Feedback and Transversus Abdominis Training on Lumbar Propricption in Patients With Chronic Mechanical Low Back Pain | Interventional | Not Applicable | Orthopedic Disorder | 2020-04-19 | 2022-08-15 | October 6 University | No |
| NCT04558554 | KEN |
Clinical Research Annexe - Kenya Medical Research Institute; Siaya; (KEMRI) |
Pharmacy Delivery to Expand the Reach of PrEP in Kenya | Interventional | Not Applicable | HIV Prevention | 2020-11-26 | 2022-08-01 | University of Washington | No |
| NCT04691609 | EGY |
Dar Al Fouad Hospital; Giza; |
Assiut University Registry for ACS Patients During COVID-19 Pandemic | Observational | ACS-COVID-19-Assiut | 2020-03-01 | 2023-09-01 | Assiut University | Yes | |
| NCT05096559 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
Evaluation of Sublingual Microcirculation in Burn During Resuscitation | Observational | Burn Shock | 2021-02-01 | 2022-02-01 | Cairo University | No | |
| NCT04816851 | EGY |
Assiut University; Assiut; |
Aortic Valve Leaflets Reconstruction (Ozaki Procedure) in Aortic Valve Diseases | Observational | Aortic Valve Disease | 2021-03-30 | 2023-07-30 | Assiut University | No | |
| NCT02265887 | The Pan African Pulmonary Hypertension Cohort Study | Observational | Pulmonary Hypertension | 2012-06-01 | 2015-06-01 | University of Cape Town | No | |||
| NCT05311553 | ZAF |
Netcare Universitas Private Hospital; Bloemfontein; |
Zona Pellucida Thinning Versus Drilling During Laser-assisted Hatching | Interventional | Not Applicable | Infertility | 2020-10-01 | 2022-04-30 | National Research Centre, Egypt | No |
| NCT05204238 | EGY, ZAF, GHA, , BWA, MAR, NGA |
Cardiology Department - Suez Canal University; Ismailia; Cardiology Clinical Research; Alberton; National Cardiothoracic center / Shab Teaching Hospital; Korle-Bu; National Hepatology Institute; Cairo; Cardiology Department - University of Hassan II University; Quartier des Hopitaux; Independence Surgery; Gaborone; Montana Hospital; West Coast; Department of cardiology - University Hospital of Marrakech; Marrakech; Dermatology Department - Ain Shams University; Cairo; Department of Medical Microbiology Parasitology - College of Medicine University of Ibadan; Oyo; Department of Radiation Oncology - University of Cape Town; Cape Town; Tara Hospital; Sandton; Department of Internal Medicine - University of Cape Town; Cape Town; South Valley University; Qena; Netcare Moot General Hospital; Pretoria; Military Hospital; Accra; University Hospital - Tanta University; Tanta; |
Follow Up of acuTe Heart failUre: a pRospective Echocardiographic and Clinical Study (FUTURE) | Observational | Heart Failure,Heart Failure With Reduced Ejection Fraction,Heart Failure With Mid Range Ejection Fraction,Heart Failure With Preserved Ejection Fraction | 2020-09-01 | 2022-11-30 | University of Siena | No | |
| NCT00074581 | ZAF, BWA |
Medicross Medical Centre Parow; Cape Town; Gaborone Clinical Research Site; Gaborone; |
Preventing Sexual Transmission of HIV With Anti-HIV Drugs | Interventional | Phase 3 | HIV Infections | 2005-02-01 | 2015-05-01 | National Institute of Allergy and Infectious Diseases (NIAID) | No |
| NCT04745338 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Effect Of Cryolipolysis On Visceral Adiposity Index In Polycystic Ovarian Syndrome Patients | Interventional | Not Applicable | Polycystic Ovary Syndrome | 2021-03-01 | 2022-02-28 | Cairo University | No |
| NCT04196400 | The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery. | Interventional | Early Phase 1 | Hypospadias | 2019-12-01 | 2021-03-01 | Cairo University | No | ||
| PACTR202201731802989 | Effect of promoting fruits and vegetables consumption on maternal nutritional status and birth weight at Robe and Goba Towns, South East Ethiopia: a cluster randomized controlled trial | RCT | Pregnancy and Childbirth | 2021-01-06 | 1970-01-01 | Jimma University | No | |||
| NCT04553991 | EGY |
Fayoum University Hospital; Fayoum; |
Lateral Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Laparoscopic Surgery | Interventional | Not Applicable | Abdominal Pain | 2019-07-01 | 2020-05-01 | Fayoum University Hospital | No |
| NCT04764773 | TUN |
Abderrahmen Mami Hospital; Tunis; |
Persistence of Symptoms After Improvement of Acute COVID-19 | Observational | Corona Virus Infection | 2020-05-01 | 2021-03-31 | Sohag University | Yes | |
| NCT03443947 | Modified Mallampati Scoring Technique for Airway Assessment | Interventional | Not Applicable | Intubation;Difficult | 2018-03-01 | 2018-12-31 | AlRefaey Kandeel | No | ||
| NCT04707950 | EGY |
Banha University Hospital; Qalyoubia; |
Tranexamic Acid for the Prevention of Postpartum Haemorrhage | Interventional | Phase 1,Phase 2 | Postpartum Hemorrhage | 2020-01-01 | 2021-03-30 | Benha University | No |
| PACTR202103829129395 | TUN |
Hôpital d'enfants; Tunis; |
The effect of soap on communal Handwashing water as a source of faecal contamination during mealtime in households using the same bowl. | RCT | Digestive System,Infections and Infestations,Respiratory | 2021-05-07 | 2021-02-08 | University of Birmingham | No | |
| NCT00067522 | ZMB |
Zambia Emory HIV Research Project; Lusaka; (ZEHRP) |
Preventing Unplanned Pregnancies in HIV Infected Zambian Couples | Interventional | Not Applicable | Pregnancy,HIV Infections | 2002-01-01 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | No | |
| NCT05364398 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
Comparison of ACL Reconstruction With Stump Preservation and Stump Resection | Interventional | Not Applicable | Knee Ligament Injury | 2017-04-01 | 2020-09-01 | Cairo University | No |
| NCT04173819 | Safety and Pharmacokinetics of the Combination Broadly Neutralizing Antibodies, 3BNC117-LS-J and 10-1074-LS-J, in Healthy American and African Adults | Interventional | Phase 1,Phase 2 | HIV-1-infection | 2019-01-25 | 2022-09-01 | International AIDS Vaccine Initiative | No | ||
| NCT01360008 | ZAF |
Netcare Milpark Hospital; Johannesburg; |
FREEZE Cohort Study | Observational | Arrhythmia | 2011-04-01 | 2017-04-01 | Stiftung Institut fuer Herzinfarktforschung | No | |
| NCT04686344 | Egypt, EGY |
Paediatric Hospital - Cairo University; Cairo; NEMROCK Faculty of Medicine - Cairo University; El Azab; |
Point of Care Optic Nerve Sheath Ultrasound to Assess Intracranial Pressure | Interventional | Early Phase 1 | Hypertonic Saline,Optic Nerve Sheath | 2020-12-21 | 2021-08-30 | Cairo University | No |
| NCT04613830 | EGY |
Egypt Air Hospital; Cairo; |
Continuous Erector Spinae Block for Post Analgesia in Pediatric Patients | Interventional | Phase 2,Phase 3 | Pediatric Cancer | 2020-11-20 | 2022-12-30 | Assiut University | No |
| NCT02760888 | EGY |
Ain Shams University; Cairo; |
Oral Tramadol Versus Diclofenac For Pain Relief Before Outpatient Hysteroscopy: | Interventional | Phase 3 | Pain, Procedure | 2016-05-01 | 2016-07-01 | Ain Shams University | No |
| PACTR202003743599701 | ZMB |
Chilenje Level 1 Hospital; Lusaka; |
Partners Scale-Up Project (PSUP) | CCT | Infections and Infestations | 2017-06-02 | 1970-01-01 | University of Washington | No | |
| PACTR201306000510382 | NGA |
Lagos University Teaching Hospital; Idi Araba; |
Transient Neurologic Symptoms following spinal Lignocaine and Bupivacaine for caesarean delivery at Mulago Hospital, a randomised trial. | RCT | its comparing safety profile for the different drugs in the randomised trial.,Nervous System Diseases | 1970-01-01 | 2013-03-05 | Dr Aggrey Lubikire(self) | No | |
| NCT04418310 | Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease | Interventional | Not Applicable | Endoscopic Pilonidal Sinus | 2020-06-12 | 2021-07-01 | Mansoura University | No | ||
| NCT01435018 | South Africa |
University of Witwatersrand; Johannesburg; |
Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS | Interventional | Phase 3 | HIV-1 Infection | 2013-10-01 | 2019-08-29 | AIDS Clinical Trials Group | No |
| NCT04838587 | ZAF |
First Care Medical Centre; Soweto; George Clinical Study Site; George; |
An Epidemiological Surveillance Study to Determine the Incidence of ETEC in Children and Infants in Lusaka | Observational | Diarrhea Toddlers,Escherichia Coli Diarrhea | 2020-10-15 | 2021-10-15 | Centre for Infectious Disease Research in Zambia | No | |
| NCT05238259 | SEN |
El Hadji Ibrahima Niass Hospital; Kaolack; |
Kinesiotaping Versus Wrist Wheel on Upper Extremity Functions in Children With Hemiparetic Cerebral Palsy | Interventional | Not Applicable | Hemiplegic Cerebral Palsy | 2021-12-01 | 2022-03-01 | Cairo University | No |
| NCT03980483 | Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate | Interventional | Phase 3 | Arthritis, Rheumatoid | 2019-05-16 | 2022-08-16 | GlaxoSmithKline | No | ||
| NCT05001035 | Effect of Different Biomimetic Materials on White Spot Lesions in Enamel | Interventional | Not Applicable | White Spot Lesion | 2021-07-01 | 2021-09-20 | Benha University | No | ||
| PACTR202102535686338 | NGA |
Mainland Hospital; Yaba; |
Efficacy of Ivermectin for the Treatment and Prophylaxis of COVID-19 disease | RCT | Infections and Infestations | 1970-01-01 | 1970-01-01 | Lagos State Ministry of Health | Yes | |
| NCT01494987 | ZAF |
Paarl Research Centre; Paarl; Helderberg Clinical Research Centre; Somerset West; Tiervlei Trial Centre; Bellville; (TTC) |
Ranolazine When Added to Glimepiride in Subjects With Type 2 Diabetes Mellitus | Interventional | Phase 3 | Type 2 Diabetes Mellitus | 2012-01-01 | 2013-08-01 | Gilead Sciences | No |
| NCT04964908 | ZAF |
Groote Schuur Clinical Research Site; Cape Town; |
Study to Understand Clinical Characteristics, Treatment Pathway in Chronic Lymphocytic Leukemia | Observational | Chronic Lymphocytic Leukemia | 2021-12-03 | 2022-11-15 | AstraZeneca | No | |
| NCT04684680 | EGY |
Aswan Heart Center; Aswan; |
The Role of Zamzam Water in Idiopathic Oligohydramnios | Interventional | Not Applicable | Oligohydramnios | 2021-01-01 | 2021-11-01 | Aswan University Hospital | No |
| NCT02007005 | Maximum Tolerable Concentration of abnobaVISCUM Fraxini Intravesically in Patients With Superficial Bladder Cancer | Interventional | Phase 1,Phase 2 | Superficial Bladder Cancer | 2004-01-01 | 2013-09-01 | Abnoba Gmbh | No | ||
| NCT05311111 | TUN |
The Military hospital of Tunis; Tunis; |
Efficacy and Safety of the Distal Radial Approach | Interventional | Not Applicable | Coronary Artery Disease,Vascular Access Complication | 2022-02-01 | 2022-06-30 | General Administration of Military Health, Tunisia | No |
| NCT04141449 | A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation | Interventional | Phase 2 | Hiv,HNSCC,Neoplasms,Anal Cancer,Breast Cancer,Vulvar Cancer,Cancer Suspect,Cervical Cancer | 2020-11-18 | 2024-09-19 | Brigham and Women's Hospital | No | ||
| NCT05338723 | EGY |
University Hospital - Tanta University; Tanta; |
Possible Protective Effect of Rosuvastatin in Chemotherapy-induced Cardiotoxicity in HER2 Positive Breast Cancer Patients | Interventional | Phase 3 | Breast Cancer,Chemotherapy-induced Cardiotoxicity | 2020-09-15 | 2023-09-15 | Tanta University | No |
| NCT05533424 | TUN |
Abderrahmen Mami Hospital; Tunis; |
Ultrasound Guided Quadratus Lumborum Block Versus Transversus Abdominis Plane Block as Postoperative Analgesia in Patients Undergoing Abdominal Cancer Surgery. | Interventional | Phase 3 | Abdominal Cancer | 2022-09-01 | 2023-12-15 | Mansoura University | No |
| NCT04862975 | BWA |
Botswana - University of Pennsylvania; Gaborone; (Upenn) |
Pharmacokinetic and Safety of Antiretroviral and Related Drugs in Lactating Women and Breastmilk Fed Infants | Observational | HIV Infections,Lactating Women on Select DOI,Breastmilk Fed Infants of Mothers on Select DOI | 2023-01-01 | 2024-05-24 | Duke University | No | |
| PACTR201906531856469 | ETH |
Hawassa University Referral Hospital; Awassa; |
Comparison of Thoracic Paravertebral Block and Transversus Abdominis Plane Block for Postoperative Analgesisa in Major Gynecologic Surgery: Randomized Controlled Clinical Trial, Dilla University Referral Hospital, Dilla Town, South Ethiopia; 2018 | RCT | Anaesthesia,Obstetrics and Gynecology | 2018-01-07 | 1970-01-01 | Dilla University | No | |
| NCT04663711 | EGY |
Faculty of Medicine - Minia University; El Menia; |
The Degree of Adherence of Pre-anesthetic Tests at Kasr Alaini Hospital to the NICE-Uk Guidelines | Observational | Anesthesia | 2020-09-10 | 2021-08-10 | Cairo University | No | |
| PACTR201808158196289 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
EFFECTS OF VESTIBULAR REHABILITATION ON POSTURAL STABILITY IN ANTERIOR CIRCULATION STROKE PATIENTS: A RANDOMIZED CONTROLLED TRIAL | RCT | Circulatory System,Nervous System Diseases | 2019-02-03 | 2020-02-03 | faculty of physicl therapy cairo university | No | |
| PACTR201805003296247 | NGA |
Lagos University Teaching Hospital; Idi Araba; |
Posterior root canal treatment outcome and antibacterial efficacy using conventional irrigation versus combined with passive ultrasonic irrigation | RCT | Irreversible pulpitis, apical periodontitis,Oral Health | 2017-03-05 | 2018-05-12 | Adedayo Oreoluwa Lawal | No | |
| NCT05486429 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Evaluation of Lipid Profile in Different Grades of Non-alcoholic Fatty Liver Disease Diagnosed by Ultrasound | Observational | Non-Alcoholic Fatty Liver Disease | 2022-07-20 | 2023-01-20 | Sohag University | No | |
| NCT05240846 | EGY |
Faculty of Medicine - Kafr El-sheikh University; Kafr el-Sheikh; |
Spinal Anesthesia Using Ultrasound Assistance Versus Conventional Palpation in Morbidly Obese Patients | Interventional | Not Applicable | Obesity, Morbid,Spinal Anesthesia,Ultrasound Assistance | 2022-02-23 | 2022-09-20 | Kafrelsheikh University | No |
| PACTR201611001473594 | Kenya |
The Aga Khan University Hospital; Nairobi; |
Comparison of Weight Adjusted Dose versus Fixed Dose Ondansetron in Preventing Shivering Following Spinal Anesthesia for Cesarean Deliveries | RCT | Pregnancy and Childbirth,shivering post spinal anesthesia in women undergoing cesarean section | 2015-10-08 | 1970-01-01 | AGA KHAN UNIVERSITY NAIROBI | No | |
| NCT05050695 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Correlation Between Posterior Oblique Sling Activation and Contralateral Glenohumeral Stability in Low Back Pain | Observational | Chronic Low-back Pain | 2021-10-04 | 2022-01-25 | Shaimaa Ramadan Ibrahim Abdul-ghani El Deab | No | |
| NCT03772665 | ZAF |
Pretoria Eye Institute; Pretoria; |
Safety and Efficacy of Emixustat in Stargardt Disease | Interventional | Phase 3 | Stargardt Disease | 2018-11-07 | 2022-06-23 | Kubota Vision Inc. | No |
| PACTR201810624534118 | EGY |
Poison Control Center - Tanta University; Tanta; |
Albuterol as an Adjuvant Therapy in Acute Anticholinesterase Pesticides Poisoning: A Randomized Clinical Trial | RCT | Injury, Occupational Diseases, Poisoning | 2017-01-05 | 1970-01-01 | Tanta university | No | |
| PACTR202004658330781 | SINGLE DOSE VERSUS MULTIPLE DOSES ANTIBIOTIC PROPHYLAXIS IN CAESAREAN SECTION: A RANDOMIZED CONTROL TRIAL | RCT | Obstetrics and Gynecology | 1970-01-01 | 1970-01-01 | Gerald Igwemadu | No | |||
| NCT05522712 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Acapella Versus Incentive Spirometer on Cardiopulmonary Fitness After Heart Valve Surgery. | Interventional | Not Applicable | Heart Diseases,Open Heart Surgery,Heart Valve Diseases | 2022-01-01 | 2023-03-30 | Cairo University | No |
| NCT00380393 | Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children. | Interventional | Phase 2 | Malaria | 2007-01-03 | 2008-11-11 | GlaxoSmithKline | No | ||
| NCT04618146 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine. | Interventional | Not Applicable | Pruritus,Pain, Postoperative,Nausea, Postoperative,Vomiting, Postoperative | 2020-11-10 | 2021-03-01 | Minia University | No |
| NCT00403962 | A Combination Therapy In Patients With Social Anxiety Disorder | Interventional | Phase 2 | Social Phobia | 2004-11-01 | 2005-08-01 | GlaxoSmithKline | No | ||
| NCT01955382 | MLI |
University of Science Techniques and Technologies of Bamako; Bamako; (USTTB) |
Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria | Interventional | Phase 2 | Malaria,Severe Malaria | 2013-09-01 | 2015-07-01 | National Institute of Allergy and Infectious Diseases (NIAID) | No |
| NCT03890705 | EGY |
Assiut University; Assiut; |
Postpartum Family Planning Utilization and Associated Factors Among Women During First Year After Childbirth in Assiut | Observational | Contraception | 2019-06-01 | 2020-06-01 | Assiut University | No | |
| PACTR202004705649428 | South Africa |
Africa Health Research Institute; Durban; (AHRI) |
BabyGel Trial | RCT | Infections and Infestations,Neonatal Diseases,Paediatrics,Pregnancy and Childbirth | 2020-04-05 | 2022-04-09 | University of Liverpool | No | |
| NCT00673842 | ZAF |
Netcare Unitas Hospital; Centurion; Honeydew Medical Centre; Roodepoort; |
Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction | Interventional | Phase 3 | Sudden Death,Myocardial Infarction | 2011-03-01 | 2021-12-01 | University of Calgary | No |
| NCT03450798 | EGY |
Ain Shams University; Cairo; |
SOFT Block Versus Spinal Anesthesia in Patientsusing Ilizarov External Fixator | Interventional | Not Applicable | Pain, Acute | 2018-02-10 | 2019-01-10 | Ain Shams University | No |
| PACTR201901837047199 | KEN |
Family AIDS Care and Education Services; Kisumu; (FACES) |
Revealing a safe sex option to reduce HIV risk: a cluster-randomized trial in Botswana. | RCT | Infections and Infestations,Pregnancy and Childbirth | 1970-01-01 | 2015-01-12 | Young 1ove | No | |
| NCT00386763 | Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria. | Interventional | Phase 3 | Malaria,Falciparum | 2006-08-01 | 2007-03-01 | Novartis | No | ||
| NCT03501524 | EGY |
Assiut University; Assiut; |
VATS Evacuation Compared to Reinsertion of Thoracostomy Tube in Persistent Traumatic Haemothorax | Interventional | Not Applicable | Hemothorax; Traumatic | 2017-07-01 | 2018-07-30 | Assiut University | No |
| NCT04860284 | EGY |
Nasser Institute for Research and Treatment; Cairo; |
Hydroxychloroquine for Treatment of Non-Severe COVID-19 | Interventional | Phase 2 | Covid19 | 2020-09-18 | 2021-12-01 | Makerere University | Yes |
| PACTR202206919034739 | EGY |
Dermatology Department - Ain Shams University; Cairo; |
Short-term Outcomes of Reduced versus Conventional Ports in Sleeve Gastrectomy: A Controlled Clinical Trial | CCT | Digestive System,Morbid Obesity,Surgery | 2022-01-07 | 1970-01-01 | Department of Surgery Ain shams university | No | |
| PACTR201810756862405 | ZAF |
Wits RHI Shandukani Research Centre CRS; Johannesburg; (RHI) |
Operations research to estimate the effectiveness of a peer-led mental health intervention on virological suppression and mental health among adolescents with HIV in Zimbabwe | RCT | Infections and Infestations,Mental and Behavioural Disorders | 2018-01-11 | 1970-01-01 | Africaid | No | |
| NCT05283668 | EGY |
Ain Shams University; Cairo; |
Effect of Injectable Platelet Rich Fibrin on Healing and Patient Satisfaction Following Laser Gingival Depigmentation | Interventional | Phase 4 | Gingival Pigmentation | 2020-02-20 | 2022-01-30 | Ain Shams University | No |
| PACTR201507000984471 | EGY |
Cancer Center - Menoufiya University; Menoufiya; |
Cardiac and renal protective effects of dexmedetomidine in cardiac surgeries | RCT | Cardiac and renal protective,Circulatory System | 2012-11-06 | 2014-07-01 | Minoufiya university | No | |
| NCT03777358 | EGY |
Mansoura University Hospitals; Mansoura; |
Three-dimensional Ultrasonography Versus Hysteroscopy in Evaluation of Uterine Cavity in Infertile Women | Observational | Female Infertility | 2019-01-01 | 2021-01-01 | Hatem AbuHashim | No | |
| NCT05746819 | MWI, Zambia |
Queen Elizabeth Central Hospital - Malawi-Liverpool Wellcome Trust Research Programme; Blantyre; (QECH) Chipata Central Hospital; Chipata; |
An MRI Ancillary Study of a Malaria Fever Investigation (MRIA) | 2021-01-02 | 2023-08-30 | University of Rochester | No | |||
| NCT03338218 | ZAF, TUN, TZA, NGA, Uganda, EGY, SEN, MOZ, DZA, KEN, CMR, GHA |
Clinteam Vaal Clinical Trial Centre; Vanderbijlpark; Paarl Research Centre; Paarl; Clinical Projects Research; Worcester; Department of Anesthesia and Intensive Care - Fattouma Bourguiba Hospital; Monastir; Steve Biko Academic Hospital - University of Pretoria; Pretoria; Department of Clinical and Laboratory Research - National Institute for Medical Research; Dodoma; Global Clinical Trials; Pretoria; Centre for Malaria Research and Phytomedicine - University of Port Harcourt; Port Harcourt; Universitas Academic Hospital; Bloemfontein; Rustenburg CRS; Rustenburg; Kabwohe Clinical Research Centre; Kabwohe; NEMROCK Faculty of Medicine - Cairo University; El Azab; Hôpital de Fann; Dakar; Consultorio Medico Esperanza; Chimoio; Centre Hospitalo universitaire Bologhine Hospital; Algiers; Central Primary Health Centre; Akahia; Bondo Clinic - Bondo District Hospital; Bondo; Universitas Hospital; Bloemfontein; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; Hiway Medical Center; Durban; NESTRA KLINIkAL; Ibadan; Limbe Health Center; Sud-Ouest; Military Hospital; Accra; |
Safety and Efficacy of a 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Trauma Patients | Interventional | Phase 4 | Hypovolemia Due to Acute Blood Loss | 2019-02-23 | 2022-06-25 | Fresenius Kabi | No |
| NCT05114122 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Clinical Outcomes of Premolars Restored With Ceramic Vonlay Restorations Versus Onlay Using Modified USPHS Criteria | Interventional | Not Applicable | Clinical Performance of Ceramic Vonlays | 2021-01-01 | 2022-01-01 | Cairo University | No |
| NCT05522114 | Egypt |
Al-Azhar University; Cairo; |
Accuracy of Patient Specific Guide for TMJ Injection | Interventional | Not Applicable | TMD | 2022-04-19 | 2022-08-22 | Al-Azhar University | No |
| NCT04775225 | EGY |
ElManial ElGamaei Specialized Hospital; Cairo; |
Hip Denervation in Juvenile Idiopathic Arthritis With Hip Arthritis | Interventional | Phase 3 | Hip Arthritis,Juvenile Idiopathic Arthritis | 2021-01-06 | 2021-04-06 | Sohag University | No |
| NCT03337724 | ZAF |
The Oncology Centre - Onco Care Specialist Oncologists; Durban; |
A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer | Interventional | Phase 2,Phase 3 | Breast Cancer | 2018-01-06 | 2022-12-22 | Hoffmann-La Roche | No |
| NCT04698070 | UGA, SDN, EGY, Sudan |
Kasangati Health Center IV; Wakiso; Institute of Endemic Diseases - Kassab Hospital; El Gadarif; The Cairo Kidney Center; Cairo; University of Khartoum; Khartoum; |
Optimizing Acute Malnutrition Management in Children Aged 6 to 59 Months in Niger (OptIMA Niger) | Interventional | Not Applicable | Acute Malnutrition in Infancy (Disorder) | 2021-03-22 | 2022-06-24 | Alliance for International Medical Action | No |
| NCT05209009 | UGA |
Uganda Virus Research Institute; Entebbe; |
A Clinical Trial of COVAC-2 in Adults | Interventional | Phase 2 | Severe Acute Respiratory Syndrome Coronavirus 2 | 2022-08-24 | 2023-08-01 | University of Saskatchewan | No |
| NCT05132023 | Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany) | Interventional | Phase 1 | Healthy | 2019-03-26 | 2019-05-15 | Genuine Research Center, Egypt | No | ||
| NCT05395585 | EGY |
Ain Shams University; Cairo; |
The Effect of Placental Spontaneous Delivery Versus Manual Removal on Blood Loss During Cesarean Section. A Comparative Study | Interventional | Not Applicable | Cesarean Section Complications | 2022-06-01 | 2023-01-01 | Ain Shams University | No |
| NCT04690894 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Erector Spinae Muscle Block Versus Caudal Block by Sonar in Pediatrics Undergoing Lower Abdominal Surgery | Interventional | Not Applicable | Postoperative Analgesia | 2019-07-15 | 2020-02-15 | Minia University | No |
| NCT01540903 | Tanzania |
Bagamoyo Research and Training Center; Bagamoyo; (BRTC) Ifakara Health Institute; Bagamoyo; (IHI) |
Controlled Human Malaria Infection by Intradermal Injection of Plasmodium Falciparum Sporozoites in Tanzanian Adults | Interventional | Phase 1 | Malaria | 2012-02-01 | 2013-08-01 | Sanaria Inc. | No |
| PACTR202104554144365 | ZAF |
Neurology Department - Groote Schuur Hospital; Cape Town; |
Does hair curl variation influence the efficacy of scalp cooling in the prevention of chemotherapy-induced alopecia in breast cancer patients? A randomised pilot trial | RCT | Cancer,Skin and Connective Tissue Diseases | 1970-01-01 | 1970-01-01 | Nonhlanhla P Khumalo | No | |
| NCT05488561 | Egypt, TUN |
Sohag University Hospital; Sohag; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Clinical and Molecular Evaluation of Childern With Familial Meditterranean Fever and Their Siblings | Interventional | Not Applicable | Familial Mediterranean Fever | 2022-08-15 | 2023-08-01 | Sohag University | No |
| NCT02293460 | TUN |
Hopital Militaire; Tunis; |
Efficacy and Safety Study of I10E in Treatment of Patients With CIDP | Interventional | Phase 3 | Chronic Inflammatory Demyelinating Polyradiculoneuropathy | 2015-05-01 | 2017-09-29 | Laboratoire français de Fractionnement et de Biotechnologies | No |
| NCT04372693 | Unplanned Shifting to Online Distance Learning: Nursing Students' Perception and Achievement | Interventional | Not Applicable | Distance Learning-Online Learning,Traditional Classroom-Based Learning,Nursing Students' Perception and Achievement,Coronavirus Disease Social Distancing Measures | 2020-09-01 | 2021-07-31 | Kasr El Aini Hospital | No | ||
| PACTR201902720180705 | Egypt |
Al-Azhar University; Cairo; |
Effect of buffered dextrose on pain occurring during local steroid injection for plantar fasciitis | RCT | Musculoskeletal Diseases | 2018-01-10 | 2019-01-02 | Abdelhafeez Moshrif | No | |
| NCT05310916 | EGY |
Dermatology Department - Ain Shams University; Cairo; |
Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients | Interventional | Phase 3 | Diabetic Retinopathy | 2022-06-06 | 2023-11-01 | Nidae Alaa | No |
| NCT04708353 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Oral Pregabalin Premedication for Postoperative Pain Relief | Interventional | Not Applicable | Gynecologic Disease | 2020-08-20 | 2021-11-01 | Zagazig University | No |
| NCT02531529 | Dexmedetomedine Infusion Versus Fentanyl Infusion for Donor Anlgesia During Living Donor Hepatectomy | Interventional | Not Applicable | Donor Hepatectomy | 2014-01-01 | 2015-04-01 | Mansoura University | No | ||
| NCT04000009 | ZAF |
Scion Clinical Research; Pretoria; |
Extension Study of Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment | Interventional | Phase 3 | Adjunctive Treatment of Major Depressive Disorder | 2019-06-06 | 2021-02-22 | ACADIA Pharmaceuticals Inc. | No |
| NCT03864419 | ZAF |
Hopelands Cancer Centre; Durban; |
Rituximab Hyaluronidase in Combination With Chemotherapy in Treating Aggressive B-cell Lymphoma in Uganda | Interventional | Phase 1 | Burkitt Lymphoma,Diffuse Large B-Cell Lymphoma,KSHV-associated Multicentric Castleman Disease | 2019-10-24 | 2023-12-31 | Fred Hutchinson Cancer Research Center | No |
| NCT01001741 | BWA |
Independence Surgery; Gaborone; |
Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana | Interventional | Not Applicable | HIV Infections | 2008-06-01 | 2009-08-01 | University of Pennsylvania | No |
| NCT05042895 | EGY |
University Hospital - Tanta University; Tanta; |
Hysteroscopic Findings in Ovarian Polycystic and Unexplained Infertile Women. | Interventional | Not Applicable | Infertility | 2021-08-20 | 2022-12-02 | Woman's Health University Hospital, Egypt | No |
| NCT04546230 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy. | Interventional | Not Applicable | Epidural,Anesthesia,Nephrectomy,Laparoscopic | 2020-09-19 | 2023-01-01 | Nazmy Edward Seif | No |
| NCT03944317 | NGA |
Federal Medical Center; Owo; (FMCOWO) |
Azithromycin (AZ) and Sulphadoxine-pyrimethamine (SP) for Malaria Prevention in Pregnant Women (IPT-AZ/IPT-SP) | Interventional | Not Applicable | Pregnancy,Malaria in Pregnancy | 2019-06-01 | 2020-01-31 | Federal Medical Centre, Owo | No |
| NCT00509015 | TZA |
Kilimanjaro Christian Medical Centre; Moshi; (KCMC) |
Mass-Drug Administration to Reduce Malaria Transmission | Interventional | Not Applicable | Malaria, Falciparum | 2008-02-01 | 2008-08-01 | Radboud University | No |
| NCT05154903 | EGY |
Ain Shams University; Cairo; |
Citicoline in Ischemic Stroke | Interventional | Phase 3 | Acute Ischemic Stroke | 2021-07-22 | 2022-06-22 | Ain Shams University | No |
| NCT04981964 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Altered Back Geometry and Mobility Function After Backward Walking Training in Children With Cerebral Palsy | Interventional | Not Applicable | Cerebral Palsy, Spastic | 2021-08-01 | 2021-10-30 | Cairo University | No |
| PACTR201503001057193 | ZAF |
Endocare Research; Cape Town; |
Ebola Vaccine Ring Vaccination Trial in Guinea | RCT | Ebola Virus Disease | 2015-07-03 | 1970-01-01 | World Health Organization | No | |
| NCT05076773 | EGY |
Faculty of Medicine - Minia University; El Menia; |
TPVB, PECSB, ESPB for Postmastectmy Pain | Interventional | Not Applicable | Pain, Postoperative | 2019-04-10 | 2021-08-10 | Menoufia University | No |
| NCT05199727 | EGY |
Menoufia University Hospital; Menoufia; |
Shock Wave vs. On-demand Tadalafil for Erectile Dysfunction | Interventional | Not Applicable | Erectile Dysfunction | 2021-09-01 | 2022-05-01 | Menoufia University | No |
| NCT04769102 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Seat Cushions Adaptations on Upper Extremity Function In Cerebral Palsy Children | Interventional | Not Applicable | Cerebral Palsy | 2021-02-01 | 2022-08-30 | Cairo University | No |
| NCT03997019 | Erector Spinae Plane Block in Cardiac Surgery | Interventional | Not Applicable | Pain, Acute | 2019-02-15 | 2020-12-15 | Assiut University | No | ||
| NCT05391230 | Uganda |
Mbarara University of Science and Technology; Mbarara; (MUST) |
Permethrin-treated Baby-wraps for the Prevention of Malaria in Children | Interventional | Not Applicable | Malaria,P. Falciparum | 2022-06-03 | 2025-06-01 | University of North Carolina, Chapel Hill | No |
| PACTR201301000452148 | ZAF |
Limpopo Clinical Research Initiative; Limpompo; |
Lifestyle intervention to control high normal blood pressure and/or high normal blood glucose in church members | RCT | high normal blood pressure and/or high normal blood glucose,Nutritional, Metabolic, Endocrine | 2012-01-02 | 2017-05-01 | VLIR | No | |
| NCT04426032 | EGY |
Ain Shams University; Cairo; |
Predictive Value of Doppler RSI for Prediction of AKI in Septic Patients in ICU | Observational | Sepsis,Acute Kidney Injury | 2020-07-01 | 2021-01-31 | Ain Shams University | No | |
| NCT03273348 | EGY |
Assiut University; Assiut; |
Role of Oncoplastic Breast Surgery In Breast Cancer Treatement | Interventional | Not Applicable | Breast Cancer | 2017-09-28 | 2019-10-28 | Assiut University | No |
| NCT02414308 | ZAF |
Mamma Clinic; Cape Town; |
Management of Peyronie's Disease With Adipose Tissue Stem Cell | Interventional | Not Applicable | Peyronie' Disease,Erectile Dysfunction | 2013-06-01 | 2016-07-01 | Man Clinic for Andrology, Male Infertility and Sexual Dysfunction | No |
| NCT04324463 | EGY, KEN, ZAF, DZA, Uganda, SEN, SLE, COD, MOZ, GHA, Egypt, RWA, NGA, TUN, Kenya, BEN, CMR |
Sadmawy Hospital - Zagazig University; Zagzig; Family AIDS Care and Education Services; Kisumu; (FACES) Dar El Oyoun Hospital; Giza; Life Entabeni Hospital; Berea; Kenyatta National Hospital; Nairobi; (KNH) City Park Medical Centre; Cape Town; Netcare Unitas Hospital; Centurion; Centre Hospitalier Universitaire Sidi Bel abbas; Sidi Bel Abbès; (CHU) National Hepatology Institute; Cairo; Mbale Regional Referral Hospital; Mbale; Niakhar Demographic Surveillance System; Dakar;(DS IDR) Western Cape Clinical Trials; Western Cape; College of Medicine and Allied Health Sciences - London School of Hygiene &Tropical Medicine; Kambia; (COMAHS - LSHTM) Vista Clinic; Centurion; Centre Hospitalier du Mont-Amba; Kinshasa; Polana Caniço Health Research and Training Center - Instituto Nacional de Saúde and Ministry of Health; Cidade de Maputo; (CISPOC) Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region; Biomedical Research Center; Senegal; (EPLS) Oude Westhof Medical Centre; Bellville; Medicor Centre; Kempton Park; Graduate School Of Health Sciences - Kenya Medical Research Institute; Nairobi; (KGHS-KEMRI) Consultorio Medico Esperanza; Chimoio; Health Insurance Hospital; Beni Suef; College of Medicine and Health Sciences; Gasabo; National Heart Institute; Giza; Kenyatta University Teaching Referral and Research Hospital; Kahawa West; Fayoum University Hospital; Fayoum; Clinique Dermatologique; Dakar; Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH) Central Primary Health Centre; Akahia; Bondo Clinic - Bondo District Hospital; Bondo; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; Centre Hospitalo-Universitaire de Constantine; Constantine; (CHU) The Aga Khan University Hospital; Nairobi; Clinical Research Center - Muelmed Hospital; Pretoria; Kimberley Hospital Complex; Kimberley; Centre de Diagnostic et de Traitement de la Tuberculose de Matéri; Matéri; Netcare Moot General Hospital; Pretoria; Mathare North City Clinic; Nairobi; Netcare Milpark Hospital; Johannesburg; District Health De Foumban; Foumban; |
Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial | Interventional | Phase 3 | Coronavirus,Severe Acute Respiratory Syndrome | 2020-04-21 | 2022-10-01 | Population Health Research Institute | Yes |
| PACTR202105818874512 | ETH |
Ethiopian Public Health Association; Addis Ababa; |
A study to assess the effect of a text message intervention using mobile phones to promote clinical antenatal uptake and institutional deliveries among young expectant women in Kwale County, Kenya. | CCT | Pregnancy and Childbirth | 2020-01-10 | 1970-01-01 | World Health Organization HRP Alliance for Research Capacity Strengthening | No | |
| NCT04884022 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Effectiveness of Two Skeletally Anchored Force Mechanics for Skeletal Class II Correction in Growing Patients | Interventional | Not Applicable | Malocclusion | 2021-03-08 | 2022-12-01 | Alexandria University | No |
| NCT04677075 | EGY |
Faculty of Medicine - Minia University; El Menia; |
New Formula to Predict the Need for Reconstructive Coverage Following Mastectomy | Observational | Breast Neoplasms | 2020-08-15 | 2020-11-15 | Zagazig University | No | |
| NCT04703608 | Uganda |
MRC/UVRI & LSHTM Uganda Research Unit; Entebbe; |
Prevention and Treatment for COVID -19 (Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2) Associated Severe Pneumonia in the Gambia | Interventional | Phase 3 | Covid-19 | 2021-01-22 | 2022-07-01 | London School of Hygiene and Tropical Medicine | Yes |
| PACTR201805003376209 | ZAF |
Family Clinical Research Unit - Tygerberg Hospital; Tygerberg; (FAM-CRU CRS) |
Outcome of intra-medullary nailing compared to conventional plating in middle third clavicle fractures - a prospective randomized controlled trial | RCT | Injury, Occupational Diseases, Poisoning,Musculoskeletal Diseases,Patients with clavicle fractures | 2011-07-07 | 1970-01-01 | South Africa Orthopaedic Association - for reimbursement of travel cost of patients | No | |
| NCT01053325 | Zambia |
Kabuta Rural Health Centre; Nchelenge; |
Establishing Effectiveness of Daily Co-trimoxazole Prophylaxis For Prevention of Malaria in Pregnancy | Interventional | Phase 3 | HIV Infections,Malaria in Pregnancy | 2010-09-01 | 2013-02-01 | Institute of Tropical Medicine, Belgium | No |
| NCT04336085 | ZAF |
Tara Hospital; Sandton; |
Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery | Interventional | Not Applicable | Post Operative Pain After Pediatric Hip Surgery | 2020-05-15 | 2021-05-31 | Tanta University | No |
| NCT04709133 | EGY |
Assiut University; Assiut; |
Clinical Outcomes Of Multi-ligament Knee Injuries In Assiut University Hospitals | Interventional | Not Applicable | Knee Injuries | 2021-01-01 | 2023-12-01 | Assiut University | No |
| NCT03027258 | NGA |
Catholic Caritas Foundation; Abuja; |
Point-of-Delivery Prenatal Test Results Through mHealth to Improve Birth Outcome | Interventional | Not Applicable | HIV,Hepatitis B,Sickle Cell Disease | 2016-09-01 | 2018-01-01 | University of Nevada, Las Vegas | No |
| NCT04773990 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Efficacy of Balance Training by BBS on Gait Parameters and Balance in Patients With Recurrent Lateral Ankle Sprain | Interventional | Not Applicable | Ankle Sprains | 2020-10-01 | 2021-02-15 | MTI University | No |
| NCT04711538 | BWA |
University of Botswana/McMAsters University; Gaborone; |
Role of Diagnostic Imaging in Cochlear Implant | Observational | Cochlear Implant | 2021-02-01 | 2022-10-01 | Sohag University | No | |
| NCT04479280 | EGY |
Assiut University; Assiut; |
Evaluation of Coagulopathy in Critically Ill COVID-19 Patients. | Observational | Coagulation Disorder | 2020-07-20 | 2020-08-16 | Assiut University | Yes | |
| NCT05221749 | The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth | Interventional | Phase 3 | Caries,Primary Teeth,Microbial Colonization,Dental Caries in Children | 2022-03-15 | 2022-06-15 | Nour Ammar | No | ||
| NCT05422118 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Ascitic Fluid Calprotectin as an Accurate Diagnostic Marker for Spontaneous Bacterial Peritonitis | Interventional | Not Applicable | Spontaneous Bacterial Peritonitis | 2022-06-10 | 2022-12-01 | Sohag University | No |
| NCT00002914 | Piritrexim in Treating Patients With Advanced Cancer of the Urinary Tract | Interventional | Phase 2 | Bladder Cancer,Urethral Cancer,Transitional Cell Cancer of the Renal Pelvis and Ureter | 1997-05-01 | 2004-03-01 | Eastern Cooperative Oncology Group | No | ||
| NCT02281526 | ZAF |
FARMOVS Integrated Research Solutions; Bloemfontein; |
An Open-label, Multiple-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093 | Interventional | Phase 1 | Epilepsy | 2005-05-01 | 2006-02-01 | Bial - Portela C S.A. | No |
| NCT02497989 | KEN |
Impact Research and Development Organization; Kisumu; (IRDO) |
Evaluating Demand Creation Strategies for Voluntary Medical Male Circumcision (VMMC) in Kenya | Interventional | Not Applicable | HIV/AIDS | 2015-02-01 | 2016-01-22 | Impact Research & Development Organization | No |
| NCT05071690 | TUN |
Eshmoun Clinical Research Centre; Tunis; |
Observational Study of Infants Fed on DHA (Breast Source or Milk Formula Source ) and Its Effects on Covid-19 Infected Infants and Severity | Observational | DHA as Antioxidant Anti-inflammatory Immunomodulation , Overcome Cytokine Storm | 2021-11-01 | 2022-01-01 | Ministry of Health, Saudi Arabia | Yes | |
| NCT04102293 | EGY |
Ain Shams University; Cairo; |
"Clinical and CBCT Evaluation of the Quality of Obturation and Time Efficiency of Rotary Versus Manual Instrumentation in Pediatric Endodontics" | Interventional | Not Applicable | Endodontic Disease | 2019-09-01 | 2022-01-01 | Reem Mahmoud Abdelkader Awad | No |
| NCT03253315 | EGY |
Assiut University; Assiut; |
Management of Pericarditis in Children. | Observational | Pericarditis | 2017-09-01 | 2019-04-01 | Assiut University | No | |
| NCT00317122 | Assess the Immune Response Following Primary Vaccination With GSK Biologicals' Tritanrix™-HepB/Hib-MenAC vs Tritanrix™-HepB/Hiberix™ Given at 6,10 & 14 Wks of Age to Infants Who Received Hepatitis B Vaccine at Birth | Interventional | Phase 3 | Diphtheria; Haemophilus Influenzae Type b; Hepatitis B; Tetanus; Whole Cell Pertussis | 2004-10-01 | 2005-07-01 | GlaxoSmithKline | No | ||
| NCT00004179 | ZAF |
Mary Potter Oncology Centre; Pretoria; |
Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma | Interventional | Phase 3 | Lymphoma | 1999-05-01 | 2017-07-19 | European Organisation for Research and Treatment of Cancer - EORTC | No |
| PACTR202005538858076 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
EFFICACY OF MEDITERRANEAN DIET ON MUSCLE PERFORMANCE IN PATIENTS WITH RHEUMATOID ARTHRITIS: A RANDOMIZED CONTROLLED TRIAL. | RCT | Musculoskeletal Diseases | 1970-01-01 | 1970-01-01 | cairo university | No | |
| NCT00838903 | Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes | Interventional | Phase 3 | Diabetes Mellitus, Type 2 | 2009-02-01 | 2013-04-01 | GlaxoSmithKline | No | ||
| NCT04745351 | ZAF, ZWE, South Africa, SDN, SEN, EGY, ETH, MOZ, NGA, MAR, MWI, KEN, TUN, CMR, Ghana, LBR |
Clintrial Consultants; Cape Town; Luveve Clinic; Bulawayo; Cape Trial Centre; Bellville; Netcare Unitas Hospital; Centurion; Manor Medical Center; Sandton; Department of Radiotherapy - Addington Hospital; Durban; King DiniZulu Hospital Complex; Durban; Institute of Endemic Diseases - Kassab Hospital; El Gadarif; Arthritis Clinical Research Trials; Cape Town; Africa Health Research Institute; Durban; (AHRI) Niakhar Demographic Surveillance System; Dakar;(DS IDR) Western Cape Clinical Trials; Western Cape; Life Flora Clinic; Roodepoort; Southern Cross Hospital; Cape Town; Medigate Medical Centre; Umhlanga; Cairo University Hospital; Cairo; Deborah Retief Memorial Hospital; Mochudi; Hawassa University Referral Hospital; Awassa; Polana Caniço Health Research and Training Center - Instituto Nacional de Saúde and Ministry of Health; Cidade de Maputo; (CISPOC) Immanuel General Hospital; Eket; Faculty of Health Sciences - University of Cape Town; Cape Town; (UCT) Department of cardiology - Military hospital Marrakech; Marrakech; George Clinical Study Site; George; University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC) Pretoria Heart Hospital; Pretoria; St. James's Hospital Life Health; East London; Bondo Clinic - Bondo District Hospital; Bondo; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; Care and Health Program; Yaounde; Noguchi Memorial Institute for Medical Research; Accra; (NMIMR) Menoufia University Hospital; Menoufia; Ethiopian Public Health Association; Addis Ababa; Kimberley Hospital Complex; Kimberley; Ladywell Medical Centre West; Durban; Emery Clinical Services; Alberton; Intercare Medical and Dental Centre; Lynwood; Urology and Nephrology Centre - Mansoura University Hospitals; El Bostan; Netcare Moot General Hospital; Pretoria; ELWA Medical Center; Monrovia; Merlot House; Cape Town; University Hospital - Tanta University; Tanta; |
Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19) | Interventional | Phase 3 | COVID-19 | 2021-03-31 | 2022-05-24 | Gilead Sciences | Yes |
| NCT05146635 | EGY |
Urology and Nephrology Centre - Mansoura University Hospitals; El Bostan; |
Optimal Adjuvant Intravesical Therapy for Intermediate Risk Non Muscle Invasive Bladder Cancer: A Randomized Controlled Trial | Interventional | Not Applicable | Bladder Cancer | 2021-12-01 | 2023-01-01 | Mansoura University | No |
| NCT04941053 | EGY |
University Hospital - Tanta University; Tanta; |
Seroprevalence of COVID-19 | Observational | Covid19 | 2021-06-03 | 2021-09-30 | Sohag University | Yes | |
| PACTR202103587471967 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
Effect of dual task on balance of multiple sclerosis patients | RCT | Nervous System Diseases | 2020-01-09 | 1970-01-01 | self | No | |
| PACTR202008842095447 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Integrated neuromuscular inhibition for neck pain | RCT | Musculoskeletal Diseases,Orthopaedics | 2020-04-08 | 2020-04-10 | aliaa elabd | No | |
| NCT00217737 | ZAF, KEN |
RK Khan Hospital; Chatsworth; Netcare Unitas Hospital; Centurion; Kisumu County Hospital; Kisumu; Universitas Hospital; Bloemfontein; |
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer | Interventional | Phase 3 | Lynch Syndrome,Colon Mucinous Adenocarcinoma,Stage IIA Colon Cancer AJCC v7,Stage IIB Colon Cancer AJCC v7,Stage IIC Colon Cancer AJCC v7,Colon Signet Ring Cell Adenocarcinoma | 2005-08-04 | 2022-10-01 | National Cancer Institute (NCI) | No |
| PACTR202111766112898 | ZAF |
Manor Medical Center; Sandton; |
Peripheral venous line placement: Procedural Simulation vs. Standard Patient (Randomized trial) | RCT | Patient Simulation | 2022-01-02 | 1970-01-01 | Honoris United Universities | No | |
| NCT04767139 | GHA |
Greater Accra Regional Hospital; Accra; (RIDGE) |
EPI, a Missed Opportunity for Postpartum Family Planning Utilization | Observational | Contraception | 2020-02-01 | 2021-02-28 | Hawassa University | No | |
| NCT04835454 | EGY |
Assiut University; Assiut; |
Role of Piwi-protein Interacting RNA, miRNA-194 and Amino Acids in Patients With Prostate Cancer | Observational | Finding New Biomarkers That Could be Evaluated in Patients With Prostate Cancer and Clarify Their Role in Early Detection of Prostate Cancer | 2021-05-15 | 2021-12-15 | Assiut University | No | |
| NCT04038060 | The PrEP (Pre-exposure Prophylaxis) SMART Study | Interventional | Phase 4 | HIV/AIDS | 2019-05-16 | 2022-03-01 | University of Washington | No | ||
| NCT04715789 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
COGNITIVE BEHAVIOURAL THERAPY FOR TREATMENT OF CHRONIC NON-SPECIFIC LOW BACK PAIN | Interventional | Not Applicable | Low Back Pain | 2020-10-20 | 2021-09-01 | Cairo University | No |
| NCT05316818 | EGY |
Kasr El-Aini Hospital - Kasr El Aini Faculty of Medicine Cairo University; El Azab; |
Triplet (FOLFOXIRI) vs. Doublet (FOLFOX or FOLFIRI) Regimen as a 1st Line Treatment in Metastatic Colorectal Carcinoma | Interventional | Phase 2 | Metastatic Colorectal Cancer | 2018-01-16 | 2021-04-10 | Kasr El Aini Hospital | No |
| PACTR201110000324321 | MWI |
Malawi Clinical Research Site; Lilongwe; |
Health effects of an improved cookstove intervention in Malawi: A Pilot Randomised Controlled Trial | RCT | Eye Diseases,Injury, Occupational Diseases, Poisoning,Musculoskeletal Diseases,Respiratory,Short-term ocular and respiratory symptoms, headache, backache and burns | 2011-10-10 | 2012-10-10 | Liverpool School of Tropical Medicine | No | |
| NCT04751071 | Nigeria |
Department of Clinical Pharmacy and Pharmacy Management - Nnamdi Azikwe University; Awka; |
The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients | Interventional | Phase 1,Phase 2 | Major Depressive Disorder | 2021-02-01 | 2022-12-01 | Sadat City University | No |
| NCT05512923 | Burkina Faso |
Centre de Recherche en Santé de Nouna - Ministère de la Santé; Nouna; (CRSN) |
Incidence and Risk Factors of Venous Thrombosis of the Lower Limbs After Hospitalization in Medical Patients at Risk | Observational | Patients Hospitalized for More Than 48 Hours for Acute Medical Illness | 2021-08-15 | 2023-09-30 | University of Monastir | No | |
| NCT03514459 | ZWE |
Spilhaus Clinical Research Site - Zimbabwe National Family Planning Council Clinic; Harare; (ZNFPC CRS) |
Testing an Implementation Science Tool to Increase Cervical Cancer Screening in Mombasa, Kenya | Interventional | Not Applicable | Cervical Cancer | 2020-01-29 | 2022-10-01 | University of Washington | No |
| NCT04795830 | EGY |
Dermatology Department - Ain Shams University; Cairo; |
Bioactive Materials in Pulp Therapy of Primary Teeth | Interventional | Phase 4 | Pulpitis,Pulp Disease, Dental | 2021-08-01 | 2023-03-01 | Ain Shams University | No |
| NCT02446132 | South Africa, ZAF |
Cape Trial Centre; Bellville; Apollo Clinical Research; Johannesburg; |
Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type | Interventional | Phase 3 | Agitation in Patients With Dementia of the Alzheimer's Type | 2015-12-01 | 2023-10-01 | Avanir Pharmaceuticals | No |
| NCT04154007 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Acute Kidney Injury in Patients With Acute Respiratory Distress Syndrome | Observational | Acute Kidney Injury,Acute Respiratory Distress Syndrome | 2017-09-01 | 2019-03-30 | Zagazig University | No | |
| NCT00003881 | Trastuzumab Plus Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer | Interventional | Phase 2 | Lung Cancer | 1999-05-01 | 2004-07-01 | Eastern Cooperative Oncology Group | No | ||
| NCT04384614 | TUN |
Eshmoun Clinical Research Centre; Tunis; |
Covid-19 In Tunisia: An Observational Cross-Sectional Registry Study | Observational | Covid 19,BCG Vaccination | 2020-05-15 | 2020-07-15 | Direction des Soins de Santé de Base | Yes | |
| NCT04996498 | EGY |
Ain Shams University; Cairo; |
Hemostatic Effect of Intrauterine Instillation of Oxytocin in Hysteroscopic Myomectomy | Interventional | Not Applicable | Leiomyoma | 2021-04-15 | 2022-10-01 | Ain Shams Maternity Hospital | No |
| NCT02580344 | EGY |
Assiut University; Assiut; |
The Effect of Ibuprofen on Intrauterine Contraceptive Device Associated Uterine Bleeding | Interventional | Phase 2 | Contraception | 2015-10-01 | 2016-11-01 | Assiut University | No |
| NCT05347173 | EGY |
Mansoura University Hospitals; Mansoura; |
Dexmedetomidine Versus Nalbuphine as an Adjuvant to Intrathecal Bupivacaine | Interventional | Not Applicable | Analgesia | 2022-06-21 | 2023-10-31 | Mansoura University | No |
| NCT02421302 | Uganda, ZAF |
Infectious Diseases Institute; Kampala; (IDI) Mildmay International Centre Kampala; Kampala; Africa International Research Clinical Trials (Pty) Ltd; Cape Town; |
The Pediatric HIV Nutrition Study in Uganda | Interventional | Not Applicable | Child Nutrition Disorders | 2015-02-01 | 2016-04-01 | Infectious Diseases Institute | No |
| NCT04263116 | Balloon-Assisted Maturation of Autogenous Arteriovenous Fistulae | Interventional | Not Applicable | Hemodialysis Access Failure | 2017-07-25 | 2019-05-30 | Mansoura University | No | ||
| NCT01023789 | EGY, ZAF |
Cairo University Hospital; Cairo; Netcare Moot General Hospital; Pretoria; |
ABSORB EXTEND Clinical Investigation | Interventional | Not Applicable | Coronary Disease,Coronary Restenosis,Myocardial Ischemia,Cardiovascular Disease,Coronary Artery Disease,Coronary Artery Stenosis | 2010-01-01 | 2016-10-01 | Abbott Medical Devices | No |
| NCT04144062 | NGA |
Ahmadu Bello University Teaching Hospital; Zaria; (ABUTH) |
Primary Molars Restoration Using CAD/CAM Crowns. | Interventional | Not Applicable | Restoration of Primary Molars With CAD/CAM Crowns | 2019-11-25 | 2021-02-20 | Ahmad Elheeny | No |
| NCT05538637 | GHA |
Military Hospital; Accra; |
Is Mitral Velocity Time-integral a Marker of Preload-responsiveness in Patients With Acute Circulatory Failure? | Observational | Preload-responsiveness | 2022-09-12 | 2023-05-12 | Avicenna Military Hospital | No | |
| NCT04781257 | ZWE, TZA |
Biomedical Research and Training Institute; Harare; (BRTI) National Institute for Medical Research - Mbeya Medical Research Center; Mbeya; (MMRC NIMR) |
Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries | Observational | Tuberculosis | 2021-03-01 | 2023-12-01 | Michael Hoelscher | No | |
| NCT03887975 | EGY |
Ain Shams University; Cairo; |
T-Scan Study of Occlusion in Case of Implant Retained Overdenture | Interventional | Not Applicable | Edentulous Alveolar Ridge,Dental Occlusion, Traumatic | 2018-02-20 | 2019-02-01 | Ain Shams University | No |
| NCT00116298 | Rollover Study for Zerit (Stavudine) ER Studies (-096, -099) | Interventional | Phase 3 | AIDS,HIV Infections | 2001-01-01 | 2005-01-01 | Bristol-Myers Squibb | No | ||
| NCT04431726 | KEN, ZAF, South Africa, AGO, TUN, Uganda, Egypt, EGY, NGA, GIN, UGA |
Department of Paediatrics - Alupe University College; Busia; Charlotte Maxeke Johannesburg Academic Hospital; Johannesburg; (CMJAH) Louis Pasteur Hospital; Pretoria; Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS) Department of Haematology and Cell Biology - University of the Free State; Bloemfontein; HIV Clinical Research Unit - University of Witwatersrand; Johannesburg ; (CHRU WITS) Instituto de Combate e Controlo das Tripanossomiases; Luanda; (ICCT) Manor Medical Center; Sandton; Arthritis Clinical Research Trials; Cape Town; Service Haematologie - Hopital Militaire de Tunis; Tunis; Mbale Regional Referral Hospital; Mbale; Paediatric Hospital - Cairo University; Cairo; Abu Rish Children's Hospital; Cairo; Department of Medical Microbiology Parasitology - College of Medicine University of Ibadan; Oyo; Laboratoire Des Fièvres Hémorragiques Guinea; Conakry; St. James's Hospital Life Health; East London; Amudat Hospital; Amudat; Rheumatology Department Faculty of Medicine - Ain Shams University; El Mohamady; Service de Rhumatologie - Hôpital La Rabta; Sfax; |
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors | Interventional | Phase 3 | Severe Hemophilia A | 2021-02-04 | 2029-12-16 | Hoffmann-La Roche | No |
| PACTR202205826916525 | TZA |
Nyamagana District Hospital; Mwanza; |
Examining the Effectiveness of Mobile Telephone Communication Interventions on the Utilization of Antenatal Care Services Among Expectant Mothers in the Districts of Rakai and Kyotera in Uganda: Study Protocol for a Randomized Controlled Trial. | RCT | Obstetrics and Gynecology | 2022-03-01 | 2022-05-12 | The Regional Universities Forum for Capacity Building in Agriculture | No | |
| NCT05024682 | EGY |
Sadmawy Hospital - Zagazig University; Zagzig; |
Pulsed Radiofrequency Versus Pulse Dose Pulsed Radiofrequency of the Pudendal Nerve in Patients With Pudendal Neuralgia | Interventional | Not Applicable | Pain, Chronic | 2022-01-03 | 2023-02-03 | Assiut University | No |
| NCT05295251 | DZA |
CHU Hussein Dey Alger; Alger; |
Acute Abdomen (Non-surgical and Surgical Causes) in Adults With COVID-19 | Observational | Acute Abdomen | 2020-05-01 | 2022-02-28 | Zagazig University | Yes | |
| NCT05207683 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Pulmonary Hypertension in Patients Attending Sohag University Hospital: A Focus on The Etiology | Observational | Patients With Pulmonary Hypertension | 2021-10-01 | 2022-09-01 | Sohag University | No | |
| NCT02573324 |
University of Cape Town; Cape Town; |
A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification | Interventional | Phase 2,Phase 3 | Gliosarcoma,Glioblastoma | 2015-12-07 | 2022-04-04 | AbbVie | No | |
| NCT05039125 | Comparison Between The Effects Of Different Frequencies Of Ultrasonic Cavitation On Abdominal Adiposity And Female Hormones In Polycystic Ovarian Syndrome | Interventional | Not Applicable | Polycystic Ovary Syndrome | 2018-04-30 | 2021-08-02 | Cairo University | No | ||
| NCT03295487 | ToT and Estrogen in Postmenopausal Females | Interventional | Phase 2,Phase 3 | Postmenopausal Disorder,Stress Urinary Incontinence | 2017-03-01 | 2017-09-30 | Kasr El Aini Hospital | No | ||
| NCT05559190 | Effect of a Preoperative Pulsed Electromagnetic Field and Abdominal Exercises on Muscle Strength Post Ventral Hernioplasty | Interventional | Not Applicable | Hernia, Ventral | 2021-01-01 | 2022-11-10 | Cairo University | No | ||
| NCT04339049 | NGA |
Ahmadu Bello University Teaching Hospital; Zaria; (ABUTH) |
Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD Insertion | Interventional | Phase 3 | Contraception | 2020-05-01 | 2021-07-30 | Cairo University | No |
| PACTR201408000867421 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Probiotics for Prophylaxis of postoperative Hirschsprungs Associated Enterocolitis | RCT | Digestive System,Hirschsprung,Surgery | 2014-01-08 | 1970-01-01 | Cairo University Pediatric Hospital | No | |
| NCT04721964 | ETH |
Hawassa University Referral Hospital; Awassa; |
Evaluation of the Effects of Routine Iron Supplementation in Children on Gastrointestinal Iron Losses | Interventional | Not Applicable | Iron-deficiency,Iron Deficiency Anemia,Gastro Intestinal Bleeding | 2021-02-25 | 2021-06-16 | Swiss Federal Institute of Technology | No |
| NCT03413579 | Evaluate Efficacy of the Association Nimotuzumab(HR3) /Cisplatin-Vinorelbine on Patients With Cervical Carcinom | Interventional | Phase 3 | Cervical Cancer | 2015-11-01 | 2021-12-01 | El Kendi Pharmaceuticals Manufacturing Company | No | ||
| NCT04147845 | Transepidermal Delivery of Triamcinolone Acetonide or Platelet Rich Plasma Using Either Fractional Carbon Dioxide Laser or Microneedling in Treatment of Alopecia Areata | Interventional | Not Applicable | Alopecia Areata | 2019-10-30 | 2020-11-27 | Alexandria University | No | ||
| NCT05310929 | EGY |
Ain Shams University; Cairo; |
Nitroglycerin Versus Labetalol in Acute Severe Pre-eclampsia | Interventional | Not Applicable | Severe Pre-eclampsia | 2019-08-28 | 2022-03-25 | Ain Shams University | No |
| NCT03646981 | TZA, ETH |
Nyamagana District Hospital; Mwanza; Leishmania Research and Treatment Center - Arba Minch General Hospital; Arba Minch; (LRTC) |
Evaluation of Antibody Detection Tests for Visceral Leishmaniasis Diagnosis in Eastern Africa | Observational | Leishmaniasis, Visceral | 2019-09-01 | 2021-12-01 | Foundation for Innovative New Diagnostics, Switzerland | No | |
| NCT02242799 | Uganda |
Infectious Diseases Institute; Kampala; (IDI) |
Dolutegravir Interactions With Artemisinin-based Combination Therapies | Interventional | Phase 1 | HIV,Malaria | 2015-06-01 | 2016-09-01 | University of Liverpool | No |
| NCT04617249 | EGY |
Dar Al Fouad Hospital; Giza; |
Median and Paramedian Anesthesia in Cesarean Section | Interventional | Not Applicable | Anesthesia | 2020-11-05 | 2021-05-15 | Aljazeera Hospital | No |
| NCT05277506 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
Smile Arc Assessment in Orthodontic Patients Following Smile Arc Protection VS MBT Placement Guide Bonding Strategies | Interventional | Not Applicable | Orthodontic Appliance Complication | 2022-01-10 | 2022-09-01 | Cairo University | No |
| NCT03893097 |
Institut De Recherche En Santé De Surveillance Épidémiologique Et De Formation; Rufisque; (IRESSEF) |
Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children | Interventional | Phase 3 | Schistosoma Mansoni,Schistosoma Haematobium | 2019-10-14 | 2021-03-04 | Institute of Tropical Medicine, Belgium | No | |
| NCT05311839 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Effect of Thera Band Exercises on Adhesive Capsulitis Post Mastectomy | Interventional | Not Applicable | Adhesive Capsulitis of Shoulder | 2021-01-10 | 2022-01-05 | Maged Basha | No |
| NCT00123474 | EGY, KEN, ZAF, South Africa, NGA, SEN, Nigeria, BWA, MWI, Togo, GHA, Malawi, UGA |
Clinical Research Center - Cairo University; Giza; International Cancer Institute; Uasin Gishu; Department of Medicine - University of Cape Town; Cape Town; Hopelands Cancer Centre; Durban; Manor Medical Center; Sandton; Department of Radiotherapy - Addington Hospital; Durban; Africa Health Research Institute; Durban; (AHRI) College of Medicine - University of Lagos; Lagos; Mary Potter Oncology Centre; Pretoria; Boland Ethical Research Group; Western Cape; Niakhar Demographic Surveillance System; Dakar;(DS IDR) Western Cape Clinical Trials; Western Cape; Department of Paediatrics - University of Calabar; Calabar; Life Flora Clinic; Roodepoort; Murtala Muhammad Specialist Hospital; Kano; George Clinical Study Site; George; University of Botswana/McMAsters University; Gaborone; University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC) The Oncology Centre - Onco Care Specialist Oncologists; Durban; University Of Lome; Lome; University Of Health And Allied Sciences; Ho Volta Region; Cancer Centre - Tanta University; Tanta; College of Medicine - University of Malawi; Blantyre; Damien Foundation; Abuja; Mont Amba Medical Center - University of Kinshasa; Lemba; |
Chronic Myelogenous Leukemia (CML) - Follow on: Study of BMS-354825 in Subjects With CML | Interventional | Phase 3 | Myeloid Leukemia, Chronic, Chronic-Phase | 2005-07-01 | 2014-07-01 | Bristol-Myers Squibb | No |
| NCT04872088 | NER |
Madarounfa Health District; Niger; |
Integrated Research on Acute Malnutrition in Mali (IRAM-MALI) | Interventional | Not Applicable | Wasting,Acute Malnutrition in Childhood | 2021-05-06 | 2022-04-15 | International Food Policy Research Institute | No |
| NCT04598165 | GMB, KEN |
Sukuta Health Center; Brikama; Kisumu County Hospital; Kisumu; Bondo Clinic - Bondo District Hospital; Bondo; Mathare North City Clinic; Nairobi; |
Mobile WACh NEO: Mobile Solutions for Neonatal Health and Maternal Support | Interventional | Not Applicable | Depression,Neonatal Death,Perinatal Death | 2020-09-07 | 2023-02-28 | University of Washington | No |
| NCT04475809 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Different Maneuvers for Reducing Post-laparoscopic Pain | Interventional | Not Applicable | Gynecologic Disease | 2020-07-13 | 2022-03-01 | Zagazig University | No |
| NCT04933877 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Comparing Serratus Anterior Plane Block With Erector Spinae Plane Block for Thoracotomy in Pediatric Patients | Interventional | Not Applicable | Anesthesia | 2021-03-01 | 2022-01-01 | Cairo University | No |
| NCT04705493 | EGY |
Kasr El-Aini Hospital - Kasr El Aini Faculty of Medicine Cairo University; El Azab; |
Validation of Uncalibrated Cardiac Output Measurement With LiDCOrapid in the Resuscitation of Critically Ill Patients With Septic Shock: A Prospective Cross-sectional Study. | Observational | Cardiac Output, LIDCO Rapid, Septic Shock | 2019-12-01 | 2021-07-01 | Cairo University | No | |
| PACTR202007606032743 | Egypt |
15th of May Hospital; Cairo; |
Nebulized heparin in patients with mainly moderate coronavirus disease 2019: Randomized controlled trial. COVID-19 | RCT | Infections and Infestations | 1970-01-01 | 1970-01-01 | Dr Tarek Ismail | Yes | |
| NCT03009526 | Malawi |
Malaria Alert Center - University of Malawi; Blantyre; |
Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi | Interventional | Phase 3 | Malaria,Pregnancy | 2017-01-17 | 2018-10-24 | University of Malawi College of Medicine | No |
| NCT03269851 | EGY |
Assiut University; Assiut; |
Parameters of Neurological Deficit After Thoracolumbar Fractures | Observational | SPINAL Fracture | 2018-11-01 | 2020-03-21 | Assiut University | No | |
| NCT05156138 | EGY |
Assiut University; Assiut; |
The Possible Association Between Pseudoexfoliation Syndrome And Corneal Endothelial Cell Changes | Observational | Pseudoexfoliation Syndrome | 2022-01-24 | 2022-09-24 | Assiut University | No | |
| NCT04516811 | ZMB, ZAF |
St. Pauls Mission Hospital; Nchelenge; Universitas Hospital; Bloemfontein; |
Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19 | Interventional | Phase 3 | COVID-19,SARS-CoV-2 Infection,Severe Acute Respiratory Syndrome Coronavirus 2 | 2020-09-21 | 2022-07-31 | South African National Blood Service | Yes |
| NCT02145468 | A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60) | Interventional | Phase 3 | Acute Coronary Syndrome | 2014-06-03 | 2015-12-14 | GlaxoSmithKline | No | ||
| NCT04679779 | EGY |
Egypt Air Hospital; Cairo; |
Virtual Reality in Children With Hemiparesis | Interventional | Not Applicable | Physical Disability | 2020-12-01 | 2021-02-15 | Cairo University | No |
| NCT02994030 | EGY |
Ain Shams University; Cairo; |
Biomarker for Duchenne Muscular Dystrophy | Observational | Lordosis,Scoliosis,Hyporeflexia,Muscular Atrophy,Muscular Weakness,Red-Green Color Blindness,Duchenne Muscular Dystrophy,Increased Lordosis/Scoliosis | 2018-08-20 | 2022-03-11 | Centogene AG Rostock | No | |
| NCT05137210 | Kenya |
Partners in Health and Research Development; Thika; (PHRD) |
Identifying Efficient Linkage Strategies for HIV Self-Testing | Interventional | Not Applicable | Hiv | 2021-09-01 | 2025-06-15 | University of California, Los Angeles | No |
| PACTR2010060002133418 | Mozambique |
Centro de Investigação em Saúde de Manhiça; Manhica; (CISM) |
Top-Up Study | RCT | Infections and Infestations | 2010-01-06 | 1970-01-01 | Medical Research Council | No | |
| NCT04878003 | Nigeria, ZAF, Burkina Faso, TUN, NGA, Algeria, EGY, GHA, NAM |
First Technical University; Ibadan; Garden City Clinic; Johannesburg; Hopelands Cancer Centre; Durban; Instituut National de Santé Publique; Ouagadougou; (INSP) Service Haematologie - Hopital Militaire de Tunis; Tunis; Somerset West Clinical Trial Unit; Somerset West; (Ssw) Center for Clinical Care and Clinical Research; Abuja; (CCCRN) Netcare Kuils river Hospital; Cape Town; George Clinical Study Site; George; Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH) Centre Anti-Cancer; Annaba; Nariman Public Hospital; Bab Sharq-Wabour El Meiah; Military Hospital; Accra; Medical Centre; Erongo; Nelson Mandela Academic Hospital - Mthatha Hospital Complex; Eastern Cape; |
Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis | Interventional | Phase 2 | Primary Myelofibrosis (PMF),Post-Polycythemia Vera Myelofibrosis (Post-PV-MF),Post-Essential Thrombocythemia Myelofibrosis (Post-ET-MF) | 2021-04-13 | 2025-10-01 | Kartos Therapeutics, Inc. | No |
| NCT04338321 | DZA |
Centre Hospitalo-Universitaire d'Oran; Oran; (CHU) |
A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder | Interventional | Phase 3 | Depressive Disorder, Major | 2020-08-21 | 2022-07-27 | Janssen-Cilag International NV | No |
| NCT03508778 | Clinical Evaluation of the FluidVision Accommodation Intraocular Lens (AIOL) | Interventional | Not Applicable | Cataract | 2018-02-27 | 2019-12-06 | PowerVision | No | ||
| NCT00553410 | ZAF |
Tygerberg Hospital; Parrow; |
Letrozole in Preventing Cancer in Postmenopausal Women Who Have Received 4-6 Years of Hormone Therapy for Hormone Receptor-Positive, Lymph Node-Positive, Early-Stage Breast Cancer | Interventional | Phase 3 | Breast Cancer | 2007-08-01 | 2019-05-15 | International Breast Cancer Study Group | No |
| NCT01899742 | The Purpose of the This Study is to Evaluate the Spirometric Effect (Trough FEV1) of Umeclidinium/Vilanterol 62.5/25 mcg Once Daily Compared With Tiotropium 18mcg Once Daily Over a a 12-week Treatment Period in Subjects With COPD Who Continue to Have Symptoms on Tiotropium | Interventional | Phase 3 | Pulmonary Disease, Chronic Obstructive | 2014-09-15 | 2015-07-22 | GlaxoSmithKline | No | ||
| PACTR201704002216259 | South Africa |
A Mamabolo Clinic; Polokwane; |
M-Health and Maternal Health care Services Use | RCT | Maternal Health,Pregnancy and Childbirth | 2017-01-08 | 2018-02-04 | Haramaya University | No | |
| NCT04941209 | BEN, ETH |
Laboratoire de Référence des Mycobactéries; Benin; Ethiopian Public Health Association; Addis Ababa; |
imPulse™ Una Infrasound-to-ultrasound E-stethoscope | Observational | Covid19,Mass Screening,COVID-19 Pneumonia,Corona Virus Infection,Vaccine Virus Shedding,COVID-19 Respiratory Infection,COVID-19 Acute Respiratory Distress Syndrome | 2021-06-11 | 2022-02-28 | Level 42 AI, Inc. | Yes | |
| PACTR201803003177455 | A Randomized Controlled Trial of Rational Emotive Behavior Therapy Program on Depressive Symptoms among University Students with Blindness in Nigeria | RCT | Depression,Eye Diseases,Mental and Behavioural Disorders | 1970-01-01 | 1970-01-01 | Liziana N. Onuigbo , Chiedu Eseadi, Samuel Ebifa, Uchenna Cosmas Ugwu, Charity N, Onyishi, Eke Kalu Oyeoku | No | |||
| NCT01123551 | Efficacy Study of Nebulized Morphine and Intravenous Morphine in Post Traumatic Pain | Interventional | Phase 3 | Post Traumatic Pain | 2010-06-01 | 2014-07-01 | University of Monastir | No | ||
| NCT00003808 | Theophylline in Treating Patients With In Situ, Stage I, or Stage II Chronic Lymphocytic Leukemia | Interventional | Phase 2 | Leukemia | 1999-05-01 | Eastern Cooperative Oncology Group | No | |||
| NCT00002823 | BDI, ZAF |
Institut National d'Oncologie; Bujumbura; Universitas Hospital; Bloemfontein; |
Combination Chemotherapy Compared With No Treatment Following Surgery in Treating Patients With Non-small Cell Lung Cancer | Interventional | Phase 3 | Lung Cancer | 1995-02-01 | Gustave Roussy, Cancer Campus, Grand Paris | No | |
| PACTR201907849473370 | RWA |
College of Medicine and Health Sciences; Gasabo; |
FALCON Protocol | RCT | Surgery | 1970-01-01 | 1970-01-01 | University of Birmingham | No | |
| NCT04909918 | EGY |
Assiut University; Assiut; |
Impact of Steroids on Inflammatory Response in Covid-19 | Interventional | Phase 3 | Covid19 | 2021-05-28 | 2021-08-20 | Assiut University | Yes |
| NCT05365503 | MAR |
Chókwè Health Research and Training Centre; Gaza; (CITSC) Ain Shams Research Institute; Oujda; |
Dissemination Strategies and Implementation Outcomes of Adolescent Character Strength Interventions. | Interventional | Not Applicable | Mental Health Disorder | 2022-05-09 | 2022-07-31 | Shamiri Institute | No |
| NCT03799055 | EGY |
Banha University Hospital; Qalyoubia; |
Ultrasonography vs Conventional Methods for Prediction of Difficult Airway in Adult Patients | Observational | Difficult Intubation | 2019-06-10 | 2020-01-10 | Benha University | No | |
| NCT00676143 | ZAF |
Netcare St. Augustine's Hospital; Durban; |
Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients | Interventional | Phase 3 | Alzheimer Disease | 2008-01-01 | 2012-11-01 | Pfizer | No |
| NCT03047642 | MOZ |
Instituto Nacional de Saúde; Maputo; (INS) |
Validation of Promising Biomarker Assays to Assess Their Diagnostic Performance Characteristics | Observational | Acute Febrile Illnesses | 2017-04-27 | 2019-11-27 | Foundation for Innovative New Diagnostics, Switzerland | No | |
| PACTR201803003232225 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
effect of core stability exercise on postpartum lumbopelvic pain : A randomized controlled trial | RCT | Musculoskeletal Diseases,Pregnancy and Childbirth,women with postpartum lumbopelvic pain | 1970-01-01 | 1970-01-01 | Faculty of Physical therapy, cairo university | No | |
| NCT04231344 | EGY |
Assiut University; Assiut; |
Laryngeal Disorders and GERD in Assiut University | Observational | Laryngeal Disease | 2021-01-01 | 2022-02-01 | Assiut University | No | |
| NCT00980538 | South Africa, ZAF |
JOSHA Research; Bloemfontein; FARMOVS Integrated Research Solutions; Bloemfontein; Excellentis Clinical Trial Consultants; George; Synapta Clinical Research Centre; Durban; |
TMC125-TiDP35-C239 - Continued Access to Etravirine (ETR) in Treatment Experienced HIV-1 Infected Participants | Interventional | Phase 3 | HIV-1,HIV Infections | 2009-12-01 | 2024-01-01 | Janssen Sciences Ireland UC | No |
| NCT02362503 | Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients | Interventional | Phase 3 | HIV Infections | 2015-02-23 | 2024-12-31 | ViiV Healthcare | No | ||
| NCT05525819 | Intrathecal Versus Intravenous Dexmedetomidine in Prostate Transurethral Resection | Interventional | Not Applicable | Analgesia,Dexmedetomidine,Transurethral Resection of Prostate | 2022-09-01 | 2023-04-29 | Tanta University | No | ||
| NCT04747067 | EGY |
Ain Shams University; Cairo; |
To Assess the Effect of HDF Versus High Flux Dialysis on Free Light Chains and Cumulative Albumin Loss, in End Stage Renal Disease Patients. | Observational | Hemodialysis,Hemodiafiltration,End Stage Renal Disease | 2021-02-01 | 2021-09-01 | Ain Shams University | No | |
| NCT03700749 | NGA |
Lagos University Teaching Hospital; Idi Araba; |
FALCON Trial Testing Measures to Reduce Surgical Site Infection | Interventional | Phase 3 | Abdominal Surgery,Surgical Site Infection | 2018-11-29 | 2021-07-31 | University of Birmingham | No |
| NCT05438693 | EGY |
South Valley University; Qena; Assiut University; Assiut; |
Delayed Diagnosis of Multiple Sclerosis, Treatment Initiation and Non-adherence in Upper Egypt | Observational | Multiple Sclerosis, Relapsing-Remitting | 2020-06-01 | 2022-06-01 | doaa mokhtar mahmoud | No | |
| NCT04822090 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Parvovirus B19 Infection in Hereditary Hemolytic Anemias Patients | Observational | Parvovirus B19 Infection | 2018-02-10 | 2024-02-10 | Sohag University | No | |
| NCT04683419 | EGY |
Cardiology Department - Alexandria University; Alexandria; |
Modified Thoracoscopic Pleural Cryobiopsy in Diagnosis of Exudative Pleural Effusion | Interventional | Not Applicable | Pleural Effusion | 2020-11-11 | 2021-01-15 | Alexandria University | No |
| NCT05429567 | EGY |
University Hospital - Tanta University; Tanta; |
Effectiveness of Patient-Controlled Intravenous Analgesia (PCIA) With Fentanyl | Interventional | Phase 1 | Total Hip Replacement | 2021-03-01 | 2022-02-28 | Egymedicalpedia | No |
| NCT04947215 | EGY |
Assiut University; Assiut; |
The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome | Observational | Neonatal Respiratory Distress | 2021-08-01 | 2022-07-31 | Assiut University | No | |
| NCT04552548 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children | Interventional | Not Applicable | Postoperative Pain | 2019-10-01 | 2020-12-01 | Minia University | No |
| NCT04316871 | EGY |
Assiut University; Assiut; |
Dosage of Epidural Morphine in Elderly Patients | Interventional | Phase 4 | Age Problem,Abdominal Cancer | 2020-03-20 | 2021-06-30 | Assiut University | No |
| NCT05342259 | EGY |
Ain Shams University; Cairo; |
Low Dose Caudal VS Dorsal Penile Nerve Block for Postoperative Analgesia After Circumcision | Interventional | Not Applicable | Pain, Postoperative | 2022-04-25 | 2022-08-30 | Ain Shams University | No |
| NCT04796376 | EGY |
Assiut University; Assiut; |
The Outcome of Combined Partial Fistulectomy or Fistulotomy and Cutting Seton Procedure in High Perianal Fistula | Interventional | Not Applicable | High Anal Fistula | 2020-10-10 | 2023-03-01 | Assiut University | No |
| NCT05319977 | Maternal Alcohol Reduction Intervention in South Africa [MaRISA] | Interventional | Not Applicable | Maternal; Alcohol Use, Affecting Fetus | 2021-03-05 | 2023-02-28 | RTI International | No | ||
| NCT04776889 | KEN |
International Cancer Institute; Uasin Gishu; |
The Prognosis of Lipid Reprogramming With Rosuvastatin, in Castrated Egyptian Prostate Cancer Patients | Interventional | Phase 4 | Prostate Cancer Metastatic | 2019-01-15 | 2020-12-30 | National Cancer Institute, Egypt | No |
| NCT03477136 | Serum and Semen Vitamin D Level With Semen Parameters | Observational | Vitamin D Deficiency | 2018-12-06 | 2021-04-01 | Assiut University | No | |||
| NCT04048018 | COD, ZMB, ZAF, EGY, UGA, KEN, Sierra Leone, BWA, CMR, DZA, Algeria, NGA, TZA, ZWE |
General Reference Hospital Masi Manimba Hospital; Bandundu; (HGR) Choma District Health Office; Choma; Louis Pasteur Hospital; Pretoria; TASK Mfuleni Clinical Research Centre; Mfuleni; General Reference Hospital Mushie Hospital; Bandundu; (HGR) University of the Free State; Bloemfontein; Life Flora Clinic; Roodepoort; Abu Rish Children's Hospital; Cairo; Omugo Health Centre IV; Terego; University of Nairobi College of Health Sciences - Kenyatta National Hospital; Nairobi; (KNH UON) Tuberculosis Research; Freetown; University of Botswana/McMAsters University; Gaborone; Douala General Hospital; Douala; Centre Hospitalo universitaire Bologhine Hospital; Algiers; Lung Infection And Immunity Unit - University of Cape Town; Cape Town; Hospital Central de l'Armée; Algiers; (HCA) Centre Anti-Cancer; Annaba; Moriana Clinical Research; Free State; Department of Paediatrics and Child Health - University of Ilorin Teaching Hospital; Ilorin; Mwanza Intervention Trials Unit - Tanzania National Institute for Medical Research and the London School of Hygiene and Tropical Medicine; Mwanza; (NIMR LSHTM) University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF) |
Performance Evaluation of the VIDAS TB-IGRA Assay. | Observational | Active Tuberculosis,Latent Tuberculosis Infection,Non-Tuberculous Mycobacterial (NTM) Pneumonia | 2019-12-05 | 2021-06-30 | BioMérieux | No | |
| NCT05342779 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Radio Frequency Ablation Versus Stripping of Great Saphenous Vein in Management of Primary Varicose Veins , Comparative Study | Interventional | Not Applicable | Varicose Veins | 2022-06-01 | 2023-06-01 | Sohag University | No |
| NCT05015465 | EGY |
Faculty of Medicine - Minia University; El Menia; |
AS-OCT Study of Cornea and Tear Film Parameters in Juvenile SLE Patients | Observational | Juvenile Systemic Lupus Erythematosus | 2020-07-01 | 2021-11-01 | Minia University | No | |
| NCT04863898 | Uganda, ZAF, UGA |
Mbale Regional Referral Hospital; Mbale; Montana Hospital; West Coast; NHC Health Center; Randburg; Tara Hospital; Sandton; Epicentre Mbarara Research Centre; Mbarara; |
Addressing Drug Use Stigma in HIV Care and Treatment Clinics in Tanzania | Observational | Drug Use Stigma in HIV Treatment Clinics | 2021-02-17 | 2022-12-01 | RTI International | No | |
| NCT02728232 | Internal Iliac Artery Ligation and Abnormally Invasive Placenta | Interventional | Not Applicable | Placenta Percreta | 2016-04-01 | 2017-04-01 | Cairo University | No | ||
| NCT05103410 | EGY |
Ain Shams University; Cairo; |
Impact of Aripiprazole on Postoperative Analgesia in Laparoscopic Hysterectomy | Interventional | Phase 4 | Analgesia,Anesthesia,Hysterotomy | 2021-10-21 | 2022-10-01 | Ain Shams University | No |
| NCT01215747 | ZAF, TUN |
RK Khan Hospital; Chatsworth; La Rabta hospital Tunis; Tunis; |
Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis | Interventional | Phase 3 | Amyloidosis | 2010-11-01 | 2016-03-01 | C.T. Development America, Inc. | No |
| NCT04824235 | EGY |
Ain Shams University; Cairo; |
Alveolar Ridge Preservation Using Amniotic Chorion Membrane | Interventional | Not Applicable | Alveolar Ridge Preservation | 2020-12-01 | 2022-03-01 | Hams Hamed Abdelrahman | No |
| NCT04695639 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Selective Motor Control and Upper Extremity Functions in Children With Hemiparetic Cerebral Palsy | Observational | Cerebral Palsy | 2021-02-01 | 2021-05-05 | Cairo University | No | |
| NCT03657316 | EGY |
Assiut University; Assiut; |
Impact of School Based Education Program | Interventional | Not Applicable | Diet Modification | 2019-09-01 | 2021-12-01 | Assiut University | No |
| PACTR201902680224481 | Echocardiography-guided management of hemodynamics in severe sepsis and septic shock in adults. | RCT | Circulatory System,Infections and Infestations | 2015-01-03 | 1970-01-01 | Tanta University Hospital | No | |||
| NCT04083586 | EGY |
Assiut University; Assiut; |
Pattern and Frequency of Non-epileptic Involuntary Movements | Observational | Involuntary Movements | 2020-01-15 | 2021-01-15 | Assiut University | No | |
| NCT05322369 | EGY |
NEMROCK Faculty of Medicine - Cairo University; El Azab; |
Prevalence of Periodontitis in Diabetic Patients of Egyptian Population | Observational | Diabetes,Periodontitis | 2022-05-01 | 2023-03-30 | Cairo University | No | |
| NCT05506527 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Assessment of Respiratory Function Cerebral Palsy Using Plyometric Exercise Sensorimotor Program | Interventional | Not Applicable | Cerebral Palsy | 2022-09-01 | 2023-01-01 | Egyptian Chinese University | No |
| NCT04240938 | Adult Dacryocystocele Among Patients With Epiphora | Interventional | Not Applicable | Lacrimal Passage Obstruction | 2017-03-01 | 2019-12-30 | Minia University | No | ||
| NCT05240729 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Using Ultrasound in Infraclavicular in Upper Limb Surgeries | Interventional | Not Applicable | Upper Limb Surgeries | 2021-05-24 | 2022-11-24 | Minia University | No |
| PACTR201803003078232 | GHA |
Korle Bu Teaching Hospital; Accra; |
Resistance Training and Compression Garment in the Management of Breast Cancer-Related Lymphedema | RCT | breast cancer related lymphedema,Cancer | 2015-05-02 | 1970-01-01 | Rokia M, EL-Sabagh4 | No | |
| NCT02269943 |
Salah Azaiez Institute; Tunis; |
Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal Carcinoma | Interventional | Phase 2 | Nasopharyngeal Neoplasms | 2015-02-13 | 2017-04-20 | Celgene | No | |
| NCT00084318 | EGY, GHA, COD, BWA, DZA, ZAF, KEN, MAR, Uganda, NGA, Senegal, BEN, BFA, ZWE, ETH, MWI, ZMB, UGA, TUN, CMR, Ghana, Togo, Algeria, LBR |
Clinical Research Center - Cairo University; Giza; Greater Accra Regional Hospital; Accra; (RIDGE) General Reference Hospital Masi Manimba Hospital; Bandundu; (HGR) Francistown Academic Hospital; Francistown; Al Mouneer Diabetic Retina Center; Giza; Etablissement Hospitalo-Universitaire Oran; Oran; Wilgers Medical Consortium; Pretoria; International Cancer Institute; Uasin Gishu; Clintrial Consultants; Cape Town; Molepolole BHP Study Clinic - Scottish Livingstone Hospital; Molepolole; Mediclinic Sandton; Bryanston; Louis Pasteur Hospital; Pretoria; Netcare Greenacres Hospital; Port Elizabeth; Specialty Hospital of Rabat; Rabat; Urban Comprehensive Health Centre; Ile Ife; Hopelands Cancer Centre; Durban; Manor Medical Center; Sandton; Vaal Triangle Oncology Centre - Clinical and Radiation Oncologists A.B.J. Inc; Vereeniging; Mary Potter Oncology Centre; Pretoria; Mbale Regional Referral Hospital; Mbale; Mainland Hospital; Yaba; Cooper University Hospital Clinical Research Site; Durban; Hospital General De Grand Yoff; Dakar; (HOGGY) Southern Cross Hospital; Cape Town; Centre de Pneumo-Phtisiologie d'Akron; Akron; Clinical research Unit of Nanoro - Saint Camille Medical Center of Nanoro; Ouagadougou; (CRUD - CMA) Richards Bay Trial Center - Bay Hospital; KwaZulu Natal; Deborah Retief Memorial Hospital; Mochudi; Abu Rish Children's Hospital; Cairo; South Medical Hospital; Chitungwiza; Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region; Netcare Kuils river Hospital; Cape Town; Drs Gudgeon and Boeddinghaus Associates; Cape Town; Faculty of Health Sciences - University of Cape Town; Cape Town; (UCT) Clinical Research Center - Agaro General Hospital; Agaro; (CRC) Intercare Tyger Valley Healthcare Centre; Bellville; Centre Pierre-et-Marie-Curie; Sidi M'Hamed; (CPMC) University of North Carolina lilongwe project - University of North Carolina School of Medicine and Malawi Ministry of Health; Lilongwe; (UNC) St. Pauls Mission Hospital; Nchelenge; St. George's Medical Centre; Port Elizabeth; Clinical Research Center - Faculty of Medicine Ain Shams University Research Institute; El Mohamady; Department of Radiation Oncology - University of Cape Town; Cape Town; The Oncology Centre - Onco Care Specialist Oncologists; Durban; Masaka Medical Research Council - Uganda Virus Research Institute; Entebbe; Sandton Oncology Cancer Centre; Sandton; Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH) Health Services Department - University of Benin; Benin; Centre anti-cancer d'Oran; Oran; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; Care and Health Program; Yaounde; Noguchi Memorial Institute for Medical Research; Accra; (NMIMR) University Of Lome; Lome; Honeydew Medical Centre; Roodepoort; University Of Health And Allied Sciences; Ho Volta Region; Scottish Livingstone Hospital; Molepolole; Nasser Institute for Research and Treatment; Cairo; Centre Anti-Cancer; Annaba; Jackson F. Doe Memorial Hospital; Tapeta; Service de Rhumatologie - Hospital Charles Nicolle of Tunis; Tunis; Medical and Dental Centre; Randburg; South Valley University; Qena; Hiway Medical Center; Durban; Kimberley Hospital Complex; Kimberley; Medicross Bluff Medical Center; Durban; Cancer Centre - Tanta University; Tanta; Intercare Medical and Dental Centre; Lynwood; Netcare Moot General Hospital; Pretoria; Bertoni Mercy Clinic; Pretoria; University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF) Nelson Mandela Academic Hospital - Mthatha Hospital Complex; Eastern Cape; Bishop Lavis Day Hospital; Cape Town; Watany Research and Development Center - Watany Eye Hospital; Cairo; (WEH) |
Adjuvant Cetuximab and Chemoradiotherapy Using Either Cisplatin or Docetaxel in Treating Patients With Resected Stage III or Stage IV Squamous Cell Carcinoma or Lymphoepithelioma of the Head and Neck | Interventional | Phase 2 | Head and Neck Cancer | 2004-04-01 | 2016-12-01 | Radiation Therapy Oncology Group | No |
| PACTR202206670556358 | ZAF |
National District Hospital; Bloemfontein; |
The TraD Trial | RCT | Anaesthesia,Obstetrics and Gynecology | 2022-10-07 | 2022-10-09 | Ministry of Health | No | |
| NCT05045443 | EGY |
Rheumatology Department Faculty of Medicine - Ain Shams University; El Mohamady; |
Safety and Efficacy of Curcumin in Children With Acute Lymphoblastic Leukemia | Interventional | Phase 2 | Acute Lymphoblastic Leukemia, Pediatric | 2021-08-22 | 2022-09-01 | Ain Shams University | No |
| NCT03449810 | Nigeria |
Murtala Muhammad Specialist Hospital; Kano; |
Effectiveness of Muscles Energy Technique in the Management of Chronic Non-specific Low Back Pain | Interventional | Not Applicable | Chronic Non-specific Low Back Pain | 2019-01-01 | 2019-12-20 | University of KwaZulu | No |
| NCT03411928 | Endotracheal Dilator to Improve Oxygenation | Interventional | Not Applicable | Airway Disease,Tracheal Stenosis,Pediatric Respiratory Diseases | 2018-09-01 | 2018-12-30 | University of Cape Town | No | ||
| NCT05035303 | EGY |
Banha University Hospital; Qalyoubia; |
Can Trajectory Nor-epinephrine Infiltration Reduce Blood Loss During Percutaneous Nephrolithotomy (PCNL)? | Interventional | Not Applicable | Blood Loss, Surgical | 2020-03-10 | 2022-01-01 | Benha University | No |
| NCT04769635 | DZA |
Centre Hospitalier Universitaire Sidi Bel abbas; Sidi Bel Abbès; (CHU) |
CPAP Therapy in Obstructive Sleep Apnea Patients With Pulmonary Hypertension | Interventional | Not Applicable | Pulmonary Hypertension | 2019-10-15 | 2020-10-15 | Zagazig University | No |
| NCT04764058 | EGY |
Ain Shams University; Cairo; |
Efficacy and Safety of Colistin Based Antibiotic Therapy | Interventional | Phase 1,Phase 2 | Septicemia,Bacterial Infections | 2017-09-01 | 2021-09-01 | Ain Shams University | No |
| NCT05330650 | ZAF |
Department of Paediatrics and Child Health; Panorama; |
Evaluation of Triclosan Coated Suture in Obstetrical Surgery | Interventional | Phase 4 | Cesarean Section; Infection | 2020-11-01 | 2021-06-30 | Tunis University | No |
| NCT05122351 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Comparative Study Between The Efficacy Of Quadratus Lumborum Block VS Conventional Analgesia In Patients Undergoing Open Inguinal Hernia Surgical Repair | Interventional | Early Phase 1 | Analgesia in Patients With Open Inguinal Hernia Surgeries | 2021-10-01 | 2022-02-01 | Sohag University | No |
| NCT01510574 | UGA, Uganda, NGA |
Kasangati Health Center IV; Wakiso; Mbale Regional Referral Hospital; Mbale; Central Primary Health Centre; Akahia; Mulanda Health Centre IV; Tororo; |
A Study of Self-administered Misoprostol to Prevent Bleeding After Childbirth in the Community (MamaMiso) | Interventional | Not Applicable | Postpartum Hemorrhage | 2012-05-01 | 2012-10-01 | Gynuity Health Projects | No |
| NCT00002632 | Paclitaxel in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer | Interventional | Phase 2 | Head and Neck Cancer | 1995-03-01 | Eastern Cooperative Oncology Group | No | |||
| NCT00819156 | ZAF |
Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS) The Urology Hospital; Pretoria; |
Dose Finding Trial With a New Treatment (Degarelix) for Prostate Cancer | Interventional | Phase 2 | Prostate Cancer | 2004-02-01 | 2005-09-01 | Ferring Pharmaceuticals | No |
| NCT05249478 | EGY |
Ain Shams University; Cairo; |
Pain Management After Total Knee Replacement | Interventional | Not Applicable | Post Operative Pain | 2022-02-05 | 2022-08-01 | Ain Shams University | No |
| NCT03601806 | TZA, KEN |
Bugando medical Centre; Mwanza; School of Medicine - Moi University; Eldoret; |
Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection | Interventional | Phase 2 | Skin Kaposi Sarcoma,Human Immunodeficiency Virus 1 Positive | 2021-04-26 | 2023-10-30 | AIDS Malignancy Consortium | No |
| NCT01600781 | Egypt |
Children’s Cancer Hospital Egypt 57357; Cairo; |
Effect of Oral Supplementation With a Fibre Enriched Paediatric Sip Feed For Children With Acute Lymphocytic Leukemia | Interventional | Not Applicable | Acute Lymphocytic Leukemia | 2011-12-01 | 2014-09-01 | Children's Cancer Hospital Egypt 57357 | No |
| NCT02859350 | Equatorial Guinea |
La Paz Medical Center; Malabo; |
Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea. | Interventional | Phase 1 | Malaria | 2016-11-01 | 2018-02-01 | Sanaria Inc. | No |
| NCT05012787 | , ZAF, South Africa |
University of Cape Town; Cape Town; Universitas Hospital; Bloemfontein; Desmond Tutu HIV Foundation; Cape Town; |
A Study of Safety and Immunogenicity of Adjuvanted SARS-CoV-2 (SCB-2019) Vaccine in Adults With Chronic Immune-Mediated Diseases | Interventional | Phase 3 | COVID-19 | 2021-09-13 | 2022-12-16 | Clover Biopharmaceuticals AUS Pty Ltd | Yes |
| NCT05132153 | TZA |
Handeni Clinical trial site (Joint Malaria Programme) - Kilimanjaro Christian Medical University College; Kilimanjaro; (KCMC) |
Effect of Nebulized Milrinone on Right Ventricular Hemodynamics in Adult Cardiac Surgery | Interventional | Phase 4 | Anesthesia | 2021-10-17 | 2022-09-20 | Ain Shams University | No |
| NCT02206451 | MLI |
Malaria Research and Training Center - University Of Bamako; Bamako; (MRTC) |
Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Mali | Observational | Malaria | 2014-07-16 | 2014-07-16 | National Institute of Allergy and Infectious Diseases (NIAID) | No | |
| NCT05050071 | EGY |
Cardiology Department - Suez Canal University; Ismailia; |
Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth | Interventional | Phase 2,Phase 3 | Drug Effect | 2019-10-08 | 2021-07-17 | Suez Canal University | No |
| NCT04832932 | ZWE, UGA, ZAF, BWA |
South Medical Hospital; Chitungwiza; Medical Research Council Uganda Virus Research Institute Research Unit on AIDS; Entebbe; Africa International Research Clinical Trials (Pty) Ltd; Cape Town; Gaborone Clinical Research Site; Gaborone; |
The COVID-19 Back-to-Normal Study | Observational | COVID-19 Vaccines | 2021-06-15 | 2023-04-15 | Mebo Research, Inc. | Yes | |
| NCT04894630 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Infective Keratitis in Minia Governate | Interventional | Not Applicable | Infective Keratitis | 2018-12-01 | 2020-12-31 | Minia University | No |
| NCT04822428 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Effect of Visceral Osteopathic Manipulations on Low Back Pain | Interventional | Not Applicable | Low Back Pain | 2020-08-20 | 2021-03-12 | Cairo University | No |
| NCT00562965 | Study Comparing Inotuzumab Ozogamicin In Combination With Rituximab Versus Defined Investigator's Choice In Follicular Non-Hodgkin's Lymphoma (NHL) | Interventional | Phase 3 | Lymphoma, Follicular | 2007-11-01 | 2011-04-01 | Pfizer | No | ||
| NCT05364138 | Kenya |
Partners in Health and Research Development; Thika; (PHRD) |
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda | Observational | Breast Cancer,Cervix Cancer,Benign Breast Disease | 2022-09-15 | 2023-12-31 | Brigham and Women's Hospital | No | |
| PACTR201106000304583 | A Phase I trial to assess safety and immunogenicity of i.d. DNA priming and i.m. MVA boosting in healthy volunteers in Mozambique | RCT | Infections and Infestations | 1970-01-01 | 1970-01-01 | Swedish Institute for Infectious Disease Control | No | |||
| NCT02105974 | Study Evaluating the Efficacy and Safety of Fluticasone Furoate/Vilanterol Inhalation Powder (FF/VI) Compared With Vilanterol Inhalation Powder (VI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD) | Interventional | Phase 3 | Pulmonary Disease, Chronic Obstructive | 2014-04-07 | 2015-07-08 | GlaxoSmithKline | No | ||
| NCT04319380 | MLI, Burkina Faso, BFA |
Malaria Research and Training Center - University Of Bamako; Bamako; (MRTC) Institut de Recherche en Sciences de la Santé; Bobo-Dioulasso; (IRSS) Institut de Recherche en Science de la Sante; Boulkiemdé; |
Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study | Interventional | Phase 3 | Child, Only,Malaria,Falciparum | 2020-06-05 | 2022-03-31 | London School of Hygiene and Tropical Medicine | No |
| NCT04615702 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Evidence Based Management of Acute Biliary Pancreatitis | Observational | Acute Pancreatitis | 2017-05-15 | 2019-05-15 | Zagazig University | No | |
| NCT01388452 | MWI |
Kamuzu Central Hospital; Lilongwe; |
HIV Diagnosis in Hospitalized Malawian Infants | Interventional | Not Applicable | HIV Infections | 2011-06-01 | 2012-12-01 | University of North Carolina, Chapel Hill | No |
| NCT05050825 | BEN, ZAF, KEN |
Centre de Diagnostic et de Traitement de la Tuberculose de Djougou; Djougou; TASK Delft Clinical Research Centre; Delft; Siaya District Hospital; Siaya; |
Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal | Interventional | Not Applicable | Dengue,Malaria,Diarrhea,Pneumonia,Acute Febrile Illness,Influenza -Like Illness | 2021-05-03 | 2021-12-15 | Foundation for Innovative New Diagnostics, Switzerland | No |
| NCT00054561 | Isotretinoin, Interferon Alfa, and Vitamin E in Treating Patients With Stage III or Stage IV Head and Neck Cancer | Interventional | Phase 3 | Head and Neck Cancer | 2003-08-01 | 2009-05-01 | Eastern Cooperative Oncology Group | No | ||
| NCT04796610 | Mopati: A Pilot Hiv Treatment Partner Intervention In Botswana | Interventional | Not Applicable | HIV | 2021-06-17 | 2023-06-30 | RAND | No | ||
| NCT01717885 | UGA |
Tororo District Hospital; Tororo; Infectious Diseases Research Collaboration; Tororo; (IDRC) |
Antimalarial Pharmacology in Children and Pregnant Women in Uganda | Observational | HIV,Malaria | 2012-08-01 | 2016-09-01 | University of California, San Francisco | No | |
| NCT04625192 | Trephine Osteotomy in Lateral Sinus Lift | Interventional | Not Applicable | Sinus Lift | 2020-02-01 | 2021-01-30 | Hams Hamed Abdelrahman | No | ||
| NCT05331924 | Quality of Life Improvement in Dry Eye Patients After Intense Pulsed Light Therapy Compared to Punctal Plugs | Interventional | Not Applicable | Evaporative Dry Eye | 2020-12-01 | 2022-02-01 | Tanta University | No | ||
| NCT05275634 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Interferential Current And Trapezius Myofascial Trigger Points | Interventional | Not Applicable | Upper Trapezius Trigger Points | 2022-05-01 | 2022-10-31 | Cairo University | No |
| NCT05039307 | COD, KEN, SDN, South Africa |
General Reference Hospital Mushie Hospital; Bandundu; (HGR) Clinique Ngaliema; Kinshasa; Siaya District Hospital; Siaya; Institute of Endemic Diseases - Dooka hospital; Dooka; Madibeng Centre For Research; Brits; (MCR) |
Prevention of Type 2 Diabetes and Gestational Diabetes Among Women in Kisantu, Democratic Republic of Congo | Interventional | Not Applicable | Gestational Diabetes,Diabetes Mellitus, Type 2 | 2021-10-04 | 2023-10-31 | Institute of Tropical Medicine, Belgium | No |
| NCT04532554 | EGY |
Dar El-Salam Oncology Center; Cairo; |
Growth Hormone in Obese Cases With Covid-19 | Interventional | Phase 4 | Covid19 | 2020-10-26 | 2020-12-20 | ClinAmygate | Yes |
| NCT05220163 | , Kenya |
University of Cape Town; Cape Town; Junju Dispensary; Kilifi; |
Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19 | Interventional | Not Applicable | COVID-19,Tuberculosis,HIV Infections | 2022-02-23 | 2025-03-01 | University of Cape Town | Yes |
| NCT05182021 | EGY |
Mansoura University Hospitals; Mansoura; |
Pregnancy Outcomes on Advanced Maternal Age | Observational | Advanced Maternal Age Pregnancy | 2021-06-01 | 2023-02-01 | Mansoura University | No | |
| NCT04521803 | ZAF |
Nelson Mandela Academic Clinical Research Unit - Nelson Mandela Academic Hospital; Mthatha;(NeMACRU) |
High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis | Interventional | Phase 2 | HIV Status,Tuberculous Pericarditis | 2022-01-06 | 2024-10-31 | University of Cape Town | No |
| NCT04984187 | Effect of High Intensity Laser Versus Plus Exercises | Interventional | Not Applicable | Effect of High Intensity Laser Plus Exercises on Wrist Pain | 2021-07-25 | 2021-08-30 | Badr University | No | ||
| NCT05079659 | EGY |
Assiut University; Assiut; |
Rate , Predictors and Outcome of Chronic Migraine | Observational | Chronic Migraine,Chronic Migraine, Headache | 2021-01-01 | 2023-08-30 | Assiut University | No | |
| NCT02663700 | Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso | Interventional | Phase 1 | Plasmodium Falciparum Infection | 2016-04-07 | 2018-12-17 | National Institute of Allergy and Infectious Diseases (NIAID) | No | ||
| NCT03486691 | Preoperative Ultrasound as a Predictor for Difficulty in Bariatric Surgery | Interventional | Not Applicable | Obesity, Morbid | 2018-02-01 | 2018-08-10 | Minia University | No | ||
| NCT03108625 | South Africa |
Cape Trial Centre; Bellville; |
Continuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of Age | Interventional | Phase 3 | Depressive Disorder, Major | 2017-03-01 | 2020-04-16 | H. Lundbeck A/S | No |
| NCT00002551 | SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed | Interventional | Phase 3 | Colorectal Cancer | 1994-03-01 | 2008-10-01 | Southwest Oncology Group | No | ||
| NCT05350696 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Comparative Study Between ESPB Versus IV Morphine as Postoperative Analgesia After Spine Surgeries . | Interventional | Not Applicable | Discectomy,Vertebral Fractures | 2022-05-16 | 2022-12-01 | Sohag University | No |
| PACTR201412000936255 | Testing an early warning score (EWS) system for recognition of clinical deterioration: multi-site (multi-province) RCT | RCT | Training | 1970-01-01 | 1970-01-01 | UCT Faculty of Health Sciences Clinical Trials Unit | No | |||
| NCT02796326 | Modified Endotracheal Balloon Dilator to Improve Patient Oxygenation and Allow Ventilation During Airway Procedures | Interventional | Not Applicable | Tracheal Stenosis | 2016-10-01 | 2017-09-30 | University of Cape Town | No | ||
| NCT04906538 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Objective Results of Anterior Cruciate Ligament Reconstruction With and Without Internal Suture Augmentation Technique | Interventional | Phase 2,Phase 3 | Anterior Cruciate Ligament Injuries | 2018-09-01 | 2021-04-01 | Ain Shams University | No |
| NCT04923321 | EGY |
NEMROCK Faculty of Medicine - Cairo University; El Azab; |
Taste Supra-thresholds Among a Sample of Depressed Egyptian Adult Under Anti-depressants Therapy | Observational | Taste Disorders | 2021-02-22 | 2021-05-07 | Cairo University | No | |
| PACTR201509001259869 | SLE |
College of Medicine and Allied Health Sciences - University of Sierra Leone; Freetown; |
A Phase II Clinical Trial to Evaluate the Recombinant Human Type 5 Adenovirus Vector Based Ebola Virus Disease Vaccine (Ad5-EBOV) | RCT | Ebola Virus Disease ,Infections and Infestations | 2015-01-10 | 2016-01-04 | Ministry of Health & Sanitation | No | |
| PACTR201610001763265 | ZAF |
Bishop Lavis Day Hospital; Cape Town; |
GeneXpert Performance Evaluation for Linkage to Tuberculosis Care | RCT | Infections and Infestations | 2018-01-10 | 1970-01-01 | University of California San Francisco | No | |
| PACTR201301000465398 | South Africa |
TASK Eden Clinical Research Centre; George; |
Early infant male circumcision using devices | RCT | Early infant circumcision ultimately for HIV prevention,Infections and Infestations,Paediatrics,Surgery,Urological and Genital Diseases | 2013-11-11 | 2013-01-05 | Population Services International | No | |
| PACTR201312000722390 | ZAF |
Allergy Clinic; Western Cape; |
Sisters Antiretroviral therapy Programme for Prevention of HIV ¿ an Integrated Response (SAPPH-IRe) | RCT | Infections and Infestations | 1970-01-01 | 1970-01-01 | Centre for Sexual Health and HIV/AIDS Research Zimbabwe | No | |
| NCT03772509 | Use of Introduction Mode to Improve Interactive Voice Response Surveys in Bangladesh and Tanzania | Interventional | Not Applicable | Noncommunicable Diseases,Surveys and Questionnaires | 2017-06-14 | 2017-08-18 | Johns Hopkins Bloomberg School of Public Health | No | ||
| PACTR202207569764052 | ZAF |
Charlotte Maxeke Johannesburg Academic Hospital; Johannesburg; (CMJAH) |
Does increased peri-operative communication improve patient satisfaction after Total Joint Arthroplasty? A randomised controlled trial | RCT | Orthopaedics | 2019-01-08 | 1970-01-01 | Philani Ntombela | No | |
| NCT03568344 | COD, Democratic Republic of the Congo |
Kinshasa School of Public Health - Universite de Kinshasa; Kinshasa; (KSPH) University of Kinshasa; Kinshasa; |
Community Access to Rectal Artesunate for Malaria | Observational | Malaria | 2018-06-15 | 2021-08-31 | Swiss Tropical & Public Health Institute | No | |
| NCT03864796 | ZAF |
Montana Hospital; West Coast; |
Role of CD11a in Pathogenesis of Primary ITP and Effect of Immunosuppressive Therapy on Its Level | Observational | Idiopathic Thrombocytopenic Purpura | 2019-03-01 | 2021-01-01 | Assiut University | No | |
| NCT02129491 | Egypt |
Pediatric Department Children's Hospital - Faculty of Medicine Ain Shams University; Cairo; |
National Egyptian Network Pediatric Stroke and Hemiplegia Registry | Observational | Perinatal Stroke,Stroke With Hemiparesis,Focal Neurologic Deficits | 2014-01-01 | 2021-12-01 | Ain Shams University | No | |
| NCT05143762 | Preemptive Dexamethasone , Paracetamol on Postoperative Period Following Adeno-tonsillectomy in Pediatric . | Interventional | Phase 2 | Analgesia | 2021-10-15 | 2022-04-01 | Benha University | No | ||
| NCT05344872 | ATC Vs PSV for Ventilatory Weaning of Pediatrics Postcardiac Surgery | Interventional | Not Applicable | Congenital Heart Disease | 2022-04-15 | 2023-06-25 | University of Alexandria | No | ||
| NCT04700072 | KEN, Ethiopia, ZMB, SEN, ZAF, , BDI, MOZ, CMR, EGY, BWA, DZA |
International Cancer Institute; Uasin Gishu; Hawassa University; Awassa; (HU) Malaria Institute at Macha; Choma; Centre Hospitalier Universitaire - Hopital Aristide Le Dantec; Dakar; (CHU) Department of Haematology and Cell Biology - University of the Free State; Bloemfontein; Urban Comprehensive Health Centre; Ile Ife; Hopelands Cancer Centre; Durban; Border Diabetic Centre; East London; Manor Medical Center; Sandton; Mary Potter Oncology Centre; Pretoria; Cooper University Hospital Clinical Research Site; Durban; Cardiology Department - University of Hassan II University; Quartier des Hopitaux; Langenhoven Drive Oncology Centre - Cancercare; Port Elizabeth; Clinical Research Annexe - Kenya Medical Research Institute; Siaya; (KEMRI) Curo Oncology; Pretoria; The Oncology Centre - Onco Care Specialist Oncologists; Durban; Sandton Oncology Cancer Centre; Sandton; Groote Schuur Clinical Research Site; Cape Town; Hospital Regional De Gitega; Gitega; Eastleigh Breast Care Centre; Pretoria; Instituto Nacional de Saúde; Maputo; (INS) Limbe Health Center; Sud-Ouest; Cancer Centre - Tanta University; Tanta; Gaborone Clinical Research Site; Gaborone; Hôpital De Rouiba; Algiers; |
Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02) | Interventional | Phase 1,Phase 2 | Melanoma | 2021-05-03 | 2030-04-03 | Merck Sharp & Dohme LLC | No |
| NCT05514535 | A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE) | Interventional | Phase 3 | Obesity,Diabetes Mellitus, Type 2 | 2022-09-01 | 2024-01-05 | Novo Nordisk A/S | No | ||
| NCT04546581 | Senegal, BWA, EGY, Ethiopia, ZAF, South Africa, Uganda, GHA, ZWE, MAR, ZMB, CMR, SEN, TUN, NGA |
University of Thies; Thies; (UT) Francistown Academic Hospital; Francistown; Mansoura University Hospitals; Mansoura; Hawassa University; Awassa; (HU) First Care Medical Centre; Soweto; Netcare St. Augustine's Hospital; Durban; Melrose House; Cape Town; City Park Medical Centre; Cape Town; Manor Medical Center; Sandton; Africa Health Research Institute; Durban; (AHRI) Mbale Regional Referral Hospital; Mbale; Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region; Chidamoyo Christian Hospital; Karoi; Department of cardiology - Military hospital Marrakech; Marrakech; St. Pauls Mission Hospital; Nchelenge; National Heart Institute; Giza; Winelands Medical Research Centre; Cape Winelands; Douala General Hospital; Douala; Department of Endocrinology - Old Main Building, Groote Schuur Hospital; Cape Town; Infectious and Tropical Diseases Department - Fann Hospital; Dakar; Universitas Hospital; Bloemfontein; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; Medicross Medical Centre Parow; Cape Town; Tygerberg Hospital; Parrow; Institute Of Human Virology Of Nigeria; Abuja; (IHVN) Thomo Clinic; Limpopo; South Valley University; Qena; Kimberley Hospital Complex; Kimberley; Moriana Clinical Research; Free State; Netcare Moot General Hospital; Pretoria; |
Inpatient Treatment With Anti-Coronavirus Immunoglobulin (ITAC) | Interventional | Phase 3 | COVID,COVID-19,SARS-CoV-2,SARS (Severe Acute Respiratory Syndrome) | 2020-10-08 | 2021-05-21 | University of Minnesota | Yes |
| NCT05005130 | ZMB, ZAF, CMR |
Chilenje Level 1 Hospital; Lusaka; George Clinical Study Site; George; Limbe Health Center; Sud-Ouest; |
Task-shifted Adaptation of the WHO-PEN Intervention to Address Cardio-metabolic Complications in People Living With HIV in Zambia | Interventional | Not Applicable | HIV,Non Communicable Diseases | 2021-09-20 | 2022-07-01 | University of North Carolina, Chapel Hill | No |
| NCT05494216 | South Africa |
BioART Fertility Centre; Johannesburg; |
Advanced Sperm Selection Techniques and Their Contribution to Blastocyst Euploidy Rates | Interventional | Not Applicable | Infertility,Sperm DNA Fragmentation | 2022-08-01 | 2023-12-01 | Ganin Fertility Center | No |
| NCT02222493 | ZAF |
Manor Medical Center; Sandton; Life Vincent Pallotti Hospital; Pinelands; |
A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02). | Interventional | Phase 3 | Rheumatoid Arthritis | 2014-08-26 | 2017-06-01 | Pfizer | No |
| NCT04970095 | Egypt |
Al-Azhar University; Cairo; |
Alt-RAMEC Expansion and Protraction by EDO in Cleft Lip and Palate Patient | Interventional | Not Applicable | Cleft Lip and Palate | 2021-07-15 | 2023-07-01 | Faculty of Dental Medicine for Girls | No |
| NCT04951401 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Pattern of Dyslipidemia Among Patients With Acute Coronary Syndrome at Sohag University Hospital | Observational | Acute Coronary Syndrome | 2021-08-01 | 2021-10-31 | Sohag University | No | |
| NCT04789629 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Effect of Low Level Laser Therapy on Hamstring Muscle Tightness and Calf Muscle Spasticity in Cerebral Palsy Children. | Interventional | Not Applicable | Cerebral Palsy | 2020-12-01 | 2021-02-01 | national institute of laser enhanced sciences | No |
| PACTR202105631565416 | NGA |
Ahmadu Bello University Teaching Hospital; Zaria; (ABUTH) |
A RANDOMISED CONTROLLED COMPARISON OF VAGINAL AND ORAL BROMOCRIPTINE IN THE MANAGEMENT OF HYPERPROLACTINEMIA AMONG WOMEN ATTENDING INFERTILITY CLINIC IN ABUTH. | RCT | Obstetrics and Gynecology | 2020-01-11 | 2021-01-08 | Irshad Asma | No | |
| PACTR202007754558749 | Mali |
Bandiagara Malaria Project - University of Bamako; Bamako; (BMP) |
Randomized double-blinded controlled clinical trial to assess the efficacy of Dihydroartemisinin-Piperaquine compared to Sulfadoxine-Pyrimethamine associated to Amodiaquine in Seasonal Malaria Chemoprevention in school aged children from 6-15 years in Mali | RCT | Infections and Infestations | 2020-01-09 | 1970-01-01 | Universite des Sciences des Techniques et des Technologies de Bamako USTTB | No | |
| NCT04959825 | EGY |
Watany Research and Development Center - Watany Eye Hospital; Cairo; (WEH) |
The Role of Preoperative Melatonin in Reducing the Inhaled Isoflurane Requirements in Open Nephrectomy | Interventional | Early Phase 1 | Postoperative Pain | 2021-07-15 | 2022-05-15 | Cairo University | No |
| NCT05243251 | EGY |
Kasr El-Aini Center of Clinical Oncology & Nuclear Medicine - Cairo University; Giza; |
Olanzapine Anorexia Cachexia | Interventional | Phase 3 | Anorexia | 2021-12-25 | 2022-09-01 | Cairo University | No |
| NCT05094726 | ZAF |
New Specialist Outpatient Department; Cape Town; |
Effect of PBM on Functional Capacity and Fatigability in Post Covid-19 Elderly | Interventional | Not Applicable | Post Covid-19 Elderly | 2021-09-08 | 2021-11-15 | Cairo University | Yes |
| NCT05165004 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Effect of Kangaroo Mother Care Versus Hammock Positioning | Interventional | Not Applicable | Behavior, Child | 2021-02-22 | 2021-07-23 | Alexandria University | No |
| NCT04755725 | EGY |
Menoufia University Hospital; Menoufia; |
Epidural Catheter and Surgically Implanted Rectus Sheath Catheter in Management of Postoperative Pain | Interventional | Not Applicable | Postoperative Pain | 2021-01-01 | 2022-12-01 | Menoufia University | No |
| NCT04213053 | Lees Screen in Concomitant Strabismus | Interventional | Not Applicable | Strabismus | 2020-07-01 | 2022-09-01 | Minia University | No | ||
| NCT00766662 | MLI |
Malaria Research and Training Center - University Of Bamako; Bamako; (MRTC) |
Intermittent Preventive Treatment in Infant in Mali | Interventional | Not Applicable | Malaria | 2006-10-01 | 2007-12-01 | University of Bamako | No |
| NCT04554017 | GHA |
Kwame Nkrumah University of Science and Technology; Kumasi; |
Knowledge on Preventive Measures of Hypertension | Interventional | Not Applicable | Hypertension | 2020-03-15 | 2020-03-22 | Garden City University College | No |
| NCT04740385 | TUN |
Department of Anesthesia and Intensive Care - Fattouma Bourguiba Hospital; Monastir; |
Role of Lung Ultrasound in Confirmation of Correct Double Lumen Endotracheal Tube Placement in Thoracic Surgeries | Observational | Diagnostic Accuracy | 2021-02-03 | 2022-06-30 | National Cancer Institute, Egypt | No | |
| NCT05280951 | ZMB, UGA, ZAF, BWA |
Choma District Health Office; Choma; Kasangati Health Center IV; Wakiso; NHC Health Center; Randburg; Thamaga Health Clinic; Thamaga; |
Focused-PPC: An Integrated Postpartum Care, Education, and Support Model for Women in Ghana | Interventional | Not Applicable | Postpartum Care | 2022-02-26 | 2023-06-01 | University of Notre Dame | No |
| PACTR201508001237608 | EGY |
Cancer Center - Menoufiya University; Menoufiya; |
Abnormal uterine bleeding | RCT | Obstetrics and Gynecology,treatment of endometrial hyperplasia without atypia | 2015-01-09 | 2016-01-03 | Faculty of Medicine | No | |
| NCT04801732 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
The Effect of Thoracic Mulligan Mobilization on Sub-acromial Impingement Syndrome | Interventional | Not Applicable | Shoulder Impingement Syndrome | 2021-08-01 | 2021-11-01 | Cairo University | No |
| NCT05336552 | EGY |
University Hospital - Tanta University; Tanta; |
Social Anxiety Disorder in Medical Students in Sohag University | Observational | Social Anxiety Disorder | 2022-05-23 | 2023-06-01 | Sohag University | No | |
| NCT05113628 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Methylene Blue Spray for Identification of Recurrent Laryngeal Nerve and Parathyroid Gland | Interventional | Not Applicable | Methylene Blue,Parathyroid Gland,Recurrent Laryngeal Nerve Injuries | 2020-01-15 | 2021-07-15 | Zagazig University | No |
| NCT03772431 | Uganda, KEN |
Makerere University; Kampala; Centre for Infectious and Parasitic Diseases Control Research - Kenya Medical Research Institute; Busia; (CIPDCR-KEMRI) |
Use of Narrative Voice and Introduction Content to Improve Interactive Voice Response Surveys in Bangladesh and Uganda | Interventional | Not Applicable | Noncommunicable Diseases,Surveys and Questionnaires | 2017-03-26 | 2017-07-17 | Johns Hopkins Bloomberg School of Public Health | No |
| PACTR2008060000861040 | ZWE |
Biomedical Research and Training Institute; Harare; (BRTI) |
An international multicentre controlled clinical trial to evaluate high dose rifapentine and a quinolone in the treatment of pulmonary tuberculosis | CCT | Infections and Infestations | 1970-01-01 | 1970-01-01 | St Georges Hospital Medical School trading as St Georges University of London | No | |
| NCT04698317 | MAR |
Military Hospital Mohamed V; Rabat; |
Beta-Tricalcium Phosphate and Concentrated Growth Factors in Treatment of Intra-bony Defect Randomized Clinical Trial | Interventional | Phase 2 | Chronic Periodontitis,Concentrated Growth Factors,Intrabony Periodontal Defect | 2021-01-01 | 2021-07-01 | Tanta University | No |
| NCT01334190 | ZAF |
FHI 360; Pretoria; |
A Prospective Observational Study of the Performance of Zarin in Kenya | Observational | Contraceptive Usage | 2011-06-01 | 2013-02-01 | FHI 360 | No | |
| NCT04927598 | EGY |
Assiut University; Assiut; |
Predictors and Prognostic Factors of Gullian Barrie Syndrome Outcome | Observational | Guillain-Barre Syndrome | 2020-10-01 | 2022-04-01 | Assiut University | No | |
| NCT04777240 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Characterization of Enterococci | Observational | Samples From Patients With Enterococcal Infections | 2020-02-01 | 2021-03-10 | Sohag University | No | |
| NCT05213871 | EGY |
Misr University for Science and Technology Hospital; Giza; |
Effect of Instrument-assisted Soft Tissue Mobilization Versus Myofascial Release in Treatment of Mechanical Neck Pain | Interventional | Not Applicable | Neck Pain,Soft Tissue Injuries | 2022-02-01 | 2022-03-22 | Cairo University | No |
| NCT04856254 | EGY |
Mansoura University Hospitals; Mansoura; |
Clinical and Ultrasound Score for Evaluation of Previous Cesarean Section Scar | Interventional | Not Applicable | Previous Cesarean Section Scar | 2020-08-01 | 2021-09-01 | Mansoura University | No |
| NCT05431465 | Egypt |
Al-Azhar University; Cairo; |
Wear of Vita Ambria Only Restoration Compared With IPS Emax Onlay Restoration | Interventional | Not Applicable | Dental Wear,Carious Tooth | 2022-07-01 | 2023-08-01 | Al-Azhar University | No |
| NCT02762539 | Omega3 PUFA in Head Trauam | Interventional | Not Applicable | Traumatic Brain Injury | 2016-06-01 | 2018-01-01 | Mansoura University | No | ||
| NCT02610400 | Namibia |
University of Namibia; Windhoek; |
Evaluation of Reactive Focal Mass Drug Administration (rfMDA) +/- Reactive Focal Vector Control (RAVC) in Namibia | Interventional | Phase 3 | Malaria | 2016-02-01 | 2017-12-01 | University of California, San Francisco | No |
| PACTR202203726718710 | Comparison of diclofenac and paracervical block for pain relief during and after hysterosalpingography in women with infertility in South-South Nigeria: a randomised controlled trial | RCT | Obstetrics and Gynecology | 2021-01-04 | 1970-01-01 | Dr. Peter Chibuzor Oriji | No | |||
| NCT04537117 | EGY |
Fayoum University Hospital; Fayoum; |
Knowledge, Attitudes and Clinical Practices of Pediatric Dentists Regarding Covid-19 | Observational | COVID-19 | 2020-04-20 | 2020-05-05 | Fayoum University | Yes | |
| NCT04438642 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
Biological and Esthetic Evaluation of Ceramic Onlay With Different Preparation Designs | Interventional | Not Applicable | Unsatisfactory Restoration of Tooth | 2019-11-09 | 2022-02-01 | Ahmed Adel Mahmoud Gadallah | No |
| NCT04802525 | ZAF |
Intercare Fourways; Sandton; |
A Low-fat Diet Combined With Moderate-intensity Aerobic Exercise Versus Low-fat Diet, Aerobic Exercise Alone on Dyslipidemia and Depression Status in Obese Patients | Interventional | Not Applicable | Dyslipidemias | 2019-10-10 | 2020-01-15 | Cairo University | No |
| NCT05342103 | ZAF |
Gouda Private Clinic; Gouda; |
High Flow Nasal Oxygenation Versus Non-invasive Ventilation for Patients With Blunt Chest Trauma | Interventional | Not Applicable | Chest Trauma | 2021-11-01 | 2022-10-30 | Huda Fahmy Mahmoud, PhD | No |
| NCT04695769 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Combined Ribavirin With Sofosbuvir/Velpatasvir/Voxilaprevir in Retreatment of Chronic Hepatitis C Non-responders | Interventional | Phase 4 | Chronic Hepatitis C | 2020-11-21 | 2021-10-21 | Helwan University | No |
| NCT05138237 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Evaluation of (Surgery and Endoscopy) in Management of Indeterminate Common Bile Duct Stricture | Interventional | Not Applicable | Indeterminate Common Bile Duct Stricture | 2021-08-01 | 2023-02-01 | Sohag University | No |
| NCT04416997 | Rheumatoid Arthritis Hematological Indices | Observational | Serum Albumin Low,Rheumatoid Arthritis | 2020-03-01 | 2023-01-30 | Assiut University | No | |||
| NCT00316329 | Cameroon, Mali, Madagascar |
Centre Hospitalier Universitaire de Yaounde; Yaounde; Bancoumana Clinical Trial Center; Bancoumana; Centre de sant in Tsiroanomandidy; Tsiroanomandidy; |
ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria | Interventional | Phase 3 | Malaria | 2006-03-01 | Sanofi | No | |
| NCT05065320 | SEN, KEN |
Université Cheikh Anta Diop de Dakar; Dakar; (UCAD) University of Nairobi; Nairobi; |
Tools for the Integrated Management of Childhood Illness: Evaluation of Pulse Oximetry and Clinical Decision Support Algorithms in Primary Care. Longitudinal Observational Study, With Embedded Mixed Methods Studies, Cost and Modelled Cost-effectiveness in Kenya, Myanmar and Senegal | Observational | Hypoxia,Oxymetry,Pneumonia,Primary Health Care,Childhood Severe Illness,Referreal and Consultation,Decision Support Systems, Clinical | 2021-08-16 | 2023-06-01 | Swiss Tropical & Public Health Institute | No | |
| NCT00004859 | ZAF |
Netcare Unitas Hospital; Centurion; |
Carboplatin, Paclitaxel, and Radiation Therapy With or Without Thalidomide in Patients With Stage III Non-small Cell Lung Cancer | Interventional | Phase 3 | Lung Cancer | 2000-01-01 | 2010-03-01 | National Cancer Institute (NCI) | No |
| NCT04442633 | EGY |
Cardiology Department - Alexandria University; Alexandria; |
Glutamine With Topical Corticosteroids for Lichen Planus Treatment | Interventional | Not Applicable | Lichen Penis Planus | 2019-04-01 | 2020-01-01 | Hams Hamed Abdelrahman | No |
| NCT02151890 | Egypt |
Al-Azhar University; Cairo; |
Pregnancy After Stem Cell Transplantation in Premature Ovarian Failure | Interventional | Phase 1,Phase 2 | Premature Ovarian Failure | 2012-03-01 | 2014-05-01 | Al-Azhar University | No |
| NCT00335374 | ZAF |
Practice of Dr. JG Kilian Incorporated; Pretoria: Medical School - University of Witwatersrand Faculty of Health Sciences; Johannesburg; (WITS) E13 Renal Unit; Cape Town; Groote Schuur Clinical Research Site; Cape Town; Flexivest Fourteen (14) Research Centre; Bellville; Ward 21 CRS - WITS RHI; Gauteng ; FHI 360; Pretoria; |
An Open Label SLV308 Safety Extension to Study S308.3.003 in Early PD Patients | Interventional | Phase 3 | Early Stage Parkinson's Disease | 2007-08-01 | 2008-11-01 | Solvay Pharmaceuticals | No |
| PACTR201809769868245 | MEGAMBO TRIAL | RCT | School attendance as primary outcome and urogenital symptoms as secondary outcome | 2018-04-11 | 1970-01-01 | London School of Hygiene and Tropical Medicine | No | |||
| NCT04778813 | BFA |
Centre National de Recherche et de Formation sur le Paludisme; Ouagadougou; (CNRFP) |
Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) | Interventional | Phase 4 | Malaria,Burkina Faso | 2021-06-01 | 2022-06-01 | Centre national de recherche et de formation sur le paludisme | No |
| NCT03557281 | An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis | Interventional | Phase 2 | Tuberculosis | 2019-03-27 | 2021-12-14 | GlaxoSmithKline | No | ||
| NCT05062551 | KEN |
Pumwani Maternity Hospital; Nairobi; |
Effectiveness of Three Steps Hysteroscopic Repair of Post Caesarean Isthmocele in Patients With Post Menstrual Spotting | Interventional | Not Applicable | Abnormal Uterine Bleeding | 2021-07-16 | 2021-12-15 | Mervit Sersy | No |
| NCT05310760 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
Effectiveness of Vitamin C Supplementation in Treatment of Rickets | Interventional | Phase 2,Phase 3 | Nutritional Rickets,Bone Turnover Rate Disorder | 2022-03-01 | 2022-08-31 | Cairo University | No |
| NCT02627456 | MLI |
Malaria Research and Training Center - University Of Bamako; Bamako; (MRTC) |
Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) in Healthy African Adults in Mali | Interventional | Phase 1 | Malaria | 2015-12-09 | 2018-07-03 | National Institute of Allergy and Infectious Diseases (NIAID) | No |
| PACTR202111605102515 | Improving under-nutrition through pulses-based nutrition education | RCT | Nutritional, Metabolic, Endocrine | 1970-01-01 | 1970-01-01 | Univeristy of Gondar | No | |||
| NCT03512249 | South Africa |
Aurum Institute; Tembisa; |
Study to Evaluate H56:IC31 in Preventing Rate of TB Recurrence | Interventional | Phase 2 | Tuberculosis, Pulmonary | 2019-01-31 | 2024-12-31 | Aeras | No |
| NCT05034081 | EGY |
Assiut University; Assiut; |
Impact Of Post-Bariatric Body Contouring Procedures on Patient Body Weight and Metabolism | Interventional | Not Applicable | Bariatric Surgery Candidate | 2021-09-01 | 2025-10-30 | Assiut University | No |
| PACTR202112603690065 | Impact of a low-residue diet on bowel cleansing quality before colonoscopy: a prospective single blinded randomized controlled trial. | RCT | Digestive System | 1970-01-01 | 1970-01-01 | Mohamed seghir nekache hospital | No | |||
| NCT00089986 | GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults | Interventional | Phase 2 | Sepsis | 2004-09-01 | 2007-04-15 | GlaxoSmithKline | No | ||
| NCT01459328 | Resource-Sparing Curative Treatment for Rectal Cancer | Interventional | Phase 3 | Rectal Carcinoma | 2009-09-01 | International Atomic Energy Agency | No | |||
| NCT00869700 | ZAF |
Old Main Building Groote Schuur Hospital; Cape Town; |
Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected Adults | Interventional | Phase 4 | Malaria,HIV Infections | 2009-06-01 | 2010-02-01 | University of Cape Town | No |
| PACTR202002466895205 | SDN |
Institute of Endemic Diseases - University of Khartoum; Khartoum; (IEND) |
Efficacy and safety of Glucosamine sulfate and chondroitin sulfate combination in the treatment of haemophilic arthropathy: randomized, double-blind, placebo-controlled trial | RCT | Orthopaedics | 2020-01-03 | 1970-01-01 | Faculty of pharmacy university of khartoum | No | |
| NCT03133975 | Vitamin D Supplementation for Treatment of Dyslipidemia | Interventional | Phase 3 | Dyslipidemias | 2017-04-01 | 2019-07-01 | Mansoura University | No | ||
| NCT04436445 | ZAF |
National District Hospital; Bloemfontein; |
Effect of Neurogenic Acupoint CUPPING ON WOMEN WITH CHRONIC PELVIC PAIN | Interventional | Not Applicable | Chronic Pelvic Pain | 2018-07-15 | 2020-09-01 | Ministry of Health and Population, Egypt | No |
| PACTR202002616299138 | ETH |
Hawassa University Referral Hospital; Awassa; |
Comparison of Spinal Morphine and Transverse Abdominis Plane Block for Postoperative Pain Management in Patients Undergone Cesarean Section Under Spinal Anesthesia at Hawassa University Comphrensive and Specialized Hospital Ethiopia 2019: Randomized control trial | RCT | Anaesthesia,Surgery | 1970-01-01 | 2020-05-05 | Dilla University | No | |
| NCT02261662 | Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV Infection | Interventional | Not Applicable | Vasculitis,Hepatitis C,Lichen Planus,Autoimmune Diseases | 2014-06-01 | 2014-11-01 | Tanta University | No | ||
| NCT05504954 | South Africa |
Desmond Tutu HIV Foundation; Cape Town; |
A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA | Interventional | Not Applicable | Hiv,Sexually Transmitted Infection | 2019-10-26 | 2021-05-15 | University of Illinois at Chicago | No |
| NCT03266549 | EGY |
Department of Dermatology - Assiut University; Assiut; |
Botulinum Toxin Augmented Surgery vs Conventional Surgery in the Management of Large Angle Horizontal Deviations | Interventional | Not Applicable | Large Angle Horizontal Strabismus | 2021-02-20 | 2021-11-30 | Assiut University | No |
| NCT02409680 | COD, KEN |
Kinshasa School of Public Health - Universite de Kinshasa; Kinshasa; (KSPH) School of Medicine - Moi University; Eldoret; |
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN) | Interventional | Not Applicable | Premature Birth | 2016-03-23 | 2019-04-11 | NICHD Global Network for Women's and Children's Health | No |
| NCT05246072 | EGY |
Ain Shams University; Cairo; |
Effect of Combined Use of Ivermectin and Colchicine in COVID-19 Patients | Interventional | Phase 4 | COVID-19 | 2021-11-01 | 2022-02-28 | Ain Shams University | Yes |
| NCT04777006 | Kenya |
Partners in Health and Research Development; Thika; (PHRD) |
Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform | Interventional | Phase 4 | Depressive Disorder | 2021-09-01 | 2024-10-31 | RAND | No |
| PACTR202201600200783 | MAR |
Ain Shams Research Institute; Oujda; |
Long-term health effects of the Shamiri youth mental health program. | RCT | Mental and Behavioural Disorders,Paediatrics | 1970-01-01 | 1970-01-01 | Templeton World Charity Foundation | No | |
| PACTR201609001776292 | ZWE |
Marondera Provincial Hospital; Harare; |
OLECRANON FRACTURE FIXATION: RANDOMIZED CONTROL CLINICAL TRIAL | RCT | Olecranon fracture fixation,Orthopaedics,Surgery | 2016-01-06 | 2017-01-06 | MKA Molepo | No | |
| NCT05061914 | EGY |
University Hospital - Tanta University; Tanta; |
Surgical Options for Management of Pericardial Effusion | Interventional | Not Applicable | Pericardial Effusion | 2016-03-01 | 2021-09-18 | Sohag University | No |
| NCT00119093 | UGA |
Tororo District Hospital; Tororo; |
Home-based AIDS Care Project | Interventional | Not Applicable | HIV Infections | 2003-05-01 | 2009-03-01 | Centers for Disease Control and Prevention | No |
| NCT04837495 | NGA |
Ahmadu Bello University Teaching Hospital; Zaria; (ABUTH) |
Stellate Ganglion Block in Control of Arrhythmia in Laparoscopic Cholecystectomy | Interventional | Not Applicable | Arrythmia,Pain, Acute | 2021-04-30 | 2022-07-31 | Assiut University | No |
| NCT03440385 | ZAF |
Manor Medical Center; Sandton; Mamma Clinic; Cape Town; |
Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease | Interventional | Phase 3 | Crohn Disease | 2018-03-07 | 2024-06-28 | Celgene | No |
| NCT01445938 | Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria | Interventional | Phase 2 | Malaria | 2011-10-01 | 2012-01-01 | Sanofi | No | ||
| NCT04274335 | KEN, South Africa |
Kar Geno Center Kisumu Women Center For Hope; Kisumu; Madibeng Centre For Research; Brits; (MCR) |
Pharmacokinetics and Pharmacodynamics of Tranexamic Acid in Women Having Caesarean Section Birth [WOMAN-PharmacoTXA] | Interventional | Phase 2 | Pregnancy, High Risk | 2020-12-18 | 2021-09-30 | London School of Hygiene and Tropical Medicine | No |
| NCT05517733 | ASSESSMENT OF SOFT TISSUE HEALING OVER IMMEDIATELY PLACED IMPLANT SEALED WITH PLATELETS RICH FIBRIN (PRF) VERSUS DIODE LASER | Interventional | Not Applicable | Immediate Implant Soft Tissue Healing | 2021-06-10 | 2022-06-30 | Nourhan M.Aly | No | ||
| NCT01810731 | KEN |
Siaya District Hospital; Siaya; |
Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya | Interventional | Phase 2,Phase 3 | HIV,Polio,Malaria,Tetanus,Influenza, Human | 2014-04-01 | 2014-04-01 | Centers for Disease Control and Prevention | No |
| NCT04968184 | EGY, COD, ZAF, BWA, Burkina Faso, Nigeria, TUN, South Africa, Tanzania, NAM, TZA, KEN, GHA, NGA, BEN, MAR, SEN, DZA, MOZ, Egypt, GIN, CMR, Kenya, GAB, ETH, ZWE, Malawi |
Clinical Research Center - Cairo University; Giza; General Reference Hospital Masi Manimba Hospital; Bandundu; (HGR) Mediclinic Medforum; Pretoria; Francistown Academic Hospital; Francistown; Clintrial Consultants; Cape Town; Centre for Medical Excellence; Sandton; Queenswood CTC; Pretoria; Charlotte Maxeke Johannesburg Academic Hospital; Johannesburg; (CMJAH) Louis Pasteur Hospital; Pretoria; Centre de Recherche en Santé de Nouna - Ministère de la Santé; Nouna; (CRSN) First Technical University; Ibadan; Farhat Hached Hospital; Sousse; Little Company of Mary Hospital; Pretoria; Synexus Stanza Clinical Research Centre; Mamelodi; Paarl Research Centre; Paarl; Tropical Pesticides Research Institute; Arusha; Corbod Research; Cape Town; Hopelands Cancer Centre; Durban; Namibia Brain Institute; Eros; Netcare Unitas Hospital; Centurion; Kopong Health Clinic; Kopong; Cardiology Clinical Research; Alberton; Clinical Research Unit; Cosmo; (LCS) Misr University for Science and Technology Hospital; Giza; Wits RHI Shandukani Research Centre CRS; Johannesburg; (RHI) Teule Hospital; Muheza; EgyBrit Medical Centre; Cairo; Arthritis Clinical Research Trials; Cape Town; National Hepatology Institute; Cairo; Department of Clinical and Laboratory Research - National Institute for Medical Research; Dodoma; Boland Ethical Research Group; Western Cape; The Urology Hospital; Pretoria; Prime Cure Medicentre; Durban; Scion Clinical Research; Pretoria; Cooper University Hospital Clinical Research Site; Durban; Enhancing Care Foundation; Durban; Eastern and Southern Africa Centre of International Parasite Control - Kenya Medical Research Institute; Nairobi; (ESACIPAC-KEMRI) Poli Clinic; Port Elizabeth; Montana Hospital; West Coast; Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region; Center for Clinical Care and Clinical Research; Abuja; (CCCRN) Centre de Pneumo-Phthysiologie; Cotonou; Drs Gudgeon and Boeddinghaus Associates; Cape Town; Intercare Tyger Valley Healthcare Centre; Bellville; Department of cardiology - Military hospital Marrakech; Marrakech; Hôpital de Fann; Dakar; George Clinical Study Site; George; Centre Pierre-et-Marie-Curie; Sidi M'Hamed; (CPMC) Consultorio Medico Esperanza; Chimoio; International Hospital of Cheikh zaid; Rabat; The Cairo Kidney Center; Cairo; E13 Renal Unit; Cape Town; Health Insurance Hospital; Beni Suef; Centre de Diagnostic et de Traitement de la Tuberculose de Nikki Hopital Sounou-Séro; Nikki; Centre de recherche en épidémiologie, microbiologie et de soins médicaux de Pastoria; Kindia; (CREMS) Medicross Saxby Medical Centre; Centurion; FARMOVS Integrated Research Solutions; Bloemfontein; National Liver Institute - Menoufia University; Shibin el Kom; La Rabta hospital Tunis; Tunis; Health Services Department - University of Benin; Benin; Albert Alberts Stem Cell Transplant Centre; Pretoria; Paediatric Infectious Diseases Clinical Research Unit; Cape Town; (KID-CRU) Worthwhile Clinical Trials - Medinova Merc; Benoni; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; East Central Hospital; Windhoek; Medicross Medical Centre Parow; Cape Town; CHU Ignace Deen; Conakry; University Of Health And Allied Sciences; Ho Volta Region; Nasser Institute for Research and Treatment; Cairo; Centre Hospitalo-Universitaire d'Oran; Oran; (CHU) Clinique Louis Pasteur; Porto-Novo; The Aga Khan University Hospital; Nairobi; Misr Kidney Center; Mohandessin; Kimberley Hospital Complex; Kimberley; Medical Research Unit - Albert Schweitzer Hospital; Lambarene; (MRU) Centre Oncologie Nakhil; Moulay Youssef; Center for Innovative Drug Development and Therapeutic Trials for Africa - Addis Ababa University; Addis Ababa; (CDT-Africa) Intercare Medical and Dental Centre; Lynwood; School of Medicine - Moi University; Eldoret; Urology and Nephrology Centre - Mansoura University Hospitals; El Bostan; Netcare Moot General Hospital; Pretoria; Military Hospital; Accra; Beitbridge District Hospital; Beitbridge; College of Medicine - University of Malawi; Blantyre; Consortium for Health Research and Advanced Training - University of Nigeria; Enugu; (CHERAT) University Hospital - Tanta University; Tanta; Marondera Provincial Hospital; Harare; Library Square Research Unit; Cape Town; |
Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe CKD | Interventional | Phase 3 | Chronic Kidney Diseases | 2021-11-05 | 2025-01-22 | KBP Biosciences | No |
| NCT00731419 | Randomised Trial Comparing Metal and Plastic Biliary Stents Stents for Palliating Malignant Jaundice | Interventional | Phase 4 | Biliary Obstruction | 2007-06-01 | 2009-08-01 | University of Cape Town | No | ||
| NCT00998764 | ZAF |
Netcare St. Augustine's Hospital; Durban; |
A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients | Interventional | Phase 3 | Alzheimer Disease | 2009-12-01 | 2012-11-01 | Pfizer | No |
| NCT03884062 | Egypt |
Egyptian Liver Hospital - Clinical Research Center; Dakahlia; |
Clinical Impacts of Achieving SVR in Patients With Advanced Hepatic Fibrosis Related to Chronic HCV Treated With Direct Acting Antivirals | 2019-03-01 | 2020-03-10 | Egyptian Liver Hospital | No | |||
| NCT01645254 | MLI |
Malaria Research and Training Center - University Of Bamako; Bamako; (MRTC) University of Science Techniques and Technologies of Bamako; Bamako; (USTTB) |
Phase 1b Malaria Clinical Trial Using Argemone Mexicana in Healthy Adults in Mali | Interventional | Phase 1 | Malaria | 2012-09-01 | 2012-11-01 | University of Bamako | No |
| NCT04153851 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Study the Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate | Interventional | Not Applicable | Missing Teeth | 2019-12-01 | 2021-12-31 | Cairo University | No |
| NCT04694677 | DZA |
CHU Hussein Dey Alger; Alger; |
Safety of Tranexamic Acid in Reducing Blood Loss Myomectomy. | Interventional | Not Applicable | Myoma | 2021-01-10 | 2021-09-10 | Aljazeera Hospital | No |
| NCT03782207 | ZAF |
Tara Hospital; Sandton; |
A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice | Observational | Urothelial Carcinoma,Small Cell Lung Cancer,Non-Small Cell Lung Cancer | 2019-02-07 | 2026-12-19 | Hoffmann-La Roche | No | |
| NCT05230316 | EGY |
Fayoum University Hospital; Fayoum; |
Gynecological Symptoms and Health-related Quality of Life in Egyptian Women With SLE | Observational | SLE,Menstrual Irregularity | 2022-01-15 | 2022-04-01 | Fayoum University | No | |
| NCT04927247 | KEN, ZAF, EGY, Nigeria, NGA, Tunisia, Kenya, UGA |
International Cancer Institute; Uasin Gishu; Life Entabeni Hospital; Berea; Banha University Hospital; Qalyoubia; Aminu Kano Teaching Hospital; Kano; (AKTH) Center for Research in Therapeutic Sciences - Strathmore University; Nairobi; (CREATES) Manor Medical Center; Sandton; University of Abuja Teaching Hospital; Abuja; Catholic Caritas Foundation; Abuja; Universitas Academic Hospital; Bloemfontein; Abu Rish Children's Hospital; Cairo; Clinical Research Annexe - Kenya Medical Research Institute; Siaya; (KEMRI) Nigeria Global Health Trials Network - National Hospital Abuja; Abuja Hospital Aziza Othmana; Tunis; Department of Medical Microbiology Parasitology - College of Medicine University of Ibadan; Oyo; Center for Respiratory Diseases Research - Kenya Medical Research Institute; Nairobi; (CRDR - KEMRI) University of Calabar Teaching Hospital; Calabar; Gertrude's Children's Hospital; Nairobi; Hiway Medical Center; Durban; Lagos University Teaching Hospital; Idi Araba; Department of Paediatrics and Child Health - University of Ilorin Teaching Hospital; Ilorin; University of Nigeria; Nsukka; Mont Amba Medical Center - University of Kinshasa; Lemba; |
A Study of a Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive Crises | Interventional | Phase 3 | Sickle Cell Disease,Vaso-occlusive Crisis,Vaso-occlusive Pain Episode in Sickle Cell Disease | 2021-12-13 | 2024-03-11 | Global Blood Therapeutics | No |
| NCT04579341 | EGY |
Ain Shams University; Cairo; |
Probiotics Supplementation Effect on Glucose Homeostasis in Children With Type 1 Diabetes | Interventional | Not Applicable | Diabetes Mellitus, Type 1 | 2018-01-21 | 2020-11-10 | Ain Shams University | No |
| NCT04700124 | EGY, NGA, BWA, KEN, ZMB, Morocco, SEN, GHA, Nigeria, UGA, ETH, ZAF, AGO, , Uganda, TUN, Senegal, MAR, MOZ, Tunisia, DZA, Kenya |
Clinical Research Center - Cairo University; Giza; Princess Marina Hospital; Port Harcourt; Francistown Academic Hospital; Francistown; International Cancer Institute; Uasin Gishu; Choma District Health Office; Choma; Hopital Militaire; Rabat - Salé - Kénitra; Centre Hospitalier Universitaire - Hopital Aristide Le Dantec; Dakar; (CHU) Jos University Teaching Hospital; Plateau State; Dodowa Health Research Centre; Dodowa; (DHRC) First Technical University; Ibadan; Kasangati Health Center IV; Wakiso; Arba Minch General Hospital; Ethiopia; Paarl Research Centre; Paarl; Instituto de Combate e Controlo das Tripanossomiases; Luanda; (ICCT) Allergology Diagnostic Clinical Research Centre; Western Cape; (ADCRU) Hopelands Cancer Centre; Durban; Gatesville Medical Centre; Cape Town; Netcare Unitas Hospital; Centurion; Manor Medical Center; Sandton; Cardiology Clinical Research; Alberton; University of the Free State; Bloemfontein; Department of Radiotherapy - Addington Hospital; Durban; Steve Biko Academic Hospital - University of Pretoria; Pretoria; Kliptown Soweto Clinical Research Site; Johannesburg; (CRS) Centre Hospitalier Régional Spécialisé; Macenta; (CHRS) National Hepatology Institute; Cairo; Catholic Caritas Foundation; Abuja; Mary Potter Oncology Centre; Pretoria; Dr M Duki Research and Trial Site; Kwazulu Natal; Mbale Regional Referral Hospital; Mbale; The Urology Hospital; Pretoria; Polyclinique Taoufik; Tunis; Cooper University Hospital Clinical Research Site; Durban; Hospital General De Grand Yoff; Dakar; (HOGGY) Eastern and Southern Africa Centre of International Parasite Control - Kenya Medical Research Institute; Nairobi; (ESACIPAC-KEMRI) Poli Clinic; Port Elizabeth; Ibn Rochd University Hospital; Casablanca; NEMROCK Faculty of Medicine - Cairo University; El Azab; Durban Lung Centre; Durban; Clinical Research Annexe - Kenya Medical Research Institute; Siaya; (KEMRI) Dermatology Department - Ain Shams University; Cairo; Consultorio Medico Esperanza; Chimoio; Hospital Aziza Othmana; Tunis; Kingsway Medical Centre; Durban; The Oncology Centre - Onco Care Specialist Oncologists; Durban; Enugu State University Teaching Hospital - Damboa Hospital; Borno state; (ESUTH) Siaya District Hospital; Siaya; University Hospital Freiburg and Johannesburg Hospital; Johannesburg; University Of Health And Allied Sciences; Ho Volta Region; Centre Hospitalo-Universitaire d'Oran; Oran; (CHU) Junju Dispensary; Kilifi; Medical and Dental Centre; Randburg; Hiway Medical Center; Durban; Cancer Centre - Tanta University; Tanta; Assiut University; Assiut; School of Medicine - Moi University; Eldoret; Urology and Nephrology Centre - Mansoura University Hospitals; El Bostan; Netcare Moot General Hospital; Pretoria; N1 City Medical Chambers; Cape Town; Gaborone Clinical Research Site; Gaborone; Oncology department - University of Witwatersrand; Johannesburg; Life The Crompton Hospital; Kwazulu Natal; |
Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304) | Interventional | Phase 3 | Muscle Invasive Bladder Cancer | 2021-04-21 | 2026-06-23 | Merck Sharp & Dohme Corp. | No |
| NCT05152511 | TUN |
Abderrahmen Mami Hospital; Tunis; |
Management of Post-circumcision Ischemia Using Hyperbaric Oxygen Therapy | Observational | Post-circumsion Complications | 2017-04-01 | 2020-10-30 | Aswan University Hospital | No | |
| NCT04199286 | Horizontal Strabismus Surgery | Interventional | Not Applicable | Strabismus | 2019-12-21 | 2021-06-14 | Minia University | No | ||
| NCT05198388 | EGY |
Assiut University; Assiut; |
Beta Endorphins,Interleukin 1 and Interleukin 38 in Covid Patients Associated With Neuropsychological Manifestations. | Observational | Covid Patients | 2023-03-01 | 2024-03-30 | Assiut University | Yes | |
| NCT00697164 | Mali |
Gabriel Toure University Hospital; Bamako; |
Randomized Trial of Erythropoietin During Cerebral Malaria | Interventional | Phase 2,Phase 3 | Cerebral Malaria | 2007-10-01 | 2009-03-01 | Claude Bernard University | No |
| NCT01357668 | ZAF |
Panorama Medical Centre; Parow; |
An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis | Observational | Juvenile Idiopathic Arthritis | 2013-01-30 | 2029-01-02 | Bristol-Myers Squibb | No | |
| NCT03496454 | The Gambia |
Medical Research Council Unit The Gambia At London School of Hygiene and Tropical Medicine - Medical Research Council UK; Banjul;(MRCG LSHTM) |
Susceptibility of Gambian Adults to PfSPZ-Challenge Infection in the Controlled Human Malaria Infection Model | Interventional | Not Applicable | Malaria | 2018-03-29 | 2018-12-05 | London School of Hygiene and Tropical Medicine | No |
| NCT04069819 | The Phosphodiesterase 3 Inhibitor Cilostazol as an Adjunct to Antidepressants in Major Depressive Disorder Patients | Interventional | Not Applicable | Major Depressive Disorder | 2019-08-01 | 2021-12-31 | Sadat City University | No | ||
| NCT03284645 | Viral and Antiretroviral Dynamics in HIV-1 Mother-to-Child Transmission Fluids | Observational | Human Immunodeficiency Virus Infection | 2017-12-22 | 2020-09-17 | Obafemi Awolowo University | No | |||
| NCT00122486 | CMR |
Care and Health Program; Yaounde; |
Study of Tenofovir Disoproxil Fumarate (TDF) for Prevention of HIV | Interventional | Phase 2 | HIV Infections | 2004-07-01 | 2006-03-01 | FHI 360 | No |
| NCT05359341 | NGA |
University of Ibadan; Oyo; |
Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients? | Interventional | Not Applicable | Diabete Type 2 | 2020-09-20 | 2022-01-10 | Sadat City University | No |
| NCT04884360 | ZAF |
Groote Schuur Clinical Research Site; Cape Town; |
D9319C00001- 1L OC Mono Global RCT | Interventional | Phase 3 | Ovarian Cancer | 2021-05-31 | 2025-07-02 | AstraZeneca | No |
| PACTR201810672194296 | NGA |
Jos University Teaching Hospital; Plateau State; |
Effects of Specific Treatment of Problems of Spine on Disability and Pain in Patients with Chronic Low Back Pain | RCT | Musculoskeletal Diseases | 2018-05-11 | 2019-08-01 | Nigerian Air Force | No | |
| NCT05277623 | EGY |
Ain Shams University; Cairo; |
Effect of Mannitol on Postreperfusion Syndrome During Living Donor Liver Transplant | Interventional | Early Phase 1 | Liver Transplant Disorder | 2022-03-07 | 2022-09-01 | Ain Shams University | No |
| NCT04767386 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Relation Between Near Point of Convergence and Postural Stability in Subjects With Non Specific Cervical Pain | Observational | Neck Pain | 2018-06-15 | 2020-05-10 | Cairo University | No | |
| NCT00527163 | Mali |
Gabriel Toure University Hospital; Bamako; |
Role of Nitric Oxide in Malaria | Observational | Malaria,Pulmonary Hypertension | 2007-09-04 | 2015-03-30 | National Heart, Lung, and Blood Institute (NHLBI) | No | |
| NCT05539989 | ZAF |
Wits RHI Shandukani Research Centre CRS; Johannesburg; (RHI) Soweto IMPAACT CRS; Johannesburg; Family Clinical Research Unit - Tygerberg Hospital; Tygerberg; (FAM-CRU CRS) |
Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa | Interventional | Phase 1,Phase 2 | Tuberculosis,HIV Infections | 2023-03-31 | 2025-09-30 | International Maternal Pediatric Adolescent AIDS Clinical Trials Group | No |
| NCT01061151 | Evaluating Strategies to Reduce Mother-to-Child Transmission of HIV Infection in Resource-Limited Countries | Interventional | Phase 3 | HIV Infections | 2011-03-01 | 2016-09-30 | National Institute of Allergy and Infectious Diseases (NIAID) | No | ||
| NCT05068167 | EGY |
Galaa Military Hospital; Heliopolis; |
Acute Kidney Injury as a Risk Factor for Myocardial Injury After Non Cardiac Surgery | Observational | Acute Kidney Injury (AKI) | 2019-03-01 | 2020-09-30 | South Egypt Cancer Institute | No | |
| NCT03166943 | the Possible Effect of the Antiviral Inhibitors for Treatment of Hepatitis C Virus Infection in Cardiac Function | Interventional | Not Applicable | Hepatitis | 2017-05-10 | 2020-12-01 | Assiut University | No | ||
| NCT03395184 | TUN, ZAF |
La Rabta hospital Tunis; Tunis; Lenasia Clinical Trial Centre; Johannesburg; |
Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF‑06700841 In Subjects With Moderate To Severe Crohn's Disease | Interventional | Phase 2 | Crohn's Disease | 2018-02-02 | 2023-10-30 | Pfizer | No |
| PACTR202110576221524 | EGY |
Mansoura University Hospitals; Mansoura; |
The analgesic efficacy and opioid sparing effect of erector spinae plane block in scoliosis correction surgery: a randomized controlled trial | RCT | Orthopaedics | 2021-01-11 | 2022-01-11 | Faculty of Medicine Mansoura University | No | |
| NCT05279105 | ZAF, UGA, CMR |
Intercare Fourways; Sandton; Omugo Health Centre IV; Terego; Centre Pasteur du Cameroun; Yaoundé; (CPC) |
Primary Health Care Delivery Models in Conflict Settings of Cameroon and Nigeria | Observational | Models of Care,Primary Health Care,Conflict-Affected Settings | 2022-03-17 | 2023-09-30 | University of Cambridge | No | |
| PACTR201507001178614 | ZMB |
St. Pauls Mission Hospital; Nchelenge; |
Integration of EPI and Pediatric HIV Services for Improved ART Initiation | RCT | Infections and Infestations | 1970-01-01 | 1970-01-01 | Clinton Health Access Initiative | No | |
| NCT03970408 | EGY |
Ain Shams University; Cairo; |
Median Nerve Excursion During Neurodynamic Mobilization | Observational | CTS | 2019-05-01 | 2020-12-01 | Aliaa Rehan Youssef | No | |
| NCT04657640 | School-Based Assessment of Micronutrient Interventions in Adolescents in Burkina Faso | Interventional | Phase 3 | Anemia | 2020-12-11 | 2022-06-30 | Harvard School of Public Health | No | ||
| NCT05161364 | EGY |
University Hospital - Tanta University; Tanta; |
Kinetic Analysis Due to Foot Dysfunction | Observational | Amputation,Neuropathy;Peripheral | 2021-09-13 | 2022-02-01 | Delta University for Science and Technology | No | |
| NCT05382182 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Outcome Of Treatment Of Prostate Cancer at Sohag University Hospital Between 2017 to 2021 | Observational | Prostate Cancer | 2022-06-01 | 2022-12-31 | Sohag University | No | |
| NCT05182346 | ZAF |
Johese Clinical Research; Centurion; |
Acupressure Versus Ischemic Release in Non-specific Neck Pain | Interventional | Not Applicable | Neck Pain,Manual Therapy | 2020-10-20 | 2021-06-13 | Soheir Shehata RezkAllah Samaan | No |
| NCT04961281 | NGA |
Ahmadu Bello University Teaching Hospital; Zaria; (ABUTH) |
Dexmedetomidine Versus Triamcinolone Treatment of Carpal Tunnel Syndrome | Interventional | Not Applicable | Chronic Pain,Carpal Tunnel Syndrome | 2021-07-22 | 2022-08-01 | Assiut University | No |
| PACTR202011812241529 | BFA |
Institut de Recherche en Science de la Sante; Boulkiemdé; |
EFFICACY AND SAFETY OF PYRONARIDINE-ARTESUNATE (PYRAMAX) FOR THE TREATMENT OF FALCIPARUM MALARIA IN AFRICAN PREGNANT WOMEN | CCT | Infections and Infestations | 2020-01-07 | 1970-01-01 | University of Sciences Techniques and Technologies of Bamako | No | |
| NCT05009355 | MAR |
Centre D'oncologie Al Azhar; Quartier Hassan; |
The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis | Interventional | Early Phase 1 | Vitamin C Deficiency | 2019-01-11 | 2022-12-21 | Cairo University | No |
| NCT05021835 | ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation | Interventional | Phase 3 | Inflammation,Cardiovascular Risk,Chronic Kidney Disease | 2021-08-30 | 2025-10-15 | Novo Nordisk A/S | No | ||
| NCT02678117 | Analgesic Potentials of Preoperative Pregabalin,Magnesium Sulphate and Their Combination in Acute Post-thoracotomy Pain | Interventional | Phase 3 | Postoperative Pain | 2015-07-01 | 2019-12-01 | National Cancer Institute, Egypt | No | ||
| NCT00654979 | ZAF |
Universitas Hospital; Bloemfontein; |
A Pivotal Study to Evaluate the Safety and Effectiveness of RMT Medical Technology's SafeFlo® Vena Cava Filter | Interventional | Not Applicable | Pulmonary Embolism | 2003-07-01 | 2008-03-01 | RMT Medical Technologies, Ltd. | No |
| PACTR202106626595700 | Effect of motivational interviewing on glycemic control, self-care management and diabetes related distress among people with type 2 diabetes mellitus in Tigray region, Ethiopia: a randomized controlled trial | RCT | Nutritional, Metabolic, Endocrine | 2021-01-06 | 1970-01-01 | Mekelle university | No | |||
| NCT03513237 | NGA |
Ahmadu Bello University Teaching Hospital; Zaria; (ABUTH) |
Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain | Interventional | Not Applicable | Post Operative Pain | 2018-04-15 | 2018-11-30 | Cairo University | No |
| NCT05351619 | EGY |
Mansoura University Hospitals; Mansoura; |
Implementing Oral Care Bundle on Critical Care Nurses' Practice and Mechanically Ventilated Patients' Outcomes | Interventional | Not Applicable | Ventilator Associated Pneumonia | 2022-02-01 | 2022-11-01 | Mansoura University | No |
| NCT05208918 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Combined Application of Pulsed RF and Steroids to the DRG for PHN | Interventional | Not Applicable | Chronic Pain,Postherpetic Neuralgia | 2022-02-03 | 2022-08-29 | Mansoura University | No |
| NCT01460095 | TZA |
Bagamoyo District Hospital; Bagamoyo; |
Improving Access to HbA1c in Sub Saharan Africa | Interventional | Not Applicable | Diabetes Mellitus | 2009-03-01 | 2011-12-01 | Yaounde Central Hospital | No |
| NCT05056545 | Postpartum Family Planning Program in Rwanda | Interventional | Not Applicable | Family Planning | 2022-08-01 | 2026-03-31 | Emory University | No | ||
| NCT05407883 | Uganda |
Makerere University; Kampala; |
Effectiveness of School Traffic Warden Programme on Road User Behaviour | Interventional | Not Applicable | Driver Yield to Pedestrians | 2022-06-06 | 2022-12-09 | Makerere University | No |
| NCT00113854 | Uganda |
Department of Paediatrics and Child Health - Makerere University College of Health Sciences; Kampala; |
Mannitol as Adjunct Therapy for Childhood Cerebral Malaria | Interventional | Phase 3 | Cerebral Malaria | 2004-10-01 | 2005-05-01 | Makerere University | No |
| NCT04774666 | ZAF, UGA, GMB, Uganda, BWA, COD, TZA, ZMB, EGY, BEN, South Africa |
Life Entabeni Hospital; Berea; Kasangati Health Center IV; Wakiso; Sukuta Health Center; Brikama; Perinatal HIV Research Unit - Chris Hani Baragwanath Academic Hospital; Soweto; (PHRU) Mbale Regional Referral Hospital; Mbale; Independence Surgery; Gaborone; Clinical Research Center of Butembo - Catholic University of Graben; Butembo; Montana Hospital; West Coast; Omugo Health Centre IV; Terego; Nyamagana District Hospital; Mwanza; Kalingalinga Clinic CRS; Lusaka; Faculty of Medicine - Zagazig University; Zagazig; Thamaga Health Clinic; Thamaga; Worthwhile Clinical Trials - Medinova Merc; Benoni; Bugando medical Centre; Mwanza; Hopital de Zone de Natitingou; Natitingou; Virunga General Hospital of Reference; Goma; (HGR) Mbarara Regional Referral Hospital; Mbarara; Mont Amba Medical Center - University of Kinshasa; Lemba; Mulanda Health Centre IV; Tororo; Armansis Medical Centre; Bojanala; |
Caregiver-Assisted Oral Fluid-based HIV Screening in Children: Uganda | Observational | HIV Testing | 2021-04-19 | 2021-10-08 | Catholic Relief Services | No | |
| NCT00197067 | A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Candidate Vaccines RTS,S/AS02D (0.5 mL Dose) and RTS,S/AS02A (0.25 mL Dose) Administered IM According to a 0, 1, 2 Month Vaccination Schedule in Children Aged 3 to 5 Years Living in a Malaria-endemic Region of Mozambique. | Interventional | Phase 1 | Malaria | 2004-03-15 | 2005-04-26 | GlaxoSmithKline | No | ||
| NCT04162587 | EGY |
Mansoura University Hospitals; Mansoura; |
Extracranial Carotid & Intracranial Arterial Stenosis in Ischemic Stroke | Observational | Ischemic Stroke,Carotid Stenosis | 2019-05-01 | 2020-08-01 | Mansoura University Hospital | No | |
| NCT04759937 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Immunochromatography Versus Microscopy for Diagnosis of Entamoeba Histolytica/Dispar Infection. | Observational | Dysentery Amebic | 2021-03-20 | 2021-12-01 | Sohag University | No | |
| NCT00145223 | EGY |
Ain Shams University; Cairo; |
Research for Elim of Filariasis | Observational | W. Bancrofti Filariasis | 2003-08-01 | 2005-07-01 | National Institute of Allergy and Infectious Diseases (NIAID) | No | |
| NCT05532254 | Bioequivalence Study of Aripiprazole in Healthy Adult Subjects Under Fasting Condition | Interventional | Phase 1 | Healthy Subjects | 2021-02-14 | 2021-03-11 | Future University in Egypt | No | ||
| NCT05076929 | EGY |
Ain Shams University; Cairo; |
Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypertension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia | Observational | Fluid Hypovolemia, Cerebrospinal | 2021-05-28 | 2022-03-01 | Ain Shams University | No | |
| NCT04930588 | EGY |
Kasr Al-Ainy Faculty Of Medicine - Cairo University Hospital; Giza; |
Levels of Neuregulin-4 and Its Receptor ErbB4 in Periodontitis Patients With and Without Diabetes Type 2 | Observational | Periodontitis,Diabetes Mellitus | 2021-06-01 | 2023-12-01 | Cairo University | No | |
| PACTR201905790643955 | KEN |
Centre for Biotechnology Research - Kenya Medical Research Institute; Nairobi; (CBRD-KEMRI) |
Effect of enhanced nutrition education of mothers on post-hospital discharge outcomes of children with severe acute malnutrition: a randomized controlled trial | RCT | Nutritional, Metabolic, Endocrine,Paediatrics | 2019-03-05 | 1970-01-01 | Partnership in Health Research Training Program | No | |
| NCT04701320 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Clinical Evaluation of Nano Hydroxyapatite Reinforced Glass Ionomer in Treatment of Root Caries in Geriatric Patients | Interventional | Phase 1 | Dental Restoration Failure | 2019-07-07 | 2021-08-09 | Cairo University | No |
| NCT05181943 | Effectiveness of Photo-biomodulation in the Treatment of Chemotherapy Induced Mucositis | Interventional | Not Applicable | Mucositis | 2020-10-01 | 2021-12-01 | Alexandria University | No | ||
| NCT00500331 | Dose-Ranging Study in Treatment Naive Type 2 Diabetes Mellitus(T2DM) | Interventional | Phase 2 | Diabetes Mellitus, Type 2 | 2007-01-23 | 2008-02-14 | GlaxoSmithKline | No | ||
| NCT05470959 | EGY |
Faculty of Medicine - Minia University; El Menia; |
Bioactive Composite Versus Resin-Modified Glass Ionomer Liners: 2-Year Clinical Trial | Interventional | Not Applicable | Dental Caries | 2019-10-10 | 2021-12-20 | Mansoura University | No |
| NCT01578850 | ZAF |
Life Vincent Pallotti Hospital; Pinelands; Winelands Medical Research Centre; Cape Winelands; |
Study Conducted in Subjects With Rheumatoid Arthritis Who Have Moderate to Severe Disease Activity Despite Methotrexate Therapy With or Without Other Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)for at Least 12 Weeks Prior to Screening | Interventional | Phase 4 | Rheumatoid Arthritis | 2012-07-01 | 2015-03-01 | Pfizer | No |
| NCT04920994 | DZA |
Pediatric Department - Mansoura University Hospitals; Mansoura; |
Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) in Major Abdominal Surgeries | Interventional | Not Applicable | Abdominal Surgery | 2021-08-13 | 2022-07-01 | Sameh Fathy | No |
| NCT04772872 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
NEURODEVELOPMENTAL OUTCOMES OF SINGLETON CONCEIVED FROM FRESH AND FROZEN EMBRYO TRANSFER COMPARED WITH NATURALLY CONCEIVED | Observational | Singeleton Conceived Fresh and Frozen Embryo Transfer (ICSI/IVF), Naturally Conceived | 2021-02-01 | 2022-02-01 | Cairo University | No | |
| NCT03682549 | EGY |
NEMROCK Faculty of Medicine - Cairo University; El Azab; |
Oral Microbiome of Patients With Hepatitis C Virus Infection | Observational | Hepatitis C Viral | 2019-12-01 | 2020-03-14 | Cairo University | No | |
| NCT05403112 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Simultaneous Implant Placement With Autogenous Bone Ring | Interventional | Not Applicable | Bone Graft | 2022-09-01 | 2023-09-01 | Omar Saleh Ahmed Bassed | No |
| NCT04389788 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Treatment of Patients With Periorbital Hyperpigmentation | Interventional | Not Applicable | Periorbital Hypermelanosis | 2020-02-12 | 2020-10-21 | Sohag University | No |
| NCT05552404 | EGY |
Clinical Research Center - Faculty of Medicine Ain Shams University Research Institute; El Mohamady; |
Postdural Puncture Headache Relief With Aminophylline and SPGB | Interventional | Phase 4 | Anesthesia | 2022-10-01 | 2022-12-31 | Ain Shams University | No |
| NCT04946071 | UGA |
Tororo District Hospital; Tororo; |
Reducing HIV-related Stigma in School Children in Northern Uganda | Interventional | Not Applicable | HIV-related Stigma,Health Risk Behaviors,Knowledge, Attitudes, Practice | 2021-05-05 | 2023-09-30 | Thompson Rivers University | No |
| NCT03024957 | EGY |
Assiut University; Assiut; |
Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on Immunity | Interventional | Phase 1,Phase 2 | Immune System Suppression | 2017-01-01 | 2021-02-01 | Assiut University | No |
| NCT04844905 | NGA |
College of Medicine - University of Lagos; Lagos; |
Adjunctive Ivermectin Mass Drug Administration for Malaria Control | Interventional | Phase 3 | Scabies,Hook Worm,Strongyloidiasis,Malaria,Falciparum,Lymphatic Filariasis,Soil Transmitted Helminths,Neglected Tropical Diseases | 2021-05-03 | 2023-08-01 | London School of Hygiene and Tropical Medicine | No |
| NCT03447795 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Alveolar Ridge Preservation Using Autogenous Tooth Graft Versus Autogenous Demineralized Dentin Graft. | Interventional | Not Applicable | Dentin Graft,Alveolar Ridge Preservation,Autogenous Tooth Bone Graft | 2019-02-01 | 2020-06-01 | Cairo University | No |
| PACTR201110000124315 | Controlled comparison of two moxifloxacin containing treatment shortening regimens in pulmonary tuberculosis [retrospectively registered] | RCT | Infections and Infestations | 2008-01-01 | 2009-01-01 | Centre for Medical Microbiology , Royal Free and University College Medical School, Hampstead Campus, Rowland Hill Street | No | |||
| NCT05062681 | EGY |
Pepsico Clinic; El Emameen; |
RCT on the Efficacy of Dexamethasone Versus Methyl Prednisolone in Covid-19 Infected Patients With High Oxygen Flow | Interventional | Phase 4 | COVID-19 Pandemic | 2021-09-15 | 2022-03-15 | Cairo University | Yes |
| NCT04705558 | MAR |
Military Hospital Mohamed V; Rabat; |
Combination of Ketogenic Diet and Exercise on Prediabetes in Female With Normal Weight | Interventional | Not Applicable | PreDiabetes | 2020-07-20 | 2021-02-10 | Badr University | No |
| NCT03032367 | South Africa |
TASK Clinical Research Centre; Bellville |
TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study) | Interventional | Early Phase 1 | Tuberculosis | 2016-11-10 | 2017-01-11 | International Maternal Pediatric Adolescent AIDS Clinical Trials Group | No |
| NCT05504525 | EGY |
Ain Shams University; Cairo; |
Fascia Iliaca Versus Quadratus Lumborum Block for Pain Management in Total Hip Replacement. | Interventional | Not Applicable | Postoperative Opioid Requirements in Patients With Traumatic Fracture Hip | 2022-05-30 | 2022-10-01 | Ain Shams University | No |
| NCT04938063 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Association Between Functional Impairment and Parenting Stress Among Children Diagnosed With Diplegic Cerebral Palsy | Observational | Cerebral Palsy,Parent-Child Relations | 2021-01-01 | 2021-06-15 | Cairo University | No | |
| NCT04767412 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Inspiratory Muscle Training and Physical Fitness in Children With Down Syndrome Randomized Control Trial | Interventional | Not Applicable | Down Syndrome | 2020-09-03 | 2021-01-21 | Cairo University | No |
| NCT04514055 | EGY |
NEMROCK Faculty of Medicine - Cairo University; El Azab; |
Connective Tissue Graft Wall Technique in Management of Cairo's RT2 and RT3 With Intra-bony Defects | Interventional | Not Applicable | Recession, Gingival | 2020-10-01 | 2022-06-01 | Cairo University | No |
| NCT05338164 | EGY |
Faculty of Medicine - Zagazig University; Zagazig; |
Prophylactic Cerclage for Twin Pregnancy With Shortened Cervix | Interventional | Not Applicable | Preterm Birth,Cervical Shortening,Twin Pregnancy With Antenatal Problem | 2021-12-20 | 2023-08-15 | Zagazig University | No |
| PACTR201907658492123 | EGY |
Faculty of Medicine - Minia University; El Menia; |
The effect of Sildenafil on the success rate of ovulation induction with Clomiphene citrate versusClomiphene Citrate alone in unexplained infertility patients | RCT | Obstetrics and Gynecology | 2018-01-06 | 1970-01-01 | faculty of medicine suez canal university | No | |
| NCT04824131 | ZWE, UGA, ZAF |
Spilhaus Clinical Research Site - Zimbabwe National Family Planning Council Clinic; Harare; (ZNFPC CRS) Johns Hopkins University Research Collaboration - Makere University; Kampala; (MUJHU) Ward 21 CRS - WITS RHI; Gauteng ; |
Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Females - A Sub-study of HPTN 084 | Interventional | Phase 2 | HIV Infections | 2020-11-04 | 2024-05-01 | National Institute of Allergy and Infectious Diseases (NIAID) | No |
| NCT05293652 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Effect of Hydrocortisone Iontophoresis Versus Hydrocortisone Phonophoresis On Post Surgical Scar | Interventional | Not Applicable | Scar,Iontophoresis,Phonophoresis,Hydrocortisone | 2021-09-01 | 2022-02-15 | Horus University | No |
| NCT04182399 | EGY |
Ain Shams University; Cairo; |
Role of Zonisamide in Advanced Parkinson's Disease (PD) in Egyptian Population: Pilot Study | Interventional | Not Applicable | Parkinson Disease | 2020-04-01 | 2023-01-01 | Ain Shams University | No |
| NCT05150535 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
One Week Adjuvant Radiotherapy for Breast Cancer | Interventional | Not Applicable | Breast Carcinoma | 2021-10-01 | 2023-10-01 | Sohag University | No |
| PACTR202001691971779 | ZAF |
Department of Paediatrics and Child Health; Panorama; |
Effectiveness of Tranexamic acid in reducing blood loss during myomectomy in federal Medical Centre, Owerri: A randomised controlled trial | RCT | Obstetrics and Gynecology | 1970-01-01 | 1970-01-01 | Onwukwe Emeka | No | |
| PACTR201301000454298 | GHA |
Department of Paediatrics and Child Health - University of Health and Allied Sciences Trafalgar Campus; Volta Region; |
Identifying interventions to improve immunization safety (4ISAFETY) | RCT | Immunization safety,Injury, Occupational Diseases, Poisoning | 2012-03-12 | 1970-01-01 | Cameroon Ministry of Public Health | No | |
| NCT05031923 | EGY |
Faculty of Medicine - Kafr El-sheikh University; Kafr el-Sheikh; |
Treatment of Intrabony Defects With Simvastatin and Antimicrobial Photodynamic Therapy | Interventional | Not Applicable | Simvastatin,Periodontal Diseases,Photodynamic Therapy | 2021-10-01 | 2022-08-01 | Kafrelsheikh University | No |
| NCT02434939 | Uganda |
Mulago Sickle Cell Clinic; Kampala; |
Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers | Interventional | Phase 4 | Acute Pain,Sickle Cell Crisis | 2015-06-01 | 2016-02-01 | Makerere University | No |
| NCT04885673 | MAR |
Center Hospitalier Universitaire Mohammed VI; Marrakesh; (CHU) |
High Flow Nasal Cannula in Comparison to Apneic Oxygenation During Foreign Body Removal by Rigid Bronchoscope | Interventional | Not Applicable | Anesthesia | 2021-04-25 | 2021-07-25 | Ain Shams University | No |
| NCT04830748 | EGY |
Faculty of Physical Therapy - Pharos University; Alexandria; |
Effect of Mechanical Traction and Therapeutic Exercises in Treatment of Primary Knee Osteoarthritis | Interventional | Not Applicable | Knee Osteoarthritis | 2022-05-01 | 2023-05-01 | Cairo University | No |
| NCT04077411 | Approaches and Decisions for Acute Pediatric TBI Trial | Observational | Severe Traumatic Brain Injury | 2014-02-20 | 2018-08-28 | University of Pittsburgh | No | |||
| NCT00223990 | Kenya |
Kombewa Clinical Research Centre; Kisumu; |
Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine | Interventional | Phase 2 | Malaria, Falciparum | 2005-04-08 | 2007-06-01 | U.S. Army Medical Research and Development Command | No |
| NCT05383924 | EGY |
Ain Shams University; Cairo; |
Intrauterine Contraceptive Device Insertion During Cesarean Section (CS) Versus Delayed Insertion | Interventional | Not Applicable | IUD,Contraception | 2021-05-01 | 2022-06-05 | Ain Shams Maternity Hospital | No |
| NCT02435992 | ZAF |
Louis Pasteur Hospital; Pretoria; Endocare Research; Cape Town; Manor Medical Center; Sandton; Tiervlei Trial Centre; Bellville; (TTC) Mamma Clinic; Cape Town; |
Safety and Efficacy Trial of RPC1063 for Moderate to Severe Ulcerative Colitis | Interventional | Phase 3 | Ulcerative Colitis | 2015-06-17 | 2020-06-17 | Celgene | No |
| NCT05381233 | EGY |
Pepsico Clinic; El Emameen; |
Quality of Life and Functional Performance in Children With Spastic Cerebral Palsy | Interventional | Not Applicable | Evaluations | 2022-01-01 | 2024-07-15 | Sara Shawki Mohamed | No |
| PACTR202009754904918 | Hemoperfusion for organophosphate poisoning in critically ill patients- A randomized trial. | RCT | Injury, Occupational Diseases, Poisoning | 2020-06-01 | 2022-03-02 | Jalo | No | |||
| NCT00003175 | Fluorouracil in Treating Patients With Recurrent or Metastatic Bladder Cancer | Interventional | Phase 2 | Bladder Cancer,Urethral Cancer,Transitional Cell Cancer of the Renal Pelvis and Ureter | 1997-12-01 | 2009-03-01 | Medical Research Council | No | ||
| NCT04094493 | EGY |
Assiut University; Assiut; |
Vit D Role in Post Thyroidectomy Hypocalcemia | Interventional | Early Phase 1 | Thyroid Diseases | 2019-10-01 | 2020-09-30 | Assiut University | No |
| NCT04643288 | Egypt |
Paediatric Hospital - Cairo University; Cairo; |
Nanocrystalline Hydroxyapatite Bone Substitute for Treating Periodontal Intrabony Defects | Interventional | Not Applicable | Chronic Periodontitis | 2018-09-01 | 2020-05-25 | Weam Ahmed Elbattawy | No |
| NCT05137288 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Intrathecal Atropine Versus Intravenous Ondasetron in Post Operative Nausea Due to Intrathecal Morphine | Interventional | Not Applicable | Perineal Surgery | 2021-12-01 | 2022-08-01 | Sohag University | No |
| NCT05045417 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
IL17 in Systemic Lupus Erythematosus Patients: Association With Disease Activity and Organ Damage | Observational | Systemic Lupus Erythematosus | 2021-10-01 | 2022-04-30 | Sohag University | No | |
| NCT02469298 | Safety, Tolerability and Clinical Effect of Danirixin in Adults With Influenza | Interventional | Phase 2 | Virus Diseases | 2015-06-01 | 2016-04-25 | GlaxoSmithKline | No | ||
| NCT05246176 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Ultrasonography as a Single Tool for Guided Percutaneous Transhepatic Biliary Drainage in Obstructive Jaundice | Interventional | Not Applicable | Obstructive Jaundice | 2021-07-15 | 2022-08-15 | Sohag University | No |
| PACTR201511001360267 | EGY |
Cancer Center - Menoufiya University; Menoufiya; |
Comparison between adenosine and magnesium sulphate as adjuvants for transversus abdominis plane block A prospective randomized controlled trial. | RCT | Anaesthesia,Transversus abdominis plane block | 1970-01-01 | 1970-01-01 | Minoufiya University | No | |
| NCT05170490 | TUN |
Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; |
Long Term Follow up of Chronic HCV Patients Receiving DAAS | Observational | Chronic Hepatitis c | 2018-06-01 | 2023-03-01 | Sohag University | No | |
| NCT04627636 | ZAF |
Jan S Marais Hospital; Bellville; |
MTPr With Shockwave on Pain & Function of SHS in Stroke | Interventional | Not Applicable | Stroke | 2019-10-01 | 2020-01-30 | October 6 University | No |
| PACTR201903762696119 | Nigeria |
Murtala Muhammad Specialist Hospital; Kano; |
Effects of Walking Exercise on Brain-Derived Neurotrophic Factor, Cognition, Participation and Quality of Life among Stroke Survivors | RCT | Nervous System Diseases | 1970-01-01 | 1970-01-01 | Bayero Uiversity Kano | No | |
| NCT02684019 | Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure | Interventional | Phase 3 | Lack of Drug Action | 2016-01-01 | 2016-11-01 | Theodor Bilharz Research Institute | No | ||
| PACTR201301000445375 | Uganda |
Infectious Diseases Institute; Kampala; (IDI) |
Atorvastastin and HIV associated immune activation | RCT | Infections and Infestations,Nutritional, Metabolic, Endocrine | 2012-10-12 | 1970-01-01 | Damalie Nakanjako | No | |
| NCT04716283 | BWA |
University of Botswana/McMAsters University; Gaborone; |
Sleep Quality Among Students in Sohag University. | Observational | Sleep | 2021-08-15 | 2022-10-10 | Sohag University | No | |
| NCT05101954 | Platelet Rich Fibrin and Concentrated Growth Factors on Osseointegration of Immediate Implants | Interventional | Not Applicable | Dental Implants,Tooth Extraction | 2020-10-01 | 2021-08-17 | Hams Hamed Abdelrahman | No | ||
| NCT03614533 | BFA |
Groupe de Recherche Action en Santé; Ouagadougou; (GRAS) |
Typhoid Conjugate Vaccine Trial Among Children Younger Than 2 Years in Ouagadougou, Burkina Faso | Interventional | Phase 2 | Typhoid | 2018-12-03 | 2019-08-22 | University of Maryland, Baltimore | No |
| NCT04589845 | EGY, NGA, KEN, MAR, ZAF, Burkina Faso, TUN, DZA, Uganda, SEN, GAB, Egypt, ETH, ZWE, GIN, BDI, Algeria, MOZ, South Africa, SWZ, Malawi, LBR, UGA, BEN |
Clinical Research Center - Cairo University; Giza; Princess Marina Hospital; Port Harcourt; International Cancer Institute; Uasin Gishu; Clinique des Nations Unies; Rabat; Clintrial Consultants; Cape Town; Netcare St. Augustine's Hospital; Durban; Louis Pasteur Hospital; Pretoria; Cairo Gastrointestinal tract and liver Center; Cairo; Netcare Greenacres Hospital; Port Elizabeth; Centre de Recherche en Santé de Nouna - Ministère de la Santé; Nouna; (CRSN) Kenyatta National Hospital; Nairobi; (KNH) Urban Comprehensive Health Centre; Ile Ife; Hopelands Cancer Centre; Durban; City Park Medical Centre; Cape Town; Department of Radiotherapy - Addington Hospital; Durban; Vaal Triangle Oncology Centre - Clinical and Radiation Oncologists A.B.J. Inc; Vereeniging; Service Haematologie - Hopital Militaire de Tunis; Tunis; Stikland Hospital; Cape Town; Mary Potter Oncology Centre; Pretoria; Pediatric Department - Mansoura University Hospitals; Mansoura; Boland Ethical Research Group; Western Cape; Mbale Regional Referral Hospital; Mbale; Cooper University Hospital Clinical Research Site; Durban; Niakhar Demographic Surveillance System; Dakar;(DS IDR) Western Cape Clinical Trials; Western Cape; Life Flora Clinic; Roodepoort; Southern Cross Hospital; Cape Town; Hopital d'Enfants University of Medecine; Rabat; Poli Clinic; Port Elizabeth; Durban Paediatric HIV Clinical Research Site; KwaZulu-Natal; (CRS) Chef du service de parasitologie et de paludisme; Libreville; Montana Hospital; West Coast; Paediatric Hospital - Cairo University; Cairo; Deborah Retief Memorial Hospital; Mochudi; Hawassa University Referral Hospital; Awassa; Abu Rish Children's Hospital; Cairo; Chidamoyo Christian Hospital; Karoi; New Specialist Outpatient Department; Cape Town; Immanuel General Hospital; Eket; Durban Medical Centre; Durban; George Clinical Study Site; George; Health Insurance Hospital; Beni Suef; Centre de recherche en épidémiologie, microbiologie et de soins médicaux de Pastoria; Kindia; (CREMS) The Oncology Centre - Onco Care Specialist Oncologists; Durban; National Liver Institute - Menoufia University; Shibin el Kom; Sandton Oncology Cancer Centre; Sandton; Institut National d'Oncologie; Bujumbura; Gertrude's Children's Hospital; Nairobi; Centre Hôpital Universitaire - University Hospital Farhat Hached; Sousse; Durban Adult Human Immunodeficiency Virus Clinical Research Site; Durban; (HIV CRS) Centre Anti-Cancer; Annaba; Instituto Nacional de Saúde; Maputo; (INS) NESTRA KLINIkAL; Ibadan; Cancer Centre - Tanta University; Tanta; Maternal Adolescent and Child Health Institute - Research Unit; Durban; (MatCH) Rondebosch Oncology Centre - CancerCare; Cape Town; Eswatini Prevention Center Clinical Research Site; Mbabane; (CRS) School of Medicine - Moi University; Eldoret; College of Medicine - University of Malawi; Blantyre; ELWA Medical Center; Monrovia; Mont Amba Medical Center - University of Kinshasa; Lemba; Allergy Clinic; Western Cape; Department of Oncology - University of the Free State; Bloemfontein; University of California San Francisco Collaborative Research Program - University of Zimbabwe; Harare; (UZ-UCSF) University Hospital - Tanta University; Tanta; University of California San Francisco - Kenya Medical Research Institute; Kisumu; (UCSF-KEMRI) Hôpital de la Mère et de l'Enfant Lagune; Cotonou; Centre D'oncologie Al Azhar; Quartier Hassan; Eastern Cape Oncology Center; Port Elizabeth; |
Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study | Interventional | Phase 2 | Solid Tumors | 2021-01-18 | 2032-09-25 | Hoffmann-La Roche | No |
| NCT04768829 | EGY |